Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1608118493', 'doi': 'https://doi.org/10.1002/dvg.22844', 'title': 'Early development of the neural plate: New roles for apoptosis and for one of its main effectors caspase‐3', 'display_name': 'Early development of the neural plate: New roles for apoptosis and for one of its main effectors caspase‐3', 'publication_year': 2015, 'publication_date': '2015-01-24', 'ids': {'openalex': 'https://openalex.org/W1608118493', 'doi': 'https://doi.org/10.1002/dvg.22844', 'mag': '1608118493', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25619400'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/dvg.22844', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S124648948', 'display_name': 'genesis', 'issn_l': '1526-954X', 'issn': ['1526-954X', '1526-968X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://hal.science/hal-02561075/document', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076256704', 'display_name': 'Hugo Juraver-Geslin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hugo A. Juraver‐Geslin', 'raw_affiliation_strings': ['Department of Basic Science, Craniofacial Biology, College of Dentistry, New York University New York, New York'], 'affiliations': [{'raw_affiliation_string': 'Department of Basic Science, Craniofacial Biology, College of Dentistry, New York University New York, New York', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5014708503', 'display_name': 'Béatrice Durand', 'orcid': 'https://orcid.org/0000-0002-0047-288X'}, 'institutions': [{'id': 'https://openalex.org/I80043', 'display_name': 'Institut Curie', 'ror': 'https://ror.org/04t0gwh46', 'country_code': 'FR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I80043']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Béatrice C. Durand', 'raw_affiliation_strings': ['CNRS UMR3347, Centre Universitaire, Batiment 110, F-91 405 Orsay cedex, France', 'INSERM U1021 Centre Universitaire Batiment 110 F‐91 405 Orsay cedex France', 'INSERM U1021, Centre Universitaire, Batiment 110, F-91 405 Orsay cedex, France', 'Institut Curie, Centre Universitaire, Batiment 110, F-91 405 Orsay cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Institut Curie, Centre Universitaire, Batiment 110, F-91 405 Orsay cedex, France', 'institution_ids': ['https://openalex.org/I80043']}, {'raw_affiliation_string': 'CNRS UMR3347, Centre Universitaire, Batiment 110, F-91 405 Orsay cedex, France', 'institution_ids': ['https://openalex.org/I1294671590']}, {'raw_affiliation_string': 'INSERM U1021 Centre Universitaire Batiment 110 F‐91 405 Orsay cedex France', 'institution_ids': ['https://openalex.org/I154526488']}, {'raw_affiliation_string': 'INSERM U1021, Centre Universitaire, Batiment 110, F-91 405 Orsay cedex, France', 'institution_ids': ['https://openalex.org/I154526488']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5014708503'], 'corresponding_institution_ids': ['https://openalex.org/I80043', 'https://openalex.org/I1294671590', 'https://openalex.org/I154526488'], 'apc_list': {'value': 3450, 'currency': 'USD', 'value_usd': 3450, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.019, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 60, 'citation_normalized_percentile': {'value': 0.999741, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '53', 'issue': '2', 'first_page': '203', 'last_page': '224'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9931, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9931, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12009', 'display_name': 'Hedgehog Signaling Pathway Studies', 'score': 0.993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12065', 'display_name': 'Hippo pathway signaling and YAP/TAZ', 'score': 0.9832, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/neuroepithelial-cell', 'display_name': 'Neuroepithelial cell', 'score': 0.761168}, {'id': 'https://openalex.org/keywords/neural-development', 'display_name': 'Neural Development', 'score': 0.6240286}, {'id': 'https://openalex.org/keywords/progenitor', 'display_name': 'Progenitor', 'score': 0.53842723}, {'id': 'https://openalex.org/keywords/neuroblast', 'display_name': 'Neuroblast', 'score': 0.48693407}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7749249}, {'id': 'https://openalex.org/C200707615', 'wikidata': 'https://www.wikidata.org/wiki/Q13652744', 'display_name': 'Neuroepithelial cell', 'level': 4, 'score': 0.761168}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6576024}, {'id': 'https://openalex.org/C201750760', 'wikidata': 