Title: Meta-analytic review of neurocognition in bipolar II disorder
Abstract: Acta Psychiatrica ScandinavicaVolume 123, Issue 3 p. 165-174 Meta-analytic review of neurocognition in bipolar II disorder E. Bora, E. Bora Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, CarltonSearch for more papers by this authorM. Yücel, M. Yücel Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton Orygen Research Centre, MelbourneSearch for more papers by this authorC. Pantelis, C. Pantelis Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, CarltonSearch for more papers by this authorM. Berk, M. Berk Orygen Research Centre, Melbourne Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, Geelong Mental Health Research Institute, Melbourne and Deakin University, Geelong, Vic., AustraliaSearch for more papers by this author E. Bora, E. Bora Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, CarltonSearch for more papers by this authorM. Yücel, M. Yücel Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton Orygen Research Centre, MelbourneSearch for more papers by this authorC. Pantelis, C. Pantelis Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, CarltonSearch for more papers by this authorM. Berk, M. Berk Orygen Research Centre, Melbourne Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, Geelong Mental Health Research Institute, Melbourne and Deakin University, Geelong, Vic., AustraliaSearch for more papers by this author First published: 24 November 2010 https://doi.org/10.1111/j.1600-0447.2010.01638.xCitations: 112 Emre Bora, Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Alan Gilbert Building NNF level 3, Carlton, Vic. 3053, Australia.E-mail: [email protected]; [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Bora E, Yücel M, Pantelis C, Berk M. Meta-analytic review of neurocognition in bipolar II disorder. Objective: The clinical distinction between bipolar II disorder (BD II) and bipolar I disorder (BD I) is not clear-cut. Cognitive functioning offers the potential to explore objective markers to help delineate this boundary. To examine this issue, we conducted a quantitative review of the cognitive profile of clinically stable patients with BD II in comparison with both patients with BD I and healthy controls. Method: Meta-analytical methods were used to compare cognitive functioning of BD II disorder with both BD I disorder and healthy controls. Results: Individuals with BD II were less impaired than those with BD I on verbal memory. There were also small but significant difference in visual memory and semantic fluency. There were no significant differences in global cognition or in other cognitive domains. Patients with BD II performed poorer than controls in all cognitive domains. Conclusion: Our findings suggest that with the exception of memory and semantic fluency, cognitive impairment in BD II is as severe as in BD I. Further studies are needed to investigate whether more severe deficits in BD I are related to neurotoxic effects of severe manic episodes on medial temporal structures or neurobiological differences from the onset of the illness. Citing Literature Volume123, Issue3March 2011Pages 165-174 RelatedInformation
Publication Year: 2010
Publication Date: 2010-11-24
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 159
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