Title: Standardization of Diagnostic Assays for Animal Acute Phase Proteins
Abstract: This chapter discusses the standardization of diagnostic assays for animal acute phase proteins. Monitoring the plasma concentration of acute phase proteins in animals is now established as providing valuable diagnostic information in conditions involving inflammation, infection, or trauma. The investigation of these proteins is becoming even more widespread as commercial diagnostic kit producers provide veterinary laboratories with assay systems that have been validated for particular species. In addition, it has been suggested that the determination of the plasma concentration of these proteins is of particular value in farm animal production as an indicator of clinical and subclinical diseases and as an aid to meat inspection when carcasses of potential risk to public health can be identified. Development of assay methods to quantify acute phase proteins in animals has been pioneered by a number of laboratories on at least three continents. It is important for veterinary medicine that assays for each species should be as accurate as possible. International harmonization of calibration by use of a common reference preparation would be an important step toward this goal.
Publication Year: 1999
Publication Date: 1999-01-01
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 60
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