Publication Information

{'id': 'https://openalex.org/W1516948452', 'doi': 'https://doi.org/10.1111/j.1469-1809.2010.00623.x', 'title': 'Importance Measures for Epistatic Interactions in Case-Parent Trios', 'display_name': 'Importance Measures for Epistatic Interactions in Case-Parent Trios', 'publication_year': 2010, 'publication_date': '2010-11-30', 'ids': {'openalex': 'https://openalex.org/W1516948452', 'doi': 'https://doi.org/10.1111/j.1469-1809.2010.00623.x', 'mag': '1516948452', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21118192', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3059247'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1469-1809.2010.00623.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S131700781', 'display_name': 'Annals of Human Genetics', 'issn_l': '0003-4800', 'issn': ['0003-4800', '1469-1809'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://doi.org/10.1111/j.1469-1809.2010.00623.x', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5037974033', 'display_name': 'Holger Schwender', 'orcid': 'https://orcid.org/0000-0002-2858-6715'}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Holger Schwender', 'raw_affiliation_strings': ['Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA', 'institution_ids': ['https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087632400', 'display_name': 'Katherine Bowers', 'orcid': 'https://orcid.org/0000-0001-5085-5208'}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Katherine Bowers', 'raw_affiliation_strings': ['Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA', 'institution_ids': ['https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002407483', 'display_name': 'M. Daniele Fallin', 'orcid': 'https://orcid.org/0000-0002-9948-3908'}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Daniele Fallin', 'raw_affiliation_strings': ['Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA', 'institution_ids': ['https://openalex.org/I145311948']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086448897', 'display_name': 'Ingo Ruczinski', 'orcid': 'https://orcid.org/0000-0003-3278-6274'}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ingo Ruczinski', 'raw_affiliation_strings': ['Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA', 'institution_ids': ['https://openalex.org/I145311948']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3040, 'currency': 'USD', 'value_usd': 3040, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.534, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.713377, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '75', 'issue': '1', 'first_page': '122', 'last_page': '132'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10261', 'display_name': 'Genetic Associations and Epidemiology', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10261', 'display_name': 'Genetic Associations and Epidemiology', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10885', 'display_name': 'Gene expression and cancer classification', 'score': 0.9845, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10887', 'display_name': 'Bioinformatics and Genomic Networks', 'score': 0.9601, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/linkage-disequilibrium', 'display_name': 'Linkage Disequilibrium', 'score': 0.6605989}, {'id': 'https://openalex.org/keywords/epistasis', 'display_name': 'Epistasis', 'score': 0.6294065}, {'id': 'https://openalex.org/keywords/linkage', 'display_name': 'Linkage (software)', 'score': 0.46308762}], 'concepts': [{'id': 'https://openalex.org/C35605836', 'wikidata': 'https://www.wikidata.org/wiki/Q2064311', 'display_name': 'Linkage disequilibrium', 'level': 5, 'score': 0.6605989}, {'id': 'https://openalex.org/C61727976', 'wikidata': 'https://www.wikidata.org/wiki/Q751748', 'display_name': 'Epistasis', 'level': 3, 'score': 0.6294065}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.53788584}, {'id': 'https://openalex.org/C2780009758', 'wikidata': 'https://www.wikidata.org/wiki/Q6804172', 'display_name': 'Measure (data warehouse)', 'level': 2, 'score': 0.52697015}, {'id': 'https://openalex.org/C153209595', 'wikidata': 'https://www.wikidata.org/wiki/Q501128', 'display_name': 'Single-nucleotide polymorphism', 'level': 4, 'score': 0.46962622}, {'id': 'https://openalex.org/C31266012', 'wikidata': 'https://www.wikidata.org/wiki/Q6554340', 'display_name': 'Linkage (software)', 'level': 3, 'score': 0.46308762}, {'id': 'https://openalex.org/C169258074', 'wikidata': 'https://www.wikidata.org/wiki/Q245748', 'display_name': 'Random forest', 'level': 2, 'score': 0.4380918}, {'id': 'https://openalex.org/C154945302', 'wikidata': 