Publication Information

{'id': 'https://openalex.org/W1692571807', 'doi': 'https://doi.org/10.1042/bj3090385', 'title': 'Evaluation of the use of the luciferase-reporter-gene system for gene-regulation studies involving cyclic AMP-elevating agents', 'display_name': 'Evaluation of the use of the luciferase-reporter-gene system for gene-regulation studies involving cyclic AMP-elevating agents', 'publication_year': 1995, 'publication_date': '1995-07-15', 'ids': {'openalex': 'https://openalex.org/W1692571807', 'doi': 'https://doi.org/10.1042/bj3090385', 'mag': '1692571807', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7626000', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1135743'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj3090385', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc1135743?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5090000768', 'display_name': 'Omar Benzakour', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'O Benzakour', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070967119', 'display_name': 'Chryso Kanthou', 'orcid': 'https://orcid.org/0000-0002-5643-4743'}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'C Kanthou', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084946111', 'display_name': 'Ulla Dennehy', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'U Dennehy', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004781522', 'display_name': 'Afrozul Haq', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'A al Haq', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111486178', 'display_name': 'Lutz-Peter Berg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'L P Berg', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108347528', 'display_name': 'V V Kakkar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'V V Kakkar', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5042443600', 'display_name': 'D.N. Cooper', 'orcid': 'https://orcid.org/0000-0002-8943-8484'}, 'institutions': [{'id': 'https://openalex.org/I4210139260', 'display_name': 'Thrombosis Research Institute', 'ror': 'https://ror.org/050r8mq79', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210139260']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'D N Cooper', 'raw_affiliation_strings': ['Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Charter Molecular Genetics Laboratory, Thrombosis Research Institute, Manresa Road, London SW3 6LR, U.K.', 'institution_ids': ['https://openalex.org/I4210139260']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.259, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.486639, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '309', 'issue': '2', 'first_page': '385', 'last_page': '387'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12561', 'display_name': 'bioluminescence and chemiluminescence research', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12561', 'display_name': 'bioluminescence and chemiluminescence research', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11663', 'display_name': 'Viral Infectious Diseases and Gene Expression in Insects', 'score': 0.9879, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10423', 'display_name': 'Neurobiology and Insect Physiology Research', 'score': 0.9866, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C111335760', 'wikidata': 'https://www.wikidata.org/wiki/Q95385166', 'display_name': 'Luciferase', 'level': 4, 'score': 0.96411204}, {'id': 'https://openalex.org/C161733203', 'wikidata': 'https://www.wikidata.org/wiki/Q911828', 'display_name': 'Reporter gene', 'level': 4, 'score': 0.8043579}, {'id': 'https://openalex.org/C2779276759', 'wikidata': 'https://www.wikidata.org/wiki/Q412747', 'display_name': 'Forskolin', 'level': 3, 'score': 0.7611489}, {'id': 'https://openalex.org/C54009773', 'wikidata': 'https://www.wikidata.org/wiki/Q1429031', 'display_name': 'Transfection', 'level': 3, 'score': 0.5718873}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.527998}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.52285343}, {'id': 'https://openalex.org/C165864922', 'wikidata': 'https://www.wikidata.org/wiki/Q411391', 'display_name': 'Regulation of gene expression', 'level': 3, 'score': 0.46189368}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.45001358}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44780198}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4438968}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40136537}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.38380325}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.280069}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.22103}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12037599}], 'mesh': [{'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017930', 'descriptor_name': 'Genes, Reporter', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015124', 'descriptor_name': '8-Bromo Cyclic Adenosine Monophosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015124', 