Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1557194500', 'doi': 'https://doi.org/10.2144/03351bm03', 'title': 'Identification and correction of spurious spatial correlations in microarray data', 'display_name': 'Identification and correction of spurious spatial correlations in microarray data', 'publication_year': 2003, 'publication_date': '2003-07-01', 'ids': {'openalex': 'https://openalex.org/W1557194500', 'doi': 'https://doi.org/10.2144/03351bm03', 'mag': '1557194500', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12866403'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2144/03351bm03', 'pdf_url': 'https://www.future-science.com/doi/pdf/10.2144/03351bm03', 'source': {'id': 'https://openalex.org/S79990748', 'display_name': 'BioTechniques', 'issn_l': '0736-6205', 'issn': ['0736-6205', '1940-9818'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320316', 'host_organization_name': 'Future Science Ltd', 'host_organization_lineage': ['https://openalex.org/P4310320316'], 'host_organization_lineage_names': ['Future Science Ltd'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.future-science.com/doi/pdf/10.2144/03351bm03', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100610506', 'display_name': 'Jiang Qian', 'orcid': 'https://orcid.org/0000-0002-0476-3596'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jiang Qian', 'raw_affiliation_strings': ['Yale University, New Haven, CT, USA'], 'affiliations': [{'raw_affiliation_string': 'Yale University, New Haven, CT, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020473435', 'display_name': 'Yuval Kluger', 'orcid': 'https://orcid.org/0000-0002-3035-071X'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yuval Kluger', 'raw_affiliation_strings': ['Yale University, New Haven, CT, USA'], 'affiliations': [{'raw_affiliation_string': 'Yale University, New Haven, CT, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067174340', 'display_name': 'Haiyuan Yu', 'orcid': 'https://orcid.org/0000-0001-7597-6049'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Haiyuan Yu', 'raw_affiliation_strings': ['Yale University, New Haven, CT, USA'], 'affiliations': [{'raw_affiliation_string': 'Yale University, New Haven, CT, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5042321575', 'display_name': 'Mark Gerstein', 'orcid': 'https://orcid.org/0000-0002-9746-3719'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mark Gerstein', 'raw_affiliation_strings': ['Yale University, New Haven, CT, USA'], 'affiliations': [{'raw_affiliation_string': 'Yale University, New Haven, CT, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1415, 'currency': 'USD', 'value_usd': 1415, 'provenance': 'doaj'}, 'apc_paid': {'value': 1415, 'currency': 'USD', 'value_usd': 1415, 'provenance': 'doaj'}, 'fwci': 1.872, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.705393, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '35', 'issue': '1', 'first_page': '42', 'last_page': '48'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10885', 'display_name': 'Microarray Data Analysis and Gene Expression Profiling', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10885', 'display_name': 'Microarray Data Analysis and Gene Expression Profiling', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11289', 'display_name': 'Comprehensive Integration of Single-Cell Transcriptomic Data', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10887', 'display_name': 'Analysis of Gene Interaction Networks', 'score': 0.9826, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/spatial-profiling', 'display_name': 'Spatial Profiling', 'score': 0.552156}, {'id': 'https://openalex.org/keywords/haven', 'display_name': 'Haven', 'score': 0.5424917}, {'id': 'https://openalex.org/keywords/microarray', 'display_name': 'Microarray', 'score': 0.523703}, {'id': 'https://openalex.org/keywords/lineage-tracking', 'display_name': 'Lineage Tracking', 'score': 0.515108}, {'id': 'https://openalex.org/keywords/clustering', 'display_name': 'Clustering', 'score': 0.505388}, {'id': 'https://openalex.org/keywords/feature-selection', 'display_name': 'Feature Selection', 'score': 0.500287}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5732105}, {'id': 'https://openalex.org/C2778217808', 'wikidata': 'https://www.wikidata.org/wiki/Q5683658', 'display_name': 'Haven', 'level': 2, 'score': 0.5424917}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.5421013}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.3322624}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.13245416}, {'id': 