APOE Genotype Results in Differential Effects on the Peripheral Clearance of Amyloid-β42 in APOE Knock-in and Knock-out Mice

Name: Work Video:
Duration: 3 min 30 s
Description: The ε4 allele of apolipoprotein E (APOE) is currently the major genetic risk factor identified for Alzheimer's disease (AD). Previous in vivo data from our laboratory has demonstrated that amyloid-β (Aβ) is rapidly removed from the plasma by the live
Matthew J. Sharman; Michael Morici; Eugene Hone; Tamar Berger; Kevin Taddei; Ian Martins; Wei Ling Florence Lim; Sajla Singh; Markus R. Wenk; Jorge Ghiso; Joseph D. Buxbaum; Sam Gandy; Ralph N. Martins
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