Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1638496459', 'doi': 'https://doi.org/10.1128/aem.64.10.4076-4078.1998', 'title': 'Balance of Activities of Alcohol Acetyltransferase and Esterase in <i>Saccharomyces cerevisiae</i> Is Important for Production of Isoamyl Acetate', 'display_name': 'Balance of Activities of Alcohol Acetyltransferase and Esterase in <i>Saccharomyces cerevisiae</i> Is Important for Production of Isoamyl Acetate', 'publication_year': 1998, 'publication_date': '1998-10-01', 'ids': {'openalex': 'https://openalex.org/W1638496459', 'doi': 'https://doi.org/10.1128/aem.64.10.4076-4078.1998', 'mag': '1638496459', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9758847', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/106606'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aem.64.10.4076-4078.1998', 'pdf_url': 'https://aem.asm.org/content/aem/64/10/4076.full.pdf', 'source': {'id': 'https://openalex.org/S158228368', 'display_name': 'Applied and Environmental Microbiology', 'issn_l': '0099-2240', 'issn': ['0099-2240', '1070-6291', '1098-5336'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://aem.asm.org/content/aem/64/10/4076.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103413488', 'display_name': 'Kiyoshi Fukuda', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kiyoshi Fukuda', 'raw_affiliation_strings': ['Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1'], 'affiliations': [{'raw_affiliation_string': 'Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057733345', 'display_name': 'N. Yamamoto', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Nagi Yamamoto', 'raw_affiliation_strings': ['Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1'], 'affiliations': [{'raw_affiliation_string': 'Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074628472', 'display_name': 'Yoshifumi Kiyokawa', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yoshifumi Kiyokawa', 'raw_affiliation_strings': ['Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1'], 'affiliations': [{'raw_affiliation_string': 'Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037592851', 'display_name': 'Toshiyasu Yanagiuchi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Toshiyasu Yanagiuchi', 'raw_affiliation_strings': ['Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1'], 'affiliations': [{'raw_affiliation_string': 'Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075286795', 'display_name': 'Yoshinori Wakai', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yoshinori Wakai', 'raw_affiliation_strings': ['Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1'], 'affiliations': [{'raw_affiliation_string': 'Kizakura Sake Brewing Co., Ltd., Fushimi-ku, Kyoto 612-8046,1', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000940493', 'display_name': 'Katsuhiko Kitamoto', 'orcid': 'https://orcid.org/0000-0002-0155-9418'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Katsuhiko Kitamoto', 'raw_affiliation_strings': ['Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032,2 and'], 'affiliations': [{'raw_affiliation_string': 'Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032,2 and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007715914', 'display_name': 'Yoshiharu Inoue', 'orcid': 'https://orcid.org/0009-0005-2166-2657'}, 'institutions': [{'id': 'https://openalex.org/I4210088032', 'display_name': 'Kyoto Bunkyo University', 'ror': 'https://ror.org/0037an472', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210088032']}, {'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshiharu Inoue', 'raw_affiliation_strings': ['Research Institute for Food Science, Kyoto University, Uji, Kyoto 611-0011,3 Japan'], 'affiliations': [{'raw_affiliation_string': 'Research Institute for Food Science, Kyoto University, Uji, Kyoto 611-0011,3 Japan', 'institution_ids': ['https://openalex.org/I4210088032', 'https://openalex.org/I22299242']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022023364', 'display_name': 'Akira Hirata', 'orcid': 'https://orcid.org/0000-0001-7279-5509'}, 'institutions': [{'id': 'https://openalex.org/I4210088032', 'display_name': 'Kyoto Bunkyo University', 'ror': 'https://ror.org/0037an472', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210088032']}, {'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akira Kimura', 'raw_affiliation_strings': ['Research Institute for Food Science, Kyoto