'https://www.wikidata.org/wiki/Q11660', 'display_name': 'Artificial intelligence', 'level': 1, 'score': 0.4080655}, {'id': 'https://openalex.org/C119857082', 'wikidata': 'https://www.wikidata.org/wiki/Q2539', 'display_name': 'Machine learning', 'level': 1, 'score': 0.39770126}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.32404906}, {'id': 'https://openalex.org/C124101348', 'wikidata': 'https://www.wikidata.org/wiki/Q172491', 'display_name': 'Data mining', 'level': 1, 'score': 0.28877726}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.27809155}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.116416276}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001321', 'descriptor_name': 'Autistic Disorder', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004843', 'descriptor_name': 'Epistasis, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020641', 'descriptor_name': 'Polymorphism, Single Nucleotide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001321', 'descriptor_name': 'Autistic Disorder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016022', 'descriptor_name': 'Case-Control Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005190', 'descriptor_name': 'Family', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015810', 'descriptor_name': 'Linkage Disequilibrium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008957', 'descriptor_name': 'Models, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1469-1809.2010.00623.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S131700781', 'display_name': 'Annals of Human Genetics', 'issn_l': '0003-4800', 'issn': ['0003-4800', '1469-1809'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3059247', 'pdf_url': 'https://europepmc.org/articles/pmc3059247?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059247', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21118192', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1469-1809.2010.00623.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S131700781', 'display_name': 'Annals of Human Genetics', 'issn_l': '0003-4800', 'issn': ['0003-4800', '1469-1809'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.61, 'id': 'https://metadata.un.org/sdg/15', 'display_name': 'Life on land'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 64, 'referenced_works': ['https://openalex.org/W120229385', 'https://openalex.org/W1539593569', 'https://openalex.org/W1594031697', 'https://openalex.org/W1786104672', 'https://openalex.org/W1966315117', 'https://openalex.org/W1968673914', 'https://openalex.org/W1980175560', 'https://openalex.org/W1986858673', 'https://openalex.org/W1989194097', 'https://openalex.org/W1992426043', 'https://openalex.org/W1993537263', 'https://openalex.org/W1993856301', 'https://openalex.org/W2004159986', 'https://openalex.org/W2009969871', 'https://openalex.org/W2016960965', 'https://openalex.org/W2018188045', 'https://openalex.org/W2035189108', 'https://openalex.org/W2037827636', 'https://openalex.org/W2043134049', 'https://openalex.org/W2043192290', 'https://openalex.org/W2049147602', 'https://openalex.org/W2050063758', 'https://openalex.org/W2052182252', 'https://openalex.org/W2057473493', 'https://openalex.org/W2060595345', 'https://openalex.org/W2063318748', 'https://openalex.org/W2064429529', 'https://openalex.org/W2074099509', 'https://openalex.org/W2083944388', 'https://openalex.org/W2086099578', 'https://openalex.org/W2086934780', 'https://openalex.org/W2090548245', 'https://openalex.org/W2091032435', 'https://openalex.org/W2091548875', 'https://openalex.org/W2094879249', 'https://openalex.org/W2097364929', 'https://openalex.org/W2101791172', 'https://openalex.org/W2104059095', 'https://openalex.org/W2106233199', 'https://openalex.org/W2107659056', 'https://openalex.org/W2109353557', 'https://openalex.org/W2114740540', 'https://openalex.org/W2131878646', 'https://openalex.org/W2133298971', 'https://openalex.org/W2143865774', 'https://openalex.org/W2149654513', 'https://openalex.org/W2151920593', 'https://openalex.org/W2154572047', 'https://openalex.org/W2158115943', 'https://openalex.org/W2160697532', 'https://openalex.org/W2161398339', 'https://openalex.org/W2163393712', 'https://openalex.org/W2165587740', 'https://openalex.org/W2166503668', 'https://openalex.org/W2171558600', 'https://openalex.org/W2172136348', 'https://openalex.org/W2404945087', 'https://openalex.org/W2911964244', 'https://openalex.org/W2912934387', 'https://openalex.org/W3085162807', 'https://openalex.org/W4212883601', 'https://openalex.org/W4231211138', 'https://openalex.org/W4231980339', 'https://openalex.org/W4244313837'], 'related_works': ['https://openalex.org/W4361273069', 