Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1841926691', 'doi': 'https://doi.org/10.18632/oncotarget.3102', 'title': 'A three-protein signature and clinical outcome in esophageal squamous cell carcinoma', 'display_name': 'A three-protein signature and clinical outcome in esophageal squamous cell carcinoma', 'publication_year': 2014, 'publication_date': '2014-12-31', 'ids': {'openalex': 'https://openalex.org/W1841926691', 'doi': 'https://doi.org/10.18632/oncotarget.3102', 'mag': '1841926691', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25605255', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4467159'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.3102', 'pdf_url': 'https://www.oncotarget.com/article/3102/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/3102/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101064029', 'display_name': 'Hui-Hui Cao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}, {'id': 'https://openalex.org/I32574673', 'display_name': 'Shantou University', 'ror': 'https://ror.org/01a099706', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I32574673']}, {'id': 'https://openalex.org/I4210120522', 'display_name': 'Shantou University Medical College', 'ror': 'https://ror.org/02gxych78', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210120522']}, {'id': 'https://openalex.org/I4210105182', 'display_name': "Zhuhai People's Hospital", 'ror': 'https://ror.org/01k1x3b35', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210105182']}], 'countries': ['CN', 'GB'], 'is_corresponding': False, 'raw_author_name': 'Hui-Hui Cao', 'raw_affiliation_strings': ["Departments of Pathology, Zhuhai People's Hospital, Zhuhai, Guangdong, P.R. China", 'Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong, P.R. China', 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I170203145']}, {'raw_affiliation_string': 'Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong, P.R. China', 'institution_ids': ['https://openalex.org/I32574673', 'https://openalex.org/I4210120522']}, {'raw_affiliation_string': "Departments of Pathology, Zhuhai People's Hospital, Zhuhai, Guangdong, P.R. China", 'institution_ids': ['https://openalex.org/I4210105182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100784918', 'display_name': 'Shiyi Zhang', 'orcid': 'https://orcid.org/0000-0002-9375-5992'}, 'institutions': [{'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shi-Yi Zhang', 'raw_affiliation_strings': ['Department of Oncology Surgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology Surgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100847335', 'display_name': 'Jin‐Hui Shen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jin-Hui Shen', 'raw_affiliation_strings': ['Department of Pathology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101809762', 'display_name': 'Zhi‐Yong Wu', 'orcid': 'https://orcid.org/0000-0003-2535-1619'}, 'institutions': [{'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhi-Yong Wu', 'raw_affiliation_strings': ['Department of Oncology Surgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology Surgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103549748', 'display_name': 'Jian‐Yi Wu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}, {'id': 'https://openalex.org/I32574673', 'display_name': 'Shantou University', 'ror': 'https://ror.org/01a099706', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I32574673']}], 'countries': ['CN', 'GB'], 'is_corresponding': False, 'raw_author_name': 'Jian-Yi Wu', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I170203145']}, {'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I32574673']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000808868', 'display_name': 'Shaohong Wang', 'orcid': 'https://orcid.org/0000-0001-5421-2971'}, 'institutions': [{'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shao-Hong Wang', 'raw_affiliation_strings': ['Department of Pathology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038387396', 'display_name': 'En‐Min Li', 'orcid': 'https://orcid.org/0000-0001-6375-3614'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}, {'id': 'https://openalex.org/I32574673', 'display_name': 'Shantou University', 'ror': 'https://ror.org/01a099706', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I32574673']}], 'countries': ['CN', 'GB'], 'is_corresponding': False, 'raw_author_name': 'En-Min Li', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I170203145']}, {'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I32574673']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5023997325', 'display_name': 'Li‐Yan Xu', 'orcid': 'https://orcid.org/0000-0002-1618-4292'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}, {'id': 'https://openalex.org/I32574673', 'display_name': 'Shantou University', 'ror': 'https://ror.org/01a099706', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I32574673']}], 'countries': ['CN', 'GB'], 'is_corresponding': False, 'raw_author_name': 'Li-Yan Xu', 'raw_affiliation_strings': ['Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.'], 'affiliations': [{'raw_affiliation_string': 