Publication Information

{'id': 'https://openalex.org/W1499729288', 'doi': 'https://doi.org/10.1158/1538-7445.am2014-942', 'title': 'Abstract 942: Imputation from The 1000 Genomes Project identifies rare large effect variants of BRCA2-K3326X and CHEK2-I157T as risk factors for lung cancer; a study from the TRICL consortium', 'display_name': 'Abstract 942: Imputation from The 1000 Genomes Project identifies rare large effect variants of BRCA2-K3326X and CHEK2-I157T as risk factors for lung cancer; a study from the TRICL consortium', 'publication_year': 2014, 'publication_date': '2014-10-01', 'ids': {'openalex': 'https://openalex.org/W1499729288', 'doi': 'https://doi.org/10.1158/1538-7445.am2014-942', 'mag': '1499729288'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2014-942', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5107915484', 'display_name': 'Maria Teresa Landi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Maria Teresa Landi', 'raw_affiliation_strings': ['1NCI-DCEG, Bethesda, MD;'], 'affiliations': [{'raw_affiliation_string': '1NCI-DCEG, Bethesda, MD;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100374823', 'display_name': 'Yufei Wang', 'orcid': 'https://orcid.org/0000-0002-2573-0611'}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Yufei Wang', 'raw_affiliation_strings': ['2Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom;'], 'affiliations': [{'raw_affiliation_string': '2Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom;', 'institution_ids': ['https://openalex.org/I142947616']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089473534', 'display_name': 'James McKay', 'orcid': 'https://orcid.org/0000-0002-1787-3874'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'James D. Mckay', 'raw_affiliation_strings': ['3International Agency for Research on Cancer, Lyon, France.'], 'affiliations': [{'raw_affiliation_string': '3International Agency for Research on Cancer, Lyon, France.', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063931663', 'display_name': 'Þórunn Rafnar', 'orcid': 'https://orcid.org/0000-0003-0491-7046'}, 'institutions': [{'id': 'https://openalex.org/I1327191685', 'display_name': 'deCODE Genetics (Iceland)', 'ror': 'https://ror.org/04dzdm737', 'country_code': 'IS', 'type': 'company', 'lineage': ['https://openalex.org/I1327191685']}], 'countries': ['IS'], 'is_corresponding': False, 'raw_author_name': 'Thorunn Rafnar', 'raw_affiliation_strings': ['4deCODE Genetics/Amgen, Reykjavik, Iceland;'], 'affiliations': [{'raw_affiliation_string': '4deCODE Genetics/Amgen, Reykjavik, Iceland;', 'institution_ids': ['https://openalex.org/I1327191685']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100773143', 'display_name': 'Zhaoming Wang', 'orcid': 'https://orcid.org/0000-0001-7556-3869'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Zhaoming Wang', 'raw_affiliation_strings': ['1NCI-DCEG, Bethesda, MD;'], 'affiliations': [{'raw_affiliation_string': '1NCI-DCEG, Bethesda, MD;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089552905', 'display_name': 'Maria Timofeeva', 'orcid': 'https://orcid.org/0000-0002-2503-4253'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Maria Timofeeva', 'raw_affiliation_strings': ['3International Agency for Research on Cancer, Lyon, France.'], 'affiliations': [{'raw_affiliation_string': '3International Agency for Research on Cancer, Lyon, France.', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059774512', 'display_name': 'Peter Broderick', 'orcid': 'https://orcid.org/0000-0002-8348-5829'}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Peter Broderick', 'raw_affiliation_strings': ['2Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom;'], 'affiliations': [{'raw_affiliation_string': '2Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom;', 'institution_ids': ['https://openalex.org/I142947616']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009208804', 'display_name': 'Hreinn Stefánsson', 'orcid': 'https://orcid.org/0000-0002-9331-6666'}, 'institutions': [{'id': 'https://openalex.org/I1327191685', 'display_name': 'deCODE Genetics (Iceland)', 'ror': 'https://ror.org/04dzdm737', 'country_code': 'IS', 'type': 'company', 'lineage': ['https://openalex.org/I1327191685']}], 'countries': ['IS'], 'is_corresponding': False, 'raw_author_name': 'Kari Stefansson', 'raw_affiliation_strings': ['4deCODE Genetics/Amgen, Reykjavik, Iceland;'], 'affiliations': [{'raw_affiliation_string': '4deCODE Genetics/Amgen, Reykjavik, Iceland;', 'institution_ids': ['https://openalex.org/I1327191685']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028712491', 