Title: The pathogenesis of Aleutian disease of mink. II. Enhancement of tissue lesions following the administration of a killed virus vaccine or passive antibody.
Abstract: Administration of an inactivated Aleutian disease virus vaccine to mink induced detectable antibody in one of 26 animals. When immunized mink were challenged with live virus, they developed more severe lesions than mink given a control vaccine. The immunized mink were also more susceptible to oral virus challenge than control mink. Passive administration of antiviral antibody at the peak of virus replication produced necrotizing acute inflammatory lesions, followed by mononuclear cell infiltrates.
Publication Year: 1972
Publication Date: 1972-07-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 69
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