Publication Information

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'resistant,': [168], 'thus': [169], 'both': [171], 'there': [173], 'high': [176], 'risk': [177], 'relapse.': [179], 'Consequently,': [180], 'novel': [181], 'are': [183, 216, 238, 416, 680, 699], 'required': [184], 'likely': [187], 'arise': [188], 'an': [190, 242, 310, 628], 'understanding': [192, 267], 'biology.': [196], '\r\nRecent': [198], 'members': [203], 'fibroblast': [206], 'growth': [207], 'factor': [208], '(FGFR)': [210], 'family': [211], 'receptors': [215, 286], 'deregulated': [217], 'cancer.': [220, 248], 'Indeed': [221], 'FGFR1': [222], 'gene': [223, 237], 'amplified': [225], '9%': [227], 'single': [232], 'nucleotide': [233], 'polymorphisms': [234], 'FGFR2': [236], 'strongly': [239], 'associated': [240], 'with': [241, 370, 435, 477, 562], 'increased': [243, 438], 'probability': [244, 589], 'Using': [249, 330, 392], 'models': [250, 637, 695], 'carcinoma': [253], '(4T1,': [254], '4TO7,': [255, 298], '168FARN': [256, 299], '67NR': [258, 301], 'cell': [259, 288, 302, 380, 384, 404, 447, 549], 'lines),': [260], 'our': [261, 618, 647, 675], 'study': [262], 'aimed': [263], 'at': [264], 'better': [266], 'how': [269], 'FGFRs': [270, 314, 408, 623], 'contribute': [271, 402, 536], 'tumorigenesis.': [274], 'Furthermore': [275], 'we': [276, 294, 338, 396, 426, 437, 451], 'analysed': [277], 'effects': [279, 421], 'blocking': [281, 336], 'activity': [283, 342, 362], 'lines': [289, 303, 381], 'primary': [291], 'tumors.\r\nIn': [292], 'vitro,': [293], 'showed': [295, 527], '4T1,': [297], 'co-express': [304], 'FGF': [305], 'ligands': [306], 'FGFRs,': [308, 337], 'suggesting': [309], 'autocrine': [311, 371], 'loop': [312], 'activating': [313], 'which': [315], 'leads': [316, 662], 'constitutive': [319], 'basal': [320, 341], 'activation': [321, 605], 'downstream': [323, 406], 'signaling': [324, 359, 373, 458, 610, 654], 'pathways,': [325], 'MAPK': [327, 364], 'PI3K/AKT.': [329], 'TKI258,': [331, 436], 'inhibitor': [335], 'inhibited': [339], 'FGFRs.': [344], 'This': [345], 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464, 645], 'vivo,': [450], 'describe': [452], 'inhibits': [456], 'mice': [460, 470], 'bearing': [461, 471], '4T1-induced': [462], 'tumors.': [463], 'addition,': [465, 646], 'daily': [466], 'oral': [467], '4T1-': [472], '67NR-': [474], 'tumors': [476, 687], 'over': [479], '14': [480], 'days,': [481], 'significantly': [482], 'reduces': [483], 'tumor': [484, 666], 'outgrowth': [485, 667], 'decreases': [487], 'metastasis,': [490], 'showing': [491, 575], 'blockade': [493, 651], 'has': [496, 627], 'strong': [497], 'anti-tumor': [498], 'anti-metastatic': [500], 'activities.': [501], '\r\nTwo': [502], 'microarray': [503], 'analyses': [504, 526], 'performed': [505], 'treated': [507, 684], 'tumors,': [512], 'led': [513], 'identification': [516], 'genes': [518, 532, 561, 578, 601, 678], 'were': [520, 533], 'regulated': [521], 'treatment.': [524], 'Detailed': [525], 'some': [529], 'known': [534], 'metastatic': [539, 591], 'process': [540], '(matrix': [541], 'metalloproteinases': [542], 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