Title: 924. Gene Therapy with IGF-1 Growth Factor for Heart Failure
Abstract:Congestive heart failure (CHF) remains a significant therapeutic challenge. Efficacious therapies are few, and the incidence of CHF and associated death rates continue to rise. Interest in gene therap...Congestive heart failure (CHF) remains a significant therapeutic challenge. Efficacious therapies are few, and the incidence of CHF and associated death rates continue to rise. Interest in gene therapy for CHF can be directed towards preserving cardiomyocyte structure and improving its function. Beneficial cardiac effects of growth hormone and insulin-like growth factor-1 (IGF-1) have been shown in heart failure in several settings, but studies are lacking on such forms of treatment in the cardiomyopathic heart.Read More