Publication Information

{'id': 'https://openalex.org/W1741544496', 'doi': 'https://doi.org/10.1111/j.1365-2249.2010.04267.x', 'title': 'The interferon-alpha and interleukin-10 responses in neonates differ from adults, and their production remains partial throughout the first 18 months of life', 'display_name': 'The interferon-alpha and interleukin-10 responses in neonates differ from adults, and their production remains partial throughout the first 18 months of life', 'publication_year': 2010, 'publication_date': '2010-10-21', 'ids': {'openalex': 'https://openalex.org/W1741544496', 'doi': 'https://doi.org/10.1111/j.1365-2249.2010.04267.x', 'mag': '1741544496', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20964643', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3026552'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2249.2010.04267.x', 'pdf_url': 'https://academic.oup.com/cei/article-pdf/162/3/494/41924806/j.1365-2249.2010.04267.x.pdf', 'source': {'id': 'https://openalex.org/S11896317', 'display_name': 'Clinical & Experimental Immunology', 'issn_l': '0009-9104', 'issn': ['0009-9104', '1365-2249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/cei/article-pdf/162/3/494/41924806/j.1365-2249.2010.04267.x.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070840474', 'display_name': 'Olivier Vosters', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1315288073', 'display_name': 'Cliniques Universitaires Saint-Luc', 'ror': 'https://ror.org/03s4khd80', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315288073']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'O Vosters', 'raw_affiliation_strings': ['Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium', 'institution_ids': ['https://openalex.org/I1315288073']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014955001', 'display_name': 'Catherine Lombard', 'orcid': 'https://orcid.org/0000-0002-5653-9545'}, 'institutions': [{'id': 'https://openalex.org/I1315288073', 'display_name': 'Cliniques Universitaires Saint-Luc', 'ror': 'https://ror.org/03s4khd80', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315288073']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'C Lombard', 'raw_affiliation_strings': ['Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium', 'institution_ids': ['https://openalex.org/I1315288073']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013591449', 'display_name': 'Floriane André', 'orcid': 'https://orcid.org/0000-0003-2900-514X'}, 'institutions': [{'id': 'https://openalex.org/I1315288073', 'display_name': 'Cliniques Universitaires Saint-Luc', 'ror': 'https://ror.org/03s4khd80', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315288073']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'F André', 'raw_affiliation_strings': ['Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium', 'institution_ids': ['https://openalex.org/I1315288073']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012085586', 'display_name': 'Gwenaëlle Sana', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1315288073', 'display_name': 'Cliniques Universitaires Saint-Luc', 'ror': 'https://ror.org/03s4khd80', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315288073']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'G Sana', 'raw_affiliation_strings': ['Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium', 'institution_ids': ['https://openalex.org/I1315288073']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038401549', 'display_name': 'Étienne Sokal', 'orcid': 'https://orcid.org/0000-0001-5597-4708'}, 'institutions': [{'id': 'https://openalex.org/I1315288073', 'display_name': 'Cliniques Universitaires Saint-Luc', 'ror': 'https://ror.org/03s4khd80', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315288073']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'E M Sokal', 'raw_affiliation_strings': ['Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium', 'institution_ids': ['https://openalex.org/I1315288073']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111481153', 'display_name': 'F. Smets', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1315288073', 'display_name': 'Cliniques Universitaires Saint-Luc', 'ror': 'https://ror.org/03s4khd80', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315288073']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'F Smets', 'raw_affiliation_strings': ['Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Université catholique de Louvain and Cliniques Universitaires Saint-Luc, Laboratory of Pediatric Hepatology and Cell Therapy, PEDI Unit, Brussels, Belgium', 'institution_ids': ['https://openalex.org/I1315288073']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2650, 'currency': 'GBP', 'value_usd': 3250, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.065, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.781546, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '162', 