'display_name': 'Angela Risch', 'orcid': 'https://orcid.org/0000-0002-8026-5505'}, 'institutions': [{'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}, {'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}, {'id': 'https://openalex.org/I87890613', 'display_name': 'Epigenomics (Germany)', 'ror': 'https://ror.org/0490dah44', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I87890613']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Angela Risch', 'raw_affiliation_strings': ['5Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany;'], 'affiliations': [{'raw_affiliation_string': '5Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany;', 'institution_ids': ['https://openalex.org/I17937529', 'https://openalex.org/I223822909', 'https://openalex.org/I87890613']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091653870', 'display_name': 'Stephen J. Chanock', 'orcid': 'https://orcid.org/0000-0002-2324-3393'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Stephen J. Chanock', 'raw_affiliation_strings': ['1NCI-DCEG, Bethesda, MD;'], 'affiliations': [{'raw_affiliation_string': '1NCI-DCEG, Bethesda, MD;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091331939', 'display_name': 'David C. Christiani', 'orcid': 'https://orcid.org/0000-0002-0301-0242'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David C. Christiani', 'raw_affiliation_strings': ['6Department of Environmental Health, Harvard School of Public Health, Boston, MA;'], 'affiliations': [{'raw_affiliation_string': '6Department of Environmental Health, Harvard School of Public Health, Boston, MA;', 'institution_ids': ['https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053712654', 'display_name': 'Rayjean J. Hung', 'orcid': 'https://orcid.org/0000-0002-4486-7496'}, 'institutions': [{'id': 'https://openalex.org/I210557978', 'display_name': 'Lunenfeld-Tanenbaum Research Institute', 'ror': 'https://ror.org/01s5axj25', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I1291836623', 'https://openalex.org/I210557978', 'https://openalex.org/I4210130843']}, {'id': 'https://openalex.org/I1291836623', 'display_name': 'Mount Sinai Hospital', 'ror': 'https://ror.org/05deks119', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1291836623', 'https://openalex.org/I4210130843']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Rayjean J. Hung', 'raw_affiliation_strings': ['7Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada;'], 'affiliations': [{'raw_affiliation_string': '7Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada;', 'institution_ids': ['https://openalex.org/I210557978', 'https://openalex.org/I1291836623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001258652', 'display_name': 'Paul Brennan', 'orcid': 'https://orcid.org/0000-0002-0518-8714'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Paul Brennan', 'raw_affiliation_strings': ['3International Agency for Research on Cancer, Lyon, France.'], 'affiliations': [{'raw_affiliation_string': '3International Agency for Research on Cancer, Lyon, France.', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022550644', 'display_name': 'Richard S. Houlston', 'orcid': 'https://orcid.org/0000-0002-5268-0242'}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Richard S. Houlston', 'raw_affiliation_strings': ['2Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom;'], 'affiliations': [{'raw_affiliation_string': '2Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom;', 'institution_ids': ['https://openalex.org/I142947616']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5028989565', 'display_name': 'Christopher I. Amos', 'orcid': 'https://orcid.org/0000-0002-8540-7023'}, 'institutions': [{'id': 'https://openalex.org/I107672454', 'display_name': 'Dartmouth College', 'ror': 'https://ror.org/049s0rh22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I107672454']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christopher I. Amos', 'raw_affiliation_strings': ['8Center for Genomic Medicine Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Dartmouth, NH.'], 'affiliations': [{'raw_affiliation_string': '8Center for Genomic Medicine Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Dartmouth, NH.', 'institution_ids': ['https://openalex.org/I107672454']}]}], 'institution_assertions': [], 'countries_distinct_count': 6, 'institutions_distinct_count': 10, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.984, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.656127, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '74', 'issue': '19_Supplement', 'first_page': '942', 