'https://openalex.org/C114614502', 'wikidata': 'https://www.wikidata.org/wiki/Q76592', 'display_name': 'Combinatorics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016477', 'descriptor_name': 'Artifacts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019544', 'descriptor_name': 'Equipment Failure Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': True}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': True}, {'descriptor_ui': 'D002138', 'descriptor_name': 'Calibration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011786', 'descriptor_name': 'Quality Control', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018401', 'descriptor_name': 'Sample Size', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013223', 'descriptor_name': 'Statistics as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.2144/03351bm03', 'pdf_url': 'https://www.future-science.com/doi/pdf/10.2144/03351bm03', 'source': {'id': 'https://openalex.org/S79990748', 'display_name': 'BioTechniques', 'issn_l': '0736-6205', 'issn': ['0736-6205', '1940-9818'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320316', 'host_organization_name': 'Future Science Ltd', 'host_organization_lineage': ['https://openalex.org/P4310320316'], 'host_organization_lineage_names': ['Future Science Ltd'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/063e46d42d62474ab49b81e42a570b0a', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12866403', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2144/03351bm03', 'pdf_url': 'https://www.future-science.com/doi/pdf/10.2144/03351bm03', 'source': {'id': 'https://openalex.org/S79990748', 'display_name': 'BioTechniques', 'issn_l': '0736-6205', 'issn': ['0736-6205', '1940-9818'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320316', 'host_organization_name': 'Future Science Ltd', 'host_organization_lineage': ['https://openalex.org/P4310320316'], 'host_organization_lineage_names': ['Future Science Ltd'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W1498862674', 'https://openalex.org/W1650504959', 'https://openalex.org/W1976208596', 'https://openalex.org/W1989297334', 'https://openalex.org/W2032510252', 'https://openalex.org/W2050883504', 'https://openalex.org/W2095958385', 'https://openalex.org/W2099114361', 'https://openalex.org/W2100668965', 'https://openalex.org/W2103453943', 'https://openalex.org/W2104292638', 'https://openalex.org/W2110153755', 'https://openalex.org/W2118659478', 'https://openalex.org/W2135000328', 'https://openalex.org/W2135187880', 'https://openalex.org/W2141407136', 'https://openalex.org/W2144227498', 'https://openalex.org/W2148541040', 'https://openalex.org/W2150926065', 'https://openalex.org/W2165011536', 'https://openalex.org/W2611831635'], 'related_works': ['https://openalex.org/W2788277189', 'https://openalex.org/W2130076355', 'https://openalex.org/W2119695867', 'https://openalex.org/W2117258802', 'https://openalex.org/W2082860237', 'https://openalex.org/W2046158694', 'https://openalex.org/W2013243191', 'https://openalex.org/W1993764875', 'https://openalex.org/W1990804418', 'https://openalex.org/W1971568933'], 'abstract_inverted_index': {'BioTechniquesVol.': [0], '35,': [1, 378], 'No.': [2, 114, 133, 153, 175, 185, 207, 227, 243, 263, 296, 312, 334, 352, 370, 375, 379], '1': [3, 376, 380], 'BenchmarksOpen': [4], 'AccessIdentification': [5], 'and': [6, 89, 143, 156, 197, 209, 222, 231, 272, 283, 357], 'correction': [7], 'of': [8, 96, 168, 188, 202, 212, 219, 281, 292, 301, 317, 337], 'spurious': [9], 'spatial': [10], 'correlations': [11, 121], 'in': [12, 122, 149, 163, 190, 278, 298, 308, 343, 401], 'microarray': [13, 233, 321, 361], 'dataJiang': [14], 'Qian,': [15], 'Yuval': [16, 29], 'Kluger,': [17], 'Haiyuan': [18, 36], 'Yu': [19], '&': [20, 43, 110], 'Mark': [21, 44, 48], 'GersteinJiang': [22], 'QianYale': [23], 'University,': [24, 31, 38, 58, 68], 'New': [25, 32, 39, 59, 69], 'Haven,': [26, 33, 40, 60, 70], 'CT,': [27, 34, 41, 71], 'USA,': [28, 35], 'KlugerYale': [30], 'YuYale': [37], 'USA': [42], 'Gerstein*Address': [45], 'correspondence': [46], 'to': [47, 77, 102, 270], 'Gerstein,': [49], 'MB&B': [50], 'Department,': [51], 'Bass': [52], '432A,': [53], '266': [54], 'Whitney': [55], 'Avenue,': [56], 'Yale': [57], 'CT': [61], '06520,': [62], 'USA.': [63], 'e-mail:': [64], 'E-mail': [65], 'Address:': [66], '[email protected]': [67], 'USAPublished': [72], 'Online:24': [73], 'Sep': [74], '2018https://doi.org/10.2144/03351bm03AboutSectionsPDF/EPUB': [75], 'ToolsAdd': [76], 'favoritesDownload': [78], 'CitationsTrack': [79], 