Title: Acitretin-induced acral hemorrhagic lesions in Darier-White disease.
Abstract: Darier-White disease (DD) is an autosomal-dominant inherited disease characterized by keratotic papules that are usually located in seborrheic areas. Systemic retinoids generally are first-line treatment in cases of diffuse DD. We report the case of an 84-year-old woman with a hypertrophic variant of DD with acral lesions. Oral retinoids (acitretin) were administered as a first treatment of DD, with good clinical results. After a few months, hemorrhagic vesicles developed on palmoplantar surfaces. Suspension of the therapy led to the disappearance of the cutaneous manifestations.
Publication Year: 2014
Publication Date: 2014-12-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 10
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