Title: The relationship between reduced glutathione level and glutathione S-transferase activity in sheep erythrocytes.
Abstract: The relationship between reduced glutathione (GSH) level and glutathione S-transferase (GST) activity in erythrocytes was examined, using sheep erythrocytes, which have varying GSH concentrations, and dog erythrocytes with an inherited high concentration of GSH. There was a positive correlation (r = 0.529, p < 0.001) between the GSH level and GST activity in sheep erythrocytes. In dog erythrocytes, the GST activity in high-GSH cells was significantly (p < 0.001) higher than that in normal-GSH cells. These results indicate that the activity of GST in erythrocytes is directly correlated with the intracellular GSH level.
Publication Year: 1992
Publication Date: 1992-09-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 9
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