Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W129591107', 'doi': 'https://doi.org/10.1016/b978-0-12-804182-6.00043-5', 'title': 'Genetic Hypercalciuria: A Major Risk Factor in Kidney Stones', 'display_name': 'Genetic Hypercalciuria: A Major Risk Factor in Kidney Stones', 'publication_year': 2018, 'publication_date': '2018-01-01', 'ids': {'openalex': 'https://openalex.org/W129591107', 'doi': 'https://doi.org/10.1016/b978-0-12-804182-6.00043-5', 'mag': '129591107'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/b978-0-12-804182-6.00043-5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463230', 'display_name': 'Elsevier eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'book-chapter', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5023488815', 'display_name': 'Orson W. Moe', 'orcid': 'https://orcid.org/0000-0001-9176-3414'}, 'institutions': [{'id': 'https://openalex.org/I867280407', 'display_name': 'The University of Texas Southwestern Medical Center', 'ror': 'https://ror.org/05byvp690', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I867280407']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Orson W. Moe', 'raw_affiliation_strings': ['University of Texas Southwestern Medical Center, Dallas, TX, United States.'], 'affiliations': [{'raw_affiliation_string': 'University of Texas Southwestern Medical Center, Dallas, TX, United States.', 'institution_ids': ['https://openalex.org/I867280407']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091483213', 'display_name': 'David A. Bushinsky', 'orcid': 'https://orcid.org/0000-0002-4030-2922'}, 'institutions': [{'id': 'https://openalex.org/I5388228', 'display_name': 'University of Rochester', 'ror': 'https://ror.org/022kthw22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I5388228']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David A. Bushinsky', 'raw_affiliation_strings': ['University of Rochester'], 'affiliations': [{'raw_affiliation_string': 'University of Rochester', 'institution_ids': ['https://openalex.org/I5388228']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077309023', 'display_name': 'John J. Kuiper', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I5388228', 'display_name': 'University of Rochester', 'ror': 'https://ror.org/022kthw22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I5388228']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John J. Kuiper', 'raw_affiliation_strings': ['University of Rochester'], 'affiliations': [{'raw_affiliation_string': 'University of Rochester', 'institution_ids': ['https://openalex.org/I5388228']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.258, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.805567, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 71, 'max': 75}, 'biblio': {'volume': None, 'issue': None, 'first_page': '819', 'last_page': '839'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10606', 'display_name': 'Prevalence and Management of Kidney Stones', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10606', 'display_name': 'Prevalence and Management of Kidney Stones', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10516', 'display_name': 'Mineral Metabolism in Chronic Kidney Disease', 'score': 0.9879, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14415', 'display_name': 'Nephropathic Cystinosis Research', 'score': 0.9855, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chronic-kidney-disease', 'display_name': 'Chronic Kidney Disease', 'score': 0.551241}, {'id': 'https://openalex.org/keywords/mineral-metabolism', 'display_name': 'mineral metabolism', 'score': 0.505778}], 'concepts': [{'id': 'https://openalex.org/C2777724520', 'wikidata': 'https://www.wikidata.org/wiki/Q2526358', 'display_name': 'Hypercalciuria', 'level': 3, 'score': 0.88774747}, {'id': 'https://openalex.org/C2779403450', 'wikidata': 'https://www.wikidata.org/wiki/Q178623', 'display_name': 'Kidney stones', 'level': 2, 'score': 0.6653674}, {'id': 'https://openalex.org/C50440223', 'wikidata': 'https://www.wikidata.org/wiki/Q1475848', 'display_name': 'Risk factor', 'level': 2, 'score': 