University, Uji, Kyoto 611-0011,3 Japan'], 'affiliations': [{'raw_affiliation_string': 'Research Institute for Food Science, Kyoto University, Uji, Kyoto 611-0011,3 Japan', 'institution_ids': ['https://openalex.org/I4210088032', 'https://openalex.org/I22299242']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.123, 'has_fulltext': False, 'cited_by_count': 124, 'citation_normalized_percentile': {'value': 0.905172, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '64', 'issue': '10', 'first_page': '4076', 'last_page': '4078'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10932', 'display_name': 'Metabolic Engineering and Synthetic Biology', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10932', 'display_name': 'Metabolic Engineering and Synthetic Biology', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10171', 'display_name': 'Technologies for Biofuel Production from Biomass', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10497', 'display_name': 'Genomic Expression and Function in Yeast Organism', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/isoamyl-acetate', 'display_name': 'Isoamyl acetate', 'score': 0.9849556}, {'id': 'https://openalex.org/keywords/isoamyl-alcohol', 'display_name': 'Isoamyl alcohol', 'score': 0.9565816}, {'id': 'https://openalex.org/keywords/esterase', 'display_name': 'Esterase', 'score': 0.7508351}, {'id': 'https://openalex.org/keywords/enzymatic-hydrolysis', 'display_name': 'Enzymatic Hydrolysis', 'score': 0.439668}, {'id': 'https://openalex.org/keywords/ethyl-hexanoate', 'display_name': 'Ethyl hexanoate', 'score': 0.42913568}], 'concepts': [{'id': 'https://openalex.org/C2776061406', 'wikidata': 'https://www.wikidata.org/wiki/Q221307', 'display_name': 'Isoamyl acetate', 'level': 3, 'score': 0.9849556}, {'id': 'https://openalex.org/C2776452521', 'wikidata': 'https://www.wikidata.org/wiki/Q223101', 'display_name': 'Isoamyl alcohol', 'level': 3, 'score': 0.9565816}, {'id': 'https://openalex.org/C2777261171', 'wikidata': 'https://www.wikidata.org/wiki/Q418750', 'display_name': 'Esterase', 'level': 3, 'score': 0.7508351}, {'id': 'https://openalex.org/C2779222958', 'wikidata': 'https://www.wikidata.org/wiki/Q45422', 'display_name': 'Yeast', 'level': 2, 'score': 0.6419982}, {'id': 'https://openalex.org/C39699697', 'wikidata': 'https://www.wikidata.org/wiki/Q869095', 'display_name': 'Brewing', 'level': 3, 'score': 0.63492095}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6197068}, {'id': 'https://openalex.org/C100544194', 'wikidata': 'https://www.wikidata.org/wiki/Q41760', 'display_name': 'Fermentation', 'level': 2, 'score': 0.61411244}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.58955646}, {'id': 'https://openalex.org/C2777576037', 'wikidata': 'https://www.wikidata.org/wiki/Q719725', 'display_name': 'Saccharomyces cerevisiae', 'level': 3, 'score': 0.58848226}, {'id': 'https://openalex.org/C94412978', 'wikidata': 'https://www.wikidata.org/wiki/Q103135', 'display_name': 'Hydrolysis', 'level': 2, 'score': 0.4436103}, {'id': 'https://openalex.org/C2781066024', 'wikidata': 'https://www.wikidata.org/wiki/Q156', 'display_name': 'Alcohol', 'level': 2, 'score': 0.43492296}, {'id': 'https://openalex.org/C2780377148', 'wikidata': 'https://www.wikidata.org/wiki/Q905406', 'display_name': 'Ethyl hexanoate', 'level': 3, 'score': 0.42913568}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.41091394}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.38308987}, {'id': 'https://openalex.org/C2779858419', 'wikidata': 'https://www.wikidata.org/wiki/Q407153', 'display_name': 'Ethyl acetate', 'level': 2, 'score': 0.21287835}], 'mesh': [{'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002265', 'descriptor_name': 'Carboxylic Ester Hydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000439', 'descriptor_name': 'Pentanols', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001709', 'descriptor_name': 'Biotechnology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001709', 'descriptor_name': 'Biotechnology', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D002265', 'descriptor_name': 'Carboxylic Ester Hydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002265', 'descriptor_name': 'Carboxylic Ester Hydrolases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003470', 'descriptor_name': 'Culture Media', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005421', 'descriptor_name': 