Title: Laboratory Correlates of Protection against <i>Haemophilus influenzae</i> Type b Disease
Abstract: Annals of the New York Academy of SciencesVolume 754, Issue 1 p. 278-288 Laboratory Correlates of Protection against Haemophilus influenzae Type b Disease Importance of Assessment of Antibody Avidity and Immunologic Memorya DAN M. GRANOFF, Corresponding Author DAN M. GRANOFF Children's Hospital Oakland Research Institute 747 52nd Street Oakland, California 94609To whom correspondence should be addressed.Search for more papers by this authorALEXANDER H. LUCAS, ALEXANDER H. LUCAS Children's Hospital Oakland Research Institute 747 52nd Street Oakland, California 94609Search for more papers by this author DAN M. GRANOFF, Corresponding Author DAN M. GRANOFF Children's Hospital Oakland Research Institute 747 52nd Street Oakland, California 94609To whom correspondence should be addressed.Search for more papers by this authorALEXANDER H. LUCAS, ALEXANDER H. LUCAS Children's Hospital Oakland Research Institute 747 52nd Street Oakland, California 94609Search for more papers by this author First published: May 1995 https://doi.org/10.1111/j.1749-6632.1995.tb44461.xCitations: 41 a Supported by United States Public Health Service Grants AI17962, AI21842, AI25008, and AI08851 from the National Institutes of Health. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Käyhty, H., H. Peltola, V. Karanko & P. H. Mäkelä. 1983. The protective level of serum antibodies to the capsular polysaccharide of Haemophilus influenzae type b. J. Infect. Dis. 147: 1100. 2 Peltola, H., H. Käyhty, M. Virtanen & P. H. Mäkelä. 1984. Prevention of Haemophilus influenzae type b bacteremic infections with the capsular polysaccharide vaccine. N. Engl. J. Med. 310: 1566–1569. 3 Santosham, M., R. Reid, D. M. Ambrosino et al. 1987. Prevention of Haemophilus influenzae type b infections in high risk infants with bacterial polysaccharide immune globulin. N. Engl. J. Med. 317: 923–929. 4 Robbins, J. B., J. C. Parke, Jr., R. Schneerson & J. K. Whisnant 1973. Quantitative measurements of "natural" and immunization induced Haemophilus influenzae type b capsular antibodies. Pediatr. Res. 7: 103–110. 5 Ambrosino, D. M., J. R. Schreiber, R. S. Daum & G. R. Siber 1983. Efficacy of human hyperimmune globulin in prevention of Haemophilus influenzae type b disease in infant rats. Infect. Immun. 39: 709–714. 6 Anderson, P. 1984. The protective level of serum antibodies to the capsular polysaccharide of Haemophilus influenzae type b. J. Infect. Dis. 149: 1034. 7 Amir, J., X. Liang & D. M. Granoff 1990. Variability in the functional activity of vaccineinduced antibody to Haemophilus influenzae type b. Pediatr. Res. 27: 358–364. 8 Schlesinger, J., D. M. Granoff & The Vaccine Study Group 1992. Avidity and bactericidal activity of antibody elicited by different Haemophilus influenzae type b conjugate vaccines. JAMA 267: 1489–1494. 9 Eskola, J., H. Käyhty, S. K. Takala et al. 1990. A randomized, prospective field trial of a conjugate vaccine in the protection of infants and young children against invasive Haemophilus influenzae type disease. N. Engl. J. Med. 323: 1393–1400. 10 Granoff, D. M., S. J. Holmes, M. T. Osterholm, J. E. McHugh, A. H. Lucas, E. L. Anderson, R. B. Belshe, J. L. Jacobs, F. Medley & T. V. Murphy 1993. Induction of immunologic memory in infants primed with Haemophilus influenzae type b conjugate vaccines. J. Infect. Dis. 168: 663–671. 11 Granoff, D. M., P. G. Shackelford, S. J. Holmes, The Collaborative Vaccine Study Group & A. H. Lucas 1993. Variable region expression in the antibody responses of vaccinated infants with Haemophilus influenzae type b polysaccharide-protein conjugates: Description of a new γ light chain-associated idiotype and relation between idiotype expression, avidity, and vaccine formulation. J. Clin. Invest. 91: 788–796. 12 Granoff, D. M., P. G. Shackelford, J. P. Pandey & E. G. Boies 1986. Antibody responses to Haemophilus influenzae type b polysaccharide in relation to the Km(1) and G2(m)23 immunoglobulin allotypes. J. Infect. Dis. 154: 257–264. 