Publication Information

{'id': 'https://openalex.org/W110431090', 'doi': 'https://doi.org/10.2165/11596690-000000000-00000', 'title': 'Epigenetic-Based Therapies in Cancer', 'display_name': 'Epigenetic-Based Therapies in Cancer', 'publication_year': 2011, 'publication_date': '2011-12-01', 'ids': {'openalex': 'https://openalex.org/W110431090', 'doi': 'https://doi.org/10.2165/11596690-000000000-00000', 'mag': '110431090', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22141383'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.2165/11596690-000000000-00000', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4436492', 'display_name': 'Drugs', 'issn_l': '0012-6667', 'issn': ['0012-6667', '1179-1950'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080983203', 'display_name': 'Sang‐Hyun Song', 'orcid': 'https://orcid.org/0000-0002-9208-9537'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sang-Hyun Song', 'raw_affiliation_strings': ['Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052823826', 'display_name': 'Sae‐Won Han', 'orcid': 'https://orcid.org/0000-0003-3275-431X'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sae-Won Han', 'raw_affiliation_strings': ['Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5050684671', 'display_name': 'Yung‐Jue Bang', 'orcid': 'https://orcid.org/0000-0001-6000-4597'}, 'institutions': [{'id': 'https://openalex.org/I2802835388', 'display_name': 'Seoul National University Hospital', 'ror': 'https://ror.org/01z4nnt86', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802835388']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yung-Jue Bang', 'raw_affiliation_strings': ['Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehang-ro, Jongno-gu, Seoul, 110-744, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehang-ro, Jongno-gu, Seoul, 110-744, South Korea', 'institution_ids': ['https://openalex.org/I2802835388']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3990, 'currency': 'EUR', 'value_usd': 5290, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.416, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 95, 'citation_normalized_percentile': {'value': 0.666468, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '71', 'issue': '18', 'first_page': '2391', 'last_page': '2403'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11736', 'display_name': 'Histone Deacetylase Inhibitors Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11736', 'display_name': 'Histone Deacetylase Inhibitors Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12534', 'display_name': 'Protein Degradation and Inhibitors', 'score': 0.9737, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/epigenetic-therapy', 'display_name': 'Epigenetic Therapy', 'score': 0.66639227}, {'id': 'https://openalex.org/keywords/cancer-epigenetics', 'display_name': 'Cancer Epigenetics', 'score': 0.592929}, {'id': 'https://openalex.org/keywords/vorinostat', 'display_name': 'Vorinostat', 'score': 0.44537476}, {'id': 'https://openalex.org/keywords/dna-methyltransferase', 'display_name': 'DNA methyltransferase', 'score': 0.42789698}], 'concepts': [{'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.8785197}, {'id': 'https://openalex.org/C2780737395', 'wikidata': 'https://www.wikidata.org/wiki/Q18353741', 'display_name': 'Epigenetic therapy', 'level': 5, 'score': 0.66639227}, {'id': 'https://openalex.org/C64927066', 'wikidata': 'https://www.wikidata.org/wiki/Q36293', 'display_name': 'Histone', 'level': 3, 'score': 0.64897186}, {'id': 'https://openalex.org/C91965660', 'wikidata': 'https://www.wikidata.org/wiki/Q415875', 'display_name': 'Methyltransferase', 'level': 4, 'score': 0.6207247}, {'id': 'https://openalex.org/C114691636', 'wikidata': 'https://www.wikidata.org/wiki/Q5031434', 'display_name': 'Cancer epigenetics', 'level': 5, 'score': 0.592929}, {'id': 'https://openalex.org/C83640560', 'wikidata': 'https://www.wikidata.org/wiki/Q180951', 'display_name': 'Chromatin', 'level': 3, 'score': 0.5895922}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.5707328}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.5080924}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.48466069}, {'id': 'https://openalex.org/C2778305200', 'wikidata': 'https://www.wikidata.org/wiki/Q174378', 'display_name': 'Histone deacetylase', 'level': 4, 'score': 0.48078388}, {'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.46462923}, {'id': 'https://openalex.org/C2776262904', 'wikidata': 'https://www.wikidata.org/wiki/Q905901', 'display_name': 'Vorinostat', 'level': 5, 'score': 0.44537476}, {'id': 'https://openalex.org/C2779979206', 'wikidata': 'https://www.wikidata.org/wiki/Q1154602', 'display_name': 'DNA methyltransferase', 'level': 5, 'score': 0.42789698}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.4258624}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.3838691}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37518856}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2883673}, {'id': 'https://openalex.org/C150425827', 'wikidata': 'https://www.wikidata.org/wiki/Q2560317', 'display_name': 'Histone methyltransferase', 'level': 4, 'score': 0.27395838}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2394388}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.2296454}, {'id': 'https://openalex.org/C33288867', 'wikidata': 