Publication Information

{'id': 'https://openalex.org/W1587126988', 'doi': None, 'title': 'SNARE assembly and regulation on membranes', 'display_name': 'SNARE assembly and regulation on membranes', 'publication_year': 2006, 'publication_date': '2006-08-01', 'ids': {'openalex': 'https://openalex.org/W1587126988', 'mag': '1587126988'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://ediss.uni-goettingen.de/bitstream/11858/00-1735-0000-0006-B5F0-D/1/siddiqui.pdf', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'dissertation', 'type_crossref': 'dissertation', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5078346198', 'display_name': 'Tabrez J. Siddiqui', 'orcid': 'https://orcid.org/0000-0002-6938-7827'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Tabrez Jamal Siddiqui', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5078346198'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 61}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10407', 'display_name': 'Lipid Membrane Structure and Behavior', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/synaptobrevin', 'display_name': 'Synaptobrevin', 'score': 0.92640066}, {'id': 'https://openalex.org/keywords/snap25', 'display_name': 'SNAP25', 'score': 0.90420055}, {'id': 'https://openalex.org/keywords/snare-complex', 'display_name': 'SNARE complex', 'score': 0.82718277}, {'id': 'https://openalex.org/keywords/vesicle-fusion', 'display_name': 'Vesicle fusion', 'score': 0.72699594}, {'id': 'https://openalex.org/keywords/stx1a', 'display_name': 'STX1A', 'score': 0.53817457}, {'id': 'https://openalex.org/keywords/kiss-and-run-fusion', 'display_name': 'Kiss-and-run fusion', 'score': 0.45790076}], 'concepts': [{'id': 'https://openalex.org/C2777029164', 'wikidata': 'https://www.wikidata.org/wiki/Q82452579', 'display_name': 'Synaptobrevin', 'level': 5, 'score': 0.92640066}, {'id': 'https://openalex.org/C134499376', 'wikidata': 'https://www.wikidata.org/wiki/Q14897641', 'display_name': 'SNAP25', 'level': 5, 'score': 0.90420055}, {'id': 'https://openalex.org/C2908790754', 'wikidata': 'https://www.wikidata.org/wiki/Q279694', 'display_name': 'SNARE complex', 'level': 4, 'score': 0.82718277}, {'id': 'https://openalex.org/C196330066', 'wikidata': 'https://www.wikidata.org/wiki/Q7923216', 'display_name': 'Vesicle fusion', 'level': 5, 'score': 0.72699594}, {'id': 'https://openalex.org/C148785051', 'wikidata': 'https://www.wikidata.org/wiki/Q671136', 'display_name': 'Synaptic vesicle', 'level': 4, 'score': 0.7125647}, {'id': 'https://openalex.org/C53728453', 'wikidata': 'https://www.wikidata.org/wiki/Q18031771', 'display_name': 'STX1A', 'level': 5, 'score': 0.53817457}, {'id': 'https://openalex.org/C2778256703', 'wikidata': 'https://www.wikidata.org/wiki/Q390407', 'display_name': 'Syntaxin', 'level': 4, 'score': 0.52744824}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.48905596}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.47957796}, {'id': 'https://openalex.org/C165254790', 'wikidata': 'https://www.wikidata.org/wiki/Q6416872', 'display_name': 'Kiss-and-run fusion', 'level': 5, 'score': 0.45790076}, {'id': 'https://openalex.org/C130316041', 'wikidata': 'https://www.wikidata.org/wiki/Q189206', 'display_name': 'Vesicle', 'level': 3, 'score': 0.4464518}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3944816}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.38596985}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3483459}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.30995739}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://ediss.uni-goettingen.de/bitstream/11858/00-1735-0000-0006-B5F0-D/1/siddiqui.pdf', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 190, 'referenced_works': ['https://openalex.org/W1484324228', 'https://openalex.org/W1499186559', 'https://openalex.org/W1501031736', 'https://openalex.org/W1504617983', 'https://openalex.org/W1509564548', 'https://openalex.org/W1520187505', 'https://openalex.org/W1522205897', 'https://openalex.org/W1533509738', 'https://openalex.org/W1540559701', 