'descriptor_name': '8-Bromo Cyclic Adenosine Monophosphate', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000527', 'descriptor_name': 'Alprostadil', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000527', 'descriptor_name': 'Alprostadil', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015500', 'descriptor_name': 'Chloramphenicol O-Acetyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015500', 'descriptor_name': 'Chloramphenicol O-Acetyltransferase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005576', 'descriptor_name': 'Colforsin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005576', 'descriptor_name': 'Colforsin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015971', 'descriptor_name': 'Gene Expression Regulation, Enzymologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009131', 'descriptor_name': 'Muscle, Smooth, Vascular', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009131', 'descriptor_name': 'Muscle, Smooth, Vascular', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D009131', 'descriptor_name': 'Muscle, Smooth, Vascular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009131', 'descriptor_name': 'Muscle, Smooth, Vascular', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj3090385', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1135743', 'pdf_url': 'https://europepmc.org/articles/pmc1135743?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1135743', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7626000', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1135743', 'pdf_url': 'https://europepmc.org/articles/pmc1135743?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1038961095', 'https://openalex.org/W1492691489', 'https://openalex.org/W1976857400', 'https://openalex.org/W1991303534', 'https://openalex.org/W1993886778', 'https://openalex.org/W1994952789', 'https://openalex.org/W2010371209', 'https://openalex.org/W2011381989', 'https://openalex.org/W2013321836', 'https://openalex.org/W2013751680', 'https://openalex.org/W2017590613', 'https://openalex.org/W2026807241', 'https://openalex.org/W2042024934', 'https://openalex.org/W2055326820', 'https://openalex.org/W2068577315', 'https://openalex.org/W2073499958', 'https://openalex.org/W2079919608', 'https://openalex.org/W2083415815', 'https://openalex.org/W2097794242', 'https://openalex.org/W2109794591', 'https://openalex.org/W2128140057', 'https://openalex.org/W2144206181', 'https://openalex.org/W2154823312', 'https://openalex.org/W2158546079', 'https://openalex.org/W4243695823', 'https://openalex.org/W4254188257'], 'related_works': ['https://openalex.org/W83646335', 'https://openalex.org/W3125147123', 'https://openalex.org/W260640041', 'https://openalex.org/W2397667500', 'https://openalex.org/W2382531667', 'https://openalex.org/W2380869999', 'https://openalex.org/W2089158163', 'https://openalex.org/W2063119860', 'https://openalex.org/W1960333619', 'https://openalex.org/W1692571807'], 'abstract_inverted_index': {'The': [0, 22], 'effects': [1], 'of': [2, 10, 24, 40, 44, 48, 61, 72, 110, 126], 'cyclic': [3], 'AMP': [4], '(cAMP)-elevating': [5], 'agents': [6, 33, 94, 137], 'on': [7, 117, 123], 'the': [8, 19, 25, 38, 59, 62, 92, 108, 124, 127], 'activity': [9, 42], 'cis-acting': [11], 'gene': [12], 'promoter': [13, 49, 64, 133], 'sequences': [14], 'are': [15], 'frequently': [16], 'studied': [17], 'using': [18], 'luciferase-reporter-gene': [20, 128], 'system.': [21], 'aim': [23], 'present': [26], 'study': [27], 'was': [28], 'to': [29], 'assess': [30], 'whether': [31], 'cAMP-elevating': [32, 93, 136], 'induce': [34], 'any': [35], 'changes': [36], 'in': [37, 69, 107, 130], 'level': [39, 109], 'luciferase': [41, 55, 111], 'independently': [43], 'a': [45, 82, 104], 'transcriptional': [46], 'activation': [47, 134], 'elements.': [50], 'Chloramphenicol': [51], 'acteyltransferase': [52], '(CAT)': [53], 'and': [54, 84, 96, 101], 'reporter': [56], 'genes': [57], 'under': [58], 'control': [60], 'same': [63], 'elements': [65], 'were': [66, 79], 'transiently': [67], 'expressed': [68], 'primary': [70], 'cultures': [71], 'human': [73], 'vascular': [74], 'smooth-muscle': [75], 'cells.': [76], 'Transfected': [77], 'cells': [78], 'treated': [80], 'with': [81, 91], 'cell-permeable': [83], 'non-hydrolysable': [85], 'cAMP': [86], 'analogue,': [87], "2'-O-monobutyryl-8-bromo": [88], 'cAMP,': [89], 'or': [90], 'forskolin': [95], 'prostaglandin': [97], 'E1': [98], '(PGE1).': [99], 'Forskolin': [100], 'PGE1': [102], 'induced': [103], 'significant': [105], 'increase': [106], 'activity,': [112], 'but': [113], 'had': [114], 'no': [115], 'effect': [116], 'CAT': [118], 'activity.': [119], 'Conclusions': [120], 'based': [121], 'solely': [122], 'use': [125], 'system': [129], 'studies': [131], 'involving': [132], 'by': [135], 'could': [138], 'therefore': [139], 'be': [140], 'misleading.': [141]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1692571807', 'counts_by_year': [], 'updated_date': '2024-12-13T15:34:37.152585', 'created_date': '2016-06-24'}