'https://openalex.org/W2473486371', 'https://openalex.org/W2410452464', 'https://openalex.org/W2391803837', 'https://openalex.org/W2102796473', 'https://openalex.org/W2093214227', 'https://openalex.org/W2069461486', 'https://openalex.org/W2043540174', 'https://openalex.org/W2039373331', 'https://openalex.org/W2033454892'], 'abstract_inverted_index': {'Annals': [0], 'of': [1, 22, 28, 45, 51, 70, 76, 95, 101, 113, 119, 154, 160, 177, 183, 202, 208, 227, 233, 245, 251, 310, 320, 333, 344, 366, 380, 401, 407, 414, 432, 439, 442, 456, 490, 502, 693, 831, 866, 926, 965, 1009, 1059, 1201, 1282, 1357, 1403, 1593, 1598, 1621, 1639, 1662, 1813, 1822, 1890, 1972, 1995, 2006, 2079, 2090, 2095, 2135, 2155, 2194, 2210, 2232, 2365, 2372, 2420, 2442], 'Human': [2], 'GeneticsVolume': [3], '75,': [4], 'Issue': [5], '1': [6, 881], 'p.': [7], '122-132': [8, 2458], 'Importance': [9], 'Measures': [10], 'for': [11, 35, 58, 83, 143, 167, 190, 215, 275, 384, 396, 436, 459, 829, 861, 962, 1087, 1159, 1198, 1304, 1395, 1546, 1718, 1779, 1846, 1900, 1933, 1999, 2153, 2177, 2234, 2363, 2415], 'Epistatic': [12], 'Interactions': [13], 'in': [14, 423, 484, 494, 498, 770, 796, 822, 879, 1005, 1062, 1405, 1596, 1624, 1753, 1818, 2003, 2050, 2093, 2129, 2236, 2327, 2334, 2424], 'Case-Parent': [15], 'Trios': [16], 'Holger': [17, 19, 149, 151], 'Schwender,': [18, 150, 1961, 2203, 2220], 'Schwender': [20, 152], 'Department': [21, 44, 69, 94, 112, 153, 176, 201, 226, 244], 'Biostatistics,': [23, 96, 114, 155, 228, 246, 2239], 'Johns': [24, 47, 72, 97, 115, 156, 179, 204, 229, 247], 'Hopkins': [25, 48, 73, 98, 116, 157, 180, 205, 230, 248], 'Bloomberg': [26, 49, 74, 99, 117, 158, 181, 206, 231, 249], 'School': [27, 50, 75, 100, 118, 159, 182, 207, 232, 250], 'Public': [29, 52, 77, 102, 120, 161, 184, 209, 234, 252], 'Health,': [30, 53, 78, 103, 121, 162, 185, 210, 235, 253], 'Baltimore,': [31, 54, 79, 104, 126, 163, 186, 211, 236, 258], 'MD': [32, 55, 80, 105, 127, 164, 187, 212, 237, 259], '21218,': [33, 56, 81, 106, 128, 165, 188, 213, 238, 260], 'USASearch': [34, 57, 82, 166, 189, 214], 'more': [36, 59, 84, 144, 168, 191, 216, 276], 'papers': [37, 60, 85, 145, 169, 192, 217, 277], 'by': [38, 61, 86, 146, 170, 193, 218, 278, 474, 1491], 'this': [39, 62, 87, 147, 171, 194, 219, 279, 345, 450], 'authorKatherine': [40, 172], 'Bowers,': [41, 173], 'Katherine': [42, 174], 'Bowers': [43, 175], 'Epidemiology,': [46, 71, 178, 203], 'authorM.': [63, 195], 'Daniele': [64, 67, 196, 199], 'Fallin,': [65, 197, 1563, 1613], 'M.': [66, 198, 514, 558, 588, 709, 736, 758, 792, 956, 996, 1048, 1052, 1108, 1268, 1293, 1341, 1375, 1482, 1522, 1564, 1614, 1658, 1735, 1770, 1774, 1984, 2021, 2062, 2108, 2125, 2187, 2242, 2250, 2390], 'Fallin': [68, 200], 'authorIngo': [88, 220], 'Ruczinski,': [89, 111, 221, 243, 1501, 1519, 1589, 1617, 2102, 2119, 2222], 'Corresponding': [90, 108, 222, 240], 'Author': [91, 223], 'Ingo': [92, 110, 224, 242], 'Ruczinski': [93, 225], 'USA': [107, 239, 727], 'author:': [109, 241], '615': [122, 254], 'N': [123, 255], 'Wolfe': [124, 256], 'Street,': [125, 257], 'USA.': [129, 261], 'Tel:': [130, 262], '+1': [131, 136, 263, 268], '410': [132, 137, 264, 269], '614': [133, 265], '7840;': [134, 266], 'Fax': [135, 267], '955': [138, 270], '0958;': [139, 271], 'E-mail:': [140, 272], '[email': [141, 273], 'protected]Search': [142, 274], 'author': [148, 280], 'First': [281], 'published:': [282], '30': [283], 'November': [284], '2010': [285], 'https://doi.org/10.1111/j.1469-1809.2010.00623.xCitations:': [286], '12Read': [287], 'the': [288, 326, 336, 415, 419, 437, 440, 446, 480, 488, 491, 863, 1006, 1199, 1466, 2004, 2178, 2328], 'full': [289, 300], 'textAboutPDF': [290], 'ToolsRequest': [291], 'permissionExport': [292], 'citationAdd': [293], 'to': [294, 316, 339, 374, 429, 445, 575, 717, 767, 877, 902, 973, 1399, 1407, 1749, 1944, 2256], 'favoritesTrack': [295], 'citation': [296], 'ShareShare': [297], 'Give': [298], 'accessShare': [299, 302], 'text': [301], 'full-text': [303, 318, 342], 'accessPlease': [304], 'review': [305], 'our': [306], 'Terms': [307, 330], 'and': [308, 312, 324, 331, 350, 361, 377, 417, 463, 497, 609, 650, 720, 833, 837, 840, 975, 1001, 1065, 1162, 1203, 1235, 1307, 1347, 1351, 1360, 1664, 1671, 1896, 1942, 2012, 2088, 2162, 2175, 2230, 2261, 2331, 2370, 2417, 2445], 'Conditions': [309, 332], 'Use': [311], 'check': [313], 'box': [314], 'below': [315, 338], 'share': [317, 340], 'version': [319, 343], 'article.I': [321], 'have': [322], 'read': [323], 'accept': [325], 'Wiley': [327], 'Online': [328], 'Library': [329], 'UseShareable': [334], 'LinkUse': [335], 'link': [337], 'a': [341, 499, 746, 869, 1088, 