Publication Information

{'id': 'https://openalex.org/W1194056033', 'doi': 'https://doi.org/10.18632/oncotarget.4407', 'title': 'miR-454 functions as an oncogene by inhibiting CHD5 in hepatocellular carcinoma', 'display_name': 'miR-454 functions as an oncogene by inhibiting CHD5 in hepatocellular carcinoma', 'publication_year': 2015, 'publication_date': '2015-07-30', 'ids': {'openalex': 'https://openalex.org/W1194056033', 'doi': 'https://doi.org/10.18632/oncotarget.4407', 'mag': '1194056033', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26287602', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4770768'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.4407', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=4407&path%5B%5D=16091', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=4407&path%5B%5D=16091', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100662885', 'display_name': 'Lei Yu', 'orcid': 'https://orcid.org/0000-0002-8837-2022'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lei Yu', 'raw_affiliation_strings': ['Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.', 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5104129040', 'display_name': 'Xuejun Gong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210159865', 'display_name': 'Xiangya Hospital Central South University', 'ror': 'https://ror.org/05c1yfj14', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159865']}, {'id': 'https://openalex.org/I139660479', 'display_name': 'Central South University', 'ror': 'https://ror.org/00f1zfq44', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I139660479']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xuejun Gong', 'raw_affiliation_strings': ['Department of Biliary and Pancreatic Surgery, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Biliary and Pancreatic Surgery, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China', 'institution_ids': ['https://openalex.org/I4210159865', 'https://openalex.org/I139660479']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019343725', 'display_name': 'Lei Sun', 'orcid': 'https://orcid.org/0000-0001-7230-7640'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}, {'id': 'https://openalex.org/I4210122309', 'display_name': 'Fourth Affiliated Hospital of Harbin Medical University', 'ror': 'https://ror.org/02s7c9e98', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122309']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lei Sun', 'raw_affiliation_strings': ['Department of Ophthalmology, The Fourth Hospital of Harbin Medical University, Harbin 150001, Heilongjiang, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, The Fourth Hospital of Harbin Medical University, Harbin 150001, Heilongjiang, China', 'institution_ids': ['https://openalex.org/I156144747', 'https://openalex.org/I4210122309']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101151232', 'display_name': 'Hong Yao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hong Yao', 'raw_affiliation_strings': ['Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.', 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073240502', 'display_name': 'Baoling Lu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Baoling Lu', 'raw_affiliation_strings': ['Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.', 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5065034761', 'display_name': 'Liying Zhu', 'orcid': 'https://orcid.org/0000-0003-1060-4337'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Liying Zhu', 'raw_affiliation_strings': ['Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.', 'institution_ids': ['https://openalex.org/I156144747']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.49, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 52, 'citation_normalized_percentile': {'value': 0.704852, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '6', 'issue': '36', 'first_page': '39225', 'last_page': '39234'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.8797423}, {'id': 'https://openalex.org/C2781018059', 'wikidata': 'https://www.wikidata.org/wiki/Q207609', 'display_name': 'Oncogene', 'level': 4, 'score': 0.76794994}, {'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.7048286}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.614272}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.6021413}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.54733485}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.53374565}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.46482423}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.41911244}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.37936267}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.36409083}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3478711}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3089596}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.16904789}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.15151522}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.093955934}], 'mesh': [{'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058750', 'descriptor_name': 'Epithelial-Mesenchymal Transition', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056945', 'descriptor_name': 'Hep G2 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009857', 'descriptor_name': 'Oncogenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.4407', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=4407&path%5B%5D=16091', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4770768', 'pdf_url': 'https://europepmc.org/articles/pmc4770768?