Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W18760785', 'doi': 'https://doi.org/10.2741/3882', 'title': 'Induction and patterning of intramembranous bone', 'display_name': 'Induction and patterning of intramembranous bone', 'publication_year': 2011, 'publication_date': '2011-01-01', 'ids': {'openalex': 'https://openalex.org/W18760785', 'doi': 'https://doi.org/10.2741/3882', 'mag': '18760785', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21622205'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2741/3882', 'pdf_url': 'https://article.imrpress.com/bri/Landmark/articles/pdf/Landmark3882.pdf', 'source': {'id': 'https://openalex.org/S185455647', 'display_name': 'Frontiers in bioscience', 'issn_l': '1093-4715', 'issn': ['1093-4715', '1093-9946', '1094-3935'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320848', 'host_organization_name': 'Frontiers in Bioscience', 'host_organization_lineage': ['https://openalex.org/P4310320848'], 'host_organization_lineage_names': ['Frontiers in Bioscience'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://article.imrpress.com/bri/Landmark/articles/pdf/Landmark3882.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5039641843', 'display_name': 'Tamara A. Franz‐Odendaal', 'orcid': 'https://orcid.org/0000-0003-4883-2677'}, 'institutions': [{'id': 'https://openalex.org/I179301192', 'display_name': 'Mount Saint Vincent University', 'ror': 'https://ror.org/03g3p3b82', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I179301192']}], 'countries': ['CA'], 'is_corresponding': True, 'raw_author_name': 'Tamara A Franz-Odendaal', 'raw_affiliation_strings': ['Department of Biology Mount Saint Vincent University 166 Bedford Highway, Halifax Nova Scotia B3M 2J6 Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology Mount Saint Vincent University 166 Bedford Highway, Halifax Nova Scotia B3M 2J6 Canada', 'institution_ids': ['https://openalex.org/I179301192']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5039641843'], 'corresponding_institution_ids': ['https://openalex.org/I179301192'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.005, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 80, 'citation_normalized_percentile': {'value': 0.699569, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '16', 'issue': '1', 'first_page': '2734', 'last_page': '2734'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11919', 'display_name': 'Molecular Mechanisms of Tooth Development and Morphogenesis', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11919', 'display_name': 'Molecular Mechanisms of Tooth Development and Morphogenesis', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10268', 'display_name': 'Notch Signaling Pathway in Development and Disease', 'score': 0.9955, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12009', 'display_name': 'Hedgehog Signaling in Development and Cancer', 'score': 0.9921, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/intramembranous-ossification', 'display_name': 'Intramembranous ossification', 'score': 0.9921077}, {'id': 'https://openalex.org/keywords/endochondral-ossification', 'display_name': 'Endochondral ossification', 'score': 0.97996414}, {'id': 'https://openalex.org/keywords/tooth-development', 'display_name': 'Tooth Development', 'score': 0.504674}, {'id': 'https://openalex.org/keywords/bone-development', 'display_name': 'Bone development', 'score': 0.48432222}], 'concepts': [{'id': 'https://openalex.org/C188945261', 'wikidata': 'https://www.wikidata.org/wiki/Q10746904', 'display_name': 'Intramembranous ossification', 'level': 2, 'score': 0.9921077}, {'id': 'https://openalex.org/C17938293', 'wikidata': 'https://www.wikidata.org/wiki/Q3312710', 'display_name': 'Endochondral ossification', 'level': 3, 'score': 0.97996414}, {'id': 'https://openalex.org/C2778842504', 'wikidata': 'https://www.wikidata.org/wiki/Q1121544', 'display_name': 'Ossification', 'level': 2, 'score': 0.837927}, {'id': 'https://openalex.org/C2780550940', 'wikidata': 'https://www.wikidata.org/wiki/Q502730', 'display_name': 'Cartilage', 'level': 2, 'score': 0.5909237}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.5305118}, {'id': 'https://openalex.org/C2992191624', 'wikidata': 'https://www.wikidata.org/wiki/Q265868', 'display_name': 