1939], 'article': [346], 'with': [347, 506, 579, 604, 971, 1064, 1278, 1354, 1550, 1600, 1904, 1949, 2138, 2158], 'your': [348], 'friends': [349], 'colleagues.': [351], 'Learn': [352, 622, 632], 'more.Copy': [353], 'URL': [354], 'Summary': [355], 'Ensemble': [356], 'methods': [357, 970], '(such': [358, 370], 'as': [359, 371, 391, 426, 1082], 'Bagging': [360, 619], 'Random': [362, 629, 696], 'Forests)': [363], 'take': [364], 'advantage': [365], 'unstable': [367], 'base': [368, 427], 'learners': [369, 428], 'decision': [372], 'trees)': [373], 'improve': [375, 1015], 'predictions,': [376], 'offer': [378], 'measures': [379], 'variable': [381, 385], 'importance': [382, 467, 2235], 'useful': [383], 'selection.': [386], 'LogicFS': [387, 410], 'has': [388], 'been': [389], 'proposed': [390], 'such': [392], 'an': [393, 454, 465, 1279], 'ensemble': [394], 'learner': [395], 'case-control': [397], 'studies': [398, 496, 578, 1821, 2094], 'when': [399], 'interactions': [400, 444, 900, 1234, 1595, 1623, 1699, 1817, 1971, 2002, 2046, 2092, 2128, 2212, 2326], 'single': [402, 1973, 2367], 'nucleotide': [403, 1974, 2368], 'polymorphisms': [404, 543, 867, 1947, 1975, 2369], '(SNPs)': [405], 'are': [406], 'particular': [408], 'interest.': [409], 'uses': [411], 'bootstrap': [412], 'samples': [413], 'data': [416, 2444], 'employs': [418], 'Boolean': [420], 'trees': [421, 2260], 'derived': [422], 'logic': [424, 1492, 1510, 1530, 2136, 2214], 'regression': [425, 651, 744, 859], 'create': [430], 'ensembles': [431], 'models': [433, 927], 'that': [434, 469, 1666, 1722], 'allow': [435], 'quantification': [438], 'contributions': [441], 'epistatic': [443, 899], 'disease': [447, 2159], 'risk.': [448], 'In': [449], 'article,': [451], 'we': [452], 'propose': [453], 'extension': [455], 'logicFS': [457], 'suitable': [458], 'case-parent': [460, 504, 1625], 'trio': [461], 'data,': [462, 2010], 'derive': [464], 'additional': [466], 'measure': [468, 481], 'is': [470], 'much': [471], 'less': [472], 'influenced': [473], 'linkage': [475, 1665], 'disequilibrium': [476], 'between': [477, 1893], 'SNPs': [478, 691, 1404, 1506, 2229, 2233], 'than': [479], 'originally': [482], 'used': [483], 'logicFS.': [485], 'We': [486], 'illustrate': [487], 'performance': [489], 'novel': [492, 1747], 'procedure': [493, 860], 'simulation': [495], 'case': [500], 'study': [501, 1200, 1696], '461': [503], 'trios': [505, 1597, 1626], 'autistic': [507], 'children.': [508, 1602], 'References': [509], 'Andrew,': [510, 1264], 'A.': [511, 643, 1051, 1137, 1265, 1586, 1922, 2289, 2438], 'S.,': [512, 520, 522, 524, 947, 984, 1035, 1111, 1127, 1224, 1251, 1254, 1266, 1426, 1428, 1478, 1538, 1579, 1801, 1878, 2069, 2346, 2385, 2388], 'Karagas,': [513, 1267], 'R.,': [515, 891, 911, 982, 1129, 1327, 1331, 1452, 1733, 1798, 1871, 1958, 2030, 2243, 2277, 2284, 2402, 2404], 'Nelson,': [516, 1255], 'H.': [517, 712, 810, 849, 1150, 1256, 1273, 1298, 1340, 1445, 1457, 1540, 1744, 1805, 1992, 2040, 2076, 2204, 2357], 'H.,': [518, 529, 640, 987, 1046, 1170, 1257, 1333, 1773, 1858, 1962, 2221], 'Guarrera,': [519], 'Polidoro,': [521], 'Gamberini,': [523], 'Sacerdote,': [525], 'C.,': [526, 1099, 1133, 1142, 1174, 1415, 1439, 1448, 1518, 1866, 2066, 2398], 'Moore,': [527, 1271, 1296, 1742, 1990, 2038, 2074], 'J.': [528, 565, 568, 595, 598, 639, 647, 814, 850, 916, 997, 1148, 1153, 1185, 1215, 1272, 1297, 1374, 1454, 1483, 1573, 1634, 1654, 1687, 1743, 1775, 1836, 1857, 1991, 2039, 2068, 2075, 2148, 2172, 2245, 2311, 2410, 2433], 'Kelsey,': [530, 1258], 'K.': [531, 678, 1259, 1344, 1583, 1648, 1681, 1806, 1832, 1833, 1854, 1964, 2207, 2226], 'T.,': [532, 707, 1123, 1222, 1260, 1323, 1338, 1430, 1450, 1960, 2296, 2316, 2352], 'Demidenko,': [533], 'E.,': [534, 1030, 1216, 1219], 'Vineis,': [535], 'P.': [536, 659, 684, 687, 986, 1034, 1578, 1630, 1691, 1710, 1918, 1925, 2312], '&': [537, 566, 596, 644, 660, 685, 710, 737, 759, 790, 815, 851, 894, 917, 954, 994, 1053, 1151, 1186, 1227, 1270, 1295, 1342, 1388, 1455, 1484, 1500, 1523, 1541, 1588, 1616, 1632, 1655, 1688, 1711, 1741, 1772, 1807, 1834, 1884, 1923, 1965, 1989, 2037, 2073, 2106, 2123, 2188, 2205, 2224, 2247, 2320, 2355, 2408, 2435], 'Matullo,': [538], 'G.': [539, 818, 854, 1371, 1921, 2406], '(2008)': [540, 763, 1345, 1458, 2191, 2208, 2324, 2412], 'DNA': [541], 'repair': [542], 'modify': [544], 'bladder': [545], 'cancer': [546, 1083, 1237, 1350], 'risk:': [547], 'A': [548, 571, 714, 800, 826, 856, 921, 959, 1196, 1366, 1461, 1746, 1783], 'multi-factor': [549], 'analytic': [550], 'strategy.': [551], 'Hum': [552, 582, 804, 885, 934, 1209, 1556, 1675, 1826, 1907, 1952, 2056], 'Hered': [553, 805, 1557, 