'issue': '3', 'first_page': '494', 'last_page': '499'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10549', 'display_name': 'Neonatal Respiratory Health Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cord-blood', 'display_name': 'Cord blood', 'score': 0.4721527}], 'concepts': [{'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.8351182}, {'id': 'https://openalex.org/C137061746', 'wikidata': 'https://www.wikidata.org/wiki/Q736033', 'display_name': 'Peripheral blood mononuclear cell', 'level': 3, 'score': 0.7435082}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.7345098}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.5668366}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.50666577}, {'id': 'https://openalex.org/C2778754761', 'wikidata': 'https://www.wikidata.org/wiki/Q421804', 'display_name': 'Lipopolysaccharide', 'level': 2, 'score': 0.47945368}, {'id': 'https://openalex.org/C2777371288', 'wikidata': 'https://www.wikidata.org/wiki/Q410130', 'display_name': 'Interleukin 2', 'level': 3, 'score': 0.47390616}, {'id': 'https://openalex.org/C2780914630', 'wikidata': 'https://www.wikidata.org/wiki/Q914952', 'display_name': 'Cord blood', 'level': 2, 'score': 0.4721527}, {'id': 'https://openalex.org/C2779341262', 'wikidata': 'https://www.wikidata.org/wiki/Q182581', 'display_name': 'Immunity', 'level': 3, 'score': 0.44513473}, {'id': 'https://openalex.org/C2776178377', 'wikidata': 'https://www.wikidata.org/wiki/Q188269', 'display_name': 'Interferon', 'level': 2, 'score': 0.44145268}, {'id': 'https://openalex.org/C2780841837', 'wikidata': 'https://www.wikidata.org/wiki/Q24741149', 'display_name': 'Interferon gamma', 'level': 3, 'score': 0.44000417}, {'id': 'https://openalex.org/C74172505', 'wikidata': 'https://www.wikidata.org/wiki/Q194908', 'display_name': 'Interleukin', 'level': 3, 'score': 0.43844798}, {'id': 'https://openalex.org/C2776955114', 'wikidata': 'https://www.wikidata.org/wiki/Q172563', 'display_name': 'Umbilical cord', 'level': 2, 'score': 0.43012702}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.055809587}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007239', 'descriptor_name': 'Infections', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D016898', 'descriptor_name': 'Interferon-alpha', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D016753', 'descriptor_name': 'Interleukin-10', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004198', 'descriptor_name': 'Disease Susceptibility', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005312', 'descriptor_name': 'Fetal Blood', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005312', 'descriptor_name': 'Fetal Blood', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007239', 'descriptor_name': 'Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016898', 'descriptor_name': 'Interferon-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016898', 'descriptor_name': 'Interferon-alpha', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016898', 'descriptor_name': 'Interferon-alpha', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016753', 'descriptor_name': 'Interleukin-10', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016753', 'descriptor_name': 'Interleukin-10', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016753', 'descriptor_name': 'Interleukin-10', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008070', 'descriptor_name': 'Lipopolysaccharides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008070', 'descriptor_name': 'Lipopolysaccharides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009838', 'descriptor_name': 'Oligodeoxyribonucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009838', 'descriptor_name': 'Oligodeoxyribonucleotides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051217', 'descriptor_name': 'Toll-Like Receptor 9', 'qualifier_ui': 'Q000819', 'qualifier_name': 'agonists', 'is_major_topic': False}, {'descriptor_ui': 'D051217', 'descriptor_name': 'Toll-Like Receptor 9', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2249.2010.04267.x', 'pdf_url': 'https://academic.oup.com/cei/article-pdf/162/3/494/41924806/j.1365-2249.2010.04267.x.pdf', 'source': {'id': 'https://openalex.org/S11896317', 'display_name': 'Clinical & Experimental Immunology', 'issn_l': '0009-9104', 'issn': ['0009-9104', '1365-2249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026552', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20964643', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2249.2010.04267.x', 'pdf_url': 'https://academic.oup.com/cei/article-pdf/162/3/494/41924806/j.1365-2249.2010.04267.x.pdf', 'source': {'id': 'https://openalex.org/S11896317', 'display_name': 'Clinical & Experimental Immunology', 'issn_l': '0009-9104', 