Title: Larvicidal Activity ofAcacia nilotica Extracts and Isolation ofD-Pinitol - A Bioactive Carbohydrate
Abstract: Chemistry & BiodiversityVolume 2, Issue 5 p. 684-688 Research Article Larvicidal Activity of Acacia nilotica Extracts and Isolation of D-Pinitol – A Bioactive Carbohydrate Rohini Chaubal, Rohini Chaubal T. R. Ingle Research Laboratory, Department of Chemistry, Sir Parshurambhau College, 411 030 Pune, Maharashtra, India (phone: +91-20-25440968)Search for more papers by this authorPushpa V. Pawar, Pushpa V. Pawar Department of Entomology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorGeeta D. Hebbalkar, Geeta D. Hebbalkar Department of Entomology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorVijay B. Tungikar, Vijay B. Tungikar Department of Entomology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorVedavati G. Puranik, Vedavati G. Puranik Center For Materials Characterization, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorVishnu H. Deshpande, Vishnu H. Deshpande Organic Chemistry Technology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorNirmala R. Deshpande, Nirmala R. Deshpande [email protected] T. R. Ingle Research Laboratory, Department of Chemistry, Sir Parshurambhau College, 411 030 Pune, Maharashtra, India (phone: +91-20-25440968)Search for more papers by this author Rohini Chaubal, Rohini Chaubal T. R. Ingle Research Laboratory, Department of Chemistry, Sir Parshurambhau College, 411 030 Pune, Maharashtra, India (phone: +91-20-25440968)Search for more papers by this authorPushpa V. Pawar, Pushpa V. Pawar Department of Entomology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorGeeta D. Hebbalkar, Geeta D. Hebbalkar Department of Entomology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorVijay B. Tungikar, Vijay B. Tungikar Department of Entomology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorVedavati G. Puranik, Vedavati G. Puranik Center For Materials Characterization, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorVishnu H. Deshpande, Vishnu H. Deshpande Organic Chemistry Technology, National Chemical Laboratory, 411 008 Pune, IndiaSearch for more papers by this authorNirmala R. Deshpande, Nirmala R. Deshpande [email protected] T. R. Ingle Research Laboratory, Department of Chemistry, Sir Parshurambhau College, 411 030 Pune, Maharashtra, India (phone: +91-20-25440968)Search for more papers by this author First published: 18 May 2005 https://doi.org/10.1002/cbdv.200590044Citations: 49AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract A low-molecular-weight, sugar-like compound other than glucose, fructose, sucrose, or myo-inositol showing lipophilic nature was isolated from the EtOH extract of Acacia nilotica. The structure of the compound was determined by spectral methods. This alicyclic polyalcohol was found to be D-pinitol (=3-O-methyl-D-chiro-inositol; 1). The configuration of the compound was confirmed by single-crystal X-ray analysis. The compound 1 is known from Soybean, Australian mangroves, Fagonia indica, Arachis hypogaea, etc., but we have isolated this compound for the first time from the aerial parts of A. nilotica. Very few references have been cited for compound 1 for its entomological activity, and there are no reports on mosquitoes. Therefore, the crude extracts of A. nilotica were tested for its biological activity against mosquito larvae. Acetone extract at 500-ppm concentration showed chronic toxicity against Aedes aegypti and Culex quinquefasciatus IVth instar mosquito larvae. Such a biological activity has been observed for the first time for this plant. This study could be a stepping stone to a solution for destroying larval species as well as consumption of such a widely grown, problem weed, A. nilotica. This larvicidal agent, since it is derived from plant, is eco-friendly, cost effective, non-hazardous to non-target organisms and would be safe unlike commercially available insecticides. Citing Literature Volume2, Issue5May 2005Pages 684-688 RelatedInformation
Publication Year: 2005
Publication Date: 2005-05-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 80
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