1827], '65,': [554], '105–': [555], '118.': [556], 'Baksh,': [557, 587], 'F.,': [559, 589, 1131, 1419], 'Balding,': [560, 590], 'D.': [561, 591, 817, 853, 957, 992, 1104, 1169, 1253, 1294, 1386, 1615, 1767, 1771, 1809, 1837, 1865, 1877, 1886, 2147, 2171, 2246], 'J.,': [562, 592, 674, 811, 1102, 1119, 1138, 1172, 1178, 1319, 1708, 2309, 2313], 'Vyse,': [563, 593], 'T.': [564, 594, 683, 732, 754, 782, 893, 919, 940, 1567, 1611, 2190, 2292, 2295, 2354], 'Whittaker,': [567, 597], 'C.': [569, 599, 646, 706, 740, 762, 789, 989, 1041, 1229, 1230, 1250, 1381, 1423, 1486, 1499, 1714, 1800, 1926, 2105, 2122, 2273, 2283, 2407], '(2006)': [570, 1231, 1392, 1745, 1776], 'likelihood': [572], 'ratio': [573], 'approach': [574, 716, 1464, 2362], 'family-based': [576], 'association': [577, 602, 824, 1353, 1663, 1695, 1820, 2237], 'covariates.': [580], 'Ann': [581, 666, 1951], 'Genet': [583, 611, 698, 843, 886, 905, 935, 1210, 1411, 1512, 1532, 1603, 1642, 1676, 1704, 1727, 1758, 1908, 1953, 2015, 2057, 2165, 2181, 2265, 2448], '70,': [584, 887, 936], '131–': [585], '139.': [586], '(2007)': [600, 713, 741, 1544, 1811, 1968], 'Family-based': [601, 1660], 'analysis': [603, 821, 1528, 1638], 'ordered': [605], 'categorical': [606], 'phenotypes,': [607], 'covariates': [608], 'interactions.': [610, 722, 1309, 1672], 'Epidemiol': [612, 699, 844, 906, 1018, 1091, 1513, 1533, 1604, 1643, 1759, 2016, 2166, 2182, 2449], '31,': [613], '1–': [614], '8.': [615], 'Breiman,': [616, 626, 636], 'L.': [617, 627, 1218, 1290, 1387, 1525, 1684, 1987, 2024, 2029, 2071, 2276], '(1996)': [618, 2149], 'predictors.': [620], 'Mach': [621, 631], '26,': [623, 845], '123–': [624], '140.': [625], '(2001)': [628, 1078, 1190, 1526, 2041, 2439], 'forests.': [630, 1702, 2262], '45,': [633], '5–': [634], '32.': [635, 1706], 'L.,': [637, 679, 941, 990, 1044, 1115, 1146, 1182, 1321, 1649, 1682, 1738, 2281, 2293, 2305], 'Friedman,': [638], 'Olshen,': [641], 'R.': [642, 739, 761, 788, 953, 1098, 1269, 1631, 1713, 1860, 1887, 2249, 2304, 2323], 'Stone,': [645], '(1984)': [648], 'Classification': [649], 'trees.': [652], 'Belmont': [653], ',': [654], 'CA': [655], ':': [656], 'Wadsworth.': [657], 'Buehlmann,': [658], 'Yu,': [661], 'B.': [662, 813, 913, 1056, 1107, 1221, 1764, 1810, 1868, 1913, 2065, 2437], '(2002)': [663, 855, 920], 'Analyzing': [664], 'bagging.': [665], 'Statist': [667], '30,': [668, 1760], '927–': [669], '961.': [670], 'Bureau,': [671], 'A.,': [672, 1027, 1037, 1329, 1372, 1376, 1568, 1574, 1612, 1765, 1863, 2298, 2391], 'Dupuis,': [673], 'Falls,': [675], 'K.,': [676, 914, 1121, 1432, 1571, 1792, 1855, 1869, 2396], 'Lunetta,': [677, 1647, 1680], 'Hayward,': [680, 1683], 'B.,': [681, 1039, 1113, 1424, 1441, 1685, 2394], 'Keith,': [682], 'Eerdewegh,': [686, 1690], 'V.': [688, 1101, 1570, 2384, 2411], '(2005)': [689, 793, 1057, 1503, 1715], 'Identifying': [690, 1504], 'predictive': [692], 'phenotype': [694], 'using': [695, 745, 871, 1239, 1507, 1529, 1700, 1938, 1976, 2083, 2160, 2213], 'Forests.': [697], '28,': [700, 1514], '171–': [701], '182.': [702], 'Chen,': [703], 'X.,': [704, 2307], 'Liu,': [705, 1795], 'Zhang,': [708, 711, 1152], 'forest-based': [715], 'identifying': [718, 1934], 'gene': [719, 870, 1463, 1814, 1816], 'gene–gene': [721, 836, 1306, 1751, 1781, 2001, 2091], 'Proc': [723], 'Natl': [724, 1070], 'Acad': [725], 'Sci': [726, 2428], '104,': [728], '19199–': [729], '19203.': [730], 'Clark,': [731, 753, 781], 'G.,': [733, 755, 783, 1140, 1144, 1861, 1919, 2400], 'De': [734, 756, 784], 'Iorio,': [735, 757, 785], 'Griffiths,': [738, 760, 787], 'Bayesian': [742], 'logistic': [743], 'perfect': [747], 'phylogeny.': [748], 'Biostatistics': [749, 2216], '8,': [750], '32–': [751], '52.': [752], 'An': [764, 2133], 'evolutionary': [765], 'algorithm': [766, 802], 'find': [768], 'associations': [769, 795, 2154], 'dense': [771, 797], 'genetic': [772, 798, 801, 823, 1193, 1396, 1977, 2013, 2084, 2156], 'maps.': [773], 'IEEE': [774], 'Trans': [775], 'Evol': [776], 'Comp': [777], '12,': [778, 2116], '297–': [779], '306.': [780], 'M.,': [786, 950, 1105, 1135, 1263, 1317, 1325, 1382, 1421, 1434, 1446, 1768], 'Farrall,': [791], 'Finding': [794], 'maps:': [799], 'approach.': [803], '60,': [806], '97–': [807], '108.': [808], 'Cordell,': [809, 848], 'Barratt,': [812], 'Clayton,': [816, 852], '(2004)': [819, 897, 998, 1154, 1487, 1692, 2126, 2251, 2358], 'Case/pseudocontrol': [820], 'studies:': [825], 'unified': [827, 857], 'framework': [828, 961], 'detection': [830, 1008, 1016, 2087, 2419], 'genotype': [832], 'haplotype': [834], 'associations,': [835], 'gene-environment': [838], 'interactions,': [839], 'parent-of-origin': [841], 'effects.': [842], '167–': [846], '185.': [847], 