'last_page': '942'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10769', 'display_name': 'BRCA gene mutations in cancer', 'score': 0.9658, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10769', 'display_name': 'BRCA gene mutations in cancer', 'score': 0.9658, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13984', 'display_name': 'Nutrition, Genetics, and Disease', 'score': 0.9516, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/1000-genomes-project', 'display_name': '1000 Genomes Project', 'score': 0.6177953}, {'id': 'https://openalex.org/keywords/imputation', 'display_name': 'Imputation (statistics)', 'score': 0.5563956}, {'id': 'https://openalex.org/keywords/genome-wide-association-study', 'display_name': 'Genome-wide Association Study', 'score': 0.54739577}], 'concepts': [{'id': 'https://openalex.org/C97425143', 'wikidata': 'https://www.wikidata.org/wiki/Q164786', 'display_name': '1000 Genomes Project', 'level': 5, 'score': 0.6177953}, {'id': 'https://openalex.org/C156957248', 'wikidata': 'https://www.wikidata.org/wiki/Q1862216', 'display_name': 'Odds ratio', 'level': 2, 'score': 0.6038278}, {'id': 'https://openalex.org/C58041806', 'wikidata': 'https://www.wikidata.org/wiki/Q1660484', 'display_name': 'Imputation (statistics)', 'level': 3, 'score': 0.5563956}, {'id': 'https://openalex.org/C106208931', 'wikidata': 'https://www.wikidata.org/wiki/Q1098876', 'display_name': 'Genome-wide association study', 'level': 5, 'score': 0.54739577}, {'id': 'https://openalex.org/C105795698', 'wikidata': 'https://www.wikidata.org/wiki/Q12483', 'display_name': 'Statistics', 'level': 1, 'score': 0.50242877}, {'id': 'https://openalex.org/C153209595', 'wikidata': 'https://www.wikidata.org/wiki/Q501128', 'display_name': 'Single-nucleotide polymorphism', 'level': 4, 'score': 0.48948896}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.44587943}, {'id': 'https://openalex.org/C151956035', 'wikidata': 'https://www.wikidata.org/wiki/Q1132755', 'display_name': 'Logistic regression', 'level': 2, 'score': 0.41984773}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.38466835}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.35373074}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.31507272}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.26779637}, {'id': 'https://openalex.org/C9357733', 'wikidata': 'https://www.wikidata.org/wiki/Q6878417', 'display_name': 'Missing data', 'level': 2, 'score': 0.26065445}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.22509143}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.15689197}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2014-942', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Partnerships for the goals', 'score': 0.52, 'id': 'https://metadata.un.org/sdg/17'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4387141664', 'https://openalex.org/W4381248205', 'https://openalex.org/W4317801964', 'https://openalex.org/W4286002085', 'https://openalex.org/W4283582241', 'https://openalex.org/W2178628622', 'https://openalex.org/W2126214064', 'https://openalex.org/W2122946544', 'https://openalex.org/W2095322240', 'https://openalex.org/W1968654496'], 'abstract_inverted_index': {'Abstract': [0], 'We': [1, 249, 275], 'conducted': [2, 40, 221], 'imputation': [3, 126, 344], 'to': [4, 165, 197, 228, 236, 245, 332], 'The': [5, 79, 123, 173, 401], '1000': [6, 80, 402], 'Genomes': [7, 81, 403], 'Project': [8, 82, 404], 'of': [9, 13, 18, 46, 99, 125, 143, 202, 240, 262, 270, 311, 410, 429, 434], 'genome-wide': [10, 252], 'association': [11, 100, 174, 279, 300], 'studies': [12, 45, 148], 'lung': [14, 105, 179, 256, 290, 333, 418], 'cancer': [15, 106, 180, 257, 334, 354], 'in': [16, 43, 114, 121, 140, 295], 'populations': [17], 'European': [19], 'ancestry,': [20], 'with': [21, 258], '11,348': [22], 'cases': [23, 48, 58], 'and': [24, 49, 52, 59, 104, 134, 152, 178, 207, 232, 269, 289, 304, 335, 412], '15,861': [25], 'controls': [26, 51, 61], 'from': [27, 33, 62, 78, 145, 158, 356, 400, 422], 'four': [28, 147], 'large': [29, 407], 'studies,': [30], 'including': [31], 'subjects': [32], '13': [34], 'countries.': [35, 64], 'As': [36], 'a': [37, 110, 141, 420], 'follow-up,': [38], 'we': [39], 'in-silico': [41], 'replication': [42], 'two': [44], '2,303': [47], '27,350': [50], 'directly': [53, 135], 'genotyped': [54], 'an': [55, 223, 278], 'additional': [56], '7,943': [57], '10,945': [60], '14': [63], 'Data': [65], 'were': [66, 107, 195, 213, 247], 'imputed': [67, 102, 133], 'for': [68, 71, 150, 160, 167, 199, 230, 254, 328, 417, 438], 'all': [69], 'scans': [70], 'over': [72], '10': [73], 'million': [74], 'SNPs': [75, 103, 137, 194], 