Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1561041814', 'doi': 'https://doi.org/10.1038/nm.3893', 'title': 'Inflammasomes: mechanism of action, role in disease, and therapeutics', 'display_name': 'Inflammasomes: mechanism of action, role in disease, and therapeutics', 'publication_year': 2015, 'publication_date': '2015-06-29', 'ids': {'openalex': 'https://openalex.org/W1561041814', 'doi': 'https://doi.org/10.1038/nm.3893', 'mag': '1561041814', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26121197', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4519035'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/nm.3893', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S203256638', 'display_name': 'Nature Medicine', 'issn_l': '1078-8956', 'issn': ['1078-8956', '1546-170X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc4519035?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015609876', 'display_name': 'Haitao Guo', 'orcid': 'https://orcid.org/0000-0002-2737-2723'}, 'institutions': [{'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Haitao Guo', 'raw_affiliation_strings': ['The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA'], 'affiliations': [{'raw_affiliation_string': 'The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA', 'institution_ids': ['https://openalex.org/I114027177']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041554852', 'display_name': 'Justin Callaway', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Justin B Callaway', 'raw_affiliation_strings': ['The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA'], 'affiliations': [{'raw_affiliation_string': 'The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA', 'institution_ids': ['https://openalex.org/I114027177']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101673864', 'display_name': 'Jenny P.-Y. Ting', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Jenny P-Y Ting', 'raw_affiliation_strings': ['Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA', 'institution_ids': ['https://openalex.org/I114027177']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5101673864'], 'corresponding_institution_ids': ['https://openalex.org/I114027177'], 'apc_list': {'value': 9750, 'currency': 'EUR', 'value_usd': 11690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 28.383, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 2745, 'citation_normalized_percentile': {'value': 0.999741, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '21', 'issue': '7', 'first_page': '677', 'last_page': '687'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11078', 'display_name': 'Inflammasome and immune disorders', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11078', 'display_name': 'Inflammasome and immune disorders', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11171', 'display_name': 'Diabetes and associated disorders', 'score': 0.9753, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10528', 'display_name': 'Adipokines, Inflammation, and Metabolic Diseases', 'score': 0.962, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777209026', 'wikidata': 'https://www.wikidata.org/wiki/Q412405', 'display_name': 'Inflammasome', 'level': 3, 'score': 0.9480064}, {'id': 'https://openalex.org/C136449434', 'wikidata': 'https://www.wikidata.org/wiki/Q428253', 'display_name': 'Innate immune system', 'level': 3, 'score': 0.6792196}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.61712533}, {'id': 'https://openalex.org/C89611455', 'wikidata': 'https://www.wikidata.org/wiki/Q6804646', 'display_name': 'Mechanism (biology)', 'level': 2, 'score': 0.53805226}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.52980226}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5030028}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.45659742}, {'id': 'https://openalex.org/C139964883', 'wikidata': 'https://www.wikidata.org/wiki/Q14901964', 'display_name': 'Caspase 1', 'level': 4, 'score': 0.45157567}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.44927984}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.41895342}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.3337466}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.29421437}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12381977}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111472728', 'wikidata': 'https://www.wikidata.org/wiki/Q9471', 'display_name': 'Epistemology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004194', 'descriptor_name': 'Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D058847', 'descriptor_name': 'Inflammasomes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D058990', 'descriptor_name': 'Molecular Targeted Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058847', 'descriptor_name': 'Inflammasomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018448', 'descriptor_name': 'Models, Immunological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/nm.3893', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S203256638', 'display_name': 'Nature Medicine', 'issn_l': '1078-8956', 'issn': ['1078-8956', '1546-170X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4519035', 'pdf_url': 'https://europepmc.org/articles/pmc4519035?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519035', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.17615/qs9b-1140', 'pdf_url': 'https://cdr.lib.unc.edu/downloads/wm117w34s', 'source': {'id': 'https://openalex.org/S4306401075', 'display_name': 'Carolina Digital Repository (University of North Carolina at Chapel Hill)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I114027177', 'host_organization_name': 'University of North Carolina at Chapel Hill', 'host_organization_lineage': ['https://openalex.org/I114027177'], 'host_organization_lineage_names': ['University of North Carolina at Chapel Hill'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26121197', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4519035', 'pdf_url': 'https://europepmc.org/articles/pmc4519035?