0.43971798}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4381073}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3968237}, {'id': 'https://openalex.org/C519063684', 'wikidata': 'https://www.wikidata.org/wiki/Q706', 'display_name': 'Calcium', 'level': 2, 'score': 0.08508247}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/b978-0-12-804182-6.00043-5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463230', 'display_name': 'Elsevier eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.85, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 247, 'referenced_works': ['https://openalex.org/W1151991771', 'https://openalex.org/W1234732706', 'https://openalex.org/W1415880306', 'https://openalex.org/W1497442460', 'https://openalex.org/W1506363772', 'https://openalex.org/W1514189471', 'https://openalex.org/W1521596432', 'https://openalex.org/W1527182411', 'https://openalex.org/W1531545141', 'https://openalex.org/W1573088094', 'https://openalex.org/W1592962814', 'https://openalex.org/W164164449', 'https://openalex.org/W1728678547', 'https://openalex.org/W1749200137', 'https://openalex.org/W1757629277', 'https://openalex.org/W1770323589', 'https://openalex.org/W1908638518', 'https://openalex.org/W1924313678', 'https://openalex.org/W19424983', 'https://openalex.org/W1964103204', 'https://openalex.org/W1965018306', 'https://openalex.org/W1965395294', 'https://openalex.org/W1965884067', 'https://openalex.org/W1968071172', 'https://openalex.org/W1969346331', 'https://openalex.org/W1969632516', 'https://openalex.org/W1971491050', 'https://openalex.org/W1972282041', 'https://openalex.org/W1973321166', 'https://openalex.org/W1975528985', 'https://openalex.org/W1975542077', 'https://openalex.org/W1979118414', 'https://openalex.org/W1979265035', 'https://openalex.org/W1979300773', 'https://openalex.org/W1980061532', 'https://openalex.org/W1980755033', 'https://openalex.org/W1982896467', 'https://openalex.org/W1983623022', 'https://openalex.org/W1984960056', 'https://openalex.org/W1986426068', 'https://openalex.org/W1986553563', 'https://openalex.org/W1990395816', 'https://openalex.org/W1990715146', 'https://openalex.org/W1992184194', 'https://openalex.org/W1992214240', 'https://openalex.org/W1993684383', 'https://openalex.org/W1994108378', 'https://openalex.org/W1994555184', 'https://openalex.org/W1996115126', 'https://openalex.org/W1996323871', 'https://openalex.org/W1997614567', 'https://openalex.org/W1999936179', 'https://openalex.org/W1999979428', 'https://openalex.org/W2003306654', 'https://openalex.org/W2004501597', 'https://openalex.org/W2005296604', 'https://openalex.org/W2006079464', 'https://openalex.org/W2006675115', 'https://openalex.org/W2006714232', 'https://openalex.org/W2007932581', 'https://openalex.org/W2012349916', 'https://openalex.org/W2012730812', 'https://openalex.org/W2013540134', 'https://openalex.org/W2013983528', 'https://openalex.org/W2016090102', 'https://openalex.org/W2016434510', 'https://openalex.org/W2018311722', 'https://openalex.org/W2018809127', 'https://openalex.org/W2019817610', 'https://openalex.org/W2021879369', 'https://openalex.org/W2022157009', 'https://openalex.org/W2022854501', 'https://openalex.org/W2024408177', 'https://openalex.org/W2027593655', 'https://openalex.org/W2028715927', 'https://openalex.org/W2029017440', 'https://openalex.org/W2029456267', 'https://openalex.org/W2029724839', 'https://openalex.org/W2031000099', 'https://openalex.org/W2033150037', 'https://openalex.org/W2033184754', 'https://openalex.org/W2033860046', 'https://openalex.org/W2033978181', 'https://openalex.org/W2034131297', 'https://openalex.org/W2034464387', 'https://openalex.org/W2034873907', 'https://openalex.org/W2035469386', 'https://openalex.org/W2037045934', 'https://openalex.org/W2040137593', 'https://openalex.org/W2042242853', 'https://openalex.org/W2044374365', 'https://openalex.org/W2045180107', 'https://openalex.org/W2045218551', 'https://openalex.org/W2045814589', 'https://openalex.org/W2045985723', 'https://openalex.org/W2046425824', 'https://openalex.org/W2047688044', 'https://openalex.org/W2049096000', 'https://openalex.org/W2051261462', 