Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W15795846', 'doi': None, 'title': '[Increased plasma membrane permeability for Ca2+ in radiation-induced thymocyte apoptosis].', 'display_name': '[Increased plasma membrane permeability for Ca2+ in radiation-induced thymocyte apoptosis].', 'publication_year': 1997, 'publication_date': '1997-03-01', 'ids': {'openalex': 'https://openalex.org/W15795846', 'mag': '15795846', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9181965'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9181965', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5074847048', 'display_name': 'A. S. Shevchenko', 'orcid': 'https://orcid.org/0000-0002-3036-9306'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A S Shevchenko', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067359095', 'display_name': 'Vladimir L. Gabai', 'orcid': 'https://orcid.org/0000-0003-4505-4718'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'V L Gabaĭ', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007611857', 'display_name': 'В. О. Кобялко', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'V O Kobialko', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015434034', 'display_name': 'Ю М Макарова', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Iu M Makarova', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5079900603', 'display_name': 'Т. С. Шевченко', 'orcid': 'https://orcid.org/0000-0003-4073-3711'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'T S Shevchenko', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.119, 'has_fulltext': False, 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.380979, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 69, 'max': 71}, 'biblio': {'volume': '37', 'issue': '2', 'first_page': '220', 'last_page': '7'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.5531, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.5531, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12828', 'display_name': 'Plant Genetic and Mutation Studies', 'score': 0.5056, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10433', 'display_name': 'Carcinogens and Genotoxicity Assessment', 'score': 0.4504, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thymocyte', 'display_name': 'Thymocyte', 'score': 0.6600369}, {'id': 'https://openalex.org/keywords/fragmentation', 'display_name': 'Fragmentation', 'score': 0.56009406}, {'id': 'https://openalex.org/keywords/membrane-permeability', 'display_name': 'Membrane permeability', 'score': 0.5347043}], 'concepts': [{'id': 'https://openalex.org/C43759708', 'wikidata': 'https://www.wikidata.org/wiki/Q3749256', 'display_name': 'DNA fragmentation', 'level': 4, 'score': 0.7742763}, {'id': 'https://openalex.org/C2778954852', 'wikidata': 'https://www.wikidata.org/wiki/Q7799635', 'display_name': 'Thymocyte', 'level': 4, 'score': 0.6600369}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.62799156}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5674676}, {'id': 'https://openalex.org/C191015642', 'wikidata': 'https://www.wikidata.org/wiki/Q1132459', 'display_name': 'Fragmentation (computing)', 'level': 2, 'score': 0.56009406}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.55944145}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.55794173}, {'id': 'https://openalex.org/C120882062', 'wikidata': 'https://www.wikidata.org/wiki/Q28352', 'display_name': 'Permeability (electromagnetism)', 'level': 3, 'score': 0.54166955}, {'id': 'https://openalex.org/C2992270614', 'wikidata': 'https://www.wikidata.org/wiki/Q29548', 'display_name': 'Membrane permeability', 'level': 3, 'score': 0.5347043}, {'id': 'https://openalex.org/C111337013', 'wikidata': 'https://www.wikidata.org/wiki/Q2737837', 'display_name': 'Irradiation', 'level': 2, 'score': 0.5293924}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.43312168}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.28254545}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.27471796}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2590425}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.15647009}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C185544564', 'wikidata': 'https://www.wikidata.org/wiki/Q81197', 'display_name': 'Nuclear physics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D002122', 