Publication Information

{'id': 'https://openalex.org/W1122889353', 'doi': 'https://doi.org/10.1128/9781555815493.ch2', 'title': 'Entry Inhibitors of Human Immunodeficiency Virus', 'display_name': 'Entry Inhibitors of Human Immunodeficiency Virus', 'publication_year': 2014, 'publication_date': '2014-04-30', 'ids': {'openalex': 'https://openalex.org/W1122889353', 'doi': 'https://doi.org/10.1128/9781555815493.ch2', 'mag': '1122889353'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/9781555815493.ch2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306462867', 'display_name': 'ASM Press eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'book-chapter', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080592581', 'display_name': 'Masanori Baba', 'orcid': 'https://orcid.org/0000-0002-6109-5248'}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Masanori Baba', 'raw_affiliation_strings': ['Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890 8544, Japan'], 'affiliations': [{'raw_affiliation_string': 'Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890 8544, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5080592581'], 'corresponding_institution_ids': ['https://openalex.org/I107139324'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': None, 'issue': None, 'first_page': '19', 'last_page': '32'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10082', 'display_name': 'HIV/AIDS Research and Interventions', 'score': 0.9821, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/maraviroc', 'display_name': 'Maraviroc', 'score': 0.9308496}, {'id': 'https://openalex.org/keywords/v3-loop', 'display_name': 'V3 loop', 'score': 0.76195025}, {'id': 'https://openalex.org/keywords/entry-inhibitor', 'display_name': 'Entry inhibitor', 'score': 0.71144736}, {'id': 'https://openalex.org/keywords/ccr5-receptor-antagonist', 'display_name': 'CCR5 receptor antagonist', 'score': 0.69862247}, {'id': 'https://openalex.org/keywords/enfuvirtide', 'display_name': 'Enfuvirtide', 'score': 0.591199}], 'concepts': [{'id': 'https://openalex.org/C2778899366', 'wikidata': 'https://www.wikidata.org/wiki/Q421369', 'display_name': 'Maraviroc', 'level': 3, 'score': 0.9308496}, {'id': 'https://openalex.org/C2779921545', 'wikidata': 'https://www.wikidata.org/wiki/Q12085358', 'display_name': 'V3 loop', 'level': 4, 'score': 0.76195025}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.7479275}, {'id': 'https://openalex.org/C2776997796', 'wikidata': 'https://www.wikidata.org/wiki/Q1345259', 'display_name': 'Entry inhibitor', 'level': 5, 'score': 0.71144736}, {'id': 'https://openalex.org/C37044404', 'wikidata': 'https://www.wikidata.org/wiki/Q5009692', 'display_name': 'CCR5 receptor antagonist', 'level': 5, 'score': 0.69862247}, {'id': 'https://openalex.org/C58475186', 'wikidata': 'https://www.wikidata.org/wiki/Q4118894', 'display_name': 'Viral entry', 'level': 4, 'score': 0.5967556}, {'id': 'https://openalex.org/C2778037500', 'wikidata': 'https://www.wikidata.org/wiki/Q423327', 'display_name': 'Enfuvirtide', 'level': 5, 'score': 0.591199}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.5872902}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.5438607}, {'id': 'https://openalex.org/C140704245', 'wikidata': 'https://www.wikidata.org/wiki/Q3933202', 'display_name': 'Viral replication', 'level': 3, 'score': 0.5069037}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.48009804}, {'id': 'https://openalex.org/C97380033', 'wikidata': 'https://www.wikidata.org/wiki/Q994215', 'display_name': 'Viral envelope', 'level': 3, 'score': 0.4316787}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.4046308}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.3917072}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.29532877}, {'id': 'https://openalex.org/C195616568', 'wikidata': 'https://www.wikidata.org/wiki/Q128711', 'display_name': 'Epitope', 'level': 3, 'score': 0.28583354}, {'id': 'https://openalex.org/C2776258796', 'wikidata': 'https://www.wikidata.org/wiki/Q5590520', 'display_name': 'Gp41', 'level': 4, 'score': 0.19970447}, {'id': 'https://openalex.org/C12823836', 