'https://openalex.org/W1542506006', 'https://openalex.org/W1545352687', 'https://openalex.org/W1555714096', 'https://openalex.org/W1570678799', 'https://openalex.org/W1574626580', 'https://openalex.org/W1589645365', 'https://openalex.org/W1600427108', 'https://openalex.org/W1607993356', 'https://openalex.org/W1618714882', 'https://openalex.org/W1700565657', 'https://openalex.org/W170382783', 'https://openalex.org/W1822252127', 'https://openalex.org/W1834247488', 'https://openalex.org/W185955435', 'https://openalex.org/W1875944393', 'https://openalex.org/W1879668390', 'https://openalex.org/W1894205392', 'https://openalex.org/W1927485791', 'https://openalex.org/W1963989662', 'https://openalex.org/W1966229750', 'https://openalex.org/W1966364658', 'https://openalex.org/W1967395384', 'https://openalex.org/W1967868876', 'https://openalex.org/W1969054503', 'https://openalex.org/W1970607892', 'https://openalex.org/W1970930136', 'https://openalex.org/W1971016259', 'https://openalex.org/W1972816955', 'https://openalex.org/W1973417166', 'https://openalex.org/W1974300656', 'https://openalex.org/W1976283234', 'https://openalex.org/W1976479871', 'https://openalex.org/W1976890690', 'https://openalex.org/W1978833026', 'https://openalex.org/W1979411632', 'https://openalex.org/W1979635240', 'https://openalex.org/W1983601929', 'https://openalex.org/W1984394526', 'https://openalex.org/W1984411571', 'https://openalex.org/W1986697042', 'https://openalex.org/W1989483611', 'https://openalex.org/W1989677215', 'https://openalex.org/W1992294030', 'https://openalex.org/W1993638185', 'https://openalex.org/W1994442356', 'https://openalex.org/W1994684691', 'https://openalex.org/W1996598000', 'https://openalex.org/W1998544609', 'https://openalex.org/W1998983314', 'https://openalex.org/W1999264521', 'https://openalex.org/W1999267161', 'https://openalex.org/W2002095327', 'https://openalex.org/W2002669633', 'https://openalex.org/W2003239731', 'https://openalex.org/W2003813143', 'https://openalex.org/W2005852124', 'https://openalex.org/W2007982098', 'https://openalex.org/W2009416811', 'https://openalex.org/W2009435363', 'https://openalex.org/W2010943743', 'https://openalex.org/W2011334399', 'https://openalex.org/W2011435140', 'https://openalex.org/W2011748656', 'https://openalex.org/W2013617213', 'https://openalex.org/W2014045979', 'https://openalex.org/W2014609146', 'https://openalex.org/W2015840191', 'https://openalex.org/W2016425872', 'https://openalex.org/W2016752908', 'https://openalex.org/W2016773062', 'https://openalex.org/W2017759753', 'https://openalex.org/W2019319677', 'https://openalex.org/W2021499235', 'https://openalex.org/W2021581599', 'https://openalex.org/W2023179858', 'https://openalex.org/W2023361978', 'https://openalex.org/W2027775552', 'https://openalex.org/W2028091095', 'https://openalex.org/W2030972230', 'https://openalex.org/W2033500343', 'https://openalex.org/W2033797809', 'https://openalex.org/W2034468530', 'https://openalex.org/W2035827727', 'https://openalex.org/W2035860044', 'https://openalex.org/W2036735884', 'https://openalex.org/W2036988598', 'https://openalex.org/W2039587858', 'https://openalex.org/W2040368827', 'https://openalex.org/W2040866860', 'https://openalex.org/W2042212641', 'https://openalex.org/W2044355928', 'https://openalex.org/W2045144602', 'https://openalex.org/W2045375596', 'https://openalex.org/W2047808133', 'https://openalex.org/W2048019766', 'https://openalex.org/W2049199355', 'https://openalex.org/W2054886459', 'https://openalex.org/W2054949067', 'https://openalex.org/W2055384905', 'https://openalex.org/W2056293200', 'https://openalex.org/W2058310774', 'https://openalex.org/W2058555144', 'https://openalex.org/W2061312580', 'https://openalex.org/W2061613461', 'https://openalex.org/W2063487710', 'https://openalex.org/W2063959590', 'https://openalex.org/W2064148637', 'https://openalex.org/W2064426755', 'https://openalex.org/W2065618120', 'https://openalex.org/W2066444607', 'https://openalex.org/W2067354100', 'https://openalex.org/W2068738089', 'https://openalex.org/W2073400297', 'https://openalex.org/W2077451533', 