Title: Mechanical and Structural Properties of Skeletal Bone in Wild‐Type and Mutant Zebrafish (Danio rerio)
Abstract:Chapter 22 Mechanical and Structural Properties of Skeletal Bone in Wild-Type and Mutant Zebrafish (Danio rerio) Fu-Zhai Cui, Fu-Zhai CuiSearch for more papers by this authorXiu-Mei Wang, Xiu-Mei Wang...Chapter 22 Mechanical and Structural Properties of Skeletal Bone in Wild-Type and Mutant Zebrafish (Danio rerio) Fu-Zhai Cui, Fu-Zhai CuiSearch for more papers by this authorXiu-Mei Wang, Xiu-Mei WangSearch for more papers by this author Fu-Zhai Cui, Fu-Zhai CuiSearch for more papers by this authorXiu-Mei Wang, Xiu-Mei WangSearch for more papers by this author Book Editor(s):Prof. Dr. Edmund Bäuerlein, Prof. Dr. Edmund Bäuerlein Max-Planck-Institute for Biochemistry, Department of Membrane Biochemistry, Am Klopferspitz 18 A, 82152 Planegg, GermanySearch for more papers by this author First published: 25 May 2007 https://doi.org/10.1002/9783527619443.ch22Citations: 1 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onFacebookTwitterLinked InRedditWechat Summary The zebrafish skeleton has a similar development process, biomineralization characteristics, and hierarchal levels of organization as human bone, though the Haversian system is absent. Based on its predominance in systematic mutagene-sis studies, it is clear that the zebrafish represents a potentially very powerful and simple model for studying bone mineralization and bone diseases at the molecular level. Notably, bone structural features observed by atomic force microscopy and transmission electron microscopy in the zebrafish system provide new visual evidence supporting the concept of surface mineralization on collagen fibrils, thereby creating the mineral-collagen complex. Comparative studies of the mechanical and structural properties of skeletal bone in wild-type and mutant zebrafish also contribute to our molecular-level understanding of biomineralization. Citing Literature Handbook of Biomineralization: Biological Aspects and Structure Formation RelatedInformationRead More
Publication Year: 2007
Publication Date: 2007-05-25
Language: en
Type: other
Indexed In: ['crossref']
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Cited By Count: 1
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