Publication Information

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'https://openalex.org/W1831449886'], 'abstract_inverted_index': {'AIM:': [0], 'To': [1], 'study': [2], 'the': [3, 51, 73, 104, 111, 134, 137, 170], 'effects': [4], 'of': [5, 11, 28, 41, 55, 82, 101, 106, 115, 125, 133, 156, 167], 'actinomycin': [6, 78, 126], 'D': [7, 79, 153], 'on': [8], 'subcellular': [9, 39], 'distribution': [10, 40], 'nucleolar': [12, 66], 'protein': [13], 'fibrillarin': [14, 29, 43, 71, 83, 102, 107, 116, 157, 168], 'in': [15, 30, 162], 'HEp-2': [16, 163], '(human': [17], 'esophageal': [18], 'epithelial': [19], 'type': [20], '2)': [21], 'cells,': [22], 'and': [23, 44], 'molecular': [24], 'mechanisms': [25], 'for': [26], 'maintenance': [27], 'nucleolus.METHODS:': [31], 'Indirect': [32], 'immunofluorescence': [33], 'assay': [34], 'was': [35, 47, 108, 128, 142, 172], 'employed': [36], 'to': [37, 49, 86, 160, 174], 'investigate': [38], 'nucleolarprotein': [42], 'immunoblotting': [45], 'analysis': [46], 'used': [48], 'detect': [50], 'total': [52, 98], 'cellular': [53, 99], 'amount': [54, 100], 'fibrillarin.': [56], 'RESULTS:Control': [57], 'cells': [58], 'with': [59, 77, 88], 'no': [60], 'drug': [61, 135, 148], 'treatment': [62], 'showed': [63, 95], 'bright': [64], 'clumpy': [65], 'staining,': [67], 'which': [68], 'indicated': [69], 'that': [70, 96], 'decorated': [72], 'nucleolus': [74, 171], 'only.': [75], 'Treatment': [76], 'caused': [80], 'dislocation': [81, 114, 155], 'from': [84, 136, 158], 'nucleoli': [85, 159], 'nucleoplasm': [87, 161], 'numerous': [89], 'stained': [90], 'small': [91], 'nucleoplasmic': [92], 'entities.': [93], 'Immunoblotting': [94], 'neither': [97], 'nor': [103], 'integrity': [105], 'changed': [109], 'upon': [110], 'treatment.': [112], 'The': [113, 165], 'incells': [117], 'treated': [118], 'at': [119, 145], 'a': [120, 146], 'lower': [121], 'concentration': [122, 149], '(0.05': [123], 'mg/L)': [124], 'D,': [127], 'totally': [129], 'reversible': [130], 'after': [131], 'removal': [132], 'medium.': [138], 'However,': [139], 'this': [140], 'reversion': [141], 'not': [143], 'observed': [144], 'high': [147], '(1': [150], 'mg/L).': [151], 'CONCLUSION:Actinomycin': [152], 'induced': [154], 'cells.': [164], 'retention': [166], 'within': [169], 'related': [173], 'active': [175], 'RNA': [176], 'synthesis.': [177]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1533630503', 'counts_by_year': [], 'updated_date': '2024-12-08T02:35:58.890194', 'created_date': '2016-06-24'}