'https://openalex.org/W2078917390', 'https://openalex.org/W2079683808', 'https://openalex.org/W2080355472', 'https://openalex.org/W2083532524', 'https://openalex.org/W2085370553', 'https://openalex.org/W2085680244', 'https://openalex.org/W2086890785', 'https://openalex.org/W2086916379', 'https://openalex.org/W2088811553', 'https://openalex.org/W2089003364', 'https://openalex.org/W2089511766', 'https://openalex.org/W2092125712', 'https://openalex.org/W2092163457', 'https://openalex.org/W2093465143', 'https://openalex.org/W2094059060', 'https://openalex.org/W2094479838', 'https://openalex.org/W2098809038', 'https://openalex.org/W2100837269', 'https://openalex.org/W2104534420', 'https://openalex.org/W2104801664', 'https://openalex.org/W2105722661', 'https://openalex.org/W2108036428', 'https://openalex.org/W2114647945', 'https://openalex.org/W2116411945', 'https://openalex.org/W2117602113', 'https://openalex.org/W2117998295', 'https://openalex.org/W2118140199', 'https://openalex.org/W2120405274', 'https://openalex.org/W2123789039', 'https://openalex.org/W2125384218', 'https://openalex.org/W2125575826', 'https://openalex.org/W2128635872', 'https://openalex.org/W2128978059', 'https://openalex.org/W2129060802', 'https://openalex.org/W2129430733', 'https://openalex.org/W2130937674', 'https://openalex.org/W2131653836', 'https://openalex.org/W2132052757', 'https://openalex.org/W2135628573', 'https://openalex.org/W2136178051', 'https://openalex.org/W2140851030', 'https://openalex.org/W2142496373', 'https://openalex.org/W2143313571', 'https://openalex.org/W2144634347', 'https://openalex.org/W2145152234', 'https://openalex.org/W2147905210', 'https://openalex.org/W2152687237', 'https://openalex.org/W2155219479', 'https://openalex.org/W2156041267', 'https://openalex.org/W2157535945', 'https://openalex.org/W2158179560', 'https://openalex.org/W2163967516', 'https://openalex.org/W2164801278', 'https://openalex.org/W2164981865', 'https://openalex.org/W2165068760', 'https://openalex.org/W2165302477', 'https://openalex.org/W2168979413', 'https://openalex.org/W2169250706', 'https://openalex.org/W2170349574', 'https://openalex.org/W2186541052', 'https://openalex.org/W2234334930', 'https://openalex.org/W2396640993', 'https://openalex.org/W2404486451', 'https://openalex.org/W3135190686', 'https://openalex.org/W47492285', 'https://openalex.org/W63043245', 'https://openalex.org/W7725224'], 'related_works': ['https://openalex.org/W3122532699', 'https://openalex.org/W2802354374', 'https://openalex.org/W2601315132', 'https://openalex.org/W2159469027', 'https://openalex.org/W2150822049', 'https://openalex.org/W2132525593', 'https://openalex.org/W2093465143', 'https://openalex.org/W2074938737', 'https://openalex.org/W2071633399', 'https://openalex.org/W2047683495', 'https://openalex.org/W2047076739', 'https://openalex.org/W2045306333', 'https://openalex.org/W2038275015', 'https://openalex.org/W2030952494', 'https://openalex.org/W2022859590', 'https://openalex.org/W2009685989', 'https://openalex.org/W1977079697', 'https://openalex.org/W1967868876', 'https://openalex.org/W1732663100', 'https://openalex.org/W1520960173'], 'abstract_inverted_index': {'The': [0, 99, 781], 'fusion': [1], 'of': [2, 56, 112, 206, 295, 331, 423, 507, 579, 725, 796, 820, 886, 927], 'synaptic': [3, 74, 475, 562, 603], 'vesicles': [4, 476, 615], 'with': [5, 439, 471, 543], 'the': [6, 43, 58, 189, 207, 255, 261, 311, 329, 421, 494, 561, 635, 652, 691, 710, 726, 744, 818, 928], 'pre-synaptic': [18, 802], 'plasma': [19], 'membrane': [20, 79, 386], 'is': [21, 95, 365, 417, 834, 942], 'mediated': [22], 'by': [23, 371, 907], 'SNARE': [24, 59, 165, 278, 312, 348, 453, 580, 648, 727, 797, 821, 929], 'proteins.': [36], 'This': [37], 'work': [38], 'provides': [39], 'key': [40], 'insights': [41, 742], 'into': [42, 743], 'behaviour': [55], 'synaptobrevin,': [57], 'protein': [60, 547], 'localized': [61, 559], 'to': [73, 243, 259, 527, 560, 600, 777], 'vesicles,': [75], 'in': [76, 97, 147, 164, 240, 420, 530, 602, 670, 762, 801, 836, 982], 'its': [77, 224, 617], 'native': [78], 