'https://www.wikidata.org/wiki/Q1896218', 'display_name': 'Progenitor cell', 'level': 3, 'score': 0.64082944}, {'id': 'https://openalex.org/C136834591', 'wikidata': 'https://www.wikidata.org/wiki/Q2944097', 'display_name': 'Neural stem cell', 'level': 3, 'score': 0.627725}, {'id': 'https://openalex.org/C461258', 'wikidata': 'https://www.wikidata.org/wiki/Q1345738', 'display_name': 'Neural development', 'level': 3, 'score': 0.6240286}, {'id': 'https://openalex.org/C2776637008', 'wikidata': 'https://www.wikidata.org/wiki/Q14860072', 'display_name': 'Sonic hedgehog', 'level': 3, 'score': 0.57804}, {'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.5691489}, {'id': 'https://openalex.org/C15729860', 'wikidata': 'https://www.wikidata.org/wiki/Q2329919', 'display_name': 'Progenitor', 'level': 4, 'score': 0.53842723}, {'id': 'https://openalex.org/C4746552', 'wikidata': 'https://www.wikidata.org/wiki/Q1456827', 'display_name': 'Neurogenesis', 'level': 2, 'score': 0.52099496}, {'id': 'https://openalex.org/C51785407', 'wikidata': 'https://www.wikidata.org/wiki/Q2627568', 'display_name': 'Effector', 'level': 2, 'score': 0.5206182}, {'id': 'https://openalex.org/C197849852', 'wikidata': 'https://www.wikidata.org/wiki/Q2314823', 'display_name': 'Neural plate', 'level': 4, 'score': 0.50783855}, {'id': 'https://openalex.org/C39961270', 'wikidata': 'https://www.wikidata.org/wiki/Q2927095', 'display_name': 'Neuroblast', 'level': 3, 'score': 0.48693407}, {'id': 'https://openalex.org/C121587040', 'wikidata': 'https://www.wikidata.org/wiki/Q898769', 'display_name': 'Homeobox', 'level': 4, 'score': 0.47088844}, {'id': 'https://openalex.org/C2778944004', 'wikidata': 'https://www.wikidata.org/wiki/Q91703', 'display_name': 'Caenorhabditis elegans', 'level': 3, 'score': 0.43640906}, {'id': 'https://openalex.org/C126749454', 'wikidata': 'https://www.wikidata.org/wiki/Q1348455', 'display_name': 'Neural crest', 'level': 3, 'score': 0.42695147}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.40333986}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.39958167}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.3810547}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.17543402}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.16292596}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08997375}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.06451109}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D053148', 'descriptor_name': 'Caspase 3', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D054258', 'descriptor_name': 'Neural Plate', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053148', 'descriptor_name': 'Caspase 3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047908', 'descriptor_name': 'Intracellular Signaling Peptides and Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047908', 'descriptor_name': 'Intracellular Signaling Peptides and Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D054258', 'descriptor_name': 'Neural Plate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054258', 'descriptor_name': 'Neural Plate', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D054258', 'descriptor_name': 'Neural Plate', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/dvg.22844', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S124648948', 'display_name': 'genesis', 'issn_l': '1526-954X', 'issn': ['1526-954X', '1526-968X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hal.science/hal-02561075', 'pdf_url': 'https://hal.science/hal-02561075/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-02561075/file/Genesis%202015%20Juraver-Geslin.pdf', 'pdf_url': 'https://hal.archives-ouvertes.fr/hal-02561075/file/Genesis%202015%20Juraver-Geslin.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hal.science/hal-02561075/file/Genesis%202015%20Juraver-Geslin.pdf', 'pdf_url': 'https://hal.science/hal-02561075/file/Genesis%202015%20Juraver-Geslin.