Publication Information

{'id': 'https://openalex.org/W150469492', 'doi': None, 'title': 'Efficacy of olanzapine: an overview of pivotal clinical trials.', 'display_name': 'Efficacy of olanzapine: an overview of pivotal clinical trials.', 'publication_year': 1997, 'publication_date': '1997-01-01', 'ids': {'openalex': 'https://openalex.org/W150469492', 'mag': '150469492', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9265910'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9265910', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5016744088', 'display_name': 'Charles M. Beasley', 'orcid': 'https://orcid.org/0000-0001-8743-7691'}, 'institutions': [{'id': 'https://openalex.org/I168537998', 'display_name': 'Eli Lilly (United States)', 'ror': 'https://ror.org/01qat3289', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I168537998']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C M Beasley', 'raw_affiliation_strings': ['Psychopharmacology Division, Eli Lilly and Company, Indianapolis, IN 46285, USA.'], 'affiliations': [{'raw_affiliation_string': 'Psychopharmacology Division, Eli Lilly and Company, Indianapolis, IN 46285, USA.', 'institution_ids': ['https://openalex.org/I168537998']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109214489', 'display_name': 'Gary D. Tollefson', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'G D Tollefson', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5112989577', 'display_name': 'P.V. Tran', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'P V Tran', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 8.494, 'has_fulltext': False, 'cited_by_count': 102, 'citation_normalized_percentile': {'value': 0.885306, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '58 Suppl 10', 'issue': None, 'first_page': '7', 'last_page': '12'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10023', 'display_name': 'Schizophrenia research and treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10023', 'display_name': 'Schizophrenia research and treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11071', 'display_name': 'Treatment of Major Depression', 'score': 0.9945, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10854', 'display_name': 'Bipolar Disorder and Treatment', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dopamine-antagonist', 'display_name': 'Dopamine antagonist', 'score': 0.70449793}, {'id': 'https://openalex.org/keywords/antipsychotic-agent', 'display_name': 'Antipsychotic Agent', 'score': 0.49479622}, {'id': 'https://openalex.org/keywords/typical-antipsychotic', 'display_name': 'Typical antipsychotic', 'score': 0.41211697}], 'concepts': [{'id': 'https://openalex.org/C2776619155', 'wikidata': 'https://www.wikidata.org/wiki/Q201872', 'display_name': 'Olanzapine', 'level': 3, 'score': 0.9804187}, {'id': 'https://openalex.org/C2780948584', 'wikidata': 'https://www.wikidata.org/wiki/Q251347', 'display_name': 'Haloperidol', 'level': 3, 'score': 0.9197185}, {'id': 'https://openalex.org/C2780864610', 'wikidata': 'https://www.wikidata.org/wiki/Q221361', 'display_name': 'Clozapine', 'level': 3, 'score': 0.8712983}, {'id': 'https://openalex.org/C2781353949', 'wikidata': 'https://www.wikidata.org/wiki/Q3271533', 'display_name': 'Dopamine antagonist', 'level': 4, 'score': 0.70449793}, {'id': 'https://openalex.org/C2776921671', 'wikidata': 'https://www.wikidata.org/wiki/Q758295', 'display_name': 'Atypical antipsychotic', 'level': 4, 'score': 0.603282}, {'id': 'https://openalex.org/C2776412080', 'wikidata': 'https://www.wikidata.org/wiki/Q7431605', 'display_name': 'Schizophrenia (object-oriented programming)', 'level': 2, 'score': 0.5566698}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.54056555}, {'id': 'https://openalex.org/C2780494398', 'wikidata': 'https://www.wikidata.org/wiki/Q208144', 'display_name': 'Antipsychotic', 'level': 3, 'score': 0.535733}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.5122139}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.5100251}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.5016761}, {'id': 'https://openalex.org/C2910202354', 'wikidata': 'https://www.wikidata.org/wiki/Q208144', 'display_name': 'Antipsychotic Agent', 'level': 4, 'score': 0.49479622}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.44246382}, {'id': 'https://openalex.org/C2775870346', 'wikidata': 'https://www.wikidata.org/wiki/Q2554162', 'display_name': 'Typical antipsychotic', 'level': 5, 'score': 0.41211697}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.36097378}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.3265998}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29507697}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.20912641}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D010890', 'descriptor_name': 'Pirenzepine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D012559', 'descriptor_name': 'Schizophrenia', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000208', 'descriptor_name': 'Acute Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001569', 'descriptor_name': 'Benzodiazepines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006220', 'descriptor_name': 'Haloperidol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006220', 'descriptor_name': 'Haloperidol', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015337', 'descriptor_name': 'Multicenter Studies as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077152', 'descriptor_name': 'Olanzapine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010890', 'descriptor_name': 'Pirenzepine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D010890', 'descriptor_name': 'Pirenzepine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010919', 'descriptor_name': 'Placebos', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011569', 'descriptor_name': 'Psychiatric Status Rating Scales', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016032', 'descriptor_name': 'Randomized Controlled Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012559', 'descriptor_name': 'Schizophrenia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012565', 'descriptor_name': 'Schizophrenic Psychology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9265910', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.79, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 3, 'referenced_works': ['https://openalex.org/W122505910', 'https://openalex.org/W1787454655', 'https://openalex.org/W2032336977'], 'related_works': ['https://openalex.org/W2169055778', 'https://openalex.org/W2146091186', 'https://openalex.org/W2084253035', 'https://openalex.org/W2053754882', 'https://openalex.org/W2000689909', 'https://openalex.org/W1999327683', 'https://openalex.org/W1990396073', 'https://openalex.org/W1973464250', 'https://openalex.org/W1966237751', 'https://openalex.org/W150469492'], 'abstract_inverted_index': {'Olanzapine': [0], 'is': [1, 54], 'a': [2, 33], 'new': [3], '"atypical"': [4], 'antipsychotic': [5], 'agent': [6, 31], 'that': [7, 52], 'belongs': [8], 'chemically': [9], 'to': [10, 22, 28, 43], 'the': [11, 29, 68, 71], 'thienobenzodiazepine': [12], 'class.': [13], 'Its': [14], 'relatively': [15], 'greater': [16], 'binding': [17], 'affinity': [18], 'for': [19, 59, 67], '5-HT2': [20], 'compared': [21], 'D2': [23], 'receptors': [24], 'makes': [25], 'it': [26], 'similar': [27], 'atypical': [30], 'clozapine,': [32], 'serotonin/dopamine': [34], 'antagonist.': [35], 'Four': [36], 'double-blind': [37], 'pivotal': [38], 'studies,': [39], 'which': [40], 'compare': [41], 'olanzapine': [42, 53], 'placebo': [44], 'and/or': [45], 'haloperidol,': [46], 'are': [47], 'presented.': [48], 'The': [49], 'results': [50], 'suggest': [51], 'as': [55, 57], 'effective': [56, 64], 'haloperidol': [58, 66], 'positive': [60], 'symptoms': [61, 73], 'and': [62], 'more': [63], 'than': [65], 'treatment': [69], 'of': [70, 74], 'negative': [72], 'schizophrenia.': [75]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W150469492', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-14T17:44:03.008415', 'created_date': '2016-06-24'}