'Bone development', 'level': 2, 'score': 0.48432222}, {'id': 'https://openalex.org/C98045186', 'wikidata': 'https://www.wikidata.org/wiki/Q205663', 'display_name': 'Process (computing)', 'level': 2, 'score': 0.4720491}, {'id': 'https://openalex.org/C2779300802', 'wikidata': 'https://www.wikidata.org/wiki/Q13147', 'display_name': 'Skull', 'level': 2, 'score': 0.45543513}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36361647}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.3330347}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.32765633}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.15848878}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.11682567}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001846', 'descriptor_name': 'Bone Development', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D010012', 'descriptor_name': 'Osteogenesis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019521', 'descriptor_name': 'Body Patterning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019521', 'descriptor_name': 'Body Patterning', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D019521', 'descriptor_name': 'Body Patterning', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001846', 'descriptor_name': 'Bone Development', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001846', 'descriptor_name': 'Bone Development', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D050659', 'descriptor_name': 'Core Binding Factor Alpha 1 Subunit', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050659', 'descriptor_name': 'Core Binding Factor Alpha 1 Subunit', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D005346', 'descriptor_name': 'Fibroblast Growth Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005346', 'descriptor_name': 'Fibroblast Growth Factors', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D053823', 'descriptor_name': 'Hedgehog Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053823', 'descriptor_name': 'Hedgehog Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051957', 'descriptor_name': 'MSX1 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051957', 'descriptor_name': 'MSX1 Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010012', 'descriptor_name': 'Osteogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010012', 'descriptor_name': 'Osteogenesis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D055758', 'descriptor_name': 'SOX9 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055758', 'descriptor_name': 'SOX9 Transcription Factor', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.2741/3882', 'pdf_url': 'https://article.imrpress.com/bri/Landmark/articles/pdf/Landmark3882.pdf', 'source': {'id': 'https://openalex.org/S185455647', 'display_name': 'Frontiers in bioscience', 'issn_l': '1093-4715', 'issn': ['1093-4715', '1093-9946', '1094-3935'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320848', 'host_organization_name': 'Frontiers in Bioscience', 'host_organization_lineage': ['https://openalex.org/P4310320848'], 'host_organization_lineage_names': ['Frontiers in Bioscience'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21622205', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2741/3882', 'pdf_url': 'https://article.imrpress.com/bri/Landmark/articles/pdf/Landmark3882.pdf', 'source': {'id': 'https://openalex.org/S185455647', 'display_name': 'Frontiers in bioscience', 'issn_l': '1093-4715', 'issn': ['1093-4715', '1093-9946', '1094-3935'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320848', 'host_organization_name': 'Frontiers in Bioscience', 'host_organization_lineage': ['https://openalex.org/P4310320848'], 'host_organization_lineage_names': ['Frontiers in Bioscience'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 67, 'referenced_works': ['https://openalex.org/W1508055754', 'https://openalex.org/W1571756582', 'https://openalex.org/W1587942099', 'https://openalex.org/W1602919907', 'https://openalex.org/W1647268241', 'https://openalex.org/W1772573500', 'https://openalex.org/W1939720492', 'https://openalex.org/W1963641861', 'https://openalex.org/W1965144118', 'https://openalex.org/W1966006200', 'https://openalex.org/W1971943177', 'https://openalex.org/W1972649530', 'https://openalex.org/W1975513365', 