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-02561075/document', 'pdf_url': 'https://hal.archives-ouvertes.fr/hal-02561075/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25619400', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://hal.science/hal-02561075', 'pdf_url': 'https://hal.science/hal-02561075/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320309749', 'funder_display_name': 'Association pour la Recherche sur le Cancer', 'award_id': '5115'}], 'datasets': [], 'versions': [], 'referenced_works_count': 174, 'referenced_works': ['https://openalex.org/W125412302', 'https://openalex.org/W14483127', 'https://openalex.org/W1481472040', 'https://openalex.org/W1484503455', 'https://openalex.org/W1490480018', 'https://openalex.org/W1533376056', 'https://openalex.org/W1596939807', 'https://openalex.org/W1606017150', 'https://openalex.org/W1609339746', 'https://openalex.org/W1621302266', 'https://openalex.org/W1892599478', 'https://openalex.org/W1922106993', 'https://openalex.org/W1955467086', 'https://openalex.org/W1966492450', 'https://openalex.org/W1971939303', 'https://openalex.org/W1972856100', 'https://openalex.org/W1975035795', 'https://openalex.org/W1975419284', 'https://openalex.org/W1975439181', 'https://openalex.org/W1975845564', 'https://openalex.org/W1976754131', 'https://openalex.org/W1977238166', 'https://openalex.org/W1977707442', 'https://openalex.org/W1978297707', 'https://openalex.org/W1979414180', 'https://openalex.org/W1980272463', 'https://openalex.org/W1981552778', 'https://openalex.org/W1983132229', 'https://openalex.org/W1983391688', 'https://openalex.org/W1983477032', 'https://openalex.org/W1986340187', 'https://openalex.org/W1987785848', 'https://openalex.org/W1989194294', 'https://openalex.org/W1989585885', 'https://openalex.org/W1990832657', 'https://openalex.org/W1991626630', 'https://openalex.org/W1992089991', 'https://openalex.org/W1993145412', 'https://openalex.org/W1993302385', 'https://openalex.org/W1993736057', 'https://openalex.org/W1993759302', 'https://openalex.org/W1994323820', 'https://openalex.org/W1994662145', 'https://openalex.org/W1996484852', 'https://openalex.org/W1996709598', 'https://openalex.org/W1996973708', 'https://openalex.org/W1998041465', 'https://openalex.org/W2000283379', 'https://openalex.org/W2000599605', 'https://openalex.org/W2000735073', 'https://openalex.org/W2000894919', 'https://openalex.org/W2000992130', 'https://openalex.org/W2002404925', 'https://openalex.org/W2003731518', 'https://openalex.org/W2003903011', 'https://openalex.org/W2006419043', 'https://openalex.org/W2007468095', 'https://openalex.org/W2008197152', 'https://openalex.org/W2010132676', 'https://openalex.org/W2012543502', 'https://openalex.org/W2014479208', 'https://openalex.org/W2015964634', 'https://openalex.org/W2016558382', 'https://openalex.org/W2017097723', 'https://openalex.org/W2017938741', 'https://openalex.org/W2018456985', 'https://openalex.org/W2019122545', 'https://openalex.org/W2019625059', 'https://openalex.org/W2019827294', 'https://openalex.org/W2022133633', 'https://openalex.org/W2022863392', 'https://openalex.org/W2024313116', 'https://openalex.org/W2027234236', 'https://openalex.org/W2027309763', 'https://openalex.org/W2029503587', 'https://openalex.org/W2029643611', 'https://openalex.org/W2030381529', 'https://openalex.org/W2031319416', 'https://openalex.org/W2032713647', 'https://openalex.org/W2033234356', 'https://openalex.org/W2033291406', 'https://openalex.org/W2033420737', 'https://openalex.org/W2033828028', 'https://openalex.org/W2036762610', 'https://openalex.org/W2039493143', 'https://openalex.org/W2041665011', 'https://openalex.org/W2042141743', 'https://openalex.org/W2042772659', 'https://openalex.org/W2044091203', 'https://openalex.org/W2045308252', 'https://openalex.org/W2045562635', 'https://openalex.org/W2045843159', 'https://openalex.org/W2046437105', 'https://openalex.org/W2046798922', 'https://openalex.org/W2049110705', 'https://openalex.org/W2049350180', 'https://openalex.org/W2050939520', 'https://openalex.org/W2051237104', 'https://openalex.org/W2054196675', 'https://openalex.org/W2054463240', 'https://openalex.org/W2054657634', 'https://openalex.org/W2054832698', 'https://openalex.org/W2055763811', 'https://openalex.org/W2057375692', 'https://openalex.org/W2059614045', 'https://openalex.org/W2064792767', 'https://openalex.org/W2066832607', 'https://openalex.org/W2067263369', 'https://openalex.org/W2067570858', 'https://openalex.org/W2067924946', 'https://openalex.org/W2069720145', 'https://openalex.org/W2071497196', 'https://openalex.org/W2072325944', 'https://openalex.org/W2072335762', 'https://openalex.org/W2074054430', 'https://openalex.org/W2076014943', 'https://openalex.org/W2076721314', 'https://openalex.org/W2077099727', 'https://openalex.org/W2077249171', 'https://openalex.org/W2077521933', 'https://openalex.org/W2078408136', 'https://openalex.org/W2081235375', 'https://openalex.org/W2081518960', 'https://openalex.org/W2083404062', 'https://openalex.org/W2086031504', 'https://openalex.org/W2086127889', 'https://openalex.org/W2086669296', 'https://openalex.org/W2088354566', 'https://openalex.org/W2089020494', 'https://openalex.org/W2094105022', 