Publication Information

{'id': 'https://openalex.org/W1806892368', 'doi': 'https://doi.org/10.1152/ajpendo.1998.274.4.e627', 'title': 'Melanin-concentrating hormone: a functional melanocortin antagonist in the hypothalamus', 'display_name': 'Melanin-concentrating hormone: a functional melanocortin antagonist in the hypothalamus', 'publication_year': 1998, 'publication_date': '1998-04-01', 'ids': {'openalex': 'https://openalex.org/W1806892368', 'doi': 'https://doi.org/10.1152/ajpendo.1998.274.4.e627', 'mag': '1806892368', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9575823'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajpendo.1998.274.4.e627', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S196637695', 'display_name': 'AJP Endocrinology and Metabolism', 'issn_l': '0193-1849', 'issn': ['0193-1849', '1522-1555'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084757743', 'display_name': 'David S. Ludwig', 'orcid': 'https://orcid.org/0000-0003-3307-8544'}, 'institutions': [{'id': 'https://openalex.org/I2799899409', 'display_name': 'Hadassah Medical Center', 'ror': 'https://ror.org/01cqmqj90', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799899409']}, {'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}], 'countries': ['IL', 'US'], 'is_corresponding': False, 'raw_author_name': 'David S. Ludwig', 'raw_affiliation_strings': ['Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel-Deaconess Medical Center,', 'Division of Endocrinology, Department of Medicine, Children’s Hospital, and'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel-Deaconess Medical Center,', 'institution_ids': ['https://openalex.org/I2799899409']}, {'raw_affiliation_string': 'Division of Endocrinology, Department of Medicine, Children’s Hospital, and', 'institution_ids': ['https://openalex.org/I1288882113']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019310189', 'display_name': 'Kathleen G. Mountjoy', 'orcid': 'https://orcid.org/0000-0003-1888-8207'}, 'institutions': [{'id': 'https://openalex.org/I154130895', 'display_name': 'University of Auckland', 'ror': 'https://ror.org/03b94tp07', 'country_code': 'NZ', 'type': 'education', 'lineage': ['https://openalex.org/I154130895']}], 'countries': ['NZ'], 'is_corresponding': False, 'raw_author_name': 'Kathleen G. Mountjoy', 'raw_affiliation_strings': ['Research Center for Developmental Medicine and Biology, University of Auckland, Auckland ,New Zealand'], 'affiliations': [{'raw_affiliation_string': 'Research Center for Developmental Medicine and Biology, University of Auckland, Auckland ,New Zealand', 'institution_ids': ['https://openalex.org/I154130895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066923710', 'display_name': 'Jeffrey B. Tatro', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1290900354', 'display_name': 'Tufts Medical Center', 'ror': 'https://ror.org/002hsbm82', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1290900354']}, {'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jeffrey B. Tatro', 'raw_affiliation_strings': ['Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Tupper Research Institute, Tufts University School of Medicine, New England Medical Center, Boston, Massachussetts 02111; and'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Tupper Research Institute, Tufts University School of Medicine, New England Medical Center, Boston, Massachussetts 02111; and', 'institution_ids': ['https://openalex.org/I1290900354', 'https://openalex.org/I121934306']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071126558', 'display_name': 'Jennifer A. Gillette', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1293231726', 'display_name': 'Joslin Diabetes Center', 'ror': 'https://ror.org/0280a3n32', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1293231726']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jennifer A. Gillette', 'raw_affiliation_strings': ['Elliott P. Joslin Research Laboratory, Joslin Diabetes Center, Boston 02115;'], 'affiliations': [{'raw_affiliation_string': 'Elliott P. Joslin Research Laboratory, Joslin Diabetes Center, Boston 02115;', 'institution_ids': ['https://openalex.org/I1293231726']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051174907', 'display_name': 'Robert Frederich', 'orcid': 'https://orcid.org/0000-0002-5175-3112'}, 'institutions': [{'id': 'https://openalex.org/I2799899409', 'display_name': 'Hadassah Medical Center', 'ror': 'https://ror.org/01cqmqj90', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799899409']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Robert C. Frederich', 'raw_affiliation_strings': ['Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel-Deaconess Medical Center,'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel-Deaconess Medical Center,', 'institution_ids': ['https://openalex.org/I2799899409']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017534508', 'display_name': 'Jeffrey S. Flier', 'orcid': 'https://orcid.org/0000-0001-8606-3640'}, 'institutions': [{'id': 'https://openalex.org/I2799899409', 'display_name': 'Hadassah Medical Center', 'ror': 'https://ror.org/01cqmqj90', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799899409']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Jeffrey S. Flier', 'raw_affiliation_strings': ['Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel-Deaconess