Title: Prognostic Analysis of Three-Dimensional Conformal Radiotherapy of Regional Lymph Node Metastasis of the Surgical Esophageal Carcinoma Patients After Resection
Abstract: Objectives. To investigate the prognostic factors of three-dimensional conformal radiotherapy (3D-CRT ) of regional metastatic lymph nodes of the esophageal surgical carcinoma patients. Methods. In this study we collected ninety patients with pathology-confirmed esophageal carcinoma by resection specimens, who received radical 3D-CRT due to recurrence and/or metastasis lymph nodes. The prescription dose of those seventy-nine patients who received whole range 3-DCRT was 50~72Gy/25~36F. The other 11 cases received traditional conventional radiotherapy before 3D-CRT, and the total dose was 50~76Gy/25~38F. Results The 1-, 3-, 5-years survival rate after resection were 85.71%, 34.34%, 14.92% respectively. The 1-, 2-, 3-years survival rate was 43.41%, 18.09%, 7.81% respectively after treatment by 3D-CRT due to recurrence and/or lymph node metastasis. The primary tumor length, the X-ray visualization length, tumor stage, the number of metastatic lymph node, the lymph node metastasis time and the lymph node ratio (LNR) were significantly associated with the long-term survival after resection. The TNM stage, the maximum diameter and the diminution extent of metastatic lymph node, the occurring metastasis time, the early efficacy of radiotherapy and the presence of irradiation induced pneumonia were significantly associated with survival rate after radiotherapy. Conclusions. The lower the lungs V35 was, the earlier efficacy presented after radiotherapy. The bigger the diminution extent of metastatic lymph node was, the longer the survival rate was after radiotherapy.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot