Publication Information

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598, 616, 642, 965, 1308, 1331], 'nonspecific': [197], 'antioxidant': [198, 1263], 'regimens': [199], 'can': [200, 888, 1132], 'inhibit': [201, 1735], 'experimental': [202, 1255], 'formation.9–14': [204], 'Although': [205, 404], 'relevance': [207], 'human': [215, 2036, 2276], 'post-angioplasty': [216, 1267], 'restenosis': [217, 1268, 1459, 2440], 'is': [218, 300, 413, 552, 709, 745, 751, 758, 800, 810, 882, 951, 1063, 1076, 1097, 1306, 1363, 2187, 2271, 2736], 'questionable,15': [219], 'well-defined': [221], 'kinetics': [222, 667], 'formation': [225, 1395, 1637, 2072], 'provide': [229], 'unique': [231], 'opportunity': [232], 'explore': [234], 'cellular': [236, 359, 1479], 'enzymatic': [238], 'sources': [239, 274], 'during': [244, 555, 2338], 'response': [251, 341, 1349, 1868], 'vivo.See': [255], 'page': [256], '21NAD(P)H': [257], 'Oxidases': [258], 'Vasculature:': [261], 'Structural': [262], 'Functional': [264], 'ConsiderationsRecent': [265], 'studies': [266], 'indicate': [267], 'nonphagocytic': [269, 355, 364], 'oxidases': [271, 292, 315, 357, 365, 1457, 2436], 'major': [273], 'wall.': [282], 'Like': [283], 'phagocytic': [285, 310, 362, 381], 'respiratory': [286], 'burst': [287], 'NADPH': [288, 311, 382, 2180, 2269, 2330, 2435, 2469, 2506, 2654, 2725], 'oxidase,': [289, 312, 383, 675], 'non-phagocytic': [290, 2099], 'reduce': [293], 'molecular': [294], 'generate': [297], 'superoxide,': [298], 'which': [299, 396, 1112, 1144], 'turn': [302], 'converted': [303], 'hydrogen': [305, 1130, 1935], 'peroxide.': [306], 'However,': [307, 992], 'unlike': [308], 'present': [316, 427, 575, 827], 'blood': [318], 'vessels': [319, 1029], 'constitutively': [321], 'active,': [322], 'producing': [323], 'relatively': [324], 'low': [325, 924], 'levels': [326, 337], 'under': [331], 'basal': [332], 'conditions': [333], 'generating': [335], 'higher': [336, 931], 'oxidants': [339, 1162, 1244, 1670], 'growth': [343, 557, 1072, 1335, 1487, 1568], 'factors': [344, 1371], 'cytokines.': [346], 'These': [347], 'attributes': [348], 'consistent': [350, 1307], 'for': [354, 1311, 1373, 1508, 1562, 1566, 1706, 2009, 2033, 2283, 2686], 'signaling.Both': [360], 'multimeric': [367], 'enzymes': [368], 'composed': [369], 'plasma': [371, 385], 'membrane': [372], 'associated-proteins': [373], 'as': [374, 376, 660, 769, 1861], 'well': [375], 'cytosolic': [377], 'factors.': [378], 'membrane-associated': [386], 'proteins': [387, 512], 'gp91phox': [388, 722, 750, 814, 1625], 'p22phox': [390, 696, 1301], 'compose': [391], 'flavocytochrome': [393], 'b558': [394], 'complex,': [395], 'forms': [397], 'catalytic': [399], 'subunit': [400, 412, 1003], 'oxidase.': [403, 437], 'known': [407], 'possess': [409], 'gp91phox,': [410, 445, 694, 1299], 'not': [414, 786, 823, 883, 956, 1907], 'highly': [415], 'expressed': [416, 753], 'cells,': [420, 488, 659, 1111, 2518, 2578], 'suggesting': [421, 506, 705], 'other': [423, 779], 'subunits': [424, 671, 1392], 'must': [425], 'be': [426, 514, 547, 889, 990, 1105, 1147, 1165, 1208, 1400], 'latter': [430], 'catalytically': [434], 'active': [435, 1758], 'Recently,': [438], 'two': [439], 'homologs': [443], 'termed': [446], 'nox1': [447, 463, 476, 500, 720, 1356, 1376, 1632], 'nox4,': [449, 505], 'were': [450, 609, 635, 649, 678, 822], 'identified': [451], 'same': [454, 1002], 'group': [455], 'investigators.6,7': [457], 'investigators': [459], 'found': [460], 'antisense': [462], 'mRNA': [464], 'inhibited': [465], 'superoxide': [469, 480, 562, 585, 608, 634, 689, 857, 905, 927, 1636, 1938], 'growth,': [472], 'whereas': [473, 930, 1324], 'overexpression': [474, 999, 1079], 'increased': [479, 855, 1707], 'proliferation.': [483], 'growth-promoting': [492], 'agonist': [493], 'angiotensin': [494, 1634, 2729], 'II': [495, 2730], 'upregulated': [496, 958], 'expression': [498, 509, 551, 669, 718, 954, 987, 1103, 1197, 1291, 1354, 1379], 'while': [501], 'downregulating': [502], 'these': [511, 1227, 1388], 'positively': [515], 'negatively': [517], 'related,': [518], 'respectively,': [519], 'growth.': [524], 'Considering': [525], 'many': [527], 'differences': [528], 'between': [529, 1219], 'grown': [533], 'culture': [535], 'versus': [536], 'those': [537], 'resident': [538], 'arterial': [541, 1084, 1482, 1768], 'wall,': [542, 640], 'however,': [543, 891, 1226], 'it': [544, 799, 1075], 'remained': [545], 'determined': [548], 'whether': [549, 1195], 'nox': [550, 1348], 'similarly': [553], 'altered': [554], 'coincident': [558], 'vivo.Localization': [564], 'Superoxide': [566], 'Production': [567], 'Nox': [569], 'Expression': [570, 691], 'Balloon-Injured': [572], 'VesselsIn': [573], 'study,': [576, 828, 832], 'Szöcs': [577, 1278, 1433, 1610], 'et': [578, 783, 994, 1125, 1279], 'al1': [579, 1280], 'examined': [580, 824], 'distribution': [583], 'balloon-injured': [588, 1028], 'fluorescent': [593], 'probe': [594], 'dihydroethidium': [595], 'conjunction': [597], 'laser': [599], 'confocal': [600], 'microscopy.': [601], 'Early': [602], 'detected': [610], 'temporally': [612], 'spatially': [614, 1366], 'co-localized': [615], 'activated': [617], 'fibroblasts.': [622, 1673], 'Late': [623], '(7': [624], 'days': [625, 701, 1119, 1154], 'or': [626, 933, 2661], 'more)': [627], 'marked': [631, 967], 'observed': [636, 1115], 'throughout': [637], 'vessel': [639], 'coinciding': [641, 964], 'maximal': [643], 'virtually': [650], 'all': [651], 'origin,': [654], 'predominately': [656], 'has': [661, 1113], 'been': [662, 1114], 'described': [663], 'previously.2By': [664], 'examining': [665], 'authors': [677], 'able': [679], 'gain': [681], 'insight': [682, 1284], 'mechanisms': [685], 'enhanced': [688, 1148, 1196], 'production.': [690], 'nox1,': [693, 1298], 'elevated': [698, 849], '3': [700], 'denudation,': [704], 'induced': [711, 936], 'vivo.': [716, 1369], 'Increased': [717], 'implicate': [723], 'both': [724, 1247], 'process.': [732], 'subsequent': [734], 'localization': [735], 'g91phox': [737], 'late': [741, 840, 960, 983, 1189, 1326], 'an': [746, 830, 886, 1014, 1965, 2138], 'interesting': [747, 945], 'observation.': [748], 'Because': [749, 1210], 'preferentially': [752], 'fibroblasts,': [755], 'one': [756], 'interpretation': [757], 'adventitial': [760, 790, 1537], 'migrated': [763], 'lamina,': [768], 'reported': [771, 900, 997, 1128], 'recently': [772, 996, 1127], 'another': [774], 'investigative': [775], 'team.4': [776], 'On': [777], 'hand,': [780], 'De': [781, 1895, 2533, 2645], 'Leon': [782, 1896, 2028], 'al16': [784], 'did': [785, 955], 'observe': [787], 'Thus,': [798, 853, 1058], 'conceivable': [801, 1077], 'subpopulation': [804], 'capable': [811], 'expressing': [813], 'injury.Although': [817], 'indices': [818], 'earlier': [831, 1046], 'index': [835], 'decreased': [836], 'phase': [841, 1190], 'only': [847], 'slightly': [848], '2': [851], 'weeks.2': [852], 'although': [854], 'occurring': [859], 'early': [860, 1302, 1701], 'likely': [864, 1065], 'stimulates': [865], 'proliferation,': [867, 929, 1323], 'process': [870, 1205], 'abates': [871], 'despite': [872], 'continued': [874], 'superoxide.': [877], 'Precisely': [878], 'how': [879], 'occurs': [881], 'known.': [884], 'Perhaps': [885], 'analogy': [887], 'drawn,': [890], 'Li': [896, 1124, 1518, 1926, 1981, 2081, 2266, 2360], 'colleagues,17': [898], 'who': [899], 'capacity': [903], 'induce': [907, 