Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1857603824', 'doi': 'https://doi.org/10.18632/oncotarget.2320', 'title': 'Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory Complex-I activity via Bcl-2 family proteins', 'display_name': 'Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory Complex-I activity via Bcl-2 family proteins', 'publication_year': 2014, 'publication_date': '2014-08-06', 'ids': {'openalex': 'https://openalex.org/W1857603824', 'doi': 'https://doi.org/10.18632/oncotarget.2320', 'mag': '1857603824', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25115399', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4226696'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.2320', 'pdf_url': 'https://www.oncotarget.com/article/2320/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/2320/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100656606', 'display_name': 'Eun Mi Kim', 'orcid': 'https://orcid.org/0000-0002-7131-9049'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Eun Mi Kim', 'raw_affiliation_strings': ["Division of Life and Pharmaceutical Science, Ewha Woman's University Seoul, Korea", "Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea; Division of Life and Pharmaceutical Science, Ewha Woman's University Seoul, Korea."], 'affiliations': [{'raw_affiliation_string': "Division of Life and Pharmaceutical Science, Ewha Woman's University Seoul, Korea", 'institution_ids': ['https://openalex.org/I138925566']}, {'raw_affiliation_string': "Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea; Division of Life and Pharmaceutical Science, Ewha Woman's University Seoul, Korea.", 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058007838', 'display_name': 'Jong Kuk Park', 'orcid': 'https://orcid.org/0000-0001-5135-0033'}, 'institutions': [{'id': 'https://openalex.org/I4210088603', 'display_name': 'Korea Institute of Radiological and Medical Sciences', 'ror': 'https://ror.org/00a8tg325', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210088603']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jong Kuk Park', 'raw_affiliation_strings': ['Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.', 'institution_ids': ['https://openalex.org/I4210088603']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068010675', 'display_name': 'Sang‐Gu Hwang', 'orcid': 'https://orcid.org/0000-0002-3402-3708'}, 'institutions': [{'id': 'https://openalex.org/I4210088603', 'display_name': 'Korea Institute of Radiological and Medical Sciences', 'ror': 'https://ror.org/00a8tg325', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210088603']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sang-Gu Hwang', 'raw_affiliation_strings': ['Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.', 'institution_ids': ['https://openalex.org/I4210088603']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028262111', 'display_name': 'Wun‐Jae Kim', 'orcid': 'https://orcid.org/0000-0002-8060-8926'}, 'institutions': [{'id': 'https://openalex.org/I163753206', 'display_name': 'Chungbuk National University', 'ror': 'https://ror.org/02wnxgj78', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I163753206']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Wun-Jae Kim', 'raw_affiliation_strings': ['Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Korea', 'institution_ids': ['https://openalex.org/I163753206']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020316005', 'display_name': 'Zheng Gang Liu', 'orcid': 'https://orcid.org/0000-0001-8157-9349'}, 'institutions': [{'id': 'https://openalex.org/I4210149717', 'display_name': 'Center for Cancer Research', 'ror': 'https://ror.org/05bjen692', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884', 'https://openalex.org/I4210149717']}, {'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Zheng-Gang Liu', 'raw_affiliation_strings': ['Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA;'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA;', 'institution_ids': ['https://openalex.org/I4210149717', 'https://openalex.org/I4210140884', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101539185', 'display_name': 'Sang Won Kang', 'orcid': 'https://orcid.org/0000-0001-6446-163X'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sang Won Kang', 'raw_affiliation_strings': ["Division of Life and Pharmaceutical Science, Ewha Woman's University Seoul, Korea."], 'affiliations': [{'raw_affiliation_string': "Division of Life and Pharmaceutical Science, Ewha Woman's University Seoul, Korea.", 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5056158186', 'display_name': 'Hong-Duck Um', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210088603', 