'wikidata': 'https://www.wikidata.org/wiki/Q24720618', 'display_name': 'Chemokine receptor', 'level': 4, 'score': 0.09212056}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.0886085}, {'id': 'https://openalex.org/C13373296', 'wikidata': 'https://www.wikidata.org/wiki/Q421866', 'display_name': 'Chemokine', 'level': 3, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/9781555815493.ch2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306462867', 'display_name': 'ASM Press eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 106, 'referenced_works': ['https://openalex.org/W1537640815', 'https://openalex.org/W1966393705', 'https://openalex.org/W1966515400', 'https://openalex.org/W1974543288', 'https://openalex.org/W1986531110', 'https://openalex.org/W1988116237', 'https://openalex.org/W1988157903', 'https://openalex.org/W1991735339', 'https://openalex.org/W1996641092', 'https://openalex.org/W1997989849', 'https://openalex.org/W1999048558', 'https://openalex.org/W2003239995', 'https://openalex.org/W2005780220', 'https://openalex.org/W2005963291', 'https://openalex.org/W2005980845', 'https://openalex.org/W2007021820', 'https://openalex.org/W2010638326', 'https://openalex.org/W2017551575', 'https://openalex.org/W2020933095', 'https://openalex.org/W2021008862', 'https://openalex.org/W2021877795', 'https://openalex.org/W2024383984', 'https://openalex.org/W2026444780', 'https://openalex.org/W2027738518', 'https://openalex.org/W2028309086', 'https://openalex.org/W2032091598', 'https://openalex.org/W2033757712', 'https://openalex.org/W2034073194', 'https://openalex.org/W2036656105', 'https://openalex.org/W2039244520', 'https://openalex.org/W2040015246', 'https://openalex.org/W2040506631', 'https://openalex.org/W2043448829', 'https://openalex.org/W2044004371', 'https://openalex.org/W2046716698', 'https://openalex.org/W2050977299', 'https://openalex.org/W2051785641', 'https://openalex.org/W2057461438', 'https://openalex.org/W2057550019', 'https://openalex.org/W2057633014', 'https://openalex.org/W2063701397', 'https://openalex.org/W2070990188', 'https://openalex.org/W2071189977', 'https://openalex.org/W2071381113', 'https://openalex.org/W2076349085', 'https://openalex.org/W2079517309', 'https://openalex.org/W2081769332', 'https://openalex.org/W2089501828', 'https://openalex.org/W2090630729', 'https://openalex.org/W2094115571', 'https://openalex.org/W2094180923', 'https://openalex.org/W2095780507', 'https://openalex.org/W2096451161', 'https://openalex.org/W2096649016', 'https://openalex.org/W2100805409', 'https://openalex.org/W2103831221', 'https://openalex.org/W2104897321', 'https://openalex.org/W2105607249', 'https://openalex.org/W2108256128', 'https://openalex.org/W2110838631', 'https://openalex.org/W2112129496', 'https://openalex.org/W2117307765', 'https://openalex.org/W2117378263', 'https://openalex.org/W2117394497', 'https://openalex.org/W2120064320', 'https://openalex.org/W2120305713', 'https://openalex.org/W2121138614', 'https://openalex.org/W2125413693', 'https://openalex.org/W2128618062', 'https://openalex.org/W2129106897', 'https://openalex.org/W2132294567', 'https://openalex.org/W2133649749', 'https://openalex.org/W2135581465', 'https://openalex.org/W2135739941', 'https://openalex.org/W2135781036', 'https://openalex.org/W2138802639', 'https://openalex.org/W2139502307', 'https://openalex.org/W2140478082', 'https://openalex.org/W2142655367', 'https://openalex.org/W2143360782', 'https://openalex.org/W2146478787', 'https://openalex.org/W2147169218', 'https://openalex.org/W2147907744', 'https://openalex.org/W2150549563', 'https://openalex.org/W2150833007', 'https://openalex.org/W2150898533', 'https://openalex.org/W2155676461', 'https://openalex.org/W2155737863', 'https://openalex.org/W2155892284', 'https://openalex.org/W2156764168', 'https://openalex.org/W2160767768', 'https://openalex.org/W2161911309', 'https://openalex.org/W2164585544', 'https://openalex.org/W2165690748', 'https://openalex.org/W2170748261', 'https://openalex.org/W2171588267', 'https://openalex.org/W2184573054', 'https://openalex.org/W2292465217', 'https://openalex.org/W2312642584', 