Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W110411724', 'doi': 'https://doi.org/10.1016/s0065-2776(08)60228-x', 'title': 'Anaphylatoxins: C3a and C5a', 'display_name': 'Anaphylatoxins: C3a and C5a', 'publication_year': 1978, 'publication_date': '1978-01-01', 'ids': {'openalex': 'https://openalex.org/W110411724', 'doi': 'https://doi.org/10.1016/s0065-2776(08)60228-x', 'mag': '110411724', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/358800'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0065-2776(08)60228-x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S50054696', 'display_name': 'Advances in immunology', 'issn_l': '0065-2776', 'issn': ['0065-2776', '1557-8445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073248837', 'display_name': 'Tony E. Hugli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1311914864', 'display_name': 'Scripps Health', 'ror': 'https://ror.org/05bhsww40', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1311914864']}, {'id': 'https://openalex.org/I4210146328', 'display_name': 'Scripps Clinic', 'ror': 'https://ror.org/05kwjwj05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1311914864', 'https://openalex.org/I4210146328']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tony E. Hugli', 'raw_affiliation_strings': ['Department of Molecular Immunology, Research Institute of Scripps Clinic, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Immunology, Research Institute of Scripps Clinic, La Jolla, California', 'institution_ids': ['https://openalex.org/I1311914864', 'https://openalex.org/I4210146328']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113599416', 'display_name': 'Hans J. Müller‐Eberhard', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146328', 'display_name': 'Scripps Clinic', 'ror': 'https://ror.org/05kwjwj05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1311914864', 'https://openalex.org/I4210146328']}, {'id': 'https://openalex.org/I1311914864', 'display_name': 'Scripps Health', 'ror': 'https://ror.org/05bhsww40', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1311914864']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hans J. Müller-Eberhard', 'raw_affiliation_strings': ['Department of Molecular Immunology, Research Institute of Scripps Clinic, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Immunology, Research Institute of Scripps Clinic, La Jolla, California', 'institution_ids': ['https://openalex.org/I4210146328', 'https://openalex.org/I1311914864']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.241, 'has_fulltext': False, 'cited_by_count': 502, 'citation_normalized_percentile': {'value': 0.941176, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': None, 'issue': None, 'first_page': '1', 'last_page': '53'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11917', 'display_name': 'Coagulation, Bradykinin, Polyphosphates, and Angioedema', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11917', 'display_name': 'Coagulation, Bradykinin, Polyphosphates, and Angioedema', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10993', 'display_name': 'Complement system in diseases', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/anaphylatoxin', 'display_name': 'Anaphylatoxin', 'score': 0.99134266}, {'id': 'https://openalex.org/keywords/cell-type', 'display_name': 'Cell type', 'score': 0.4178351}], 'concepts': [{'id': 'https://openalex.org/C90582226', 'wikidata': 'https://www.wikidata.org/wiki/Q424292', 'display_name': 'Anaphylatoxin', 'level': 4, 'score': 0.99134266}, {'id': 'https://openalex.org/C111684460', 'wikidata': 'https://www.wikidata.org/wiki/Q334848', 'display_name': 'Complement system', 'level': 3, 'score': 0.6592869}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5849801}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.55017763}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.4816529}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.46624106}, {'id': 'https://openalex.org/C14036430', 'wikidata': 'https://www.wikidata.org/wiki/Q3736076', 'display_name': 'Function (biology)', 'level': 2, 'score': 0.45140728}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.42639717}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.41835135}, {'id': 'https://openalex.org/C189014844', 'wikidata': 'https://www.wikidata.org/wiki/Q189118', 'display_name': 'Cell type', 'level': 3, 'score': 0.4178351}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3049006}], 'mesh': [{'descriptor_ui': 'D000706', 'descriptor_name': 'Anaphylatoxins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003176', 'descriptor_name': 'Complement C3', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003182', 'descriptor_name': 'Complement C5', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002633', 'descriptor_name': 'Chemotaxis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003167', 'descriptor_name': 'Complement Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003176', 'descriptor_name': 'Complement C3', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003176', 'descriptor_name': 'Complement C3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003176', 'descriptor_name': 'Complement C3', 'qualifier_ui': 'Q000266', 'qualifier_name': 'history', 'is_major_topic': False}, {'descriptor_ui': 'D003182', 'descriptor_name': 'Complement C5', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003182', 'descriptor_name': 'Complement C5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003182', 'descriptor_name': 'Complement C5', 'qualifier_ui': 'Q000266', 'qualifier_name': 'history', 'is_major_topic': False}, {'descriptor_ui': 'D006168', 'descriptor_name': 'Guinea Pigs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008970', 'descriptor_name': 'Molecular Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009130', 'descriptor_name': 'Muscle, Smooth', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009130', 'descriptor_name': 'Muscle, Smooth', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011487', 'descriptor_name': 'Protein Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012769', 'descriptor_name': 'Shock', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012769', 'descriptor_name': 'Shock', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013045', 'descriptor_name': 'Species Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013552', 'descriptor_name': 'Swine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0065-2776(08)60228-x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S50054696', 'display_name': 'Advances in immunology', 'issn_l': '0065-2776', 'issn': ['0065-2776', '1557-8445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/358800', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.77, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 152, 'referenced_works': ['https://openalex.org/W132399929', 'https://openalex.org/W135904687', 'https://openalex.org/W1488071304', 'https://openalex.org/W1488773749', 'https://openalex.org/W1504321815', 'https://openalex.org/W1510051753', 'https://openalex.org/W1512898564', 'https://openalex.org/W1526721969', 'https://openalex.org/W1537098436', 'https://openalex.org/W1542485172', 'https://openalex.org/W1545103467', 'https://openalex.org/W1548031899', 'https://openalex.org/W1574234279', 'https://openalex.org/W1577219339', 'https://openalex.org/W1579863360', 'https://openalex.org/W1593552287', 'https://openalex.org/W1598475884', 'https://openalex.org/W1613268704', 'https://openalex.org/W1661062552', 'https://openalex.org/W1748026513', 'https://openalex.org/W1755340825', 'https://openalex.org/W1777924595', 'https://openalex.org/W1778005366', 'https://openalex.org/W1833015745', 'https://openalex.org/W1874466664', 'https://openalex.org/W1887261364', 'https://openalex.org/W1896082656', 'https://openalex.org/W18990500', 'https://openalex.org/W1927690319', 'https://openalex.org/W1961046981', 'https://openalex.org/W1964238825', 'https://openalex.org/W1964522162', 'https://openalex.org/W1964899349', 'https://openalex.org/W1965155559', 'https://openalex.org/W1967446411', 'https://openalex.org/W1971501265', 'https://openalex.org/W1973086032', 'https://openalex.org/W1974605004', 'https://openalex.org/W1976662557', 'https://openalex.org/W1977203339', 'https://openalex.org/W1981657190', 'https://openalex.org/W1985590866', 'https://openalex.org/W1987577695', 'https://openalex.org/W1988120134', 'https://openalex.org/W1990130249', 'https://openalex.org/W1991071152', 'https://openalex.org/W1991360728', 'https://openalex.org/W1993500000', 