Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1607813664', 'doi': 'https://doi.org/10.1002/14651858.cd003709.pub2', 'title': 'Vasopressors for shock', 'display_name': 'Vasopressors for shock', 'publication_year': 2004, 'publication_date': '2004-07-19', 'ids': {'openalex': 'https://openalex.org/W1607813664', 'doi': 'https://doi.org/10.1002/14651858.cd003709.pub2', 'mag': '1607813664', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15266497'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/14651858.cd003709.pub2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S71429176', 'display_name': 'Cochrane database of systematic reviews', 'issn_l': '1361-6137', 'issn': ['1361-6137', '1469-493X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319727', 'host_organization_name': 'Cochrane', 'host_organization_lineage': ['https://openalex.org/P4310319727'], 'host_organization_lineage_names': ['Cochrane'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'reference-entry', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5030282743', 'display_name': 'Marcus Müllner', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76134821', 'display_name': 'Medical University of Vienna', 'ror': 'https://ror.org/05n3x4p02', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I76134821']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Marcus Müllner', 'raw_affiliation_strings': ['#N##TAB##TAB##TAB##TAB# Medical University of Vienna#N##TAB##TAB##TAB#'], 'affiliations': [{'raw_affiliation_string': '#N##TAB##TAB##TAB##TAB# Medical University of Vienna#N##TAB##TAB##TAB#', 'institution_ids': ['https://openalex.org/I76134821']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105937519', 'display_name': 'Bernhard Urbanek', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802328216', 'display_name': 'Vienna General Hospital', 'ror': 'https://ror.org/05f0zr486', 'country_code': 'AT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802328216']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Bernhard Urbanek', 'raw_affiliation_strings': ['Vienna General Hospital'], 'affiliations': [{'raw_affiliation_string': 'Vienna General Hospital', 'institution_ids': ['https://openalex.org/I2802328216']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113931211', 'display_name': 'Christof Havel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76134821', 'display_name': 'Medical University of Vienna', 'ror': 'https://ror.org/05n3x4p02', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I76134821']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Christof Havel', 'raw_affiliation_strings': ['University of Vienna, Medical Faculty'], 'affiliations': [{'raw_affiliation_string': 'University of Vienna, Medical Faculty', 'institution_ids': ['https://openalex.org/I76134821']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071782546', 'display_name': 'Heidrun Losert', 'orcid': 'https://orcid.org/0000-0003-1951-2682'}, 'institutions': [{'id': 'https://openalex.org/I76134821', 'display_name': 'Medical University of Vienna', 'ror': 'https://ror.org/05n3x4p02', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I76134821']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Heidrun Losert', 'raw_affiliation_strings': ['University of Vienna, Medical Faculty'], 'affiliations': [{'raw_affiliation_string': 'University of Vienna, Medical Faculty', 'institution_ids': ['https://openalex.org/I76134821']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044273994', 'display_name': 'Gunnar Gamper', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I129774422', 'display_name': 'University of Vienna', 'ror': 'https://ror.org/03prydq77', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I129774422']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Gunnar Gamper', 'raw_affiliation_strings': ['Univ. of Vienna#TAB#'], 'affiliations': [{'raw_affiliation_string': 'Univ. of Vienna#TAB#', 'institution_ids': ['https://openalex.org/I129774422']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5037228297', 'display_name': 'Harald Herkner', 'orcid': 'https://orcid.org/0000-0003-1329-6149'}, 'institutions': [{'id': 'https://openalex.org/I76134821', 'display_name': 'Medical University of Vienna', 'ror': 'https://ror.org/05n3x4p02', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I76134821']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Harald Herkner', 'raw_affiliation_strings': ['Medical University of Vienna'], 'affiliations': [{'raw_affiliation_string': 'Medical University of Vienna', 'institution_ids': ['https://openalex.org/I76134821']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.238, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 151, 'citation_normalized_percentile': {'value': 0.863343, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10218', 'display_name': 'Sepsis Diagnosis and Treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10218', 'display_name': 'Sepsis Diagnosis and Treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11700', 'display_name': 'Hemodynamic Monitoring and Therapy', 'score': 0.9918, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10645', 