Publication Information

{'id': 'https://openalex.org/W1460282504', 'doi': None, 'title': 'The effect of diethylcarbamazine in a murine model of Brugia malayi microfilaraemia.', 'display_name': 'The effect of diethylcarbamazine in a murine model of Brugia malayi microfilaraemia.', 'publication_year': 1979, 'publication_date': '1979-01-01', 'ids': {'openalex': 'https://openalex.org/W1460282504', 'mag': '1460282504', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/312165', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2395783'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/312165', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113678587', 'display_name': 'Marguerite A. Neill', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I58956616', 'display_name': 'Case Western Reserve University', 'ror': 'https://ror.org/051fd9666', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I58956616']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Neill', 'raw_affiliation_strings': ['Case Western Reserve University ,'], 'affiliations': [{'raw_affiliation_string': 'Case Western Reserve University ,', 'institution_ids': ['https://openalex.org/I58956616']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5107502344', 'display_name': 'James W. Kazura', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'James Walter Kazura', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.596591, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 73, 'max': 75}, 'biblio': {'volume': '57', 'issue': '2', 'first_page': '329', 'last_page': '30'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13719', 'display_name': 'Phytochemistry and Bioactivity Studies', 'score': 0.9674, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13719', 'display_name': 'Phytochemistry and Bioactivity Studies', 'score': 0.9674, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11702', 'display_name': 'Parasitic Diseases Research and Treatment', 'score': 0.9638, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13385', 'display_name': 'Infectious Diseases and Mycology', 'score': 0.9331, 'subfield': {'id': 'https://openalex.org/subfields/3404', 'display_name': 'Small Animals'}, 'field': {'id': 'https://openalex.org/fields/34', 'display_name': 'Veterinary'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/diethylcarbamazine', 'display_name': 'Diethylcarbamazine', 'score': 0.99632907}, {'id': 'https://openalex.org/keywords/brugia-malayi', 'display_name': 'Brugia malayi', 'score': 0.9820734}, {'id': 'https://openalex.org/keywords/brugia-pahangi', 'display_name': 'Brugia pahangi', 'score': 0.4643657}, {'id': 'https://openalex.org/keywords/filarioidea', 'display_name': 'Filarioidea', 'score': 0.46258804}], 'concepts': [{'id': 'https://openalex.org/C2777411658', 'wikidata': 'https://www.wikidata.org/wiki/Q409267', 'display_name': 'Diethylcarbamazine', 'level': 4, 'score': 0.99632907}, {'id': 'https://openalex.org/C2775848585', 'wikidata': 'https://www.wikidata.org/wiki/Q139658', 'display_name': 'Brugia malayi', 'level': 4, 'score': 0.9820734}, {'id': 'https://openalex.org/C2777629521', 'wikidata': 'https://www.wikidata.org/wiki/Q815753', 'display_name': 'Filariasis', 'level': 3, 'score': 0.6186898}, {'id': 'https://openalex.org/C2779726973', 'wikidata': 'https://www.wikidata.org/wiki/Q578994', 'display_name': 'Helminthiasis', 'level': 2, 'score': 0.59915215}, {'id': 'https://openalex.org/C2776908094', 'wikidata': 'https://www.wikidata.org/wiki/Q572294', 'display_name': 'Anthelmintic', 'level': 2, 'score': 0.5789541}, {'id': 'https://openalex.org/C2776573122', 'wikidata': 'https://www.wikidata.org/wiki/Q4978677', 'display_name': 'Brugia pahangi', 'level': 3, 'score': 0.4643657}, {'id': 'https://openalex.org/C2780376107', 'wikidata': 'https://www.wikidata.org/wiki/Q1412499', 'display_name': 'Filarioidea', 'level': 4, 'score': 0.46258804}, {'id': 'https://openalex.org/C2778672586', 'wikidata': 'https://www.wikidata.org/wiki/Q311109', 'display_name': 'Wuchereria bancrofti', 'level': 4, 'score': 0.45286885}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.44213164}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4272455}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.41169122}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.40312964}, {'id': 'https://openalex.org/C165901193', 'wikidata': 'https://www.wikidata.org/wiki/Q3129936', 'display_name': 'Helminths', 'level': 2, 'score': 0.3452965}, {'id': 'https://openalex.org/C42972112', 'wikidata': 'https://www.wikidata.org/wiki/Q170201', 'display_name': 'Veterinary medicine', 'level': 1, 'score': 0.15634993}], 'mesh': [{'descriptor_ui': 'D004049', 'descriptor_name': 'Diethylcarbamazine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D005368', 'descriptor_name': 'Filariasis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D005370', 'descriptor_name': 'Filarioidea', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D008842', 'descriptor_name': 'Microfilariae', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000284', 'descriptor_name': 'Administration, Oral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004049', 'descriptor_name': 'Diethylcarbamazine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004049', 'descriptor_name': 'Diethylcarbamazine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D004353', 'descriptor_name': 'Drug Evaluation, Preclinical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005368', 'descriptor_name': 'Filariasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005370', 'descriptor_name': 'Filarioidea', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008842', 'descriptor_name': 'Microfilariae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/312165', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.77, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 3, 'referenced_works': ['https://openalex.org/W1971046537', 'https://openalex.org/W2193629683', 'https://openalex.org/W2331866097'], 'related_works': ['https://openalex.org/W2487276571', 'https://openalex.org/W2403675891', 'https://openalex.org/W2331866097', 'https://openalex.org/W2289328996', 'https://openalex.org/W2060095153', 'https://openalex.org/W2029953782', 'https://openalex.org/W1989064596', 'https://openalex.org/W1977860894', 'https://openalex.org/W157111005', 'https://openalex.org/W1460282504'], 'abstract_inverted_index': {'The': [0, 56], 'effect': [1], 'of': [2, 10, 16, 41, 59, 68, 71, 75, 84], 'diethylcarbamazine': [3, 42, 76], 'was': [4], 'tested': [5], 'in': [6, 33, 37], 'a': [7, 30, 46], 'murine': [8], 'model': [9, 58], 'Brugia': [11], 'malayi': [12, 61], 'microfilaraemia.': [13], 'A': [14], 'course': [15], 'therapy': [17], 'similar': [18], 'to': [19, 22, 27, 81], 'that': [20, 50], 'used': [21], 'treat': [23], 'human': [24], 'infection': [25], 'led': [26], 'more': [28], 'than': [29], '90%': [31], 'decrease': [32], 'circulating': [34], 'parasites.': [35], 'Experiments': [36], 'which': [38], 'different': [39], 'amounts': [40], 'were': [43], 'given': [44], 'as': [45], 'single': [47], 'dose': [48], 'indicated': [49], 'its': [51], 'microfilaricidal': [52, 86], 'activity': [53], 'is': [54], 'dose-dependent.': [55], 'animal': [57], 'B.': [60], 'microfilaraemia': [62], 'may': [63, 78], 'be': [64, 79], 'useful': [65], 'for': [66], 'studies': [67], 'the': [69, 82], 'mechanism': [70], 'action': [72], 'and': [73, 77], 'pharmacology': [74], 'applied': [80], 'screening': [83], 'new': [85], 'drugs.': [87]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1460282504', 'counts_by_year': [{'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-12-14T15:12:15.435163', 'created_date': '2016-06-24'}