'The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I170203145']}, {'raw_affiliation_string': 'Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong, P.R. China.', 'institution_ids': ['https://openalex.org/I32574673']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.354, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 42, 'citation_normalized_percentile': {'value': 0.856272, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '6', 'issue': '7', 'first_page': '5435', 'last_page': '5448'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10619', 'display_name': 'Preoperative Chemoradiotherapy for Esophageal Cancer', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10619', 'display_name': 'Preoperative Chemoradiotherapy for Esophageal Cancer', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10417', 'display_name': 'Advancements in Lung Cancer Research', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11287', 'display_name': 'Genomic Landscape of Cancer and Mutational Signatures', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/esophageal-carcinoma', 'display_name': 'Esophageal Carcinoma', 'score': 0.45912}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7578581}, {'id': 'https://openalex.org/C2994415158', 'wikidata': 'https://www.wikidata.org/wiki/Q372701', 'display_name': 'Esophageal squamous cell carcinoma', 'level': 3, 'score': 0.52883756}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.49366722}, {'id': 'https://openalex.org/C2779742542', 'wikidata': 'https://www.wikidata.org/wiki/Q372701', 'display_name': 'Esophageal cancer', 'level': 3, 'score': 0.43621087}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.42751414}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.35366338}, {'id': 'https://openalex.org/C61434518', 'wikidata': 'https://www.wikidata.org/wiki/Q932510', 'display_name': 'General surgery', 'level': 1, 'score': 0.34059036}], 'mesh': [{'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000556', 'qualifier_name': 'secondary', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': True}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': True}, {'descriptor_ui': 'D016016', 'descriptor_name': 'Proportional Hazards Models', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000465', 'descriptor_name': 'Algorithms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015331', 'descriptor_name': 'Cohort Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007124', 'descriptor_name': 'Immunoenzyme Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053208', 'descriptor_name': 'Kaplan-Meier Estimate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008207', 'descriptor_name': 'Lymphatic Metastasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060787', 'descriptor_name': 'Neoplasm Grading', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009367', 'descriptor_name': 'Neoplasm Staging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015996', 'descriptor_name': 'Survival Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046888', 'descriptor_name': 'Tissue Array Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.3102', 'pdf_url': 'https://www.oncotarget.com/article/3102/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4467159', 'pdf_url': 'https://europepmc.org/articles/pmc4467159?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467159', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25605255', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.3102', 'pdf_url': 'https://www.oncotarget.com/article/3102/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.88, 'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W105975759', 'https://openalex.org/W1577537697', 'https://openalex.org/W1970476748', 'https://openalex.org/W1977669212', 'https://openalex.org/W1990893849', 'https://openalex.org/W1991944021', 'https://openalex.org/W1993573257', 'https://openalex.org/W2004049335', 'https://openalex.org/W2007861835', 'https://openalex.org/W2009671859', 'https://openalex.org/W2017334656', 'https://openalex.org/W2021173510', 'https://openalex.org/W2021809712', 'https://openalex.org/W2024678072', 'https://openalex.org/W2034400622', 'https://openalex.org/W2043671423', 'https://openalex.org/W2057730598', 'https://openalex.org/W2058741607', 'https://openalex.org/W2059234749', 'https://openalex.org/W2062641317', 'https://openalex.org/W2072068823', 'https://openalex.org/W2084001490', 'https://openalex.org/W2088496607', 'https://openalex.org/W2092868756', 'https://openalex.org/W2093735335', 'https://openalex.org/W2104593681', 'https://openalex.org/W2105882193', 'https://openalex.org/W2121277505', 'https://openalex.org/W2126415088', 'https://openalex.org/W2126697949', 'https://openalex.org/W2133740757', 'https://openalex.org/W2135696440', 'https://openalex.org/W2140065103', 'https://openalex.org/W2148916294', 'https://openalex.org/W2158402998', 'https://openalex.org/W2159621438', 'https://openalex.org/W2161817637', 'https://openalex.org/W2164118025', 'https://openalex.org/W2167593091', 'https://openalex.org/W2168145925', 'https://openalex.org/W2171208997', 'https://openalex.org/W2438426036', 'https://openalex.org/W3150076638'], 'related_works': ['https://openalex.org/W2887332714', 