Title: ANTIMICROBIAL PEPTIDES:IMPORTANT ROLES IN HUMAN HEALTH AND DISEASES
Abstract:Antimicrobial peptides(AMPs)are one kind of polypeptides produced by living organisms' defense system. Substantial evidence accumulated in recent years indicates that AMPs not only possess direct anti...Antimicrobial peptides(AMPs)are one kind of polypeptides produced by living organisms' defense system. Substantial evidence accumulated in recent years indicates that AMPs not only possess direct antimicrobial activities but also have multiple immunomodulatory activities. They play an important role in both the innate and adaptive immunity of the host. Their expressions are closely related to many human diseases. Thus, antimicrobial peptides may have potential applications as new therapeutics agents. The intent of this article is to review the structures, expression and bioactivities of defensins and cathelicidin, the main families of AMPs in human. Correlations between human diseases and antimicrobial peptides are also discussed.Read More
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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