Publication Information

{'id': 'https://openalex.org/W1593328756', 'doi': 'https://doi.org/10.1159/000327326', 'title': 'Acute Kidney Injury Biomarkers and Endpoints for Clinical Trials', 'display_name': 'Acute Kidney Injury Biomarkers and Endpoints for Clinical Trials', 'publication_year': 2011, 'publication_date': '2011-01-01', 'ids': {'openalex': 'https://openalex.org/W1593328756', 'doi': 'https://doi.org/10.1159/000327326', 'mag': '1593328756', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21625113'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000327326', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S38631682', 'display_name': 'Contributions to nephrology', 'issn_l': '0302-5144', 'issn': ['0302-5144', '1662-2782'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5086691656', 'display_name': 'Patrick Murray', 'orcid': 'https://orcid.org/0000-0001-8516-1839'}, 'institutions': [], 'countries': ['IE'], 'is_corresponding': True, 'raw_author_name': 'Patrick T. Murray', 'raw_affiliation_strings': ['UCD Catherine Mc Auley Education and Research Centre, Dublin, Ireland.'], 'affiliations': [{'raw_affiliation_string': 'UCD Catherine Mc Auley Education and Research Centre, Dublin, Ireland.', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5086691656'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.117, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.247821, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': None, 'issue': None, 'first_page': '208', 'last_page': '212'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10684', 'display_name': 'Acute Kidney Injury Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10684', 'display_name': 'Acute Kidney Injury Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10408', 'display_name': 'Chronic Kidney Disease and Diabetes', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11116', 'display_name': 'Trauma, Hemostasis, Coagulopathy, Resuscitation', 'score': 0.9762, 'subfield': {'id': 'https://openalex.org/subfields/2706', 'display_name': 'Critical Care and Intensive Care Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/clinical-research', 'display_name': 'Clinical Research', 'score': 0.42302456}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.93300486}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.7934575}, {'id': 'https://openalex.org/C2780472472', 'wikidata': 'https://www.wikidata.org/wiki/Q424337', 'display_name': 'Acute kidney injury', 'level': 2, 'score': 0.77074564}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.7694677}, {'id': 'https://openalex.org/C22467394', 'wikidata': 'https://www.wikidata.org/wiki/Q849359', 'display_name': 'Multidisciplinary approach', 'level': 2, 'score': 0.4551818}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.42452195}, {'id': 'https://openalex.org/C502991105', 'wikidata': 'https://www.wikidata.org/wiki/Q5133849', 'display_name': 'Clinical research', 'level': 2, 'score': 0.42302456}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.22385672}, {'id': 'https://openalex.org/C36289849', 'wikidata': 'https://www.wikidata.org/wiki/Q34749', 'display_name': 'Social science', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C144024400', 'wikidata': 'https://www.wikidata.org/wiki/Q21201', 'display_name': 'Sociology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D058186', 'descriptor_name': 'Acute Kidney Injury', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D058186', 'descriptor_name': 'Acute Kidney Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003404', 'descriptor_name': 'Creatinine', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D003404', 'descriptor_name': 'Creatinine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000327326', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S38631682', 'display_name': 'Contributions to nephrology', 'issn_l': '0302-5144', 'issn': ['0302-5144', '1662-2782'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21625113', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.8, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1489794536', 'https://openalex.org/W1967300023', 'https://openalex.org/W1973013098', 'https://openalex.org/W1980228387', 'https://openalex.org/W1983062811', 'https://openalex.org/W2000347404', 'https://openalex.org/W2001032948', 'https://openalex.org/W2020689357', 'https://openalex.org/W2043106562', 'https://openalex.org/W2058350585', 'https://openalex.org/W2095573004', 'https://openalex.org/W2103260117', 'https://openalex.org/W2104305817', 'https://openalex.org/W2109531898', 'https://openalex.org/W2109983971', 'https://openalex.org/W2116909658', 'https://openalex.org/W2119585617', 'https://openalex.org/W2129967807', 'https://openalex.org/W2139937737', 'https://openalex.org/W2143262001', 'https://openalex.org/W2145711589', 'https://openalex.org/W2148409083', 'https://openalex.org/W2158659030', 'https://openalex.org/W2159578467', 'https://openalex.org/W2160054854', 'https://openalex.org/W2160530471', 'https://openalex.org/W2170433159', 'https://openalex.org/W91108901'], 'related_works': ['https://openalex.org/W4230698529', 'https://openalex.org/W3182450353', 'https://openalex.org/W2923890311', 'https://openalex.org/W2898992494', 'https://openalex.org/W2803854770', 'https://openalex.org/W2461838604', 'https://openalex.org/W2412528326', 'https://openalex.org/W2332746628', 'https://openalex.org/W2157531023', 'https://openalex.org/W2115848393'], 'abstract_inverted_index': {'Acute': [0], 'kidney': [1, 99], 'injury': [2], '(AKI)': [3], 'is': [4, 67], 'associated': [5], 'with': [6, 87], 'a': [7, 64], 'heavy': [8], 'burden': [9], 'of': [10, 22, 34, 40, 57, 72, 91, 98, 113, 120], 'morbidity': [11], 'and': [12, 19, 38, 43, 80, 94, 118], 'mortality,': [13], 'despite': [14], 'advances': [15], 'in': [16, 53, 60, 82], 'intensive': [17], 'care': [18], 'the': [20, 32, 55, 73, 88, 116], 'management': [21], 'high-risk': [23], 'patients.': [24], 'Numerous': [25], 'clinical': [26, 58, 74, 111, 123], 'trials': [27, 59, 112], 'have': [28], 'failed': [29], 'to': [30, 77, 104, 108], 'ameliorate': [31], 'outcomes': [33], 'AKI.': [35], 'The': [36], 'proposal': [37], 'validation': [39], 'standardized': [41], 'definitions': [42], 'staging': [44], 'criteria': [45], 'for': [46, 115], 'AKI': [47, 83], 'has': [48], 'been': [49], 'an': [50], 'important': [51], 'step': [52], 'improving': [54], 'conduct': [56, 109], 'this': [61, 121], 'population.': [62], 'Similarly,': [63], 'multidisciplinary': [65], 'dialogue': [66], 'making': [68], 'progress': [69], 'towards': [70], 'standardization': [71], 'trial': [75], 'endpoints': [76], 'prove': [78], 'efficacy': [79], 'effectiveness': [81], 'research.': [84], 'Taken': [85], 'together': [86], 'increasing': [89], 'availability': [90], 'timely,': [92], 'sensitive,': [93], 'specific': [95], 'novel': [96], 'biomarkers': [97], 'damage,': [100], 'we': [101], 'are': [102], 'poised': [103], 'use': [105], 'these': [106], 'tools': [107], 'successful': [110], 'agents': [114], 'prevention': [117], 'treatment': [119], 'devastating': [122], 'syndrome.': [124]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1593328756', 'counts_by_year': [{'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-17T01:39:48.227714', 'created_date': '2016-06-24'}