'display_name': 'Cardiac Arrest and Resuscitation', 'score': 0.9898, 'subfield': {'id': 'https://openalex.org/subfields/2711', 'display_name': 'Emergency Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dobutamine', 'display_name': 'Dobutamine', 'score': 0.49234283}, {'id': 'https://openalex.org/keywords/cinahl', 'display_name': 'CINAHL', 'score': 0.48985407}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.81948215}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.63081485}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.5685578}, {'id': 'https://openalex.org/C95190672', 'wikidata': 'https://www.wikidata.org/wiki/Q815382', 'display_name': 'Meta-analysis', 'level': 2, 'score': 0.5546926}, {'id': 'https://openalex.org/C2779473830', 'wikidata': 'https://www.wikidata.org/wiki/Q1540899', 'display_name': 'MEDLINE', 'level': 2, 'score': 0.53419656}, {'id': 'https://openalex.org/C2781185063', 'wikidata': 'https://www.wikidata.org/wiki/Q422782', 'display_name': 'Dobutamine', 'level': 3, 'score': 0.49234283}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.49038482}, {'id': 'https://openalex.org/C2781145037', 'wikidata': 'https://www.wikidata.org/wiki/Q5011772', 'display_name': 'CINAHL', 'level': 3, 'score': 0.48985407}, {'id': 'https://openalex.org/C2776376669', 'wikidata': 'https://www.wikidata.org/wiki/Q5094647', 'display_name': 'Intensive care unit', 'level': 2, 'score': 0.46608967}, {'id': 'https://openalex.org/C2781300812', 'wikidata': 'https://www.wikidata.org/wiki/Q178061', 'display_name': 'Shock (circulatory)', 'level': 2, 'score': 0.45761412}, {'id': 'https://openalex.org/C194828623', 'wikidata': 'https://www.wikidata.org/wiki/Q2861470', 'display_name': 'Emergency medicine', 'level': 1, 'score': 0.35603637}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.3088702}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2221367}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.12194139}, {'id': 'https://openalex.org/C27415008', 'wikidata': 'https://www.wikidata.org/wiki/Q7256382', 'display_name': 'Psychological intervention', 'level': 2, 'score': 0.11183745}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.10815793}, {'id': 'https://openalex.org/C178853913', 'wikidata': 'https://www.wikidata.org/wiki/Q1642137', 'display_name': 'Hemodynamics', 'level': 2, 'score': 0.088223875}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C17744445', 'wikidata': 'https://www.wikidata.org/wiki/Q36442', 'display_name': 'Political science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199539241', 'wikidata': 'https://www.wikidata.org/wiki/Q7748', 'display_name': 'Law', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D012769', 'descriptor_name': 'Shock', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D014662', 'descriptor_name': 'Vasoconstrictor Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016032', 'descriptor_name': 'Randomized Controlled Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012769', 'descriptor_name': 'Shock', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012772', 'descriptor_name': 'Shock, Septic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012772', 'descriptor_name': 'Shock, Septic', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D014662', 'descriptor_name': 'Vasoconstrictor Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/14651858.cd003709.pub2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S71429176', 'display_name': 'Cochrane database of systematic reviews', 'issn_l': '1361-6137', 'issn': ['1361-6137', '1469-493X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319727', 'host_organization_name': 'Cochrane', 'host_organization_lineage': ['https://openalex.org/P4310319727'], 'host_organization_lineage_names': ['Cochrane'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15266497', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.87}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1971144920', 'https://openalex.org/W1977478388', 'https://openalex.org/W1992216549', 'https://openalex.org/W1993685612', 'https://openalex.org/W2003947509', 'https://openalex.org/W2004411303', 'https://openalex.org/W2014982458', 'https://openalex.org/W2015222304', 'https://openalex.org/W2028546766', 'https://openalex.org/W2054331417', 'https://openalex.org/W2068973347', 'https://openalex.org/W2069431723', 'https://openalex.org/W2070111146', 'https://openalex.org/W2088783942', 'https://openalex.org/W2102372841', 'https://openalex.org/W2118560222', 'https://openalex.org/W2128855592', 'https://openalex.org/W2135595177', 'https://openalex.org/W2142960568', 'https://openalex.org/W2148668313', 'https://openalex.org/W2157657037', 'https://openalex.org/W2157823046', 'https://openalex.org/W2160691650', 'https://openalex.org/W2164292141', 'https://openalex.org/W2324829729', 'https://openalex.org/W2397706596', 'https://openalex.org/W2409547353', 'https://openalex.org/W2460793324', 'https://openalex.org/W2599527603', 'https://openalex.org/W2993155701', 'https://openalex.org/W4239528954', 'https://openalex.org/W4241388752', 'https://openalex.org/W4321596906'], 'related_works': ['https://openalex.org/W4285005768', 