'descriptor_name': 'Calcium Chloride', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D002463', 'descriptor_name': 'Cell Membrane Permeability', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D013950', 'descriptor_name': 'Thymus Gland', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017301', 'descriptor_name': 'Ca(2+) Mg(2+)-ATPase', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D017301', 'descriptor_name': 'Ca(2+) Mg(2+)-ATPase', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D017301', 'descriptor_name': 'Ca(2+) Mg(2+)-ATPase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002122', 'descriptor_name': 'Calcium Chloride', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D002122', 'descriptor_name': 'Calcium Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002132', 'descriptor_name': 'Calcium Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002463', 'descriptor_name': 'Cell Membrane Permeability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053938', 'descriptor_name': 'DNA Fragmentation', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D053938', 'descriptor_name': 'DNA Fragmentation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005720', 'descriptor_name': 'Gamma Rays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013950', 'descriptor_name': 'Thymus Gland', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D013950', 'descriptor_name': 'Thymus Gland', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014638', 'descriptor_name': 'Vanadates', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D014638', 'descriptor_name': 'Vanadates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9181965', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.52, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2414597565', 'https://openalex.org/W2410895222', 'https://openalex.org/W2349196594', 'https://openalex.org/W2144129447', 'https://openalex.org/W2030257965', 'https://openalex.org/W2003173723', 'https://openalex.org/W198769452', 'https://openalex.org/W1980045425', 'https://openalex.org/W1910407513', 'https://openalex.org/W124089116'], 'abstract_inverted_index': {'Parameters': [0], 'of': [1, 12, 21, 39, 57, 67, 74, 85, 111, 123, 135, 137, 143, 145, 162, 177], 'the': [2, 10, 15, 18, 22, 26, 44, 50, 58, 68, 75, 83, 86, 90, 101, 124, 129, 138, 146, 152, 163, 168, 175], 'Ca2+': [3, 76, 126, 165, 170], 'permeability': [4, 61, 127, 149, 166], '(the': [5], '45Ca': [6, 23, 51, 69, 87], 'influx': [7, 52, 88], 'rate': [8, 20, 53, 66, 84], 'in': [9, 31, 89, 100, 106, 113, 128], 'presence': [11], 'orthovanadate': [13], 'blocking': [14], 'Ca(2+)-ATPhase,': [16], 'and': [17, 25, 167], 'initial': [19, 65], 'uptake)': [24], 'DNA': [27, 102, 139], 'fragmentation': [28, 103], 'were': [29], 'determined': [30], 'rat': [32], 'thymocytes': [33, 131], 'after': [34, 48, 109], 'gamma-irradiation-induced': [35], '(with': [36], 'a': [37, 133], 'dose': [38], '5': [40], 'Gy)': [41], 'apoptosis.': [42], 'Within': [43], 'first': [45], '30-90': [46], 'min': [47, 108], 'irradiation,': [49], 'that': [54, 71, 160], 'is': [55, 72], 'characteristic': [56, 73], 'membrane': [59, 125, 147], 'passive': [60, 148, 164], 'remained': [62], 'unchanged.': [63], 'The': [64, 156], 'uptake': [70], 'exchange': [77], 'almost': [78], 'doubled.': [79], 'In': [80], '90-180': [81], 'min,': [82], 'irradiated': [91, 130, 179], 'cells': [92], 'increased': [93], '1.5': [94], 'to': [95, 119], '2.0': [96], 'times.': [97], 'An': [98], 'increase': [99], 'was': [104], 'observed': [105], '90-120': [107], 'irradiation': [110], 'thymocytes;': [112], '3': [114], 'h,': [115], 'it': [116], 'developed': [117], 'up': [118], '50%.': [120], 'Thus,': [121], 'modification': [122], 'precedes': [132], 'stage': [134], 'initiation': [136], 'degradation.': [140], 'A': [141], 'degree': [142], 'disturbance': [144, 161], 'increases': [150], 'as': [151], 'thymocyte': [153], 'apoptosis': [154, 176], 'progresses.': [155], 'obtained': [157], 'data': [158], 'suggest': [159], 'intracellular': [169], 'homeostasis': [171], 'are': [172], 'responsible': [173], 'for': [174], 'lethally': [178], 'thymocytes.': [180]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W15795846', 'counts_by_year': [], 'updated_date': '2024-12-18T04:35:12.158796', 'created_date': '2016-06-24'}