Title: Остаточные риски трансфузионно-трансмиссивной передачи ВИЧ-инфекции и вирусного гепатита c в Московском регионе при лабораторном скрининге донорской крови с использованием NAT-технологий
Abstract: Serological and NAT-methods used for blood screening have a limit of detection, that does not eliminate the risk of blood transfusion transmitted infections (TTIs). The residual risk of TTIs allows evaluating the effectiveness of new blood screening methods. The residual risk of TTIs was calculated with a math model incidence rate/window period and was 3.2 for HIV and 13.35 for hepatitis C virus (HCV) per 1 million of donations. This study was performed on a small sample (412028 donations), so the results can be extrapolated only to the Moscow region, and are not representative for other regions of Russia. The rate of residual risk of HIV and HCV is higher than in other countries because of donor infection. Obligatory NAT testing of blood samples of all donations by highly sensitive test systems is expected to reduce the risk of TTI.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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