'https://openalex.org/W1995362214', 'https://openalex.org/W1995517313', 'https://openalex.org/W1996511737', 'https://openalex.org/W1996820575', 'https://openalex.org/W1997051322', 'https://openalex.org/W1998750935', 'https://openalex.org/W1999848109', 'https://openalex.org/W2001212493', 'https://openalex.org/W2002276978', 'https://openalex.org/W2002307260', 'https://openalex.org/W2004357920', 'https://openalex.org/W2006094335', 'https://openalex.org/W2006793843', 'https://openalex.org/W2007873275', 'https://openalex.org/W2008531330', 'https://openalex.org/W2009153400', 'https://openalex.org/W2010175077', 'https://openalex.org/W2010856999', 'https://openalex.org/W2012337787', 'https://openalex.org/W2016859255', 'https://openalex.org/W2021200203', 'https://openalex.org/W2023192608', 'https://openalex.org/W2031420933', 'https://openalex.org/W2034202654', 'https://openalex.org/W2034472919', 'https://openalex.org/W2035533586', 'https://openalex.org/W2039345496', 'https://openalex.org/W2040094431', 'https://openalex.org/W2043403577', 'https://openalex.org/W2044615120', 'https://openalex.org/W2044919266', 'https://openalex.org/W2045091174', 'https://openalex.org/W2050412446', 'https://openalex.org/W2051880735', 'https://openalex.org/W2057736960', 'https://openalex.org/W2058526573', 'https://openalex.org/W2058974820', 'https://openalex.org/W2061867028', 'https://openalex.org/W2063570166', 'https://openalex.org/W2067391918', 'https://openalex.org/W2067672041', 'https://openalex.org/W2069102880', 'https://openalex.org/W2071994479', 'https://openalex.org/W2074292789', 'https://openalex.org/W2081255141', 'https://openalex.org/W2081462859', 'https://openalex.org/W2084429434', 'https://openalex.org/W2085157529', 'https://openalex.org/W2086165385', 'https://openalex.org/W2086235020', 'https://openalex.org/W20867046', 'https://openalex.org/W2090109532', 'https://openalex.org/W2093791303', 'https://openalex.org/W2096494712', 'https://openalex.org/W209689489', 'https://openalex.org/W2103464375', 'https://openalex.org/W2104425049', 'https://openalex.org/W2107467160', 'https://openalex.org/W2117228071', 'https://openalex.org/W2120151544', 'https://openalex.org/W2121039245', 'https://openalex.org/W2127831960', 'https://openalex.org/W2131233813', 'https://openalex.org/W2135104268', 'https://openalex.org/W2137470503', 'https://openalex.org/W2150735555', 'https://openalex.org/W2174200965', 'https://openalex.org/W2174235784', 'https://openalex.org/W218049237', 'https://openalex.org/W2287072833', 'https://openalex.org/W2292964384', 'https://openalex.org/W2313860738', 'https://openalex.org/W2314920462', 'https://openalex.org/W2320923764', 'https://openalex.org/W2322899338', 'https://openalex.org/W2325278093', 'https://openalex.org/W2331513080', 'https://openalex.org/W2331513862', 'https://openalex.org/W2331551752', 'https://openalex.org/W2335302374', 'https://openalex.org/W23373441', 'https://openalex.org/W2395546162', 'https://openalex.org/W2396479628', 'https://openalex.org/W2412937947', 'https://openalex.org/W2416144660', 'https://openalex.org/W2416309980', 'https://openalex.org/W3124900447', 'https://openalex.org/W3195424240', 'https://openalex.org/W4243446118', 'https://openalex.org/W4246657713', 'https://openalex.org/W4251406788', 'https://openalex.org/W4256544459', 'https://openalex.org/W4300878749', 'https://openalex.org/W4313307422', 'https://openalex.org/W4313309063', 'https://openalex.org/W4313309147', 'https://openalex.org/W4313310008', 'https://openalex.org/W4313310015', 'https://openalex.org/W4313310264', 'https://openalex.org/W4313311558', 'https://openalex.org/W584365095', 'https://openalex.org/W610122762', 'https://openalex.org/W610523341', 'https://openalex.org/W71912668'], 'related_works': ['https://openalex.org/W83452468', 'https://openalex.org/W4361225438', 'https://openalex.org/W2793625335', 'https://openalex.org/W2418025597', 'https://openalex.org/W2414424409', 'https://openalex.org/W2413844744', 'https://openalex.org/W2092667975', 'https://openalex.org/W2077506189', 'https://openalex.org/W2050499780', 'https://openalex.org/W2010701203'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W110411724', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-06T13:56:21.735197', 'created_date': '2016-06-24'}