'https://www.wikidata.org/wiki/Q518328', 'display_name': 'Methylation', 'level': 3, 'score': 0.21955934}], 'mesh': [{'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015254', 'descriptor_name': 'DNA Modification Methylases', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D044127', 'descriptor_name': 'Epigenesis, Genetic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D020868', 'descriptor_name': 'Gene Silencing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015254', 'descriptor_name': 'DNA Modification Methylases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D015254', 'descriptor_name': 'DNA Modification Methylases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015254', 'descriptor_name': 'DNA Modification Methylases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044127', 'descriptor_name': 'Epigenesis, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.2165/11596690-000000000-00000', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4436492', 'display_name': 'Drugs', 'issn_l': '0012-6667', 'issn': ['0012-6667', '1179-1950'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22141383', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.44, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 96, 'referenced_works': ['https://openalex.org/W1484293540', 'https://openalex.org/W1511815964', 'https://openalex.org/W1519745137', 'https://openalex.org/W1528346173', 'https://openalex.org/W1534726426', 'https://openalex.org/W1563624749', 'https://openalex.org/W1963919702', 'https://openalex.org/W1969323007', 'https://openalex.org/W1972169216', 'https://openalex.org/W1983015568', 'https://openalex.org/W1983293961', 'https://openalex.org/W1989696433', 'https://openalex.org/W1989987919', 'https://openalex.org/W1992039743', 'https://openalex.org/W1992464424', 'https://openalex.org/W1997974036', 'https://openalex.org/W2002788005', 'https://openalex.org/W2005941717', 'https://openalex.org/W2009121506', 'https://openalex.org/W2012508649', 'https://openalex.org/W2013154874', 'https://openalex.org/W2013250198', 'https://openalex.org/W2016419012', 'https://openalex.org/W2017394727', 'https://openalex.org/W2019084941', 'https://openalex.org/W2021424812', 'https://openalex.org/W2022240113', 'https://openalex.org/W2022733644', 'https://openalex.org/W2022734594', 'https://openalex.org/W2024596788', 'https://openalex.org/W2034160841', 'https://openalex.org/W2036216577', 'https://openalex.org/W2036642961', 'https://openalex.org/W2039075718', 'https://openalex.org/W2039915847', 'https://openalex.org/W2046241907', 'https://openalex.org/W2053631011', 'https://openalex.org/W2057916687', 'https://openalex.org/W2060446375', 'https://openalex.org/W2061578142', 'https://openalex.org/W2070484728', 'https://openalex.org/W2070936426', 'https://openalex.org/W2071115015', 'https://openalex.org/W2072855608', 'https://openalex.org/W2081000967', 'https://openalex.org/W2081152501', 'https://openalex.org/W2081159709', 'https://openalex.org/W2081279521', 'https://openalex.org/W2082739830', 'https://openalex.org/W2083535257', 'https://openalex.org/W2086990980', 'https://openalex.org/W2087493660', 'https://openalex.org/W2093315645', 'https://openalex.org/W2093419517', 'https://openalex.org/W2099166288', 'https://openalex.org/W2099678391', 'https://openalex.org/W2106292925', 'https://openalex.org/W2106584820', 'https://openalex.org/W2106775330', 'https://openalex.org/W2109895173', 'https://openalex.org/W2111041465', 'https://openalex.org/W2111907637', 'https://openalex.org/W2112011735', 'https://openalex.org/W2113144329', 'https://openalex.org/W2113950481', 'https://openalex.org/W2114867684', 'https://openalex.org/W2116269315', 'https://openalex.org/W2116960636', 'https://openalex.org/W2117059020', 'https://openalex.org/W2117691193', 'https://openalex.org/W2118771330', 'https://openalex.org/W2122315592', 'https://openalex.org/W2129768414', 'https://openalex.org/W2133124834', 'https://openalex.org/W2135619784', 'https://openalex.org/W2135994759', 'https://openalex.org/W2136032785', 'https://openalex.org/W2141410747', 'https://openalex.org/W2145750252', 'https://openalex.org/W2148033621', 'https://openalex.org/W2152757219', 'https://openalex.org/W2155577690', 'https://openalex.org/W2156334028', 'https://openalex.org/W2156517973', 'https://openalex.org/W2157287007', 'https://openalex.org/W2158582055', 'https://openalex.org/W2158859033', 'https://openalex.org/W2162037712', 'https://openalex.org/W2163710445', 'https://openalex.org/W2168473428', 'https://openalex.org/W2170925020', 'https://openalex.org/W2171365282', 'https://openalex.org/W2511531422', 'https://openalex.org/W4211114385', 'https://openalex.org/W4253412752', 'https://openalex.org/W90521908'], 'related_works': ['https://openalex.org/W4200528065', 'https://openalex.org/W3151757475', 'https://openalex.org/W3023264035', 'https://openalex.org/W2345149559', 'https://openalex.org/W2184344430', 'https://openalex.org/W2145470144', 'https://openalex.org/W2026584824', 'https://openalex.org/W1862292403', 'https://openalex.org/W1513102126', 'https://openalex.org/W1483077634'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W110431090', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 12}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 13}], 'updated_date': '2025-01-05T22:28:15.054213', 'created_date': '2016-06-24'}