Cardioprotection against ischemia/reperfusion injury by QiShenYiQi Pill&amp;reg; via ameliorate of multiple mitochondrial dysfunctions

Name: Work Video:
Duration: 3 min 30 s
Jing Rui Chen; Jing Wei; Lingyan Wang; Yan Zhu; Lan Li; Mary Akinyi; Xiumei Gao; Guan Wei Fan
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'https://openalex.org/W1505433215'], 'abstract_inverted_index': {'Cardioprotection': [0], 'against': [1, 156], 'ischemia/reperfusion': [2, 86, 243], 'injury': [3, 88, 160], 'by': [4, 131, 167, 189, 213], 'QiShenYiQi': [5, 81], 'Pill®': [6, 82], 'via': [7, 234], 'ameliorate': [8], 'of': [9, 37, 44, 48, 50, 56, 59, 65, 72, 80, 116, 186, 191, 198, 218], 'multiple': [10, 236], 'mitochondrial': [11, 93, 143, 180, 237], 'dysfunctions': [12, 238], 'Jing': [13, 16], 'Rui': [14], 'Chen,1–3': [15], 'Wei,1–3': [17], 'Ling': [18], 'Yan': [19, 21], 'Wang,1–3': [20], 'Zhu,1–3': [22], 'Lan': [23], 'Li,1–3': [24], 'Mary': [25], 'Akinyi': [26], 'Olunga,1–3': [27], 'Xiu': [28], 'Mei': [29], 'Gao,1–3': [30], 'Guan': [31], 'Wei': [32], 'Fan1–31Tianjin': [33], 'State': [34], 'Key': [35], 'Laboratory': [36, 47], 'Modern': [38], 'Chinese': [39, 52, 61, 67], 'Medicine,': [40, 62, 68], 'Tianjin,': [41, 69], "People's": [42, 70], 'Republic': [43, 71], 'China;': [45], '2Key': [46], 'Pharmacology': [49], 'Traditional': [51, 60, 66], 'Medicine': [53], 'Formulae,': [54], 'Ministry': [55], 'Education,': [57], '3Institute': [58], 'Tianjin': [63], 'University': [64], 'ChinaAim:': [73], 'To': [74], 'investigate': [75], 'the': [76, 117, 177, 196], 'potential': [77], 'cardioprotective': [78], 'effects': [79], '(QSYQ)': [83], 'on': [84], 'myocardial': [85, 158, 179], '(I/R)': [87], 'through': [89], 'antioxidative': [90], 'stress': [91, 233], 'and': [92, 95, 109, 123, 133, 145, 161, 172, 182, 193, 206, 227, 230], 'protection.Methods': [94], 'results:': [96], 'Sprague': [97, 221], 'Dawley': [98, 222], 'rats': [99, 223], 'were': [100, 129, 137, 209], 'pretreated': [101], 'with': [102, 153, 215], 'QSYQ': [103, 154, 219], 'or': [104], 'saline': [105], 'for': [106], '7': [107], 'days': [108], 'subjected': [110], 'to': [111, 139], 'ischemia': [112], '(30': [113], 'minutes': [114, 150], 'occlusion': [115], 'left': [118], 'anterior': [119], 'descending': [120], 'coronary': [121], 'artery)': [122], 'reperfusion': [124], '(120': [125], 'minutes).': [126], 'Cardiac': [127], 'functions': [128], 'evaluated': [130], 'echocardiogram': [132], 'hemodynamics.': [134], 'Myocardial': [135, 201], 'mitochondria': [136, 247], 'obtained': [138], 'evaluate': [140], 'changes': [141], 'in': [142, 195, 220], 'structure': [144, 181], 'function,': [146], 'immediately': [147], 'after': [148], '120': [149], 'reperfusion.': [151], 'Pretreatment': [152, 217], 'protected': [155], 'I/R-induced': [157], 'structural': [159], 'improved': [162], 'cardiac': [163], 'hemodynamics,': [164], 'as': [165], 'demonstrated': [166], 'normalized': [168], 'serum': [169], 'creatine': [170], 'kinase': [171], 'suppressed': [173], 'oxidative': [174, 232], 'stress.': [175], 'Moreover,': [176], 'impaired': [178], 'function': [183, 226], 'decreased': [184], 'level': [185], 'ATP': [187], '(accompanied': [188], 'reduction': [190], 'ATP5D': [192], 'increase': [194], 'expression': [197], 'cytochrome': [199], 'C).': [200], 'fiber': [202], 'rupture,': [203], 'interstitial': [204], 'edema,': [205], 'infiltrated': [207], 'leukocytes': [208], 'all': [210], 'significantly': [211], 'ameliorated': [212], 'pretreatment': [214], 'QSYQ.Conclusion:': [216], 'improves': [224], 'ventricular': [225], 'energy': [228, 245], 'metabolism': [229], 'reduces': [231], 'ameliorating': [235], 'during': [239], 'I/R': [240], 'injury.Keywords:': [241], 'QSYQ,': [242], 'injury,': [244], 'metabolism,': [246]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1648540453', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 2}], 'updated_date': '2025-01-12T02:44:10.438384', 'created_date': '2016-06-24'}
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