'https://openalex.org/W322030742', 'https://openalex.org/W3144336631', 'https://openalex.org/W2438917488', 'https://openalex.org/W2388274277', 'https://openalex.org/W2076813506', 'https://openalex.org/W2075251017', 'https://openalex.org/W2057736164', 'https://openalex.org/W2030875469', 'https://openalex.org/W1859326399'], 'abstract_inverted_index': {'Background': [0], 'Besides': [1], 'reversing': [2], 'the': [3, 6, 11, 17, 51, 60, 69, 98, 108, 122, 150, 177, 188, 248, 254, 370], 'underlying': [4], 'cause,': [5], 'first': [7], 'line': [8], 'treatment': [9, 52, 61, 178, 371], 'for': [10, 50, 59, 73, 141, 155, 176, 217, 234], 'symptoms': [12], 'of': [13, 19, 47, 53, 56, 62, 71, 100, 115, 126, 179, 182, 230, 274, 373], 'shock': [14, 57, 63, 75, 269, 293, 312], 'is': [15, 25, 40, 44, 348, 364], 'usually': [16], 'administration': [18], 'intravenous': [20, 174], 'fluids.': [21], 'If': [22], 'this': [23], 'method': [24], 'not': [26, 237, 349], 'successful,': [27], 'vasopressors': [28, 72, 88, 168, 172], 'such': [29, 104], 'as': [30, 105], 'dopamine,': [31], 'dobutamine,': [32], 'adrenaline,': [33], 'noradrenaline': [34], 'and': [35, 112, 134, 152, 193, 206, 245], 'vasopressin': [36, 305], 'are': [37], 'recommended.': [38], 'It': [39], 'unclear': [41], 'if': [42], 'there': [43, 336], 'a': [45, 209, 361], 'vasopressor': [46, 101, 363], 'choice,': [48], 'either': [49], 'particular': [54, 87, 362], 'forms': [55], 'or': [58, 171], 'in': [64, 76, 107, 149, 265, 289, 308, 327, 369], 'general.': [65], 'Objectives': [66], 'To': [67], 'assess': [68, 85], 'efficacy': [70], 'circulatory': [74, 183], 'critically': [77], 'ill': [78], 'patients.': [79], 'Our': [80], 'main': [81, 189], 'aim': [82], 'was': [83, 187, 204, 233, 251], 'to': [84, 95, 138, 253, 281, 300, 319, 351, 358, 366], 'whether': [86, 97, 360], 'reduce': [89], 'overall': [90], 'mortality.': [91], 'We': [92, 119, 145, 160, 212, 223, 355], 'also': [93, 146], 'intended': [94], 'identify': [96], 'choice': [99], 'influences': [102], 'outcomes': [103], 'length‐of‐stay': [106], 'intensive': [109], 'care': [110], 'unit': [111], 'health‐related': [113], 'quality': [114], 'life.': [116], 'Search': [117], 'methods': [118], 'searched': [120, 153], 'MEDLINE,': [121], 'Cochrane': [123], 'Central': [124], 'Register': [125], 'Controlled': [127], 'Trials,': [128], 'EMBASE,': [129], 'PASCAL': [130], 'BioMed,': [131], 'CINAHL,': [132], 'BIOSIS,': [133], 'PsychINFO:all': [135], 'from': [136], 'inception': [137], 'November': [139], '2003;': [140], 'randomized': [142, 162, 226], 'controlled': [143, 163, 227], 'trials.': [144, 157, 228], 'asked': [147], 'experts': [148], 'field': [151], 'meta‐registries': [154], 'ongoing': [156], 'Selection': [158], 'criteria': [159], 'included': [161], 'trials': [164], 'comparing': [165], 'various': [166], 'vasopressors,': [167], 'with': [169, 173, 208, 262, 267, 287, 291, 306, 310, 325, 329], 'placebo': [170, 307], 'fluids': [175], 'any': [180], 'kind': [181], 'failure': [184], '(shock).': [185], 'Mortality': [186], 'outcome.': [190], 'Data': [191], 'collection': [192], 'analysis': [194], 'Two': [195, 256, 302], 'reviewers': [196, 203], 'abstracted': [197], 'data': [198], 'independently.': [199], 'Disagreement': [200], 'between': [201], 'two': [202, 240, 246], 'discussed': [205], 'resolved': [207], 'third': [210], 'reviewer.': [211], 'used': [213], 'random': [214], 'effects': [215], 'models': [216], 'combining': [218], 'quantitative': [219], 'data.': [220], 'Main': [221], 'results': [222], 'identified': [224], 'eight': [225], 'Reporting': [229], 'methodological': [231], 'details': [232], 'many': [235], 'items': [236], 'satisfactory:': [238], 'only': [239], 'studies': [241, 257, 284, 303], 'reported': [242], 'allocation': [243], 'concealment,': [244], 'that': [247], 'outcome': [249], 'assessor': [250], 'blind': [252], 'intervention.': [255], 'compared': [258, 285, 304, 323], 'norepinephrine': [259, 286, 326], 'plus': [260], 'dobutamine': [261], 'epinephrine': [263], 'alone': [264], 'patients': [266, 290, 309, 328], 'septic': [268, 292, 311], '(52': [270], 'patients,': [271, 295, 314], 'relative': [272, 296, 315], 'risk': [273, 297, 316], 'death': [275], '0.98,': [276], '95%': [277], 'confidence': [278], 'interval': [279], '0.57': [280, 299], '1.67).': [282], 'Three': [283], 'dopamine': [288], '(62': [294], '0.88,': [298], '1.36).': [301], '(58': [313], '1.04,': [317], '0.06': [318], '19.33).': [320], 'One': [321], 'study': [322], 'terlipressin': [324], 'refractory': [330], 'hypotension': [331], 'after': [332], 'general': [333], 'anaesthesia': [334], 'but': [335], 'were': [337, 356], 'no': [338], 'deaths': [339], '(20': [340], 'patients).': [341], "Authors'": [342], 'conclusions': [343], 'The': [344], 'current': [345], 'available': [346], 'evidence': [347], 'suited': [350], 'inform': [352], 'clinical': [353], 'practice.': [354], 'unable': [357], 'determine': [359], 'superior': [365], 'other': [367], 'agents': [368], 'ofstates': [372], 'shock.': [374]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1607813664', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-10T04:15:35.864256', 'created_date': '2016-06-24'}