'stepwise': [858], 'evaluating': [862], 'relative': [864], 'effects': [865, 1752], 'within': [868], 'case/control': [872], 'or': [873, 1552], 'family': [874], 'data:': [875, 1697, 2132], 'Application': [876], 'HLA': [878], 'type': [880], 'diabetes.': [882, 1950], 'Am': [883, 932, 1207, 1673, 2054], 'J': [884, 933, 1069, 1208, 1244, 1362, 1674, 2055, 2112, 2140], '124–': [888], '141.': [889], 'Culverhouse,': [890, 910], 'Klein,': [892], 'Shannon,': [895, 2303], 'W.': [896, 1988, 2032, 2072], 'Detecting': [898, 1969], 'contributing': [901], 'quantitative': [903], 'traits.': [904, 1641], '27,': [907], '141–': [908], '152.': [909], 'Suarez,': [912], 'Lin,': [915], 'Reich,': [918], 'perspective': [922], 'on': [923, 2375], 'epistasis:': [924], 'Limits': [925], 'displaying': [928], 'no': [929, 1553], 'main': [930], 'effect.': [931, 1555], '461–': [937], '471.': [938], 'Edwards,': [939], 'Turner,': [942], 'S.': [943, 949, 1029, 1077, 1184, 1226, 1262, 1651, 1740, 1791, 2315, 2318, 2322, 2387, 2434], 'D.,': [944, 1109, 1336, 1437, 1565, 1576, 1581, 1736, 1794, 1875, 1916, 1985, 2022, 2033, 2063], 'Torstenson,': [945], 'E.': [946, 952, 1380, 1390, 1587, 1732], 'Dudek,': [948], 'Martin,': [951, 1731], 'Ritchie,': [955, 1292, 1734, 1769, 1983, 2020, 2061], '(2010)': [958, 1274, 1888, 2227], 'general': [960], 'formal': [963], 'tests': [964, 1014, 1661, 2152], 'interaction': [966, 1241], 'after': [967], 'exhaustive': [968], 'search': [969], 'applications': [972], 'MDR': [974], 'MDR-PDT.': [976, 1757], 'PLoS': [977], 'One': [978], '5,': [979, 1166, 1787, 2381], 'e9363.': [980], 'Etzioni,': [981], 'Falcon,': [983], 'Gann,': [985], 'Kooperberg,': [988, 1498, 1517, 2104, 2121], 'Penson,': [991], 'F.': [993, 1543, 2035, 2036, 2393], 'Stampfer,': [995], 'Prostate-specific': [999], 'antigen': [1000, 1004], 'free': [1002], 'prostate-specific': [1003], 'early': [1007], 'prostate': [1010], 'cancer:': [1011, 1460], 'Do': [1012], 'combination': [1013], 'Cancer': [1017, 1071, 1090, 1245, 1471, 2338], 'Biomarkers': [1019, 1092], 'Prev': [1020, 1093], '13,': [1021, 2167], '1640–': [1022], '1645.': [1023], 'Feng,': [1024, 1797], 'Q.,': [1025, 1562, 1609], 'Balasubramanian,': [1026], 'Hawes,': [1028], 'Toure,': [1031], 'P.,': [1032, 1176, 1180, 1880], 'Sow,': [1033], 'Dem,': [1036], 'Dembele,': [1038], 'Critchlow,': [1040], 'W.,': [1042, 1049, 1125, 1291, 2025, 2274, 2287], 'Xi,': [1043], 'Lu,': [1045], 'McIntosh,': [1047], 'Young,': [1050], 'Kiviat,': [1054], 'N.': [1055, 1657], 'Detection': [1058, 1592, 1620, 1812], 'hypermethylated': [1060], 'genes': [1061, 1081, 1549, 2049], 'women': [1063], 'without': [1066], 'cervical': [1067], 'neoplasia.': [1068], 'Inst': [1072], '97,': [1073], '273–': [1074], '282.': [1075], 'Garte,': [1076], 'Metabolic': [1079], 'susceptibility': [1080, 1548], 'risk': [1084, 1238, 1899], 'factors:': [1085], 'Time': [1086], 'reassessment': [1089], '10,': [1094, 1705], '1233–': [1095], '1237.': [1096], 'Gentleman,': [1097], 'Carey,': [1100], 'Bates,': [1103], 'Bolstad,': [1106], 'Dudoit,': [1110], 'Ellis,': [1112], 'Gautier,': [1114], 'Ge,': [1116], 'Y.,': [1117, 1584, 2271, 2279, 2300, 2302, 2344, 2348, 2350], 'Gentry,': [1118], 'Hornik,': [1120], 'Hothorn,': [1122, 2189], 'Huber,': [1124], 'Iacus,': [1126], 'Irizarry,': [1128], 'Leisch,': [1130], 'Li,': [1132, 1561, 1608], 'Maechler,': [1134], 'Rossini,': [1136], 'Sawitzki,': [1139], 'Smith,': [1141], 'Smyth,': [1143], 'Tierney,': [1145], 'Yang,': [1147], 'Y.': [1149, 1335, 1436, 1882, 1883, 2286, 2319], 'Bioconductor:': [1155], 'Open': [1156], 'software': [1157, 1303], 'development': [1158], 'computational': [1160], 'biology': [1161], 'bioinformatics.': [1163], 'Genome': [1164], 'Biol': [1165, 2267], 'R80.': [1167], 'Geschwind,': [1168], 'Sowinski,': [1171], 'Lord,': [1173], 'Iversen,': [1175], 'Shestack,': [1177], 'Jones,': [1179], 'Ducat,': [1181], 'Spence,': [1183], 'AGRE': [1187], 'Steering': [1188], 'Committee': [1189], 'The': [1191, 1393, 1756], 'autism': [1192, 1202], 'resource': [1194, 1197], 'exchange:': [1195], 'related': [1204], 'neuropsychiatric': [1205], 'conditions.': [1206], '69,': [1211, 2058], '463–': [1212], '466.': [1213], 'Goodman,': [1214], 'Mechanic,': [1217], 'Luke,': [1220], 'Ambs,': [1223], 'Chanock,': [1225], 'Harris,': [1228], 'Exploring': [1232, 2127], 'SNP-SNP': [1233], 'colon': [1236], 'polymorphism': [1240], 'analysis.': [1242], 'Int': [1243], '118,': [1246], '1790–': [1247], '1797.': [1248], 'Greene,': [1249], 'Himmelstein,': [1252], 'Williams,': [1261], 'Enabling': [1275], 'personal': [1276], 'genomics': [1277], 'explicit': [1280], 'test': [1281], 'epistasis.': [1283], 'Pac': [1284], 'Symp': [1285], 