Publication Information

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'https://openalex.org/W2006528422', 'https://openalex.org/W1993538553', 'https://openalex.org/W1978558050', 'https://openalex.org/W1977827629'], 'abstract_inverted_index': {'Neuronal': [0], 'function,': [1], 'survival': [2], 'and': [3, 36, 80, 84, 135, 217, 220, 261, 396, 487, 498, 523, 550, 584, 689, 769, 789, 803, 809, 837, 867, 896, 923, 965], 'architecture': [4], 'all': [5], 'critically': [6], 'depend': [7], 'on': [8], 'the': [9, 48, 72, 86, 93, 103, 142, 154, 191, 197, 272, 306, 316, 392, 394, 397, 446, 464, 469, 500, 505, 542, 559, 598, 618, 622, 646, 662, 714, 774, 801, 827], 'precise': [10], 'transport': [11, 24, 42, 58, 76, 87, 105, 115, 128, 146, 155, 260, 432, 440, 776, 861, 918], 'of': [12, 19, 51, 74, 88, 95, 107, 144, 157, 172, 193, 199, 227, 271, 297, 308, 319, 330, 368, 399, 438, 468, 507, 544, 561, 600, 624, 632, 653, 664, 716, 722, 727, 805, 829], 'intracellular': [13, 23], 'proteins': [14], 'to': [15, 26, 62, 77, 85, 101, 111, 124, 136, 147, 166, 325, 348, 363, 441, 528, 577, 585, 678, 691, 763, 858, 872, 884, 892, 897, 915, 924, 942, 951, 961], 'a': [16, 163, 168, 184, 215, 295, 302, 349, 366, 442, 534, 555, 629, 637, 643, 651, 658, 710, 794, 819, 845, 939], 'vast': [17], 'array': [18], 'synaptic': [20, 29, 109, 159, 175, 185, 194, 492, 811, 955], 'connections.': [21, 812], 'Disrupted': [22], 'leads': [25], 'deficits': [27, 43, 59, 129, 772], 'in': [28, 47, 121, 131, 196, 214, 258, 292, 305, 352, 388, 473, 497, 541, 558, 597, 621, 628, 645, 661, 671, 681, 713, 731, 740, 773, 841, 856, 863, 881, 906, 920], 'transmission,': [30], 'irregular': [31], 'cell': [32, 37, 150, 465, 782, 807, 822, 839, 876], 'morphology,': [33], 'misallocated': [34], 'organelles': [35], 'death.': [38], 'In': [39, 341], 'addition,': [40, 342], 'axonal': [41, 57, 75, 444], 'have': [44], 'been': [45], 'noted': [46], 'early': [49], 'stages': [50], 'several': [52], 'debilitating': [53], 'neurological': [54], 'conditions,': [55], 'thus,': [56], 'may': [60, 416, 604, 770], 'contribute': [61], 'disease': [63, 133], 'progression.': [64], 'This': [65, 410, 478, 595, 798], 'makes': [66], 'it': [67, 746, 912], 'important': [68, 607], 'that': [69, 212, 223, 412, 530, 755, 874, 886, 900, 935], 'we': [70, 161, 188, 265, 300, 434, 525, 615, 656, 817], 'understand': [71], 'contribution': [73], 'both': [78, 484, 787, 800, 962], 'physiological': [79], 'pathophysiological': [81, 608], 'cellular': [82, 796], 'processes': [83], 'essential': [89], 'organelles.': [90], '\r\n\r\nAs': [91], 'such': [92], 'aims': [94], 'this': [96, 815, 910, 936], 'project': [97], 'were': [98, 242, 249, 382, 495, 526, 870], 'as': [99, 183, 365], 'follows:': [100], 'investigate': [102, 112, 153, 254, 925], 'long-term': [104], 'properties': [106, 156], 'visualised': [108, 158], 'vesicles,': [110], 'whether': [113, 126], 'vesicle': [114, 127, 145, 176, 186, 208, 235, 247, 251, 259, 262, 311, 320, 353, 389, 414, 431, 439, 454, 508, 546, 563, 602, 626, 666, 718, 729, 775, 860, 901, 917, 926], 'could': [116, 878], 'be': [117, 418, 879, 949], 'modulated': [118, 420], 'by': [119, 385, 404, 421, 611, 642], 'changes': [120, 257, 381, 433], 'neuronal': [122, 149, 287, 332, 344, 370, 406, 423], 'activity,': [123], 'examine': [125], 'exist': [130], 'certain': [132], 'models': [134, 636], 'develop': [137], 'novel': [138], 'assays': [139], 'for': [140, 428, 825], 'focusing': [141], 'study': [143, 437, 804], 'specific': [148, 443, 806, 810, 875], 'types.': [151], '\r\n\r\nTo': [152, 425], 'vesicles': [160, 195, 229, 241, 482], 'exploited': [162], 'lentiviral': [164, 887], 'vector': [165], 'express': [167], 'fluorescently': [169], 'tagged': [170], 'version': [171], 'an': [173, 606], 'abundant': [174], 'transmembrane': [177], 'protein,': [178], 'synaptophysin.': [179], 'Using': [180, 909], 'synaptophysin-GFP': [181], '(syp-GFP)': [182], 'marker': [187], 'then': [189], 'tracked': [190], 'movements': [192], 'axons': [198], 'dissociated': [200, 780, 821, 830, 946], 'hippocampal': [201, 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289, 516], 'co-culture': [269], 'application': [270], 'GABAA': [273], 'receptor': [274], 'antagonists': [275], 'bicuculline': [276], '(bic)': [277], '(20µM)': [278], 'Gabazine': [280], '(gbz)': [281], '(20µM),': [282], 'which': [283, 356, 494, 635], 'can': [284, 948], 'generate': [285], 'increased': [286, 331, 343, 357, 369, 405, 422], 'activity': [288, 291, 333, 345, 371, 407, 532, 765], 'epileptiform-like': [290], 'vitro.': [293], 'As': [294, 650], 'result': [296, 367], 'bic': [298, 517, 566, 654, 683, 694, 723, 733, 742], 'treatment': [299, 518, 655], 'observed': [301, 617, 657], 'significant': [303, 350, 539, 556, 659, 940], 'decrease': [304, 540, 557, 596, 620, 660, 712], 'size': [307, 318], 'Under': [313], 'control': [314, 361, 572, 672], 'conditions': [315, 362, 573], 'average': [317], '14.7±1.67µm2,': [323], 'reducing': [324], '12.1±1.41µm2': [326], 'following': [327, 514, 565, 693, 720], '10': [328], 'hours': [329, 552], '(p=0.0042,': [334], 'Wilcoxon-matched': [335], 'pairs': 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