Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1194966999', 'doi': 'https://doi.org/10.1007/s00228-015-1915-y', 'title': 'Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves', 'display_name': 'Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves', 'publication_year': 2015, 'publication_date': '2015-08-11', 'ids': {'openalex': 'https://openalex.org/W1194966999', 'doi': 'https://doi.org/10.1007/s00228-015-1915-y', 'mag': '1194966999', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26257249'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00228-015-1915-y', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31780008', 'display_name': 'European Journal of Clinical Pharmacology', 'issn_l': '0031-6970', 'issn': ['0031-6970', '1432-1041'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5009378828', 'display_name': 'Jee Eun Chung', 'orcid': 'https://orcid.org/0000-0001-5608-1530'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jee-Eun Chung', 'raw_affiliation_strings': ['College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea', 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057253933', 'display_name': 'Byung‐Chul Chang', 'orcid': 'https://orcid.org/0000-0001-5005-8217'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Byung Chul Chang', 'raw_affiliation_strings': ['Department of Thoracic & Cardiovascular Surgery, Yonsei University Medical Center, Seoul, 120-752, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic & Cardiovascular Surgery, Yonsei University Medical Center, Seoul, 120-752, South Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100398200', 'display_name': 'Kyung Eun Lee', 'orcid': 'https://orcid.org/0000-0002-9535-7314'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Kyung Eun Lee', 'raw_affiliation_strings': ['College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea', 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103377051', 'display_name': 'Joo Hee Kim', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Joo Hee Kim', 'raw_affiliation_strings': ['College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea', 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013866618', 'display_name': 'Hye Sun Gwak', 'orcid': 'https://orcid.org/0000-0003-0278-2563'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hye Sun Gwak', 'raw_affiliation_strings': ['College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayedae-gil, Seodaemun-gu, Seoul, 120-750, South Korea', 'institution_ids': ['https://openalex.org/I138925566']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.909, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.937898, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '71', 'issue': '10', 'first_page': '1229', 'last_page': '1236'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10375', 'display_name': 'Drug Metabolism and Pharmacogenomics', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10375', 'display_name': 'Drug Metabolism and Pharmacogenomics', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11839', 'display_name': 'Management of Primary Aldosteronism', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13004', 'display_name': 'Role of Vitamin K in Health', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/vkorc1', 'display_name': 'VKORC1', 'score': 0.9151734}, {'id': 'https://openalex.org/keywords/vitamin-k', 'display_name': 'Vitamin K', 'score': 0.499276}], 'concepts': [{'id': 'https://openalex.org/C2776318485', 'wikidata': 'https://www.wikidata.org/wiki/Q18045930', 'display_name': 'VKORC1', 'level': 5, 'score': 0.9151734}, {'id': 'https://openalex.org/C2776765323', 'wikidata': 'https://www.wikidata.org/wiki/Q82305736', 'display_name': 'Vitamin K epoxide reductase', 'level': 5, 'score': 0.82800317}, {'id': 'https://openalex.org/C2776301958', 'wikidata': 'https://www.wikidata.org/wiki/Q407431', 'display_name': 'Warfarin', 'level': 3, 'score': 0.658056}, {'id': 'https://openalex.org/C134651460', 'wikidata': 'https://www.wikidata.org/wiki/Q3100717', 'display_name': 'Reductase', 'level': 3, 'score': 0.5555558}, {'id': 'https://openalex.org/C153209595', 'wikidata': 'https://www.wikidata.org/wiki/Q501128', 'display_name': 'Single-nucleotide polymorphism', 'level': 4, 'score': 0.5463881}, {'id': 'https://openalex.org/C75520062', 'wikidata': 'https://www.wikidata.org/wiki/Q15321392', 'display_name': 'NAD+ kinase', 'level': 3, 'score': 0.529458}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.46136776}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4228102}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.40438387}, {'id': 'https://openalex.org/C3946865', 'wikidata': 'https://www.wikidata.org/wiki/Q5014962', 'display_name': 'CYP2C9', 'level': 4, 'score': 