Publication Information

{'id': 'https://openalex.org/W1150107472', 'doi': 'https://doi.org/10.1089/ten.teb.2013.0377', 'title': 'The Roles of Catabolic Factors in the Development of Osteoarthritis', 'display_name': 'The Roles of Catabolic Factors in the Development of Osteoarthritis', 'publication_year': 2013, 'publication_date': '2013-10-31', 'ids': {'openalex': 'https://openalex.org/W1150107472', 'doi': 'https://doi.org/10.1089/ten.teb.2013.0377', 'mag': '1150107472', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24172137', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4123463'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/ten.teb.2013.0377', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S13647896', 'display_name': 'Tissue Engineering Part B Reviews', 'issn_l': '1937-3368', 'issn': ['1937-3368', '1937-3376'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc4123463?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5115588423', 'display_name': 'Dominick J. Blasioli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dominick J. Blasioli', 'raw_affiliation_strings': ['Science and Technology Center, Tufts University , Medford, Massachusetts.'], 'affiliations': [{'raw_affiliation_string': 'Science and Technology Center, Tufts University , Medford, Massachusetts.', 'institution_ids': ['https://openalex.org/I121934306']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5057871048', 'display_name': 'David L. Kaplan', 'orcid': 'https://orcid.org/0000-0002-9245-7774'}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David L. Kaplan', 'raw_affiliation_strings': ['Science and Technology Center, Tufts University, Medford, Massachusetts.'], 'affiliations': [{'raw_affiliation_string': 'Science and Technology Center, Tufts University, Medford, Massachusetts.', 'institution_ids': ['https://openalex.org/I121934306']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.751, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 79, 'citation_normalized_percentile': {'value': 0.600785, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '20', 'issue': '4', 'first_page': '355', 'last_page': '363'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10105', 'display_name': 'Osteoarthritis Treatment and Mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10105', 'display_name': 'Osteoarthritis Treatment and Mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 0.9934, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10620', 'display_name': 'Protease and Inhibitor Mechanisms', 'score': 0.9885, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/joint-disease', 'display_name': 'Joint disease', 'score': 0.582636}, {'id': 'https://openalex.org/keywords/adamts', 'display_name': 'ADAMTS', 'score': 0.4183952}], 'concepts': [{'id': 'https://openalex.org/C2776164576', 'wikidata': 'https://www.wikidata.org/wiki/Q62736', 'display_name': 'Osteoarthritis', 'level': 3, 'score': 0.9025976}, {'id': 'https://openalex.org/C2776268809', 'wikidata': 'https://www.wikidata.org/wiki/Q25581', 'display_name': 'Synovial fluid', 'level': 4, 'score': 0.7887504}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5935437}, {'id': 'https://openalex.org/C3017807761', 'wikidata': 'https://www.wikidata.org/wiki/Q708176', 'display_name': 'Joint disease', 'level': 4, 'score': 0.582636}, {'id': 'https://openalex.org/C2780550940', 'wikidata': 'https://www.wikidata.org/wiki/Q502730', 'display_name': 'Cartilage', 'level': 2, 'score': 0.57385963}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.49518195}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.45699164}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.44747138}, {'id': 'https://openalex.org/C13373296', 'wikidata': 'https://www.wikidata.org/wiki/Q421866', 'display_name': 'Chemokine', 'level': 3, 'score': 0.4415138}, {'id': 'https://openalex.org/C2776224515', 'wikidata': 'https://www.wikidata.org/wiki/Q102253084', 'display_name': 'ADAMTS', 'level': 5, 'score': 0.4183952}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.38934335}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.31765878}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.23919848}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.20972958}, {'id': 'https://openalex.org/C109523444', 'wikidata': 'https://www.wikidata.org/wiki/Q424216', 'display_name': 'Matrix metalloproteinase', 'level': 2, 'score': 0.19971982}, {'id': 'https://openalex.org/C167814343', 'wikidata': 