'Biocomput,': [1286], '327–': [1287], '336.': [1288], 'Hahn,': [1289, 1737, 1986, 2023, 2070], '(2003)': [1299, 1927, 1993, 2109], 'Multifactor': [1300], 'dimensionality': [1301, 1997], 'reduction': [1302, 1998, 2043], 'detecting': [1305, 1547, 1719, 1780, 2000], 'gene–environment': [1308], 'Bioinformatics': [1310, 1494, 1849, 1979, 2099, 2380], '19,': [1311], '376–': [1312], '382.': [1313], 'Harth,': [1314, 1442], 'V.,': [1315, 1443, 1652, 1914], 'Schaefer,': [1316], 'Abel,': [1318], 'Maintz,': [1320], 'Neuhaus,': [1322], 'Besuden,': [1324], 'Primke,': [1326], 'Wilkesmann,': [1328], 'Thier,': [1330], 'Vetter,': [1332], 'Ko,': [1334, 1435], 'Bruening,': [1337], 'Bolt,': [1339, 1444], 'Ickstadt,': [1343, 1431, 1963, 2206, 2225], 'Head': [1346], 'neck': [1348], 'squamous-cell': [1349], 'its': [1352], 'polymorphic': [1355], 'enzymes': [1356], 'xenobiotic': [1358], 'metabolism': [1359], 'repair.': [1361], 'Toxicol': [1363], 'Environ': [1364], 'Health': [1365], '71,': [1367], '887–': [1368], '897.': [1369], 'Heidema,': [1370], 'Boer,': [1373], 'Nagelkerke,': [1377], 'N.,': [1378, 1796, 1803, 2027], 'Mariman,': [1379], 'van': [1383, 1479, 1689], 'de': [1384], 'A,': [1385], 'Feskens,': [1389], 'J.M.': [1391], 'challenge': [1394], 'epidemiologists:': [1397], 'How': [1398], 'analyze': [1400], 'large': [1401], 'numbers': [1402], 'relation': [1406], 'complex': [1408, 1640, 1724], 'diseases.': [1409, 1725, 2097], 'BMC': [1410, 1703, 2098, 2199, 2379], '7,': [1412], '23.': [1413], 'Justenhoven,': [1414], 'Hamann,': [1416], 'U.,': [1417], 'Schubert,': [1418], 'Zapatka,': [1420], 'Pierl,': [1422], 'Rabstein,': [1425], 'Selinski,': [1427], 'Mueller,': [1429], 'Gilbert,': [1433], 'Baisch,': [1438], 'Pesch,': [1440], 'Vollmert,': [1447], 'Illig,': [1449], 'Eils,': [1451], 'Dippon,': [1453], 'Brauch,': [1456], 'Breast': [1459, 1470], 'candidate': [1462], 'across': [1465], 'estrogen': [1467], 'metabolic': [1468], 'pathway.': [1469], 'Res': [1472, 2339], 'Treat': [1473], '108,': [1474], '137–': [1475], '149.': [1476], 'Keles,': [1477], 'der': [1480], 'Laan,': [1481], 'Vulpe,': [1485], 'Regulatory': [1488], 'motif': [1489], 'finding': [1490], 'regression.': [1493, 1511, 1531, 2111, 2215], '20,': [1495], '2799–': [1496], '2811.': [1497], 'I.': [1502, 1590, 1618, 1967, 2223], 'interacting': [1505], 'Monte': [1508], 'Carlo': [1509], '157–': [1515], '170.': [1516], 'I.,': [1520, 1873, 2103, 2120], 'LeBlanc,': [1521, 2107, 2124], 'Hsu,': [1524], 'Sequence': [1527], '21,': [1534, 2450], '626–': [1535], '631.': [1536], 'Kotti,': [1537], 'Bickeboeller,': [1539], 'Clerget-Darpoux,': [1542], 'Strategy': [1545], 'weak': [1551], 'marginal': [1554], '63,': [1558, 1828], '85–': [1559], '92.': [1560], 'Louis,': [1566, 1610], 'Lasseter,': [1569], 'McGrath,': [1572], 'Avramopoulos,': [1575], 'Wolyniec,': [1577], 'Valle,': [1580], 'Liang,': [1582], 'Pulver,': [1585], '(2010a)': [1591], 'SNP–SNP': [1594, 1622], 'parents': [1599], 'schizophrenic': [1601], '34,': [1605], '396–': [1606], '406.': [1607], '(2010b)': [1619], '(in': [1627], 'revision).': [1628], 'Lucek,': [1629], 'Ott,': [1633], '(1997)': [1635], 'Neural': [1636], 'network': [1637, 1931, 2081, 2361], '14,': [1644, 2340], '1101–': [1645], '1106.': [1646], 'Faraone,': [1650], 'Biederman,': [1653], 'Laird,': [1656], '(2000)': [1659], 'use': [1667], 'unaffected': [1668], 'sibs,': [1669], 'covariates,': [1670], '66,': [1677], '605–': [1678], '614.': [1679], 'Segal,': [1686, 2241], 'Screening': [1693], 'large-scale': [1694], 'Exploiting': [1698], 'random': [1701], 'Marchini,': [1707], 'Donnely,': [1709], 'Cardon,': [1712], 'Genome-wide': [1716], 'strategies': [1717], 'multiple': [1720], 'loci': [1721], 'influence': [1723], 'Nat': [1726], '37,': [1728], '413–': [1729], '416.': [1730], 'Kang,': [1739], 'method': [1748], 'identify': [1750], 'nuclear': [1754], 'families:': [1755], '111–': [1761], '123.': [1762], 'McKinney,': [1763], 'Reif,': [1766], 'Machine': [1777], 'learning': [1778, 1843], 'interactions:': [1782], 'review.': [1784], 'Appl': [1785, 2264], 'Bioinform': [1786, 2200], '77–': [1788], '88.': [1789], 'Musani,': [1790], 'Shriner,': [1793], 'Coffey,': [1799], 'Yi,': [1802], 'Tiwari,': [1804], 'Allison,': [1808], '×': [1815], 'genome-wide': [1819], 'human': [1823, 2096], 'population': [1824, 2446], 'data.': [1825], '67–': [1829], '84.': [1830], 'Nicodemus,': [1831, 1853], 'Malley,': [1835], '(2009)': [1838], 'Predictor': [1839], 'correlation': [1840], 'impacts': [1841], 'machine': [1842], 'algorithms:': [1844], 'Implications': [1845], 'genomic': [1847, 2131], 'studies.': [1848, 2238], '25,': [1850], '1884–': [1851], '1890.': [1852], 'Callicott,': [1856], 