'Flavoring Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000439', 'descriptor_name': 'Pentanols', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D000439', 'descriptor_name': 'Pentanols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014920', 'descriptor_name': 'Wine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aem.64.10.4076-4078.1998', 'pdf_url': 'https://aem.asm.org/content/aem/64/10/4076.full.pdf', 'source': {'id': 'https://openalex.org/S158228368', 'display_name': 'Applied and Environmental Microbiology', 'issn_l': '0099-2240', 'issn': ['0099-2240', '1070-6291', '1098-5336'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc106606', 'pdf_url': 'https://europepmc.org/articles/pmc106606?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106606', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9758847', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aem.64.10.4076-4078.1998', 'pdf_url': 'https://aem.asm.org/content/aem/64/10/4076.full.pdf', 'source': {'id': 'https://openalex.org/S158228368', 'display_name': 'Applied and Environmental Microbiology', 'issn_l': '0099-2240', 'issn': ['0099-2240', '1070-6291', '1098-5336'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W1726545745', 'https://openalex.org/W1775749144', 'https://openalex.org/W1969220831', 'https://openalex.org/W1971812168', 'https://openalex.org/W1973782344', 'https://openalex.org/W1979939548', 'https://openalex.org/W1989829065', 'https://openalex.org/W1993319523', 'https://openalex.org/W2020813437', 'https://openalex.org/W2020862954', 'https://openalex.org/W2026642300', 'https://openalex.org/W2045907910', 'https://openalex.org/W2050732471', 'https://openalex.org/W2054555891', 'https://openalex.org/W2055643996', 'https://openalex.org/W2065926860', 'https://openalex.org/W2075590600', 'https://openalex.org/W2083996638', 'https://openalex.org/W2084003566', 'https://openalex.org/W2312419500', 'https://openalex.org/W2315565816', 'https://openalex.org/W2318608760', 'https://openalex.org/W2436194278', 'https://openalex.org/W2474452409', 'https://openalex.org/W2947319071', 'https://openalex.org/W4240553853', 'https://openalex.org/W4245289693', 'https://openalex.org/W4253339019', 'https://openalex.org/W4256575365'], 'related_works': ['https://openalex.org/W2897649138', 'https://openalex.org/W2412016392', 'https://openalex.org/W2376742188', 'https://openalex.org/W2366180254', 'https://openalex.org/W2353910756', 'https://openalex.org/W2317556115', 'https://openalex.org/W2312716194', 'https://openalex.org/W2110573326', 'https://openalex.org/W2094861213', 'https://openalex.org/W1070426703'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Isoamyl': [1], 'acetate': [2, 44, 103, 131], 'is': [3, 20, 127], 'synthesized': [4], 'from': [5], 'isoamyl': [6, 43, 70, 102, 130], 'alcohol': [7, 13], 'and': [8, 19, 68, 77], 'acetyl': [9], 'coenzyme': [10], 'A': [11], 'by': [12, 22], 'acetyltransferase': [14], '(AATFase)': [15], 'in': [16, 45, 81, 104, 133], 'Saccharomyces': [17], 'cerevisiae': [18], 'hydrolyzed': [21], 'esterases': [23], 'at': [24], 'the': [25, 31, 62, 69, 92, 99, 105, 120], 'same': [26], 'time.': [27], 'We': [28], 'hypothesized': [29], 'that': [30, 119], 'balance': [32, 121], 'of': [33, 42, 59, 61, 91, 101, 112, 122], 'both': [34], 'enzyme': [35, 125], 'activities': [36, 126], 'was': [37], 'important': [38, 128], 'for': [39, 129], 'optimum': [40], 'production': [41], 'sake': [46, 83, 94, 106, 134], 'brewing.': [47, 84], 'To': [48], 'test': [49], 'this': [50], 'hypothesis,': [51], 'we': [52, 117], 'constructed': [53], 'yeast': [54], 'strains': [55, 80], 'with': [56, 108], 'different': [57], 'numbers': [58], 'copies': [60], 'AATFase': [63], 'gene': [64, 73], '(': [65, 74], 'ATF1': [66], ')': [67, 76], 'acetate-hydrolyzing': [71], 'esterase': [72, 114], 'IAH1': [75], 'used': [78], 'these': [79, 123], 'small-scale': [82], 'Fermentation': [85], 'profiles': [86], 'as': [87, 89], 'well': [88], 'components': [90], 'resulting': [93], 'were': [95], 'largely': [96], 'alike;': [97], 'however,': [98], 'amount': [100], 'increased': [107], 'an': [109], 'increasing': [110], 'ratio': [111], 'AATFase/Iah1p': [113], 'activity.': [115], 'Therefore,': [116], 'conclude': [118], 'two': [124], 'accumulation': [132], 'mash.': [135]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1638496459', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-09-16T21:27:25.670798', 'created_date': '2016-06-24'}