'https://www.wikidata.org/wiki/Q419341', 'display_name': 'Thrombospondin', 'level': 4, 'score': 0.1468578}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.07376701}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.05150777}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C55728118', 'wikidata': 'https://www.wikidata.org/wiki/Q425402', 'display_name': 'Metalloproteinase', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D053590', 'descriptor_name': 'Interleukin 1 Receptor Antagonist Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D053583', 'descriptor_name': 'Interleukin-1beta', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010003', 'descriptor_name': 'Osteoarthritis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013582', 'descriptor_name': 'Synovial Fluid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053590', 'descriptor_name': 'Interleukin 1 Receptor Antagonist Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053583', 'descriptor_name': 'Interleukin-1beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010003', 'descriptor_name': 'Osteoarthritis', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D010003', 'descriptor_name': 'Osteoarthritis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013582', 'descriptor_name': 'Synovial Fluid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/ten.teb.2013.0377', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S13647896', 'display_name': 'Tissue Engineering Part B Reviews', 'issn_l': '1937-3368', 'issn': ['1937-3368', '1937-3376'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4123463', 'pdf_url': 'https://europepmc.org/articles/pmc4123463?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123463', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24172137', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4123463', 'pdf_url': 'https://europepmc.org/articles/pmc4123463?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.54, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 110, 'referenced_works': ['https://openalex.org/W120389314', 'https://openalex.org/W1220034274', 'https://openalex.org/W132651321', 'https://openalex.org/W1514081838', 'https://openalex.org/W1516892952', 'https://openalex.org/W1552444104', 'https://openalex.org/W1670891845', 'https://openalex.org/W1815831370', 'https://openalex.org/W1840567140', 'https://openalex.org/W1849537180', 'https://openalex.org/W1878525374', 'https://openalex.org/W1963315781', 'https://openalex.org/W1965307247', 'https://openalex.org/W1969182658', 'https://openalex.org/W1975690515', 'https://openalex.org/W1976133234', 'https://openalex.org/W1979729579', 'https://openalex.org/W1979972616', 'https://openalex.org/W1980220254', 'https://openalex.org/W1983345459', 'https://openalex.org/W1983374705', 'https://openalex.org/W1983541797', 'https://openalex.org/W1988674295', 'https://openalex.org/W1990844960', 'https://openalex.org/W1992797444', 'https://openalex.org/W1997027978', 'https://openalex.org/W1997957358', 'https://openalex.org/W2000165895', 'https://openalex.org/W2008430756', 'https://openalex.org/W2011957687', 'https://openalex.org/W2012064275', 'https://openalex.org/W2012827463', 'https://openalex.org/W2014587146', 'https://openalex.org/W2015367871', 'https://openalex.org/W2016578394', 'https://openalex.org/W2016664601', 'https://openalex.org/W2017720269', 'https://openalex.org/W2017783831', 'https://openalex.org/W2022640830', 'https://openalex.org/W2023669928', 'https://openalex.org/W2027458529', 'https://openalex.org/W2028149799', 'https://openalex.org/W2030084808', 'https://openalex.org/W2030821405', 'https://openalex.org/W2033701197', 'https://openalex.org/W2035423607', 'https://openalex.org/W2039799680', 'https://openalex.org/W2041325252', 'https://openalex.org/W2042469661', 'https://openalex.org/W2044762171', 'https://openalex.org/W2047636197', 'https://openalex.org/W2050178836', 'https://openalex.org/W2053342448', 'https://openalex.org/W2054693438', 'https://openalex.org/W2055361189', 'https://openalex.org/W2056813079', 'https://openalex.org/W2057491978', 'https://openalex.org/W2058972817', 'https://openalex.org/W2062522737', 'https://openalex.org/W2066659898', 'https://openalex.org/W2071957299', 'https://openalex.org/W2072199684', 'https://openalex.org/W2076413757', 'https://openalex.org/W2079295507', 'https://openalex.org/W2082829228', 'https://openalex.org/W2084195055', 'https://openalex.org/W2084855318', 