'https://openalex.org/W2052145093', 'https://openalex.org/W2052357540', 'https://openalex.org/W2052362972', 'https://openalex.org/W2052741360', 'https://openalex.org/W2053203718', 'https://openalex.org/W2053215322', 'https://openalex.org/W2053363596', 'https://openalex.org/W2053605231', 'https://openalex.org/W2054475366', 'https://openalex.org/W2054667743', 'https://openalex.org/W2056406453', 'https://openalex.org/W2058624573', 'https://openalex.org/W2058633925', 'https://openalex.org/W2058712110', 'https://openalex.org/W2059134852', 'https://openalex.org/W2059629870', 'https://openalex.org/W2063319857', 'https://openalex.org/W2063930122', 'https://openalex.org/W2064236437', 'https://openalex.org/W2064633413', 'https://openalex.org/W2066098020', 'https://openalex.org/W2067021754', 'https://openalex.org/W2069252593', 'https://openalex.org/W2073026049', 'https://openalex.org/W2073572022', 'https://openalex.org/W2074391886', 'https://openalex.org/W2074516286', 'https://openalex.org/W2074611198', 'https://openalex.org/W2074937635', 'https://openalex.org/W2076550141', 'https://openalex.org/W2076668042', 'https://openalex.org/W2076743215', 'https://openalex.org/W2077227225', 'https://openalex.org/W2079094312', 'https://openalex.org/W2079235616', 'https://openalex.org/W2079412069', 'https://openalex.org/W2079653547', 'https://openalex.org/W2080069677', 'https://openalex.org/W2080377915', 'https://openalex.org/W2080822287', 'https://openalex.org/W2080838084', 'https://openalex.org/W2081063477', 'https://openalex.org/W2081692850', 'https://openalex.org/W2082282584', 'https://openalex.org/W2085674399', 'https://openalex.org/W2086044276', 'https://openalex.org/W2090037204', 'https://openalex.org/W2090091494', 'https://openalex.org/W2090189458', 'https://openalex.org/W2090199552', 'https://openalex.org/W2091598878', 'https://openalex.org/W2091620626', 'https://openalex.org/W2094264348', 'https://openalex.org/W2094524616', 'https://openalex.org/W2095218977', 'https://openalex.org/W2095258939', 'https://openalex.org/W2095462083', 'https://openalex.org/W2095846291', 'https://openalex.org/W2097191932', 'https://openalex.org/W2100311341', 'https://openalex.org/W2100850608', 'https://openalex.org/W2103902496', 'https://openalex.org/W2104028156', 'https://openalex.org/W2105267306', 'https://openalex.org/W2106107456', 'https://openalex.org/W2106174464', 'https://openalex.org/W2108135980', 'https://openalex.org/W2109412104', 'https://openalex.org/W2116323525', 'https://openalex.org/W2120241921', 'https://openalex.org/W2122514015', 'https://openalex.org/W2123339423', 'https://openalex.org/W2124493179', 'https://openalex.org/W2125793849', 'https://openalex.org/W2127392024', 'https://openalex.org/W2127774981', 'https://openalex.org/W2131055961', 'https://openalex.org/W2131098491', 'https://openalex.org/W2132749564', 'https://openalex.org/W2134568924', 'https://openalex.org/W2137855058', 'https://openalex.org/W2139746687', 'https://openalex.org/W2139887800', 'https://openalex.org/W2142522655', 'https://openalex.org/W2142838289', 'https://openalex.org/W2143528414', 'https://openalex.org/W2143902503', 'https://openalex.org/W2146048475', 'https://openalex.org/W2147811836', 'https://openalex.org/W2148196088', 'https://openalex.org/W2148391608', 'https://openalex.org/W2152623396', 'https://openalex.org/W2152765106', 'https://openalex.org/W2153008535', 'https://openalex.org/W2154008507', 'https://openalex.org/W2155000308', 'https://openalex.org/W2156403523', 'https://openalex.org/W2156446545', 'https://openalex.org/W2156861674', 'https://openalex.org/W2157851728', 'https://openalex.org/W2158124838', 'https://openalex.org/W2159021380', 'https://openalex.org/W2172177193', 'https://openalex.org/W2240420452', 'https://openalex.org/W2311505035', 'https://openalex.org/W2315232639', 'https://openalex.org/W2319676870', 'https://openalex.org/W2324111732', 'https://openalex.org/W2326920106', 'https://openalex.org/W2339056788', 'https://openalex.org/W2340504819', 'https://openalex.org/W2396338222', 'https://openalex.org/W2400963829', 'https://openalex.org/W2402046815', 'https://openalex.org/W2406589391', 