Medical Center,'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel-Deaconess Medical Center,', 'institution_ids': ['https://openalex.org/I2799899409']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051918182', 'display_name': 'Eleftheria Maratos–Flier', 'orcid': 'https://orcid.org/0000-0002-5712-5643'}, 'institutions': [{'id': 'https://openalex.org/I1293231726', 'display_name': 'Joslin Diabetes Center', 'ror': 'https://ror.org/0280a3n32', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1293231726']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eleftheria Maratos-Flier', 'raw_affiliation_strings': ['Elliott P. Joslin Research Laboratory, Joslin Diabetes Center, Boston 02115;'], 'affiliations': [{'raw_affiliation_string': 'Elliott P. Joslin Research Laboratory, Joslin Diabetes Center, Boston 02115;', 'institution_ids': ['https://openalex.org/I1293231726']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.815, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 218, 'citation_normalized_percentile': {'value': 0.949482, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '274', 'issue': '4', 'first_page': 'E627', 'last_page': 'E633'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10489', 'display_name': 'Regulation of Appetite and Obesity', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10489', 'display_name': 'Regulation of Appetite and Obesity', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11584', 'display_name': 'Biochemical Analysis and Sensing Techniques', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11144', 'display_name': 'melanin and skin pigmentation', 'score': 0.9929, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/melanin-concentrating-hormone', 'display_name': 'Melanin-concentrating hormone', 'score': 0.9627709}, {'id': 'https://openalex.org/keywords/orexigenic', 'display_name': 'Orexigenic', 'score': 0.84412515}, {'id': 'https://openalex.org/keywords/melanocyte-stimulating-hormone', 'display_name': 'Melanocyte-stimulating hormone', 'score': 0.7480961}, {'id': 'https://openalex.org/keywords/hypothalamic-hormones', 'display_name': 'Hypothalamic Hormones', 'score': 0.42991593}], 'concepts': [{'id': 'https://openalex.org/C2776632733', 'wikidata': 'https://www.wikidata.org/wiki/Q3324438', 'display_name': 'Melanin-concentrating hormone', 'level': 4, 'score': 0.9627709}, {'id': 'https://openalex.org/C2777205416', 'wikidata': 'https://www.wikidata.org/wiki/Q433807', 'display_name': 'Orexigenic', 'level': 5, 'score': 0.84412515}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.8438648}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.83837533}, {'id': 'https://openalex.org/C2780989459', 'wikidata': 'https://www.wikidata.org/wiki/Q423981', 'display_name': 'Melanocyte-stimulating hormone', 'level': 3, 'score': 0.7480961}, {'id': 'https://openalex.org/C2777003273', 'wikidata': 'https://www.wikidata.org/wiki/Q164386', 'display_name': 'Hypothalamus', 'level': 2, 'score': 0.6255357}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.6011345}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.53424925}, {'id': 'https://openalex.org/C2779993316', 'wikidata': 'https://www.wikidata.org/wiki/Q6591465', 'display_name': 'Melanocortin', 'level': 3, 'score': 0.52181715}, {'id': 'https://openalex.org/C2780841215', 'wikidata': 'https://www.wikidata.org/wiki/Q422549', 'display_name': 'Glucocorticoid', 'level': 2, 'score': 0.5173394}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.44867373}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44029346}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.43057427}, {'id': 'https://openalex.org/C2908656328', 'wikidata': 'https://www.wikidata.org/wiki/Q164386', 'display_name': 'Hypothalamic Hormones', 'level': 4, 'score': 0.42991593}, {'id': 'https://openalex.org/C118303440', 'wikidata': 'https://www.wikidata.org/wiki/Q419968', 'display_name': 'Neuropeptide', 'level': 3, 'score': 0.38985547}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.1841526}, {'id': 'https://openalex.org/C93984277', 'wikidata': 'https://www.wikidata.org/wiki/Q24782073', 'display_name': 'Neuropeptide Y receptor', 'level': 4, 'score': 0.14251742}], 'mesh': [{'descriptor_ui': 'D007028', 'descriptor_name': 'Hypothalamic Hormones', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D010907', 'descriptor_name': 'Pituitary Hormones', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000521', 'descriptor_name': 'alpha-MSH', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004435', 'descriptor_name': 'Eating', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004435', 'descriptor_name': 'Eating', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007028', 'descriptor_name': 'Hypothalamic Hormones', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007028', 'descriptor_name': 'Hypothalamic Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007030', 'descriptor_name': 'Hypothalamo-Hypophyseal System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007030', 'descriptor_name': 'Hypothalamo-Hypophyseal System', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010907', 'descriptor_name': 'Pituitary Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010907', 'descriptor_name': 'Pituitary Hormones', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011919', 