'display_name': 'Korea Institute of Radiological and Medical Sciences', 'ror': 'https://ror.org/00a8tg325', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210088603']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hong-Duck Um', 'raw_affiliation_strings': ['Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Division of Radiation Cancer Biology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.', 'institution_ids': ['https://openalex.org/I4210088603']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.571, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 43, 'citation_normalized_percentile': {'value': 0.849424, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '5', 'issue': '18', 'first_page': '8452', 'last_page': '8465'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Dynamics and Reactive Oxygen Species Regulation', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/p53', 'display_name': 'p53', 'score': 0.510541}, {'id': 'https://openalex.org/keywords/tumor-suppression', 'display_name': 'Tumor Suppression', 'score': 0.506018}], 'concepts': [{'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.6475172}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.5317211}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.44623053}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.42298383}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.392481}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.27966768}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.20559496}], 'mesh': [{'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D042967', 'descriptor_name': 'Electron Transport Complex I', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019253', 'descriptor_name': 'Proto-Oncogene Proteins c-bcl-2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051017', 'descriptor_name': 'Apoptosis Regulatory Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051017', 'descriptor_name': 'Apoptosis Regulatory Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042967', 'descriptor_name': 'Electron Transport Complex I', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D042967', 'descriptor_name': 'Electron Transport Complex I', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054730', 'descriptor_name': 'Protein Interaction Domains and Motifs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019253', 'descriptor_name': 'Proto-Oncogene Proteins c-bcl-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019253', 'descriptor_name': 'Proto-Oncogene Proteins c-bcl-2', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047368', 'descriptor_name': 'Tumor Burden', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051028', 'descriptor_name': 'bcl-2-Associated X Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051028', 'descriptor_name': 'bcl-2-Associated X Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051020', 'descriptor_name': 'bcl-X Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051020', 'descriptor_name': 'bcl-X Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.2320', 'pdf_url': 'https://www.oncotarget.com/article/2320/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4226696', 'pdf_url': 'https://europepmc.org/articles/pmc4226696?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226696', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25115399', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.2320', 'pdf_url': 'https://www.oncotarget.com/article/2320/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1892647714', 'https://openalex.org/W1964719993', 'https://openalex.org/W1968338931', 'https://openalex.org/W1979262539', 'https://openalex.org/W1991510903', 'https://openalex.org/W1994102692', 'https://openalex.org/W1997646834', 'https://openalex.org/W2002408632', 'https://openalex.org/W2002936090', 'https://openalex.org/W2005155951', 'https://openalex.org/W2020285793', 'https://openalex.org/W2022665529', 'https://openalex.org/W2024101233', 'https://openalex.org/W2034680056', 'https://openalex.org/W2038137963', 'https://openalex.org/W2039856166', 'https://openalex.org/W2041398967', 'https://openalex.org/W2042024021', 'https://openalex.org/W2042070921', 'https://openalex.org/W2043249221', 'https://openalex.org/W2051233997', 'https://openalex.org/W2060584880', 'https://openalex.org/W2063694826', 'https://openalex.org/W2071109537', 'https://openalex.org/W2073915650', 'https://openalex.org/W2077725209', 'https://openalex.org/W2083017377', 'https://openalex.org/W2085523227', 'https://openalex.org/W2085612532', 'https://openalex.org/W2087877138', 'https://openalex.org/W2092229793', 'https://openalex.org/W2094616662', 'https://openalex.org/W2094694817', 