Publication Information

{'id': 'https://openalex.org/W1581817894', 'doi': None, 'title': '[Cross resistance to mefloquine and halofantrine in a case of P. falciparum malaria contracted in Sierra Leone].', 'display_name': '[Cross resistance to mefloquine and halofantrine in a case of P. falciparum malaria contracted in Sierra Leone].', 'publication_year': 1990, 'publication_date': '1990-01-01', 'ids': {'openalex': 'https://openalex.org/W1581817894', 'mag': '1581817894', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2190703'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2190703', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111986578', 'display_name': 'R. Felix', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I39804081', 'display_name': 'Sorbonne Université', 'ror': 'https://ror.org/02en5vm52', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I39804081']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'R Félix', 'raw_affiliation_strings': ['CHU Pitié-Salpêtrière, Service des Maladies parasitaires et tropicales, Paris.'], 'affiliations': [{'raw_affiliation_string': 'CHU Pitié-Salpêtrière, Service des Maladies parasitaires et tropicales, Paris.', 'institution_ids': ['https://openalex.org/I39804081']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108157107', 'display_name': 'Frédérick Gay', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'F Gay', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052057430', 'display_name': 'A Lyogoubi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A Lyogoubi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029953398', 'display_name': 'M D Bustos', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M D Bustos', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108102545', 'display_name': 'B. Diquet', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'B Diquet', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107842636', 'display_name': 'M Danis', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Danis', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5011046182', 'display_name': 'M Gentilini', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Gentilini', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.717, 'has_fulltext': False, 'cited_by_count': 12, 'citation_normalized_percentile': {'value': 0.707923, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '83', 'issue': '1', 'first_page': '43', 'last_page': '5'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9753, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9753, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/halofantrine', 'display_name': 'Halofantrine', 'score': 0.9881067}, {'id': 'https://openalex.org/keywords/quinine', 'display_name': 'Quinine', 'score': 0.6707983}, {'id': 'https://openalex.org/keywords/thais', 'display_name': 'Thais', 'score': 0.48236626}], 'concepts': [{'id': 'https://openalex.org/C2777199930', 'wikidata': 'https://www.wikidata.org/wiki/Q736270', 'display_name': 'Mefloquine', 'level': 4, 'score': 0.98886144}, {'id': 'https://openalex.org/C2777498558', 'wikidata': 'https://www.wikidata.org/wiki/Q947595', 'display_name': 'Halofantrine', 'level': 5, 'score': 0.9881067}, {'id': 'https://openalex.org/C3018567284', 'wikidata': 'https://www.wikidata.org/wiki/Q1044', 'display_name': 'Sierra leone', 'level': 2, 'score': 0.849031}, {'id': 'https://openalex.org/C2777425658', 'wikidata': 'https://www.wikidata.org/wiki/Q422438', 'display_name': 'Chloroquine', 'level': 3, 'score': 0.7786751}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.77399856}, {'id': 'https://openalex.org/C2775867548', 'wikidata': 'https://www.wikidata.org/wiki/Q1897162', 'display_name': 'Parasitemia', 'level': 4, 'score': 0.71853167}, {'id': 'https://openalex.org/C2777617192', 'wikidata': 'https://www.wikidata.org/wiki/Q189522', 'display_name': 'Quinine', 'level': 3, 'score': 0.6707983}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.6649558}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5071826}, {'id': 'https://openalex.org/C2780714494', 'wikidata': 'https://www.wikidata.org/wiki/Q148925', 'display_name': 'Thais', 'level': 2, 'score': 0.48236626}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.35174674}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.35032284}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.28070164}, {'id': 'https://openalex.org/C45355965', 'wikidata': 'https://www.wikidata.org/wiki/Q1643441', 'display_name': 'Socioeconomics', 'level': 1, 'score': 0.077313006}, {'id': 'https://openalex.org/C149923435', 'wikidata': 'https://www.wikidata.org/wiki/Q37732', 'display_name': 'Demography', 'level': 1, 'score': 0.06563762}, {'id': 'https://openalex.org/C144024400', 'wikidata': 'https://www.wikidata.org/wiki/Q21201', 'display_name': 'Sociology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': True}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D003429', 'descriptor_name': 'Cross Reactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010616', 'descriptor_name': 'Phenanthrenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010616', 'descriptor_name': 'Phenanthrenes', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D010616', 'descriptor_name': 'Phenanthrenes', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2190703', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.84, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2500304171', 'https://openalex.org/W2467024671', 'https://openalex.org/W2410056375', 'https://openalex.org/W2409811942', 'https://openalex.org/W2400008155', 'https://openalex.org/W2394565064', 'https://openalex.org/W2232851504', 'https://openalex.org/W1581817894', 'https://openalex.org/W1477469345', 'https://openalex.org/W134126238'], 'abstract_inverted_index': {'Malaria': [0], 'caused': [1], 'by': [2], 'P.': [3, 92], 'falciparum': [4, 93], 'occurred': [5], 'during': [6], 'prophylaxis': [7], 'with': [8, 22, 32, 41, 53], 'mefloquine': [9, 70], 'upon': [10], 'return': [11], 'from': [12, 95], 'Sierra': [13, 96], 'Leone': [14, 97], '(zone': [15], 'II).': [16], 'A': [17], 'typical': [18], 'and': [19, 46, 79], 'not': [20], 'recognized,': [21], 'negative': [23], 'results': [24], 'of': [25, 34, 38, 91, 106, 112], 'initial': [26], 'hematological': [27], 'examinations.': [28], 'Diagnosed': [29], 'on': [30], 'D.26': [31], 'parasitemia': [33, 48], '0.2%.': [35], 'Successful': [36, 51], 'treatment': [37, 52], 'clinical': [39], 'symptoms': [40], 'halofantrine': [42, 81], 'but': [43], 'increased': [44], 'anemia': [45], 'positive': [47], 'at': [49], 'D.7.': [50], 'chloroquine.': [54], 'Chemosensitivity': [55], 'tests': [56], 'confirmed': [57], 'sensitivity': [58, 62], 'to': [59, 63, 69, 80, 98, 101], 'chloroquine,': [60], 'threshold': [61], 'quinine': [64], '(IC50': [65, 71, 82], '=': [66, 72, 83, 87], '297),': [67], 'resistance': [68], '76)': [73], 'despite': [74], 'high': [75], 'levels': [76], 'in': [77, 109, 117], 'bloods,': [78], '7-laboratory': [84], 'normal': [85], 'value': [86], '1).': [88], 'This': [89], 'cross-resistance': [90], 'originating': [94], 'mefloquine-halofantrine': [99], 'seems': [100], 'be': [102], 'the': [103], 'first': [104], 'observation': [105], 'this': [107], 'danger': [108], 'Africa.': [110], 'Prescription': [111], 'chloroquine': [113], 'is': [114], 'still': [115], 'imperative': [116], 'zone': [118], '11': [119], 'countries.': [120]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1581817894', 'counts_by_year': [], 'updated_date': '2024-12-14T10:33:45.446518', 'created_date': '2016-06-24'}