'https://openalex.org/W1987965038', 'https://openalex.org/W1989392905', 'https://openalex.org/W1990196985', 'https://openalex.org/W1990880194', 'https://openalex.org/W1993163303', 'https://openalex.org/W1994067429', 'https://openalex.org/W1995499476', 'https://openalex.org/W1997812904', 'https://openalex.org/W2004969069', 'https://openalex.org/W2014803172', 'https://openalex.org/W2018474375', 'https://openalex.org/W2025046506', 'https://openalex.org/W2027023100', 'https://openalex.org/W2032394856', 'https://openalex.org/W2035653659', 'https://openalex.org/W2035934212', 'https://openalex.org/W2041632453', 'https://openalex.org/W2046020232', 'https://openalex.org/W2046108663', 'https://openalex.org/W2046935528', 'https://openalex.org/W2052420344', 'https://openalex.org/W2052485937', 'https://openalex.org/W2052877772', 'https://openalex.org/W2061876556', 'https://openalex.org/W2064366726', 'https://openalex.org/W2065295375', 'https://openalex.org/W2086943246', 'https://openalex.org/W2090896044', 'https://openalex.org/W2094911771', 'https://openalex.org/W2100455164', 'https://openalex.org/W2101821342', 'https://openalex.org/W2102894828', 'https://openalex.org/W2104593931', 'https://openalex.org/W2108274213', 'https://openalex.org/W2110341920', 'https://openalex.org/W2112590513', 'https://openalex.org/W2115799477', 'https://openalex.org/W2122433264', 'https://openalex.org/W2122558235', 'https://openalex.org/W2129313036', 'https://openalex.org/W2135892692', 'https://openalex.org/W2138448751', 'https://openalex.org/W2140034535', 'https://openalex.org/W2140099557', 'https://openalex.org/W2156501038', 'https://openalex.org/W2156925261', 'https://openalex.org/W2186400656', 'https://openalex.org/W2188175856', 'https://openalex.org/W2334655667', 'https://openalex.org/W2343551766', 'https://openalex.org/W2344009374', 'https://openalex.org/W2346534881', 'https://openalex.org/W2404637315', 'https://openalex.org/W4253173013'], 'related_works': ['https://openalex.org/W3111436710', 'https://openalex.org/W2979256684', 'https://openalex.org/W2353378266', 'https://openalex.org/W2160769459', 'https://openalex.org/W2106666142', 'https://openalex.org/W2106253741', 'https://openalex.org/W2039419642', 'https://openalex.org/W2025253407', 'https://openalex.org/W18760785', 'https://openalex.org/W1774377056'], 'abstract_inverted_index': {'The': [0], 'primary': [1], 'focus': [2, 122], 'of': [3, 41, 58, 71, 82, 95], 'this': [4, 75, 119], 'article': [5], 'is': [6, 51, 65], 'to': [7, 33, 44, 68], 'review': [8], 'intramembranous': [9, 54, 90], 'bone': [10], 'development,': [11, 63], 'that': [12, 15, 50], 'is,': [13], 'ossification': [14, 22, 42], 'takes': [16], 'place': [17], 'directly.': [18], 'Comparisons': [19], 'with': [20, 24, 130], 'endochondral': [21, 102], '(ossification': [23], 'a': [25, 100, 115], 'cartilage': [26], 'precursor)': [27], 'will': [28], 'be': [29], 'made': [30], 'in': [31, 74, 114], 'order': [32], 'illustrate': [34], 'the': [35, 46, 72, 80, 83, 93, 96], 'differences': [36], 'between': [37], 'these': [38, 112], 'two': [39], 'modes': [40], 'and': [43, 92, 127], 'highlight': [45], 'comparatively': [47], 'sparse': [48], 'information': [49], 'available': [52], 'about': [53], 'ossification.': [55], 'Despite': [56], 'decades': [57], 'research': [59, 73], 'into': [60], 'understanding': [61], 'skeletal': [62, 108, 128], 'there': [64], 'still': [66], 'much': [67], 'learn.': [69], 'Most': [70], 'area': [76], 'has': [77], 'focused': [78], 'on': [79, 124], 'development': [81, 94], 'calvariae': [84], '(or': [85], 'skull': [86], 'bones)': [87], 'as': [88, 99], 'typical': [89, 101], 'bones': [91, 98], 'limb': [97], 'bones.': [103], 'Few': [104], 'studies': [105], 'investigate': [106], 'other': [107], 'elements': [109], 'or': [110], 'compare': [111], 'processes': [113], 'systematic': [116], 'manner.': [117], 'In': [118], 'review,': [120], 'I': [121], 'primarily': [123], 'condensation': [125], 'formation': [126], 'patterning': [129], 'specific': [131], 'examples': [132], 'from': [133], 'different': [134], 'organisms.': [135]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W18760785', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 11}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-19T10:15:21.979757', 'created_date': '2016-06-24'}