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770768', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26287602', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.4407', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=4407&path%5B%5D=16091', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.77}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W108551223', 'https://openalex.org/W116770130', 'https://openalex.org/W1489663513', 'https://openalex.org/W1523297072', 'https://openalex.org/W1551199774', 'https://openalex.org/W1555776512', 'https://openalex.org/W1596996643', 'https://openalex.org/W1608421996', 'https://openalex.org/W1642946927', 'https://openalex.org/W173881836', 'https://openalex.org/W1835838039', 'https://openalex.org/W1844690031', 'https://openalex.org/W1965147750', 'https://openalex.org/W1970377986', 'https://openalex.org/W1971320728', 'https://openalex.org/W1974469992', 'https://openalex.org/W1986787670', 'https://openalex.org/W1993112284', 'https://openalex.org/W1994493099', 'https://openalex.org/W2010918771', 'https://openalex.org/W2017603097', 'https://openalex.org/W2018503586', 'https://openalex.org/W2023987874', 'https://openalex.org/W2034069169', 'https://openalex.org/W2039140363', 'https://openalex.org/W2042961442', 'https://openalex.org/W2043345218', 'https://openalex.org/W2045554354', 'https://openalex.org/W2046467581', 'https://openalex.org/W2057392060', 'https://openalex.org/W2061694790', 'https://openalex.org/W2075066001', 'https://openalex.org/W2082501223', 'https://openalex.org/W2086134602', 'https://openalex.org/W2088416146', 'https://openalex.org/W2097494801', 'https://openalex.org/W2110257299', 'https://openalex.org/W2114151839', 'https://openalex.org/W2130730618', 'https://openalex.org/W2149818581', 'https://openalex.org/W2162463195', 'https://openalex.org/W2167325961', 'https://openalex.org/W2252647763', 'https://openalex.org/W2317361272', 'https://openalex.org/W2323982005', 'https://openalex.org/W2335671353', 'https://openalex.org/W2398392409', 'https://openalex.org/W2407131164', 'https://openalex.org/W2412229812'], 'related_works': ['https://openalex.org/W4386799875', 'https://openalex.org/W4247833810', 'https://openalex.org/W4242240318', 'https://openalex.org/W4213065871', 'https://openalex.org/W3127487613', 'https://openalex.org/W3103789129', 'https://openalex.org/W3048105303', 'https://openalex.org/W3036801227', 'https://openalex.org/W2904239912', 'https://openalex.org/W1968932537'], 'abstract_inverted_index': {'//': [0], 'Lei': [1, 11, 88], 'Yu': [2], '1,': [3], '*': [4, 9, 74], ',': [5, 10, 14, 18, 22], 'Xuejun': [6], 'Gong': [7], '2,': [8], 'Sun': [12], '3': [13, 59], 'Hong': [15], 'Yao': [16], '1': [17, 21, 25, 26], 'Baoling': [19], 'Lu': [20], 'Liying': [23], 'Zhu': [24], 'Department': [27, 43, 60], 'of': [28, 34, 44, 51, 61, 66, 149, 164, 183, 198, 206, 214, 219], 'Infectious': [29], 'Disease,': [30], 'The': [31, 63], 'Fourth': [32, 64], 'Hospital': [33, 50, 65], 'Harbin': [35, 38, 67, 70], 'Medical': [36, 68], 'University,': [37, 54, 69], '150001,': [39, 71], 'Heilongjiang,': [40, 72], 'China': [41, 58, 73], '2': [42], 'Biliary': [45], 'and': [46, 146, 155, 157, 170, 172, 191, 194], 'Pancreatic': [47], 'Surgery,': [48], 'Xiangya': [49], 'Central': [52], 'South': [53], 'Changsha,': [55], '410008,': [56], 'Hunan,': [57], 'Ophthalmology,': [62], 'These': [75], 'authors': [76], 'contributed': [77], 'equally': [78], 'to': [79], 'this': [80, 133], 'work': [81], 'Correspondence': [82], 'to:': [83], 'Li-Ying': [84], 'Zhu,': [85], 'e-mail:': [86, 90], '[email protected]': [87], 'Yu,': [89], '[email protected]': [91], 'Keywords:': [92], 'hepatocellular': [93], 'carcinoma,': [94], 'microRNA,': [95], 'miR-454,': [96], 'CHD5': [97, 178, 185, 199], 'Received:': [98], 'May': [99], '11,': [100], '2015     ': [101, 105], 'Accepted:': [102], 'July': [103, 107], '17,': [104], 'Published:': [106], '30,': [108], '2015': [109], 'ABSTRACT': [110], 'Previous': [111], 'studies': [112], 'showed': [113], 'that': [114, 137, 230], 'miR-454': [115, 138, 150, 165, 207, 215, 231], 'acted': [116], 'as': [117, 179, 233], 'an': [118, 234], 'oncogene': [119, 235], 'or': [120], 'tumor': [121], 'suppressor': [122], 'in': [123, 128, 142, 188, 208, 222, 236], 'cancer.': [124], 'However,': [125], 'its': [126], 'function': [127], 'HCC': [129, 143, 152, 167, 189, 209], 'remains': [130], 'unknown.': [131], 'In': [132, 211], 'study,': [134], 'we': [135, 175], 'found': [136], 'expression': [139, 196, 205], 'was': [140, 186, 200], 'upregulated': [141], 'cell': [144, 153, 168, 192], 'lines': [145, 193], 'tissues.': [147, 210], 'Knockdown': [148], 'inhibited': [151, 216], 'proliferation': [154, 169], 'invasion': [156, 171], 'epithelial': [158], 'mesenchymal': [159], 'transition': [160], '(EMT),': [161], 'whereas': [162], 'overexpression': [163], 'promoted': [166], 'EMT.': [173], 'Furthermore,': [174], 'identified': [176], 'the': [177, 195, 204, 217], 'a': [180], 'direct': [181], 'target': [182], 'miR-454.': [184], 'downregulated': [187], 'tissues': [190], 'level': [197], 'inversely': [201], 'correlated': [202], 'with': [203], 'addition,': [212], 'knockdown': [213], 'growth': [218], 'HepG2-engrafted': [220], 'tumors': [221], 'vivo': [223], '.': [224], 'Taken': [225], 'together,': [226], 'these': [227], 'results': [228], 'indicated': [229], 'functioned': [232], 'HCC.': [237]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1194056033', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 14}, {'year': 2016, 'cited_by_count': 7}], 'updated_date': '2024-12-13T19:48:37.134701', 'created_date': '2016-06-24'}