'Higier,': [1859], 'Luna,': [1862], 'Nixon,': [1864], 'Lipska,': [1867], 'Vakkalanka,': [1870], 'Giegling,': [1872], 'Rujescu,': [1874], 'Clair,': [1876], 'Muglia,': [1879], 'Shugart,': [1881], 'Weinberger,': [1885], 'Evidence': [1889], 'statistical': [1891], 'epistasis': [1892], 'disc1,': [1894], 'cit': [1895], 'ndel1': [1897], 'impacting': [1898], 'schizophrenia:': [1901], 'Biological': [1902], 'validation': [1903], 'functional': [1905], 'neuroimaging.': [1906], '127,': [1909], '441–': [1910], '452.': [1911], 'North,': [1912], 'Curtis,': [1915], 'Cassell,': [1917], 'Hitman,': [1920], 'Sham,': [1924], 'Assessing': [1928], 'optimal': [1929], 'neural': [1930, 2080, 2360], 'architecture': [1932, 2082], 'disease-associated': [1935], 'multi-marker': [1936], 'genotypes': [1937], 'permutation': [1940], 'test,': [1941], 'application': [1943], 'calpain': [1945], '10': [1946], 'associated': [1948], '67,': [1954], '348–': [1955], '356.': [1956], 'Nunkesser,': [1957], 'Bernholt,': [1959], 'Wegener,': [1966], 'high-order': [1970, 2045], 'programming.': [1978], '23,': [1980], '3280–': [1981], '3288.': [1982], 'Power': [1994], 'multifactor': [1996], 'presence': [2005], 'genotyping': [2007], 'error,': [2008], 'missing': [2009], 'phenocopy,': [2011], 'heterogeneity.': [2014], '24,': [2017], '150–': [2018], '157.': [2019], 'Roodi,': [2026], 'Bailey,': [2028], 'Dupont,': [2031], 'Parl,': [2034], 'Multifactor-dimensionality': [2042], 'reveals': [2044], 'among': [2047], 'estrogen-metabolism': [2048], 'sporadic': [2051], 'breast': [2052], 'cancer.': [2053], '138–': [2059], '147.': [2060], 'White,': [2064], 'Parker,': [2067], '(2003b)': [2077], 'Optimization': [2078], 'programming': [2085], 'improves': [2086], 'modeling': [2089], '4,': [2100], '28.': [2101], 'Logic': [2110], 'Comput': [2113], 'Graph': [2114], 'Stat': [2115, 2263], '475–': [2117], '511.': [2118], 'high-dimensional': [2130], 'overview': [2134], 'regression,': [2137], 'applications.': [2139], 'Mult': [2141], 'Anal': [2142], '90,': [2143], '178–': [2144], '195.': [2145], 'Schaid,': [2146, 2170], 'General': [2150], 'score': [2151], 'markers': [2157], 'cases': [2161], 'their': [2163], 'parents.': [2164], '423–': [2168], '449.': [2169], '(1999)': [2173], 'Likelihoods': [2174], 'TDT': [2176], 'case-parents': [2179], 'design.': [2180], '16,': [2183], '250–': [2184], '260.': [2185], 'Schmid,': [2186], 'Flexible': [2192], 'boosting': [2193], 'accelerated': [2195], 'failure': [2196], 'time': [2197], 'models.': [2198], '9,': [2201, 2217], '269.': [2202], 'Identification': [2209], 'SNP': [2211], '187–': [2218], '198.': [2219], 'Testing': [2228], 'sets': [2231], 'doi:10.1093/biostatistics/kxq042.': [2240], 'Barbour,': [2244], 'Grant,': [2248], 'Relating': [2252], 'HIV-1': [2253], 'sequence': [2254, 2443], 'variation': [2255], 'replication': [2257], 'capacity': [2258], 'via': [2259], 'Mol': [2266], '3,': [2268, 2429], '2.': [2269], 'Suehiro,': [2270], 'Wong,': [2272], 'Chirieac,': [2275], 'Kondo,': [2278], 'Shen,': [2280], 'Webb,': [2282], 'Chan,': [2285, 2288, 2291], 'S.Y.,': [2290], 'Wu,': [2294], 'Rashid,': [2297], 'Hamanaka,': [2299], 'Hinoda,': [2301], 'Wang,': [2306], 'Morris,': [2308], 'Issa,': [2310], 'Yuen,': [2314], 'Leung,': [2317], 'Hamilton,': [2321], 'Epigenetic-genetic': [2325], 'apc/wnt,': [2329], 'ras/raf,': [2330], 'p53': [2332], 'pathways': [2333], 'colorectal': [2335], 'carcinoma.': [2336], 'Clin': [2337, 2426], '2560–': [2341], '2569.': [2342], 'Tomita,': [2343], 'Tomida,': [2345], 'Hasegawa,': [2347], 'Suzuki,': [2349], 'Shirakawa,': [2351], 'Kobayashi,': [2353], 'Honda,': [2356], 'Artificial': [2359], 'selection': [2364], 'susceptible': [2366], 'construction': [2371], 'prediction': [2373], 'model': [2374], 'childhood': [2376], 'allergic': [2377], 'asthma.': [2378], '120.': [2382], 'Vaidya,': [2383], 'Waikar,': [2386], 'Ferguson,': [2389], 'Collings,': [2392], 'Sunderland,': [2395], 'Gioules,': [2397], 'Bradwin,': [2399], 'Matsouaka,': [2401], 'Betensky,': [2403], 'Curhan,': [2405], 'Bonventre,': [2409], 'Urinary': [2413], 'biomarkers': [2414], 'sensitive': [2416], 'specific': [2418], 'acute': [2421], 'kidney': [2422], 'injury': [2423], 'humans.': [2425], 'Transl': [2427], '200–': [2430], '208.': [2431], 'Witte,': [2432], 'Fijal,': [2436], 'Introduction:': [2440], 'Analysis': [2441], 'structure.': [2447], '600–': [2451], '601.': [2452], 'Citing': [2453], 'Literature': [2454], 'Volume75,': [2455], 'Issue1January': [2456], '2011Pages': [2457], 'ReferencesRelatedInformation': [2459]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1516948452', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-09T08:43:26.329791', 'created_date': '2016-06-24'}