'https://openalex.org/W2340606985', 'https://openalex.org/W2399469531', 'https://openalex.org/W2415009490', 'https://openalex.org/W2416039323', 'https://openalex.org/W3144557428', 'https://openalex.org/W4236479494', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W3032424987', 'https://openalex.org/W2684946769', 'https://openalex.org/W2164681352', 'https://openalex.org/W2146506618', 'https://openalex.org/W2072482781', 'https://openalex.org/W2059412280', 'https://openalex.org/W2031720554', 'https://openalex.org/W2019665678', 'https://openalex.org/W1991910765', 'https://openalex.org/W1122889353'], 'abstract_inverted_index': {'Highly': [0], 'active': [1], 'antiretroviral': [2, 75, 92], 'therapy': [3], '(HAART)': [4], 'based': [5], 'on': [6, 33, 121, 172], 'the': [7, 17, 34, 78, 127, 161, 173, 177, 184, 189, 205, 211, 216, 226, 230, 240, 247], 'combination': [8, 72], 'of': [9, 12, 19, 54, 80, 176, 183, 192, 208], 'different': [10], 'classes': [11], 'inhibitors': [13, 47, 61, 227], 'has': [14], 'dramatically': [15], 'improved': [16], 'prognosis': [18], 'human': [20], 'immunodeficiency': [21], 'virus': [22], 'type': [23], '1': [24], '(HIV-1)': [25], 'infection': [26], 'after': [27], 'its': [28], 'establishment.': [29], 'This': [30], 'chapter': [31], 'focuses': [32], 'viral': [35, 63, 86, 212], 'entry': [36, 245], 'processes': [37], 'that': [38, 126, 159, 188], 'play': [39], 'crucial': [40], 'roles': [41], 'in': [42, 71, 83, 210, 215, 229], 'HIV-1': [43, 82, 99, 150, 244], 'replication': [44], 'and': [45, 62, 113, 135, 141, 156, 199, 219], 'describes': [46], 'thereof.': [48], 'It': [49], 'talks': [50], 'about': [51], 'three': [52], 'kinds': [53], 'inhibitor': [55], 'named': [56], 'as': [57], 'fusion': [58], 'inhibitors,': [59], 'coreceptor': [60], 'attachment': [64], 'inhibitors.': [65], 'Maraviroc': [66], 'was': [67], 'approved': [68], 'for': [69, 77, 115, 165, 243], 'use': [70], 'with': [73, 239], 'other': [74], 'medications': [76], 'treatment': [79, 93], 'R5': [81, 149], 'adults': [84], 'whose': [85], 'loads': [87], 'remain': [88], 'detectable': [89], 'despite': [90], 'existing': [91], 'or': [94, 105], 'who': [95], 'have': [96, 234], 'multidrug-resistant': [97], 'HIV-1.': [98], 'variants': [100, 129], 'resistant': [101, 128], 'to': [102, 107, 123, 133, 143, 154, 197, 225, 237, 246], 'Cyanovirin-N': [103], '(CV-N)': [104], 'cross-resistant': [106], 'additional': [108], 'carbohydrate-binding': [109], 'agents': [110, 167], 'were': [111], 'generated': [112], 'examined': [114], 'their': [116, 170], 'biological': [117], 'properties.': [118], 'A': [119], 'study': [120, 185], 'resistance': [122], 'CV-N': [124], 'demonstrated': [125], 'had': [130], 'increased': [131], 'susceptibility': [132, 153], 'immunoglobulins': [134], 'sera': [136], 'obtained': [137], 'from': [138], 'HIV-1-infected': [139], 'patients': [140], 'particularly': [142], 'V3-loop-directed': [144], 'monoclonal': [145], 'antibodies.': [146], 'The': [147, 181], 'maraviroc-resistant': [148, 193], 'retained': [151], 'full': [152], 'SCH-C': [155], 'aplaviroc,': [157], 'suggesting': [158], 'although': [160], 'CCR5': [162], 'binding': [163], 'sites': [164], 'these': [166], 'are': [168, 179, 195], 'similar,': [169], 'impacts': [171], 'surface': [174], 'conformation': [175], 'receptor': [178], 'different.': [180], 'results': [182], 'also': [186], 'suggest': [187], 'envelope': [190], 'proteins': [191], 'viruses': [194], 'able': [196], 'recognize': [198], 'utilize': [200], 'inhibitor-bound': [201], 'CCR5,': [202], 'which': [203], 'involves': [204], 'ordered': [206], 'accumulation': [207], 'mutations': [209], 'envelope,': [213], 'both': [214], 'V3': [217], 'loop': [218], 'elsewhere': [220], 'within': [221], 'gp120.': [222], 'In': [223], 'addition': [224], 'described': [228], 'chapter,': [231], 'several': [232], 'antibodies': [233], 'been': [235], 'shown': [236], 'interact': [238], 'molecules': [241], 'essential': [242], 'host': [248], 'cells.': [249]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1122889353', 'counts_by_year': [], 'updated_date': '2024-12-14T20:46:02.236712', 'created_date': '2016-06-24'}