'using': [76, 92, 192, 222, 316], 'data': [77], '(Phase': [83], '1': [84], 'integrated': [85], 'release': [86], '3,': [87], 'March': [88], '2012)': [89], 'as': [90, 127, 307, 414], 'reference,': [91], 'IMPUTE2,': [93], 'MaCH': [94], 'or': [95, 118], 'minimac': [96], 'software.': [97], 'Tests': [98], 'between': [101, 132, 175, 280, 301], 'performed': [108], 'under': [109], 'probabilistic': [111], 'dosage': [112], 'model': [113], 'SNPTEST,': [115], 'ProbABEL,': [116], 'MaCH2dat': [117], 'glm': [119], 'function': [120], 'R.': [122], 'fidelity': [124], 'assessed': [128, 183], 'by': [129, 184, 215, 309], 'the': [130, 146, 161, 168, 185, 200, 233, 238, 241, 259, 423, 430, 435], 'correlation': [131, 155], 'typed': [136], 'was': [138, 182, 220, 298], 'examined': [139], 'subset': [142], 'samples': [144], 'used': [149, 196], 'discovery': [151], 'showed': [153, 277], 'squared': [154], 'coefficients': [156], 'ranging': [157], '0.74': [159], 'rare': [162, 260, 347, 406], 'CHEK2': [163], 'variant': [164], '1.00': [166], 'more': [169], 'common': [170, 193, 281], 'TP63': [171], 'variant.': [172], 'each': [176], 'SNP': [177], 'risk': [181, 355, 415], 'Cochran-Armitage': [186], 'trend': [187], 'test.': [188], 'Principle': [189], 'components': [190], 'generated': [191], 'account': [198], 'possibility': [201], 'inflation.': [203], 'Odds': [204], 'ratios': [205], '(ORs)': [206], 'associated': [208], '95%': [209], 'confidence': [210], 'intervals': [211], '(CIs)': [212], 'calculated': [214], 'unconditional': [216], 'logistic': [217], 'regression.': [218], 'Meta-analysis': [219], 'inverse-variance': [224], 'approach.': [225], "Cochran's": [226], 'Q-statistic': [227], 'test': [229], 'heterogeneity': [231, 246], 'I2': [234], 'statistic': [235], 'quantify': [237], 'proportion': [239], 'total': [242], 'variation': [243, 282], 'due': [244], 'calculated.': [248], 'identified': [250], 'large-effect': [251], 'associations': [253], 'squamous': [255], 'variants': [261, 349, 409], 'BRCA2-K3326X': [263, 411], '(rs11571833;': [264], 'odds': [265], 'ratio': [266], '[OR]=2.47,': [267], 'P=4.74×10−20)': [268], 'CHEK2-I157T': [271, 413], '(rs17879961;': [272], 'OR=0.38': [273], 'P=1.27×10−13).': [274], 'also': [276], 'at': [283], '3q28': [284], '(TP63;': [285], 'rs13314271;': [286], 'OR=1.13,': [287], 'P=7.22×10−10)': [288], 'adenocarcinoma': [291], 'previously': [292], 'only': [293], 'reported': [294], 'Asians.': [296], 'There': [297], 'no': [299], 'these': [302], 'loci': [303], 'smoking': [305, 317], 'quantity': [306], 'measured': [308], 'number': [310], 'cigarettes': [312], 'smoked': [313], 'per': [314], 'day,': [315], 'information': [318], 'on': [319, 353], '43,693': [320], 'Icelandic': [321], 'subjects.': [322], 'These': [323], 'findings': [324], 'provide': [325], 'further': [326], 'evidence': [327], 'inherited': [329], 'genetic': [330], 'susceptibility': [331], 'its': [336], 'biological': [337], 'basis.': [338], 'Additionally,': [339], 'our': [340], 'analysis': [341], 'demonstrates': [342], 'that': [343], 'can': [345], 'identify': [346], 'disease-causing': [348], 'having': [350], 'substantive': [351], 'effects': [352], 'pre-existing': [357], 'GWAS': [358], 'data.': [359], 'Citation': [360], 'Format:': [361], 'Maria': [362, 374], 'Teresa': [363], 'Landi,': [364], 'Yufei': [365], 'Wang,': [366, 373], 'James': [367], 'D.': [368], 'Mckay,': [369], 'Thorunn': [370], 'Rafnar,': [371], 'Zhaoming': [372], 'Timofeeva,': [375], 'Peter': [376], 'Broderick,': [377], 'Kari': [378], 'Stefansson,': [379], 'Angela': [380], 'Risch,': [381], 'Stephen': [382], 'J.': [383, 389], 'Chanock,': [384], 'David': [385], 'C.': [386], 'Christiani,': [387], 'Rayjean': [388], 'Hung,': [390], 'Paul': [391], 'Brennan,': [392], 'Richard': [393], 'S.': [394], 'Houlston,': [395], 'Christopher': [396], 'I.': [397], 'Amos.': [398], 'Imputation': [399], 'identifies': [405], 'effect': [408], 'factors': [416], 'cancer;': [419], 'study': [421], 'TRICL': [424], 'consortium.': [425], '[abstract].': [426], 'In:': [427], 'Proceedings': [428], '105th': [431], 'Annual': [432], 'Meeting': [433], 'American': [436], 'Association': [437], 'Cancer': [439, 450], 'Research;': [440], '2014': [441], 'Apr': [442], '5-9;': [443], 'San': [444], 'Diego,': [445], 'CA.': [446], 'Philadelphia': [447], '(PA):': [448], 'AACR;': [449], 'Res': [451], '2014;74(19': [452], 'Suppl):Abstract': [453], 'nr': [454], '942.': [455], 'doi:10.1158/1538-7445.AM2014-942': [456]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1499729288', 'counts_by_year': [{'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2025-01-04T12:00:41.825118', 'created_date': '2016-06-24'}