'https://openalex.org/W2096823486', 'https://openalex.org/W2102319846', 'https://openalex.org/W2106133121', 'https://openalex.org/W2107031745', 'https://openalex.org/W2109955944', 'https://openalex.org/W2110825275', 'https://openalex.org/W2110838173', 'https://openalex.org/W2111197864', 'https://openalex.org/W2115261304', 'https://openalex.org/W2115438940', 'https://openalex.org/W2115837318', 'https://openalex.org/W2121780827', 'https://openalex.org/W2123637914', 'https://openalex.org/W2126622935', 'https://openalex.org/W2127111407', 'https://openalex.org/W2128975512', 'https://openalex.org/W2130446433', 'https://openalex.org/W2131233061', 'https://openalex.org/W2135470166', 'https://openalex.org/W2136930579', 'https://openalex.org/W2139043462', 'https://openalex.org/W2141694824', 'https://openalex.org/W2144642481', 'https://openalex.org/W2147648210', 'https://openalex.org/W2148294117', 'https://openalex.org/W2151676539', 'https://openalex.org/W2151907359', 'https://openalex.org/W2156125640', 'https://openalex.org/W2157754274', 'https://openalex.org/W2162581376', 'https://openalex.org/W2164574344', 'https://openalex.org/W2164650328', 'https://openalex.org/W2165874498', 'https://openalex.org/W2168553061', 'https://openalex.org/W2170847633', 'https://openalex.org/W2184947876', 'https://openalex.org/W2185961847', 'https://openalex.org/W2186043758', 'https://openalex.org/W2186576445', 'https://openalex.org/W2352023541', 'https://openalex.org/W2411458346', 'https://openalex.org/W4239718055', 'https://openalex.org/W4243347737', 'https://openalex.org/W74337203'], 'related_works': ['https://openalex.org/W2974883981', 'https://openalex.org/W2892311734', 'https://openalex.org/W2741508056', 'https://openalex.org/W2498822467', 'https://openalex.org/W2410215370', 'https://openalex.org/W2153893639', 'https://openalex.org/W2048521888', 'https://openalex.org/W2031054146', 'https://openalex.org/W1993888492', 'https://openalex.org/W185558933'], 'abstract_inverted_index': {'Summary': [0], 'Despite': [1], 'its': [2, 65], 'tremendous': [3], 'complexity,': [4], 'the': [5, 17, 24, 48, 71, 76, 82, 90, 140, 146, 150, 153, 159, 161, 165], 'vertebrate': [6], 'nervous': [7], 'system': [8], 'emerges': [9], 'from': [10], 'a': [11, 34, 51, 127], 'homogenous': [12], 'layer': [13], 'of': [14, 29, 50, 62, 64, 75, 89, 126, 145, 152], 'neuroepithelial': [15], 'cells,': [16], 'neural': [18, 132, 154, 172], 'plate.': [19, 155], 'Its': [20], 'formation': [21], 'relies': [22], 'on': [23, 158], 'time‐': [25], 'and': [26, 40, 44, 58, 73, 84, 111, 121, 142, 164, 168, 175], 'space‐controlled': [27], 'progression': [28], 'developmental': [30], 'programs.': [31], 'Apoptosis': [32, 57], 'is': [33, 45, 79], 'biological': [35], 'process': [36], 'that': [37, 114, 130], 'removes': [38], 'superfluous': [39], 'potentially': [41], 'dangerous': [42], 'cells': [43], 'implemented': [46], 'through': [47], 'activation': [49], 'molecular': [52], 'pathway': [53], 'conserved': [54], 'during': [55, 93], 'evolution.': [56], 'an': [59], 'unconventional': [60], 'function': [61, 129], 'one': [63], 'main': [66], 'effectors,': [67], 'caspase‐3,': [68], 'contribute': [69], 'to': [70], 'patterning': [72], 'growth': [74], 'neuroepithelium.': [77], 'Little': [78], 'known': [80], 'about': [81], 'intrinsic': [83], 'extrinsic': [85], 'cues': [86], 'controlling': [87], 'activities': [88, 170], 'apoptotic': [91, 147], 'machinery': [92, 148], 'development.': [94], 'The': [95, 103], 'BarH‐like': [96], '(Barhl)': [97], 'proteins': [98, 116], 'are': [99], 'homeodomain‐containing': [100], 'transcription': [101], 'factors.': [102], 'observations': [104], 'in': [105, 118, 149, 171], 'Caenorhabditis': [106], 'elegans': [107], ',': [108, 110], 'Xenopus': [109], 'mice': [112], 'document': [113], 'Barhl': [115], 'act': [117], 'cell': [119, 123], 'survival': [120, 174], 'as': [122], 'type‐specific': [124], 'regulators': [125], 'caspase‐3': [128], 'limits': [131], 'progenitor': [133, 173], 'proliferation.': [134, 176], 'In': [135], 'this': [136], 'review,': [137], 'we': [138], 'discuss': [139], 'roles': [141], 'regulatory': [143], 'modes': [144], 'development': [151], 'We': [156], 'focus': [157], 'Barhl2,': [160], 'Sonic': [162], 'Hedgehog,': [163], 'Wnt': [166], 'pathways': [167], 'their': [169], 'genesis': [177], '53:203–224,': [178], '2015.': [179], '©': [180], '2015': [181], 'Wiley': [182], 'Periodicals,': [183], 'Inc.': [184]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1608118493', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-12-15T05:14:14.702701', 'created_date': '2016-06-24'}