13 Shackelford, P. G., D. M. Granoff, S. J. Nelson, M. G. Scott, D. S. Smith & M. H. Nahm 1987. Subclass distribution of human antibodies to Haemophilus influenzae type b capsular polysaccharide. J. Immunol. 138: 587–592. 14 Griswold, W. R., A. H. Lucas, J. F. Bastian & G. Garcia 1989. Functional affinity of antibody to the Haemophilus influenzae type b polysaccharide. J. Infect. Dis. 159: 1084–1087. 15 Anderson, P., R. A. Insel, S. Porcelli & J. I. Ward 1987. Immunochemical variables affecting radioantigen-binding assays of antibody to Haemophilus influenzae type b capsular polysaccharide in children's sera. J. Infect. Dis. 156: 582–590. 16 Steward, M. W. & A. M. Lew 1985. The importance of antibody affinity in the performance of immunoassays for antibody. J. Immunol. Methods 78: 173–190. 17 Karush, F. 1976. Multivalent binding and functional affinity. In Contemporary Topics in Molecular Immunology, Vol. 5. F. P. Inman, Ed.: 217. Plenum Press. New York , NY . 18 Lucas, A. H. & D. M. Granoff 1990. A major cross-reactive idiotype associated with human antibodies to the Haemophilus influenzae b polysaccharide. J. Clin. Invest. 85: 1158–1166. 19 Lucas, A. H., R. J. Langley, D. M. Granoff, M. H. Nahm, M. Y. Kitamura & M. G. Scott 1991. An idiotypic marker associated with a germ-line encoded x light chain variable region that predominates the human antibody response to the Haemophilus influenzae b capsular polysaccharide. J. Clin. Invest. 88: 1811–1818. 20 Santosham, M., M. Wolff, R. Reid et al. 1991. The efficacy in Navajo infants of a conjugate vaccine consisting of Haemophilus influenzae type b polysaccharide and Neisseria meningitidis outer-membrane protein complex. N. Engl. J. Med. 324: 1767–1772. 21 Hall, C. B., D. M. Granoff, D. S. Gromisch et al. & Committee on Infectious Diseases. 1993. Haemophilus influenzae type b conjugate vaccines: Recommendations for immunization with recently and previously licensed vaccines. Pediatrics 92: 480–488. 22 Anderson, P., M. Pichichero, M. Edwards, C. R. Porch & R. Insel 1987. Priming and induction of Haemophilus influenzae type b capsular antibodies in early infancy by Dpo20, an oligosaccharide-protein conjugate vaccine. J. Pediatr. 111: 644–650. 23 Weinberg, G. A., M. S. Einhorn, A. A. Lenoir, P. D. Granoff & D. M. Granoff 1987. Immunologic priming to capsular polysaccharide in infants immunized with Haemophilus influenzae type b polysaccharide-Naesseria meningitidis outer membrane protein conjugate vaccine. J., Pediatr. 111: 22–27. 24 Käyhty, H., J. Eskola, H. Peltola, L. Saarinen & P. H. Mäkelä. 1992. High antibody responses to booster doses of either Haemophilus influenzae capsular polysaccharide or conjugate vaccine after primary immunization with conjugate vaccines. J. Infect. Dis. 165: S165–S166. 25 Granoff, D. M. & R. S. Munson 1986. Prospects for prevention of Haemophilus influenzae type b disease by immunization. J. Infect. Dis. 153: 448–461. 26 Granoff, D. M., E. L. Anderson, M. T. Osterholm, S. J. Holmes, R. B. Belshe, F. Medley & T. V. Murphy 1992. Differences in the immunogenicity of three Haemophilus influenzae type b conjugate vaccines in infants. J. Pediatr. 121: 187–194. 27 Murphy, T. V., K. E. White, P. Pastor et al. 1993. Declining incidence of Haemophilus influenzae type b disease since introduction of vaccination. JAMA 269: 246–248. 28 Holmes, S. J., M. T. Osterholm, D. M. Granoff & The Vaccine Failure Group 1992. Haemophilus influenzae type disease in infants vaccinated with Hib conjugate vaccine at >12 months. Presented at 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy. Anaheim, California, October 11–14, 1992. 29 Lucas, A. H. & D. M. Granoff 1995. Functional differences in idiotypically-defined IgGl anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type b polysaccharide-protein conjugates. J. Immunol. In press. Citing Literature Volume754, Issue1Combined Vaccines and Simultaneous Administration: Current Issues and PerspectivesMay 1995Pages 278-288 ReferencesRelatedInformation
Publication Year: 1995
Publication Date: 1995-05-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 57
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot