Title: Discovery and Development of Aliskiren, the First‐in‐Class Direct Renin Inhibitor for the Treatment of Hypertension
Abstract: This chapter contains sections titled: Introduction The History of Renin and Aliskiren The Renin–Angiotensin–Aldosterone System History of the Renin Inhibitor Project in Ciba–Geigy/Novartis New Concept Toward (P3–P1) Topological Peptidomimetic Inhibitors Early Preclinical Leads Scalable Synthesis Development of Aliskiren Properties of Aliskiren Clinical Efficacy of Aliskiren Conclusions and Outlook References
Publication Year: 2010
Publication Date: 2010-08-25
Language: en
Type: other
Indexed In: ['crossref']
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Cited By Count: 3
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