Title: Ventricular Diverticulum: A Review of the Literature
Abstract: Journal of Cardiac SurgeryVolume 28, Issue 2 p. 133-138 Review Article Ventricular Diverticulum: A Review of the Literature† Quan Li M.D., Ph.D., Corresponding Author Quan Li M.D., Ph.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaAddress for correspondence: Quan Li, M.D., Ph.D., Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, 16766 Jingshi Road, Jinan 250014, China. Fax: +86-531-82963647; e-mail: [email protected]Search for more papers by this authorHong Qu M.D., Ph.D., Hong Qu M.D., Ph.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorHaiyan Wang M.D., Haiyan Wang M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorDong Wang M.D., Dong Wang M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorPeijie Li M.D., Peijie Li M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorTianqi Liu M.D., Tianqi Liu M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this author Quan Li M.D., Ph.D., Corresponding Author Quan Li M.D., Ph.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaAddress for correspondence: Quan Li, M.D., Ph.D., Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, 16766 Jingshi Road, Jinan 250014, China. Fax: +86-531-82963647; e-mail: [email protected]Search for more papers by this authorHong Qu M.D., Ph.D., Hong Qu M.D., Ph.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorHaiyan Wang M.D., Haiyan Wang M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorDong Wang M.D., Dong Wang M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorPeijie Li M.D., Peijie Li M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this authorTianqi Liu M.D., Tianqi Liu M.D. Department of Cardiovascular Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSearch for more papers by this author First published: 13 January 2013 https://doi.org/10.1111/jocs.12059Citations: 14 †Quan Li and Hong Qu have contributed equally to this work. ‡Conflict of interest: The authors have no funding, financial relationships, or conflicts of interest to disclose. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Background: Ventricular diverticulum (VD) is a rare cardiac malformation. The surgical indications for VD remain controversial. This review is designed to determine the demographic characteristics, diagnosis, and surgical indications of this disease. Methods: Using PubMed and the Chinese electronic databases CNKI, WANFANG, and VIP, a computerized search was performed of the literature from China published between March 1965 and July 2012. Major risk factors for developing VD complications were confirmed by logistic regression analysis in case–control studies. Results: Ninety-three articles and 127 VD patients were identified in this literature review. VDs can lead to aortic insufficiency, thrombosis, infective endocarditis, heart failure, diverticular rupture, ventricular arrhythmia, and cerebral embolism. In patients with VD complications, 92.3% were men (OR = 6.43, 95% CI = 1.23–33.53), 84.6% of the patients had a fibrous type VD (OR = 10.54, 95% CI = 2.86–38.85), and 48.0% of the cases were subaortic diverticulum (SD) related (OR = 6.41, 95% CI = 1.17–35.19). Conclusions: VD can result in rupture, cerebral embolism, heart failure, ventricular arrhythmia, infective endocarditis, thrombosis and aortic insufficiency. Male gender, fibrous type, and SD are three major independent risk factors for developing VD complications. 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