Title: Does Exposure to Influenza Very Early in Life Affect Mortality Risk during a Subsequent Outbreak? The 1890 and 1918 Pandemics in Canada
Abstract: Two major pandemics of infectious disease include: the 1890 Russian influenza pandemic and the 1918 Spanish pandemic. The lack of attention given to both pandemics may have influenced the theorizing about the stages and progression of the epidemiologic transition. This chapter presents the results of preliminary research into the age distribution of deaths among young adults during the 1918 pandemic. It uses the Developmental Origins of Health and Disease Hypothesis (DOHaD) and concepts of scarring during critical periods of development and original antigenic sin to explain why individuals at this particular age were at heightened risk. The Russian and Spanish influenza pandemics are similar in that they are both described as completely global and reliant on rapid trade and transit for their almost instantaneous spread. Yet, there are two major differences between the 1890 and 1918 pandemics: the case-fatality rate and the age structure of mortality.
Publication Year: 2014
Publication Date: 2014-03-14
Language: en
Type: other
Indexed In: ['crossref']
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Cited By Count: 8
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