'https://openalex.org/W2407100223', 'https://openalex.org/W2407229328', 'https://openalex.org/W2408439076', 'https://openalex.org/W2408807883', 'https://openalex.org/W2410346436', 'https://openalex.org/W2410741332', 'https://openalex.org/W2416741509', 'https://openalex.org/W2416796736', 'https://openalex.org/W2467507680', 'https://openalex.org/W2559085435', 'https://openalex.org/W2604350608', 'https://openalex.org/W2642355309', 'https://openalex.org/W2734277417', 'https://openalex.org/W2884738468', 'https://openalex.org/W297609273', 'https://openalex.org/W3188027652', 'https://openalex.org/W323336133', 'https://openalex.org/W37831906', 'https://openalex.org/W4210978414', 'https://openalex.org/W4235877053', 'https://openalex.org/W4244273098', 'https://openalex.org/W4245087881', 'https://openalex.org/W4251485361', 'https://openalex.org/W4252172859', 'https://openalex.org/W4252908838', 'https://openalex.org/W4252975077', 'https://openalex.org/W4253110471', 'https://openalex.org/W4254287399', 'https://openalex.org/W4254539431', 'https://openalex.org/W585327722', 'https://openalex.org/W61318243', 'https://openalex.org/W808077827', 'https://openalex.org/W99539209'], 'related_works': ['https://openalex.org/W827254617', 'https://openalex.org/W4313260479', 'https://openalex.org/W3210214395', 'https://openalex.org/W2971324743', 'https://openalex.org/W2790058814', 'https://openalex.org/W2129413351', 'https://openalex.org/W2068979756', 'https://openalex.org/W2068175549', 'https://openalex.org/W1600771718', 'https://openalex.org/W129591107'], 'abstract_inverted_index': {'Kidney': [0], 'stones': [1, 19], 'are': [2, 166], 'prevalent,': [3], 'cause': [4], 'considerable': [5], 'morbidity': [6], 'though': [7], 'little': [8], 'mortality.': [9], 'The': [10], 'most': [11], 'common': [12], 'metabolic': [13, 26], 'abnormality': [14], 'in': [15, 48, 61, 120, 177, 187, 192], 'patients': [16], 'with': [17], 'kidney': [18, 90, 157], 'is': [20, 23, 29, 59, 70, 92, 129, 160], 'hypercalciuria,': [21], 'which': [22, 56], 'a': [24, 86, 89, 130, 152, 156], 'complex': [25], 'trait': [27], 'that': [28, 149, 162], 'dependent': [30, 93], 'on': [31, 96, 104, 117], 'three': [32], 'major': [33], 'organs:': [34], 'the': [35, 53, 62, 97, 100, 121, 135, 146, 174, 179], 'amount': [36], 'of': [37, 50, 66, 73, 75, 99, 108, 138], 'dietary': [38], 'calcium': [39, 43, 58, 68, 142], 'absorbed,': [40], 'any': [41], 'net': [42], 'released': [44], 'from': [45], 'bone': [46], 'resorption': [47], 'excess': [49], 'formation,': [51, 128], 'and': [52, 77, 82, 114, 116, 125, 184, 191], 'extent': [54], 'to': [55], 'filtered': [57], 'reabsorbed': [60], 'renal': [63], 'tubule.': [64], 'Each': [65], 'these': [67], 'fluxes': [69], 'under': [71], 'control': [72], 'number': [74], 'factors': [76, 119, 148], 'hormones,': [78], 'including': [79, 111], 'parathyroid': [80], 'hormone': [81], '1,25-dihydroxy-vitamin': [83], 'D.': [84], 'Whether': [85], 'patient': [87, 153], 'forms': [88], 'stone': [91, 127, 185], 'not': [94, 139], 'only': [95, 140], 'magnitude': [98], 'hypercalciuria': [101, 183], 'but': [102, 144], 'also': [103, 145], 'urinary': [105, 122], 'volume,': [106], 'excretion': [107], 'other': [109, 147], 'ions,': [110], 'oxalate,': [112], 'citrate,': [113], 'phosphate,': [115], 'local': [118], 'tract.': [123], 'Hypercalciuria,': [124], 'resultant': [126], 'partially': [131], 'inherited': [132], 'trait.': [133], 'Given': [134], 'many': [136], 'determinants': [137], 'urine': [141], 'excretion,': [143], 'determine': [150], 'whether': [151], 'will': [154, 172], 'form': [155], 'stone,': [158], 'it': [159], 'clear': [161], 'multiple': [163], 'genetic': [164, 180], 'loci': [165], 'involved.': [167], 'In': [168], 'this': [169], 'chapter,': [170], 'we': [171], 'describe': [173], 'progress': [175], 'made': [176], 'understanding': [178], 'basis': [181], 'for': [182], 'formation': [186], 'both': [188], 'experimental': [189], 'models': [190], 'man.': [193]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W129591107', 'counts_by_year': [{'year': 2021, 'cited_by_count': 2}], 'updated_date': '2024-09-09T02:42:27.030734', 'created_date': '2016-06-24'}