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.76, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 147, 'referenced_works': ['https://openalex.org/W1529674879', 'https://openalex.org/W1636793459', 'https://openalex.org/W1715575057', 'https://openalex.org/W1743744546', 'https://openalex.org/W1859128422', 'https://openalex.org/W1958466825', 'https://openalex.org/W1964253344', 'https://openalex.org/W1966914633', 'https://openalex.org/W1967139098', 'https://openalex.org/W1967535998', 'https://openalex.org/W1972483153', 'https://openalex.org/W1974412717', 'https://openalex.org/W1975014158', 'https://openalex.org/W1975145629', 'https://openalex.org/W1976129489', 'https://openalex.org/W1976597734', 'https://openalex.org/W1984391988', 'https://openalex.org/W1984632540', 'https://openalex.org/W1987329700', 'https://openalex.org/W1988197452', 'https://openalex.org/W1993162037', 'https://openalex.org/W1993976394', 'https://openalex.org/W1997668790', 'https://openalex.org/W1998522372', 'https://openalex.org/W1998735049', 'https://openalex.org/W2007479707', 'https://openalex.org/W2008869160', 'https://openalex.org/W2009523990', 'https://openalex.org/W2012037560', 'https://openalex.org/W2014602273', 'https://openalex.org/W2015283405', 'https://openalex.org/W2016391141', 'https://openalex.org/W2017237017', 'https://openalex.org/W2018607502', 'https://openalex.org/W2022765384', 'https://openalex.org/W2024262729', 'https://openalex.org/W2024378513', 'https://openalex.org/W2026212701', 'https://openalex.org/W2026400708', 'https://openalex.org/W2028368428', 'https://openalex.org/W2030919251', 'https://openalex.org/W2030997154', 'https://openalex.org/W2032370476', 'https://openalex.org/W2034230597', 'https://openalex.org/W2034946303', 'https://openalex.org/W2037600884', 'https://openalex.org/W2042288276', 'https://openalex.org/W2042433863', 'https://openalex.org/W2042816890', 'https://openalex.org/W2042851093', 'https://openalex.org/W2046088592', 'https://openalex.org/W2048211245', 'https://openalex.org/W2049737588', 'https://openalex.org/W2050259192', 'https://openalex.org/W2050449334', 'https://openalex.org/W2051303794', 'https://openalex.org/W2052617165', 'https://openalex.org/W2052874989', 'https://openalex.org/W2052895824', 'https://openalex.org/W2055727949', 'https://openalex.org/W2057039052', 'https://openalex.org/W2058803210', 'https://openalex.org/W2060977160', 'https://openalex.org/W2064856766', 'https://openalex.org/W2064874359', 'https://openalex.org/W2065653369', 'https://openalex.org/W2067820229', 'https://openalex.org/W2068619092', 'https://openalex.org/W2070745672', 'https://openalex.org/W2073561387', 'https://openalex.org/W2074954748', 'https://openalex.org/W2076633494', 'https://openalex.org/W2077101573', 'https://openalex.org/W2078819049', 'https://openalex.org/W2078850432', 'https://openalex.org/W2079923062', 'https://openalex.org/W2080827095', 'https://openalex.org/W2081262717', 'https://openalex.org/W2082400315', 'https://openalex.org/W2082857443', 'https://openalex.org/W2084158898', 'https://openalex.org/W2084998907', 'https://openalex.org/W2086406618', 'https://openalex.org/W2086659139', 'https://openalex.org/W2088254488', 'https://openalex.org/W2089503694', 'https://openalex.org/W2090548255', 'https://openalex.org/W2094012816', 'https://openalex.org/W2094584625', 'https://openalex.org/W2094629035', 'https://openalex.org/W2094631886', 'https://openalex.org/W2096317294', 'https://openalex.org/W2096618637', 'https://openalex.org/W2098000380', 'https://openalex.org/W2098456337', 'https://openalex.org/W2098653855', 'https://openalex.org/W2100748836', 'https://openalex.org/W2101118037', 'https://openalex.org/W2106393574', 'https://openalex.org/W2106427090', 'https://openalex.org/W2109789710', 'https://openalex.org/W2113511371', 'https://openalex.org/W2114266096', 'https://openalex.org/W2117361576', 'https://openalex.org/W2118403357', 'https://openalex.org/W2119098586', 'https://openalex.org/W2121952285', 'https://openalex.org/W2123531771', 'https://openalex.org/W2124688365', 'https://openalex.org/W2124848390', 'https://openalex.org/W2126693439', 'https://openalex.org/W2127314810', 'https://openalex.org/W2128008175', 'https://openalex.org/W2128163368', 'https://openalex.org/W2129316761', 'https://openalex.org/W2129917779', 'https://openalex.org/W2132693319', 'https://openalex.org/W2134007048', 'https://openalex.org/W2139206194', 'https://openalex.org/W2140637559', 'https://openalex.org/W2142179862', 'https://openalex.org/W2143102054', 'https://openalex.org/W2144002476', 'https://openalex.org/W2144651868', 'https://openalex.org/W2148795627', 'https://openalex.org/W2149515881', 'https://openalex.org/W2149605526', 'https://openalex.org/W2150367899', 'https://openalex.org/W2150637250', 'https://openalex.org/W2150702412', 'https://openalex.org/W2151938344', 'https://openalex.org/W2152103960', 'https://openalex.org/W2156120317', 'https://openalex.org/W2156306286', 'https://openalex.org/W2156642970', 'https://openalex.org/W2158758822', 'https://openalex.org/W2161327673', 'https://openalex.org/W2162295519', 'https://openalex.org/W2162805222', 'https://openalex.org/W2163337422', 'https://openalex.org/W2165186407', 'https://openalex.org/W2167915346', 'https://openalex.org/W2170936782', 'https://openalex.org/W4211254511', 'https://openalex.org/W4240175730', 'https://openalex.org/W4242514389', 'https://openalex.org/W4249727000'], 'related_works': ['https://openalex.org/W3144262249', 'https://openalex.org/W3126045662', 'https://openalex.org/W2883561311', 'https://openalex.org/W2775971119', 'https://openalex.org/W2325011763', 'https://openalex.org/W2291436232', 'https://openalex.org/W2164406361', 'https://openalex.org/W2103200355', 'https://openalex.org/W2076063079', 'https://openalex.org/W2014030899'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1561041814', 'counts_by_year': [{'year': 2024, 'cited_by_count': 334}, {'year': 2023, 'cited_by_count': 337}, {'year': 2022, 'cited_by_count': 374}, {'year': 2021, 'cited_by_count': 375}, {'year': 2020, 'cited_by_count': 336}, {'year': 2019, 'cited_by_count': 262}, {'year': 2018, 'cited_by_count': 280}, {'year': 2017, 'cited_by_count': 262}, {'year': 2016, 'cited_by_count': 153}, {'year': 2015, 'cited_by_count': 29}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-08T13:14:07.784016', 'created_date': '2016-06-24'}