'https://openalex.org/W2103619814', 'https://openalex.org/W2106009840', 'https://openalex.org/W2112230021', 'https://openalex.org/W2115986380', 'https://openalex.org/W2117935886', 'https://openalex.org/W2122341467', 'https://openalex.org/W2125284551', 'https://openalex.org/W2126917392', 'https://openalex.org/W2133732014', 'https://openalex.org/W2138004837', 'https://openalex.org/W2153530617'], 'related_works': ['https://openalex.org/W4234157524', 'https://openalex.org/W2788277189', 'https://openalex.org/W2151865869', 'https://openalex.org/W2130076355', 'https://openalex.org/W2119695867', 'https://openalex.org/W2117258802', 'https://openalex.org/W2082860237', 'https://openalex.org/W2013243191', 'https://openalex.org/W1993764875', 'https://openalex.org/W1990804418'], 'abstract_inverted_index': {'//': [0, 89], 'Eun': [1], 'Mi': [2], 'Kim': [3, 16], '1,2': [4], ',': [5, 10, 14, 18, 22], 'Jong': [6], 'Kuk': [7], 'Park': [8], '1': [9, 13, 30, 31], 'Sang-Gu': [11], 'Hwang': [12], 'Wun-Jae': [15], '3': [17, 58], 'Zheng-Gang': [19], 'Liu': [20], '4': [21, 70], 'Sang': [23], 'Won': [24], 'Kang': [25], '2': [26, 46], 'and': [27, 50, 187, 203, 207, 216, 222, 228, 254, 271, 279, 282], 'Hong-Duck': [28, 86], 'Um': [29], 'Division': [32, 47], 'of': [33, 39, 48, 60, 63, 80, 127, 138, 180, 194, 233, 276], 'Radiation': [34], 'Cancer': [35, 73, 76], 'Biology,': [36], 'Korea': [37, 45, 57, 69], 'Institute': [38], 'Radiological': [40], '&': [41], 'Medical': [42], 'Sciences,': [43], 'Seoul,': [44, 56], 'Life': [49], 'Pharmaceutical': [51], 'Science,': [52], 'Ewha': [53], 'Woman’s': [54], 'University': [55], 'Department': [59], 'Urology,': [61], 'College': [62], 'Medicine,': [64], 'Chungbuk': [65], 'National': [66, 75, 78], 'University,': [67], 'Cheongju,': [68], 'Center': [71], 'for': [72, 220], 'Research,': [74], 'Institute,': [77], 'Institutes': [79], 'Health,': [81], 'Bethesda,': [82], 'MD,': [83], 'USA': [84], 'Correspondence:': [85], 'Um,': [87], 'email:': [88], 'Keywords': [90], ':': [91, 101, 106, 111], 'p53,': [92], 'Bcl-2': [93, 165, 255, 272], 'family': [94, 166, 256], 'proteins,': [95], 'respiratory': [96, 181], 'complex-I,': [97, 182, 284], 'cell': [98, 147, 208], 'invasion': [99, 148], 'Received': [100], 'June': [102], '27,': [103], '2014': [104, 109, 114], 'Accepted': [105], 'August': [107, 112], '05,': [108], 'Published': [110], '06,': [113], 'Abstract': [115], 'Although': [116], 'the': [117, 125, 135, 230, 250], 'p53': [118, 145, 169, 236, 253, 270], 'tumor': [119], 'suppressor/transcription': [120], 'factor': [121], 'often': [122], 'accumulates': [123], 'in': [124, 197, 246, 261], 'cytoplasm': [126], 'healthy': [128], 'cells,': [129], 'limited': [130], 'information': [131], 'is': [132, 162], 'available': [133], 'on': [134], 'cytoplasmic': [136, 144, 231], 'function': [137, 161, 232], 'p53.': [139], 'Here,': [140], 'we': [141], 'show': [142], 'that': [143, 159, 213, 252], 'suppresses': [146, 238], 'by': [149, 164, 241], 'reducing': [150], 'mitochondrial': [151], 'reactive': [152], 'oxygen': [153], 'species': [154], '(ROS)': [155], 'levels.': [156], 'Analysis': [157], 'revealed': [158], 'this': [160], 'mediated': [163], 'proteins:': [167], 'Cytoplasmic': [168], 'binds': [170, 176], 'Bcl-w,': [171], 'liberating': [172], 'Bax,': [173, 223], 'which': [174], 'then': [175], 'ND5,': [177, 195, 286], 'a': [178, 267], 'subunit': [179], 'thereby': [183], 'suppressing': [184], 'complex-I': [185, 226, 239], 'activity': [186, 227, 240], 'thus': [188], 'ROS': [189, 205, 277], 'production.': [190], 'The': [191], 'G13289A': [192], 'mutation': [193], 'identified': [196], 'cancer': [198], 'patients,': [199], 'prevents': [200], 'Bax/ND5': [201], 'interactions': [202], 'promotes': [204], 'production': [206, 278], 'invasion.': [209], 'We': [210], 'also': [211, 237], 'showed': [212], 'Bcl-X': [214], 'L': [215], 'Bak': [217], 'can': [218], 'substitute': [219], 'Bcl-w': [221], 'respectively,': [224], 'regulating': [225], 'supporting': [229], 'p53;': [234], 'nuclear': [235], 'inducing': [242], 'Bax': [243], 'expression.': [244], 'Studies': [245], 'animal': [247], 'models': [248], 'support': [249], 'notion': [251], 'proteins': [257, 273], 'exhibit': [258], 'these': [259], 'functions': [260], 'vivo': [262], '.': [263], 'This': [264], 'study': [265], 'demonstrates': [266], 'link': [268], 'between': [269], 'as': [274, 287], 'regulators': [275], 'cellular': [280], 'invasiveness,': [281], 'reveals': [283], 'especially': [285], 'their': [288], 'functional': [289], 'target.': [290]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1857603824', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 3}], 'updated_date': '2024-08-21T15:04:54.639725', 'created_date': '2016-06-24'}