'https://openalex.org/W2085096893', 'https://openalex.org/W2085314940', 'https://openalex.org/W2085711413', 'https://openalex.org/W2087193732', 'https://openalex.org/W2089605568', 'https://openalex.org/W2090014315', 'https://openalex.org/W2101776443', 'https://openalex.org/W2102664210', 'https://openalex.org/W2103145683', 'https://openalex.org/W2103152132', 'https://openalex.org/W2103819978', 'https://openalex.org/W2112540866', 'https://openalex.org/W2113503012', 'https://openalex.org/W2116450468', 'https://openalex.org/W2118566351', 'https://openalex.org/W2121719530', 'https://openalex.org/W2124093961', 'https://openalex.org/W2133915381', 'https://openalex.org/W2137468010', 'https://openalex.org/W2144351693', 'https://openalex.org/W2148041105', 'https://openalex.org/W2152214101', 'https://openalex.org/W2162156168', 'https://openalex.org/W2164804018', 'https://openalex.org/W2167792025', 'https://openalex.org/W2206659032', 'https://openalex.org/W2400928874', 'https://openalex.org/W2405787708', 'https://openalex.org/W2413293685', 'https://openalex.org/W2414385626', 'https://openalex.org/W2414683055', 'https://openalex.org/W2417725630', 'https://openalex.org/W2419065607', 'https://openalex.org/W2467650495', 'https://openalex.org/W2610860323', 'https://openalex.org/W271228137', 'https://openalex.org/W4232207946', 'https://openalex.org/W4232900352', 'https://openalex.org/W4232925012', 'https://openalex.org/W4238039085', 'https://openalex.org/W4246921342', 'https://openalex.org/W42747587', 'https://openalex.org/W54520268'], 'related_works': ['https://openalex.org/W4206330498', 'https://openalex.org/W2775655997', 'https://openalex.org/W2579312168', 'https://openalex.org/W2374355452', 'https://openalex.org/W2076104046', 'https://openalex.org/W2011227409', 'https://openalex.org/W1976442568', 'https://openalex.org/W1825495148', 'https://openalex.org/W1564431302', 'https://openalex.org/W1150107472'], 'abstract_inverted_index': {'Osteoarthritis': [0], '(OA)': [1], 'is': [2], 'the': [3, 63, 76, 81, 94, 99, 104, 128, 138, 168, 182, 185], 'most': [4], 'prevalent': [5], 'disease': [6, 172], 'of': [7, 22, 37, 49, 69, 75, 86, 93, 106, 127, 170, 184], 'articular': [8], 'joints': [9], 'characterized': [10], 'by': [11, 73], 'joint': [12, 17, 23], 'space': [13], 'narrowing': [14], 'on': [15], 'X-ray,': [16], 'pain,': [18], 'and': [19, 29, 116, 147, 180], 'a': [20, 60], 'loss': [21], 'function': [24], 'through': [25], 'progressive': [26], 'cartilage': [27], 'degradation': [28], 'intermittent': [30], 'synovial': [31, 101, 140], 'inflammation.': [32], 'Current': [33], 'in': [34, 62, 77, 98, 122, 131, 137, 167], 'vitro': [35, 78, 123], 'models': [36, 149], 'OA': [38, 70, 100, 107, 132, 139, 162], 'are': [39], 'often': [40], 'monolayer': [41], 'cultured': [42], 'primary': [43], 'cells': [44], 'exposed': [45], 'to': [46, 124, 151, 173, 176], 'high': [47, 91], 'concentrations': [48, 92, 135], 'cytokines': [50], 'or': [51, 55, 66, 83], 'chemokines,': [52], 'usually': [53], 'IL-1β': [54, 57, 88], 'TNF-α.': [56], 'could': [58], 'play': [59], 'role': [61], 'early': [64, 164], 'progression': [65, 169], 'even': [67], 'initiation': [68, 183], 'as': [71, 163, 165], 'evidenced': [72], 'many': [74, 126], 'studies.': [79], 'However,': [80], 'inconsistent': [82], 'outright': [84], 'lack': [85], 'detectable': [87], 'combined': [89], 'with': [90, 144, 159, 161], 'natural': [95], 'inhibitor': [96], 'IL-1Ra': [97], 'fluid': [102], 'makes': [103], 'idea': [105], 'being': [108], 'IL-1β-driven': [109], 'questionable.': [110], 'Further,': [111], 'other': [112], 'stimulants,': [113], 'including': [114], 'IL-6': [115], 'matrix': [117], 'fragments,': [118], 'have': [119], 'been': [120], 'shown': [121], 'cause': [125], 'effects': [129], 'seen': [130], 'at': [133], 'relevant': [134], 'found': [136], 'fluid.': [141], 'More': [142], 'work': [143], 'these': [145], 'stimulants': [146], 'IL-1β-independent': [148], 'needs': [150], 'be': [152, 157, 174], 'done.': [153], 'Concurrently,': [154], 'research': [155], 'should': [156], 'conducted': [158], 'patients': [160], 'possible': [166], 'their': [171], 'able': [175], 'potentially': [177], 'identify,': [178], 'target,': [179], 'treat': [181], 'disease.': [186]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1150107472', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 16}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 5}], 'updated_date': '2024-12-24T16:45:03.386230', 'created_date': '2016-06-24'}