0.36693728}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.36391243}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3615442}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.35647774}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3004825}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.28179303}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.20870167}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.18576723}, {'id': 'https://openalex.org/C2779161974', 'wikidata': 'https://www.wikidata.org/wiki/Q815819', 'display_name': 'Atrial fibrillation', 'level': 2, 'score': 0.08525458}], 'mesh': [{'descriptor_ui': 'D016660', 'descriptor_name': 'NAD(P)H Dehydrogenase (Quinone)', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D014859', 'descriptor_name': 'Warfarin', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D014859', 'descriptor_name': 'Warfarin', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D000367', 'descriptor_name': 'Age Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015992', 'descriptor_name': 'Body Mass Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D065729', 'descriptor_name': 'Cytochrome P-450 CYP2C9', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D065729', 'descriptor_name': 'Cytochrome P-450 CYP2C9', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003577', 'descriptor_name': 'Cytochrome P-450 Enzyme System', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003577', 'descriptor_name': 'Cytochrome P-450 Enzyme System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000072470', 'descriptor_name': 'Cytochrome P450 Family 4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004150', 'descriptor_name': 'Dipeptidases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004150', 'descriptor_name': 'Dipeptidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050991', 'descriptor_name': 'GATA4 Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D050991', 'descriptor_name': 'GATA4 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005787', 'descriptor_name': 'Gene Frequency', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005838', 'descriptor_name': 'Genotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006350', 'descriptor_name': 'Heart Valve Prosthesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016660', 'descriptor_name': 'NAD(P)H Dehydrogenase (Quinone)', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020641', 'descriptor_name': 'Polymorphism, Single Nucleotide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056910', 'descriptor_name': 'Republic of Korea', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012737', 'descriptor_name': 'Sex Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064417', 'descriptor_name': 'Vitamin K Epoxide Reductases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D064417', 'descriptor_name': 'Vitamin K Epoxide Reductases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014859', 'descriptor_name': 'Warfarin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00228-015-1915-y', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31780008', 'display_name': 'European Journal of Clinical Pharmacology', 'issn_l': '0031-6970', 'issn': ['0031-6970', '1432-1041'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26257249', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1523565294', 'https://openalex.org/W1545314652', 'https://openalex.org/W1969497645', 'https://openalex.org/W1977280638', 'https://openalex.org/W2013009060', 'https://openalex.org/W2024621619', 'https://openalex.org/W2025527247', 'https://openalex.org/W2026697437', 'https://openalex.org/W2046584656', 'https://openalex.org/W2055686515', 'https://openalex.org/W2058536932', 'https://openalex.org/W2093502239', 'https://openalex.org/W2094077411', 'https://openalex.org/W2100876297', 'https://openalex.org/W2112940339', 'https://openalex.org/W2121152339', 'https://openalex.org/W2123719025', 'https://openalex.org/W2127138010', 'https://openalex.org/W2128189669', 'https://openalex.org/W2138980150', 'https://openalex.org/W2142751427', 'https://openalex.org/W2152664025', 'https://openalex.org/W2157839219', 'https://openalex.org/W2161564051', 'https://openalex.org/W2315457142', 'https://openalex.org/W4210383178', 'https://openalex.org/W4238924478'], 'related_works': ['https://openalex.org/W4287377228', 'https://openalex.org/W3016007536', 'https://openalex.org/W2729913079', 'https://openalex.org/W2398504558', 'https://openalex.org/W2348055743', 'https://openalex.org/W2147207746', 'https://openalex.org/W2046589790', 'https://openalex.org/W2014927292', 'https://openalex.org/W2010116601', 'https://openalex.org/W1766982027'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1194966999', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}], 'updated_date': '2024-09-10T18:41:43.778532', 'created_date': '2016-06-24'}