'organelle': [80], 'and': [92, 203, 293, 333, 402, 473, 564, 668, 673, 783, 838], 'when': [93, 905], 'it': [94, 949], 'reconstituted': [96, 113, 459], 'liposomes.': [98], 'reactivity': [111], 'synaptobrevin': [114, 145, 238, 472, 601], 'has': [115, 509, 524, 871], 'remained': [116], 'controversial.': [128], 'Recent': [129], 'studies': [130], 'have': [131], 'suggested': [132, 351], 'that': [133, 352, 586, 817, 853, 924, 965], 'inserted': [146], 'membranes': [148, 241, 542], 'does': [149], 'not': [150, 651, 943], 'readily': [151], 'engage': [163], 'complexes': [166, 798, 966], '(Hu': [167], 'et': [168, 172], 'al.,': [169, 184], '2002;': [170], 'Kweon': [171], '2003b).': [185], 'I': [186, 583, 815], 'therefore': [187], 'explored': [188], 'binding': [190, 599, 688], 'characteristics': [202], 'assembly': [204, 313, 350, 364, 455], 'pathway': [205, 314], 'SNAREs': [208, 508], 'on': [209, 315, 347, 457, 474, 690, 891, 968], 'synaptobrevin-bearing': [221], 'membranes.': [222, 316], 'Like': [223], 'soluble': [225], 'domain,': [237], 'anchored': [239], 'binds': [242], 'syntaxin/SNAP-25': [256, 598], 'acceptor': [257], 'complex': [258, 349, 454, 581, 703, 728, 833, 887, 930], 'form': [260], 'stable': [273], 'tetra': [274], 'helical': [275], 'coiled': [276], 'coil': [277], 'bundle.': [279], 'Kinetic': [280], 'simulations': [292], 'fitting': [294], 'experimental': [296], 'data': [297], 'helped': [298], 'unravel': [310], 'Monitoring': [328], 'effects': [330], 'endogenous': [332], 'extraneous': [334], 'factors': [346], 'a': [366, 565, 707, 944], 'robust': [367], 'process,': [368], 'largely': [369], 'unaffected': [370], 'brain': [383], 'cytosolic': [384], 'factors,': [385], 'fluidity,': [387], 'chaotropicity,': [399], 'divalent': [400], 'ions': [401], 'lipid': [403], 'composition': [404], 'but': [405, 650], 'considerably': [418], 'enhanced': [419], 'presence': [422], 'weak': [424], 'counter-ions.': [436], 'In': [437, 706], 'agreement': [438], 'these': [440], 'observations,': [441], 'rate': [456], 'liposomes': [458], 'was': [477, 799], 'comparable.': [489], 'Being': [490], 'highly': [491], 'reactive': [492], 'molecules,': [493], 'regulation': [506], 'considerable': [510], 'importance.': [511], 'Synaptobrevin': [523], 'been': [525], 'found': [526, 816, 890], 'be': [528, 760, 962], 'associated': [529], 'synaptophysin,': [544], 'an': [545], 'abundant': [546], 'vesicle': [563], 'potential': [566], 'regulator': [578], 'assembly.': [582], 'showed': [584], 'here': [585], 'causes': [616], 'dissociation': [618], 'from': [619], 'synaptophysin.Three': [631], 'monoclonal': [632], 'antibodies': [633, 722, 758], 'recognizing': [634], 'ternary': [636], 'complex,': [649], 'monomers,': [653], 'were': [654, 704], 'successfully': [655], 'raised': [667], 'characterised': [669], 'immunoblots,': [671], 'cell-lines': [672], 'plasma-membrane': [685], 'sheets.': [686], 'Their': [687], 'sites': [689], 'mapped.': [705], 'functional': [708, 764], 'assay,': [709], 'abolished': [723], 'disassembly': [724, 745, 926], 'thus': [740], 'providing': [741], 'machinery.The': [757], 'can': [759], 'used': [761], 'other': [763], 'assays': [776], 'answer': [778], 'pertinent': [779], 'questions.': [780], 'status': [782], 'dynamics': [795], 'probed': [800], 'nerve-terminals.': [814], 'amount': [819, 874], 'comparable': [835], 'resting': [837], 'stimulated': [839], 'synaptosomes,': [851], 'suggesting': [852, 923], 'they': [854], 'rapidly': [855], 'disassemble': [856], 'immediately': [868], 'after': [869], 'exocytosis': [870], 'occurred.': [872], 'Some': [873], 'was,': [888], 'however,': [889], 'isolated': [892, 969], 'organelles': [893, 981], 'monitored': [906], 'direct': [908], 'imaging': [909], 'or': [910], 'immunoblotting,': [911], 'rapid': [925], 'pre-requisite': [945], 'for': [946], 'endocytosis,': [947], 'though': [948], 'cannot': [961], 'ruled': [963], 'out': [964], 'formed': [967], 'vitro.': [983]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1587126988', 'counts_by_year': [], 'updated_date': '2024-12-16T01:55:09.364272', 'created_date': '2016-06-24'}