1137], 'dose-': [916], 'duration-dependent:': [918], 'single': [920], 'application': [921, 935], 'dose': [925, 1272], 'stimulated': [928], 'doses': [932], 'repeated': [934], 'cytotoxicity.Late': [937], 'Upregulation': [938, 1453, 2429], 'Nox4': [940], 'After': [941], 'Balloon': [942], 'InjuryOne': [943], 'very': [944], 'aspect': [946], 'current': [949], 'nox4': [953, 986, 1055, 1062, 1081, 1102, 1199, 1329, 1358, 1378], 'become': [957], 'until': [959], 'reduction': [968], 'rate': [971, 1008], 'proliferation.2': [976], 'causes': [978, 2102], 'consequences': [980], 'upregulation': [984, 1053, 1060, 1100, 1327], 'remain': [988, 1206, 1398], 'determined.': [991, 1209], 'Geiszt': [993, 1954], 'al18': [995], 'reduced': [1006], 'resulted': [1012], 'alteration': [1015], 'phenotype.': [1018], 'Interestingly,': [1019], 'phenotype': [1021], 'differs': [1031], 'from': [1032], 'prototypical': [1035], 'cells.19': [1039], 'Proliferation': [1040], 'reportedly': [1044], 'peaks': [1045], 'post-injury': [1049], 'phase,2': [1050], 'before': [1051], 'detected.': [1057], 'more': [1064], 'consequent': [1066], 'to,': [1067], 'rather': [1068], 'than': [1069], 'causal': [1070], 'of,': [1071], 'inhibition.': [1073], 'Nevertheless,': [1074], 'wall': [1085, 1362], 'vivo': [1087, 1530], 'could': [1088, 1104, 1236, 1337], 'attenuate': [1089], 'injury.Another': [1094], 'intriguing': [1095], 'consideration': [1096], 'pertinent': [1106], 'apoptosis': [1108, 1183, 1251, 1941, 2034], '7': [1116], '14': [1118, 1153], 'injury.20,21': [1122], 'Notably,': [1123], 'al22': [1126], 'peroxide': [1131, 1936], 'activate': [1133], 'apoptosis,': [1141], 'phenomena': [1143], 'seems': [1145], 'aorta': [1152, 1766, 1804], 'injury.19': [1157], 'This': [1158], 'finding': [1159], 'suggests': [1160], 'themselves': [1163], 'might': [1164], 'contributing': [1166], 'activation': [1168, 2514], 'Whether': [1175], 'oxidase-derived': [1177, 2181], 'contribute': [1181, 1908], 'plays': [1200, 2508], 'accumulation': [1212], 'reflects': [1216], 'balance': [1218], 'apoptotic': [1223], 'loss,': [1225], 'findings': [1228], 'administering': [1231], 'antioxidants': [1232], 'conceivably': [1237], 'limit': [1238], 'remodeling.': [1240], 'Dual': [1241], 'effects': [1242], 'stimulate': [1246], 'help': [1253], 'explain': [1254], 'clinical': [1257], 'observations': [1258], 'efficacy': [1261], 'therapy': [1264], 'ameliorate': [1266], 'depends': [1269], 'timing': [1274], 'administration.14ConclusionsIn': [1276], 'summary,': [1277], 'provided': [1282], 'new': [1283], 'regulation': [1287], 'induction': [1296, 1342], 'fibroblast': [1316], 'redox-regulation': [1320], 'coincides': [1330], 'cessation': [1332], 'play': [1338], 'apoptosis.': [1344], 'Demonstration': [1345], 'indicates': [1352], 'temporary': [1364], 'regulated': [1367], 'responsible': [1372], 'modulation': [1374], 'precise': [1385], 'contribution': [1386], 'novel': [1389], 'remodeling': [1397], 'determined.FootnotesCorrespondence': [1401], 'Weintraub,': [1405], 'MD,': [1406], 'CV': [1407], '200': [1419], 'Hawkins': [1420], 'Dr,': [1421], 'E329': [1422], 'GH,': [1423], 'City,': [1425], 'IA': [1426], '52242.': [1427], 'E-mail': [1428], '[email': [1429], 'protected]': [1430], 'References': [1431], '1': [1432, 2779], 'K,': [1434, 1558, 1611, 1649, 1722, 1820, 2063, 2254, 2499, 2605], 'Lassègue': [1435, 1581, 1606], 'B,': [1436, 1582, 1607, 2260, 2320, 2563, 2595], 'Sorescu': [1437, 1587, 1608], 'D,': [1438, 1502, 1588, 1609, 2256, 2422, 2597], 'Hilenski': [1439], 'LL,': [1440], 'Valppu': [1441], 'L,': [1442, 1788, 2246, 2262, 2603, 2708], 'Couse': [1443], 'TL,': [1444], 'Wilcox': [1445, 1902], 'JN,': 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