'descriptor_name': 'Rats, Inbred Strains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018043', 'descriptor_name': 'Receptors, Corticotropin', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D018043', 'descriptor_name': 'Receptors, Corticotropin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044101', 'descriptor_name': 'Receptors, Melanocortin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000521', 'descriptor_name': 'alpha-MSH', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000521', 'descriptor_name': 'alpha-MSH', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajpendo.1998.274.4.e627', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S196637695', 'display_name': 'AJP Endocrinology and Metabolism', 'issn_l': '0193-1849', 'issn': ['0193-1849', '1522-1555'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9575823', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1798179180', 'https://openalex.org/W1978082185', 'https://openalex.org/W1982034861', 'https://openalex.org/W1986845109', 'https://openalex.org/W1993137505', 'https://openalex.org/W1994360459', 'https://openalex.org/W1995363107', 'https://openalex.org/W1996018952', 'https://openalex.org/W1996713062', 'https://openalex.org/W2002294810', 'https://openalex.org/W2002390485', 'https://openalex.org/W2004917303', 'https://openalex.org/W2010142606', 'https://openalex.org/W2025846514', 'https://openalex.org/W2031587745', 'https://openalex.org/W2032865136', 'https://openalex.org/W2037447899', 'https://openalex.org/W2042658226', 'https://openalex.org/W2044994676', 'https://openalex.org/W2051192888', 'https://openalex.org/W2055162678', 'https://openalex.org/W2061014586', 'https://openalex.org/W2065389660', 'https://openalex.org/W2066391427', 'https://openalex.org/W2066503167', 'https://openalex.org/W2069623607', 'https://openalex.org/W2073148375', 'https://openalex.org/W2083116048', 'https://openalex.org/W2085867569', 'https://openalex.org/W2090460315', 'https://openalex.org/W2091087465', 'https://openalex.org/W2094868853', 'https://openalex.org/W2097378006', 'https://openalex.org/W2101852419', 'https://openalex.org/W2102568364', 'https://openalex.org/W2103258123', 'https://openalex.org/W2103865558', 'https://openalex.org/W2118827063', 'https://openalex.org/W2126122751', 'https://openalex.org/W2133824155', 'https://openalex.org/W2154555913', 'https://openalex.org/W2165065437', 'https://openalex.org/W2168823932', 'https://openalex.org/W2290407493', 'https://openalex.org/W632712882'], 'related_works': ['https://openalex.org/W2942049303', 'https://openalex.org/W2115874113', 'https://openalex.org/W2095318075', 'https://openalex.org/W2093965443', 'https://openalex.org/W1983244030', 'https://openalex.org/W1980514822', 'https://openalex.org/W1929193815', 'https://openalex.org/W1806892368', 'https://openalex.org/W1579647545', 'https://openalex.org/W1480031301'], 'abstract_inverted_index': {'Melanin-concentrating': [0], 'hormone': [1, 5], '(MCH)': [2], 'and': [3, 41, 56, 72, 133, 137, 143, 147], 'α-melanocyte-stimulating': [4], '(α-MSH)': [6], 'demonstrate': [7], 'opposite': [8], 'actions': [9, 84], 'on': [10, 140], 'skin': [11], 'coloration': [12], 'in': [13, 20, 46, 52, 113, 150, 162], 'teleost': [14], 'fish.': [15], 'Both': [16], 'peptides': [17], 'are': [18], 'present': [19], 'the': [21, 37, 94, 106, 117, 122, 144], 'mammalian': [22], 'brain,': [23], 'although': [24], 'their': [25], 'specific': [26], 'physiological': [27], 'roles': [28], 'remain': [29], 'largely': [30], 'unknown.': [31], 'In': [32, 66], 'this': [33], 'study,': [34], 'we': [35], 'examined': [36], 'interactions': [38], 'between': [39], 'MCH': [40, 48, 99, 132, 166], 'α-MSH': [42, 68, 103, 109, 125, 134], 'after': [43], 'intracerebroventricular': [44], 'administration': [45], 'rats.': [47], 'increased': [49, 73], 'food': [50, 70], 'intake': [51, 71], 'a': [53, 62, 78, 89, 151, 158], 'dose-dependent': [54], 'manner': [55, 153], 'lowered': [57], 'plasma': [58], 'glucocorticoid': [59, 74], 'levels': [60], 'through': [61, 157], 'mechanism': [63, 160], 'involving': [64], 'ACTH.': [65], 'contrast,': [67], 'decreased': [69], 'levels.': [75], 'MCH,': [76], 'at': [77, 88], 'twofold': [79], 'molar': [80, 91], 'excess,': [81, 92], 'antagonized': [82], 'both': [83], 'of': [85, 97, 108], 'α-MSH.': [86], 'α-MSH,': [87], 'threefold': [90], 'blocked': [93], 'orexigenic': [95], 'properties': [96], 'MCH.': [98], 'did': [100], 'not': [101], 'block': [102], 'binding': [104], 'or': [105, 119], 'ability': [107], 'to': [110, 154], 'induce': [111], 'cAMP': [112], 'cells': [114], 'expressing': [115], 'either': [116], 'MC3': [118], 'MC4': [120], 'receptor,': [121], 'principal': [123], 'brain': [124], 'receptor': [126], 'subtypes.': [127], 'These': [128], 'data': [129], 'suggest': [130], 'that': [131], 'exert': [135], 'opposing': [136], 'antagonistic': [138], 'influences': [139], 'feeding': [141], 'behavior': [142], 'stress': [145], 'response': [146], 'may': [148], 'function': [149], 'coordinate': [152], 'regulate': [155], 'metabolism': [156], 'novel': [159], 'mediated': [161], 'part': [163], 'by': [164], 'an': [165], 'receptor.': [167]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1806892368', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2025-01-11T10:39:53.605922', 'created_date': '2016-06-24'}