'Citations': [80], 'ShareShare': [81], 'onFacebookTwitterLinkedInReddit': [82], 'FiguresReferencesRelatedDetailsCited': [83], 'ByThe': [84], 'Interplay': [85], 'Between': [86], 'the': [87, 169, 216, 279, 299, 314, 387], 'Transcriptomics': [88], 'Proteomics': [90], 'Profiles8': [91], 'March': [92, 126, 236], '2022PU.1': [93], 'drives': [94], 'specification': [95], 'pluripotent': [97], 'stem': [98], 'cell-derived': [99], 'endothelial': [100], 'cells': [101], 'LSEC-like': [103], 'cells14': [104], 'January': [105, 288], '2021': [106], '|': [107, 128, 147, 238, 258, 290, 329, 347, 365], 'Cell': [108], 'Death': [109], 'Disease,': [111], 'Vol.': [112, 131, 151, 173, 183, 205, 225, 241, 261, 294, 310, 332, 350, 368, 373, 377], '12,': [113, 206], '1Prokaryotic': [115], 'Systems': [116], 'Biology24': [117], 'April': [118], '2018Correcting': [119], 'positional': [120], 'Affymetrix®': [123], 'Genome': [124, 348], 'Chips13': [125], '2015': [127], 'Scientific': [129], 'Reports,': [130], '5,': [132, 333], '1Reverse': [134], 'engineering': [135], 'biomolecular': [136], 'systems': [137], 'using': [138, 323], '-omic': [139], 'data:': [140], 'challenges,': [141], 'progress': [142], 'opportunities25': [144], 'July': [145, 403], '2012': [146], 'Briefings': [148], 'Bioinformatics,': [150, 240, 260], '13,': [152], '4ML': [154], 'estimation': [155], 'an': [157], 'efficiency': [158], 'study': [159], 'for': [160, 178, 250, 305, 339, 386], 'mean': [161], 'estimators': [162], 'spatially': [164], 'correlated': [165], 'repeated': [166], 'arraysJournal': [167], 'Korean': [170], 'Statistical': [171], 'Society,': [172], '38,': [174], '1Quality': [176], 'Assessment': [177], 'Short': [179], 'Oligonucleotide': [180], 'Microarray': [181, 268, 274], 'DataTechnometrics,': [182], '50,': [184], '3Characterizing': [186], 'Regulation': [187], 'Metabolism': [189], 'Geobacter': [191], 'sulfurreducens': [192], 'through': [193], 'Genome-Wide': [194], 'Expression': [195], 'Data': [196], 'Sequence': [198], 'AnalysisOMICS:': [199], 'A': [200], 'Journal': [201, 291], 'Integrative': [203], 'Biology,': [204], '1Genotypic': [208], 'Physiological': [210], 'Characterization': [211], 'Saccharomyces': [213, 220], 'boulardii': [214], ',': [215], 'Probiotic': [217], 'Strain': [218], 'cerevisiaeApplied': [221], 'Environmental': [223], 'Microbiology,': [224], '73,': [226], '8SimArray:': [228], 'a': [229], 'user-friendly': [230], 'user-configurable': [232], 'design': [234], 'tool1': [235], '2006': [237, 257], 'BMC': [239, 259, 330, 366], '7,': [242, 262], '1Rank-statistics': [244], 'based': [245], 'enrichment-site': [246], 'prediction': [247], 'algorithm': [248], 'developed': [249], 'chromatin': [251], 'immunoprecipitation': [252], 'on': [253, 360, 383], 'chip': [254], 'experiments5': [255], 'October': [256], '1[15]': [264], 'Extrapolating': [265], 'Traditional': [266], 'DNA': [267], 'Statistics': [269], 'Tiling': [271], 'Protein': [273], 'TechnologiesEnhanced': [275], 'gene': [276, 355], 'expression': [277], 'forebrain': [280], 'hatchling': [282], 'juvenile': [284], 'male': [285], 'zebra': [286], 'finches1': [287], '2005': [289], 'Neurobiology,': [293], '64,': [295], '2Issues': [297], 'analysis': [300], 'oligonucleotide': [302], 'tiling': [303], 'microarrays': [304], 'transcript': [306], 'mappingTrends': [307], 'Genetics,': [309], '21,': [311], '8Improving': [313], 'statistical': [315], 'detection': [316], 'regulated': [318], 'genes': [319], 'from': [320], 'data': [322], 'intensity-based': [324], 'variance': [325], 'estimation27': [326], 'February': [327], '2004': [328, 346], 'Genomics,': [331, 367], '1The': [335], 'Use': [336], 'MPSS': [338], 'Whole-Genome': [340], 'Transcriptional': [341], 'Analysis': [342], 'Arabidopsis2': [344], 'August': [345], 'Research,': [349], '14,': [351], '8Relationship': [353], 'between': [354], 'co-expression': [356], 'probe': [358], 'localization': [359], 'slides10': [362], 'December': [363], '2003': [364, 404], '4,': [369], '1Molecular': [371], 'DiagnosticsHematology,': [372], '2003,': [374], 'Follow': [381], 'us': [382], 'social': [384], 'media': [385], 'latest': [388], 'updates': [389], 'Metrics': [390], 'Downloaded': [391], '143': [392], 'times': [393], 'History': [394], 'Published': [395, 400], 'online': [396], '24': [397], 'September': [398], '2018': [399, 406], 'print': [402], 'Information©': [405], 'Author(s)PDF': [407], 'download': [408]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1557194500', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-15T02:46:44.654843', 'created_date': '2016-06-24'}