Publication Information

{'id': 'https://openalex.org/W1576704182', 'doi': 'https://doi.org/10.21236/ada417961', 'title': 'Molecular Dissection of the S Phase Transcriptional Program Controlled by Cyclin E/P220 NPAT Signaling Pathway', 'display_name': 'Molecular Dissection of the S Phase Transcriptional Program Controlled by Cyclin E/P220 NPAT Signaling Pathway', 'publication_year': 2003, 'publication_date': '2003-04-01', 'ids': {'openalex': 'https://openalex.org/W1576704182', 'doi': 'https://doi.org/10.21236/ada417961', 'mag': '1576704182'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.21236/ada417961', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'report', 'type_crossref': 'report', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5023444694', 'display_name': 'Wei Yue', 'orcid': 'https://orcid.org/0000-0002-7895-183X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yue Wei', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5104047690', 'display_name': 'Jeffrey Wade Harper', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jeffrey Harper', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 59}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 0.9917, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C120089663', 'wikidata': 'https://www.wikidata.org/wiki/Q59250999', 'display_name': 'Cyclin', 'level': 4, 'score': 0.41786456}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.41065866}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40829176}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.33681977}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.30610394}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.28276002}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.1851308}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.21236/ada417961', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W1976144441', 'https://openalex.org/W2010164793', 'https://openalex.org/W2029080338', 'https://openalex.org/W2041634189', 'https://openalex.org/W2053359084', 'https://openalex.org/W2100287099', 'https://openalex.org/W2107244138', 'https://openalex.org/W2113768195', 'https://openalex.org/W2116855282', 'https://openalex.org/W2135212191', 'https://openalex.org/W2138165292'], 'related_works': ['https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2899084033', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2607424097', 'https://openalex.org/W2606230654', 'https://openalex.org/W2319480705', 'https://openalex.org/W2034625591', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'Abstract': [0], ':': [1], 'Cyclin': [2], 'E/Cdk2,': [3], 'a': [4, 31], 'central': [5], 'regulator': [6], 'of': [7, 23, 38, 59, 73, 80, 92, 110, 116, 134, 154, 157, 172, 184], 'the': [8, 24, 45, 108, 152, 173, 185], 'G1/S': [9, 186], 'transition,': [10], 'coordinates': [11], 'multiple': [12, 182], 'cell': [13, 103, 124], 'cycle': [14, 104, 125], 'events,': [15], 'including': [16], 'DNA': [17], 'replication,': [18], 'centrosome': [19], 'duplication,': [20], 'and': [21, 50, 102, 178], 'activation': [22, 37, 62], 'E2F': [25], 'transcriptional': [26, 61], 'program.': [27], 'Recent': [28], 'studies': [29], 'suggest': [30], 'role': [32], 'for': [33, 71], 'cyclin': [34, 174], 'E/Cdk2': [35, 175], 'in': [36, 51, 83, 107, 127, 146, 151], 'histone': [39, 60, 138, 143], 'transcription': [40], 'during': [41], 'S': [42, 100], 'phase': [43], 'via': [44], 'Cajal': [46], 'body-associated': [47], 'protein': [48], 'p22ONPAT,': [49], 'addition,': [52], 'p220': [53, 68, 130, 158, 166], 'can': [54], 'promote': [55], 'S-phase': [56], 'entry': [57], 'independently': [58], 'when': [63], 'overexpressed.': [64], 'We': [65], 'found': [66], 'that': [67, 165], 'is': [69, 167], 'required': [70, 140], 'proliferation': [72], 'HCT116': [74], 'cells,': [75], 'as': [76], 'assessed': [77], 'after': [78], 'expression': [79, 133, 145], 'Cre': [81], 'recombinase': [82], 'p220fl0x/-cells.': [84], 'This': [85], 'defect': [86], 'was': [87], 'due': [88], 'to': [89, 95, 129, 180], 'an': [90, 168], 'inability': [91], 'these': [93], 'cells': [94], 'transit': [96], 'from': [97], '00/01': [98], 'into': [99], 'phase,': [101], 'arrest': [105, 126], 'occurred': [106], 'presence': [109], 'elevated': [111], 'Cdk2': [112, 160], 'kinase': [113], 'activity.': [114], 'Expression': [115], 'human': [117], 'papillomavirus': [118], 'E7,': [119], 'but': [120], 'not': [121], 'E6,': [122], 'eliminated': [123], 'response': [128], 'depletion.': [131], 'Optimal': [132], 'all': [135], 'four': [136], 'core': [137], 'genes': [139], 'p220.': [141], 'Basal': [142], 'H4': [144], 'G0/G1,': [147], 'although': [148], 'p220-dependent,': [149], 'occurs': [150], 'absence': [153], 'detectable': [155], 'phosphorylation': [156], 'on': [159], 'sites.': [161], 'These': [162], 'finding': [163], 'indicate': [164], 'essential': [169], 'downstream': [170], 'component': [171], 'signaling': [176], 'pathway': [177], 'functions': [179], 'coordinate': [181], 'elements': [183], 'transition.': [187]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1576704182', 'counts_by_year': [], 'updated_date': '2024-12-11T03:56:31.659619', 'created_date': '2016-06-24'}