'https://openalex.org/W2567367013', 'https://openalex.org/W2392925209', 'https://openalex.org/W2364196712', 'https://openalex.org/W2363769048', 'https://openalex.org/W2359489959', 'https://openalex.org/W2350028111', 'https://openalex.org/W2186113122', 'https://openalex.org/W2006692432', 'https://openalex.org/W1523310174'], 'abstract_inverted_index': {'//': [0, 142, 146], 'Hui-Hui': [1], 'Cao': [2], '1,2,6,*': [3], ',': [4, 8, 12, 16, 20, 24], 'Shi-Yi': [5], 'Zhang': [6], '3,*': [7], 'Jin-Hui': [9], 'Shen': [10], '4,*': [11], 'Zhi-Yong': [13], 'Wu': [14, 18], '3': [15, 67, 329], 'Jian-Yi': [17], '1,5': [19, 27], 'Shao-Hong': [21], 'Wang': [22], '4': [23, 86], 'En-Min': [25, 139], 'Li': [26], 'and': [28, 108, 186, 242, 272, 298, 305, 321, 359], 'Li-Yan': [29, 143], 'Xu': [30], '1,2': [31], '1': [32, 244], 'The': [33, 199, 285], 'Key': [34], 'Laboratory': [35], 'of': [36, 56, 69, 78, 88, 96, 106, 121, 180, 201, 210, 225, 282, 287, 293, 327, 338], 'Molecular': [37, 109], 'Biology': [38], 'for': [39, 319], 'High': [40], 'Cancer': [41], 'Incidence': [42], 'Coastal': [43], 'Chaoshan': [44], 'Area,': [45], 'Shantou': [46, 59, 72, 76, 90, 94, 111], 'University': [47, 60, 112], 'Medical': [48, 61, 113], 'College,': [49, 62, 114], 'Shantou,': [50, 63, 82, 100, 115], 'Guangdong,': [51, 64, 83, 101, 116, 127], 'P.R.': [52, 65, 84, 102, 117, 128], 'China': [53, 66, 85, 103, 118, 129], '2': [54], 'Institute': [55], 'Oncologic': [57], 'Pathology,': [58, 89, 122], 'Departments': [68, 87, 120], 'Oncology': [70], 'Surgery,': [71], 'Central': [73, 91], 'Hospital,': [74, 92, 125], 'Affiliated': [75, 93], 'Hospital': [77, 95], 'Sun': [79, 97], 'Yat-sen': [80, 98], 'University,': [81, 99], '5': [104], 'Department': [105], 'Biochemistry': [107], 'Biology,': [110], '6': [119], 'Zhuhai': [123], "People's": [124], 'Zhuhai,': [126], '*': [130], 'These': [131], 'authors': [132], 'contributed': [133], 'equally': [134], 'to': [135, 175, 195, 205, 366], 'this': [136, 202, 312], 'work': [137], 'Correspondence:': [138], 'Li,': [140], 'email:': [141, 145], 'Xu,': [144], 'Keywords': [147], ':': [148, 156, 161, 166], 'ESCC,': [149], 'Kindlin-2,': [150], 'Myosin-9,': [151], 'three-protein': [152, 213, 262, 288, 313], 'signature,': [153], 'prognosis': [154], 'Received': [155], 'September': [157], '30,': [158], '2014': [159, 164, 169], 'Accepted': [160], 'December': [162, 167], '28,': [163], 'Published': [165], '31,': [168], 'Abstract': [170], 'Current': [171], 'staging': [172], 'is': [173, 204, 315, 333], 'inadequate': [174], 'precisely': [176], 'predict': [177], 'clinical': [178], 'outcome': [179], 'esophageal': [181, 253], 'squamous': [182], 'cell': [183], 'carcinoma': [184], '(ESCC)': [185], 'determine': [187], 'treatment': [188], 'choices,': [189], 'which': [190], 'vary': [191], 'from': [192, 265], 'operation': [193], 'alone': [194], 'intensive': [196], 'multimodal': [197], 'regimens.': [198], 'purpose': [200], 'study': [203, 343], 'investigate': [206], 'the': [207, 222, 266, 324], 'prognostic': [208, 348], 'values': [209], 'an': [211, 279, 316], 'immunohistochemistry-based': [212], 'signature': [214, 263, 289, 314], 'model': [215, 349], 'in': [216, 245, 302, 331], 'patients': [217], 'with': [218], 'ESCC.': [219], 'We': [220], 'determined': [221], 'protein': [223, 267], 'expression': [224, 286], 'Annexin': [226, 269], 'II,': [227, 270], 'cofilin': [228], '1,': [229], 'ezrin,': [230], 'fascin,': [231], 'kindlin-2,': [232, 271], 'moesin,': [233], 'MTSS1,': [234], 'myosin-9,': [235, 273], 'profilin-1,': [236], 'Rac1,': [237], 'radixin,': [238], 'ROCK2,': [239], 'talin,': [240], 'tensin': [241], 'villin': [243], 'a': [246, 345, 364], 'test': [247], 'cohort': [248, 281], 'including': [249], '110': [250], 'formalin-fixed,': [251], 'paraffin-embedded': [252], 'curative': [254], 'resection': [255], 'specimens': [256], 'by': [257, 276], 'tissue': [258], 'microarrays': [259], '(TMAs).': [260], 'A': [261], 'elicited': [264], 'cluster,': [268], 'was': [274, 290], 'validated': [275], 'TMAs': [277], 'on': [278], 'independent': [280, 317], '147': [283], 'specimens.': [284], 'highly': [291], 'predictive': [292, 325], 'ESCC': [294, 353], 'overall': [295], 'survival': [296, 300, 355], '(OS)': [297], 'disease-free': [299], '(DFS)': [301], 'both': [303], 'generation': [304], 'validation': [306], 'datasets.': [307], 'Regression': [308], 'analysis': [309], 'shows': [310], 'that': [311, 337, 350], 'predictor': [318], 'OS': [320], 'DFS.': [322], 'Furthermore,': [323], 'ability': [326], 'these': [328], 'biomarkers': [330], 'combination': [332], 'more': [334], 'robust': [335], 'than': [336], 'each': [339], 'individual': [340], 'biomarker.': [341], 'This': [342], 'demonstrates': [344], 'clinically': [346], 'applicable': [347], 'accurately': [351], 'predicts': [352], 'patient': [354], 'and/or': [356], 'tumor': [357], 'recurrence,': [358], 'thus': [360], 'could': [361], 'serve': [362], 'as': [363], 'complement': [365], 'current': [367], 'risk': [368], 'stratification': [369], 'approaches.': [370]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1841926691', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 3}], 'updated_date': '2024-09-19T18:05:15.161922', 'created_date': '2016-06-24'}