'issn': ['0009-9104', '1365-2249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 38, 'referenced_works': ['https://openalex.org/W1554001340', 'https://openalex.org/W1578914995', 'https://openalex.org/W1593381337', 'https://openalex.org/W1661544713', 'https://openalex.org/W1723054729', 'https://openalex.org/W1967879964', 'https://openalex.org/W1968649229', 'https://openalex.org/W1971071129', 'https://openalex.org/W1978116307', 'https://openalex.org/W1984997549', 'https://openalex.org/W1999587028', 'https://openalex.org/W1999742985', 'https://openalex.org/W2001270372', 'https://openalex.org/W2005599815', 'https://openalex.org/W2006772331', 'https://openalex.org/W2015360618', 'https://openalex.org/W2019663253', 'https://openalex.org/W2022971232', 'https://openalex.org/W2028763115', 'https://openalex.org/W2030534966', 'https://openalex.org/W2033553354', 'https://openalex.org/W2035830531', 'https://openalex.org/W2039012729', 'https://openalex.org/W2052150279', 'https://openalex.org/W2064835455', 'https://openalex.org/W2069981713', 'https://openalex.org/W2071670416', 'https://openalex.org/W2089689912', 'https://openalex.org/W2091101214', 'https://openalex.org/W2102179509', 'https://openalex.org/W2104904748', 'https://openalex.org/W2114055381', 'https://openalex.org/W2118537722', 'https://openalex.org/W2139731518', 'https://openalex.org/W2154276340', 'https://openalex.org/W2157480948', 'https://openalex.org/W2167125750', 'https://openalex.org/W4243225298'], 'related_works': ['https://openalex.org/W2385563803', 'https://openalex.org/W2119122291', 'https://openalex.org/W2113148377', 'https://openalex.org/W2092766330', 'https://openalex.org/W2090281136', 'https://openalex.org/W2087976276', 'https://openalex.org/W2057173853', 'https://openalex.org/W2051111573', 'https://openalex.org/W2047541857', 'https://openalex.org/W2019578496'], 'abstract_inverted_index': {'Summary': [0], 'Previous': [1], 'studies': [2], 'have': [3, 193], 'suggested': [4], 'that': [5, 162], 'the': [6, 15, 28, 34, 42, 45, 127, 149, 153, 164, 180, 185], 'susceptibility': [7], 'of': [8, 17, 31, 33, 44, 68, 96, 132, 157, 167, 189], 'newborns': [9], 'to': [10, 14, 40, 118, 170, 179, 199, 205, 209], 'infections': [11], 'is': [12], 'linked': [13], 'immaturity': [16], 'their': [18], 'immune': [19, 35, 165, 182, 203, 213], 'system,': [20], 'but': [21, 145], 'very': [22], 'few': [23], 'data': [24], 'are': [25], 'available': [26], 'on': [27, 196], 'early': [29], 'stages': [30], 'maturation': [32], 'response.': [36], 'Therefore,': [37], 'we': [38, 120], 'decided': [39], 'investigate': [41], 'evolution': [43], 'interferon': [46], '(IFN)-α': [47], 'and': [48, 65, 71, 74, 98, 129, 208, 212], 'interleukin': [49], '(IL)-10': [50], 'responses': [51, 131, 138, 151], 'in': [52, 103, 125], 'neonatal': [53, 133], 'mononuclear': [54, 59, 134], 'cells.': [55, 135], 'To': [56], 'this': [57], 'end,': [58], 'cells': [60], 'isolated': [61], 'from': [62], 'cord': [63], 'blood': [64, 67], 'peripheral': [66], '2-,': [69], '6-': [70], '18-month-old': [72], 'children': [73], 'adults': [75], 'were': [76], 'stimulated': [77], 'with': [78], 'unmethylated': [79], 'cytosine-phosphate-guanosine': [80], 'oligodeoxynucleotide': [81], '(CpG-ODN)': [82], '2216': [83], '(IFN-α': [84], 'response)': [85, 90], 'or': [86, 111], 'lipopolysaccharide': [87], '(LPS)': [88], '(IL-10': [89], 'for': [91], '24': [92], 'h.': [93], 'The': [94], 'production': [95], 'IFN-α': [97, 128], 'IL-10': [99, 130], 'was': [100], 'then': [101], 'measured': [102], 'culture': [104], 'supernatants': [105], 'using': [106], 'enzyme-linked': [107], 'immunosorbent': [108], 'assay': [109], '(ELISA)': [110], 'a': [112, 122], '6-plex': [113], 'cytokine': [114], 'array,': [115], 'respectively.': [116], 'Compared': [117], 'adults,': [119], 'found': [121], 'significant': [123], 'impairment': [124], 'both': [126, 137], 'Interestingly,': [136], 'had': [139], 'increased': [140], 'significantly': [141], 'after': [142], '2': [143], 'months,': [144], 'remained': [146], 'lower': [147], 'than': [148], 'adult': [150, 181], 'throughout': [152, 184], 'first': [154, 186], '18': [155, 187], 'months': [156, 188], 'life.': [158, 190], 'This': [159, 191], 'study': [160], 'shows': [161], 'although': [163], 'response': [166, 183, 204], 'neonates': [168], 'tends': [169], 'mature': [171], 'fairly': [172], 'quickly,': [173], 'it': [174], 'remains': [175], 'different': [176], 'when': [177], 'compared': [178], 'could': [192], 'important': [194], 'consequences': [195], "children's": [197], 'ability': [198], 'mount': [200], 'an': [201], 'appropriate': [202], 'various': [206], 'challenges': [207], 'establish': [210], 'tolerance': [211], 'homeostasis.': [214]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1741544496', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-09T08:17:29.332724', 'created_date': '2016-06-24'}