Lysosomotropic agents

Name: Work Video:
Duration: 3 min 30 s
Christian de Duve; Thierry de Barsy; Brian D. Poole; André Trouet; Paul M. Tulkens; Fran ̧ois Van Hoof
{'id': 'https://openalex.org/W10640494', 'doi': 'https://doi.org/10.1016/0006-2952(74)90174-9', 'title': 'Lysosomotropic agents', 'display_name': 'Lysosomotropic agents', 'publication_year': 1974, 'publication_date': '1974-09-01', 'ids': {'openalex': 'https://openalex.org/W10640494', 'doi': 'https://doi.org/10.1016/0006-2952(74)90174-9', 'mag': '10640494', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4606365'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0006-2952(74)90174-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S185534594', 'display_name': 'Biochemical Pharmacology', 'issn_l': '0006-2952', 'issn': ['0006-2952', '1873-2968'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113448164', 'display_name': 'Christian de Duve', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95674353', 'display_name': 'UCLouvain', 'ror': 'https://ror.org/02495e989', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I95674353']}, {'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I4210151550', 'display_name': 'Physiol (Belgium)', 'ror': 'https://ror.org/05dwehn62', 'country_code': 'BE', 'type': 'company', 'lineage': ['https://openalex.org/I4210151550']}], 'countries': ['BE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Christian De Duve', 'raw_affiliation_strings': ['Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'The Rockefeller University, New York, NY 10021, U.S.A.'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'institution_ids': ['https://openalex.org/I95674353', 'https://openalex.org/I4210151550']}, {'raw_affiliation_string': 'The Rockefeller University, New York, NY 10021, U.S.A.', 'institution_ids': ['https://openalex.org/I83399316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109934390', 'display_name': 'Thierry de Barsy', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I95674353', 'display_name': 'UCLouvain', 'ror': 'https://ror.org/02495e989', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I95674353']}, {'id': 'https://openalex.org/I4210151550', 'display_name': 'Physiol (Belgium)', 'ror': 'https://ror.org/05dwehn62', 'country_code': 'BE', 'type': 'company', 'lineage': ['https://openalex.org/I4210151550']}], 'countries': ['BE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Thierry De Barsy', 'raw_affiliation_strings': ['Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'The Rockefeller University, New York, NY 10021, U.S.A.'], 'affiliations': [{'raw_affiliation_string': 'The Rockefeller University, New York, NY 10021, U.S.A.', 'institution_ids': ['https://openalex.org/I83399316']}, {'raw_affiliation_string': 'Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'institution_ids': ['https://openalex.org/I95674353', 'https://openalex.org/I4210151550']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017215220', 'display_name': 'Brian D. Poole', 'orcid': 'https://orcid.org/0000-0002-3205-640X'}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I95674353', 'display_name': 'UCLouvain', 'ror': 'https://ror.org/02495e989', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I95674353']}, {'id': 'https://openalex.org/I4210151550', 'display_name': 'Physiol (Belgium)', 'ror': 'https://ror.org/05dwehn62', 'country_code': 'BE', 'type': 'company', 'lineage': ['https://openalex.org/I4210151550']}], 'countries': ['BE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Brian Poole', 'raw_affiliation_strings': ['Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'The Rockefeller University, New York, NY 10021, U.S.A.'], 'affiliations': [{'raw_affiliation_string': 'The Rockefeller University, New York, NY 10021, U.S.A.', 'institution_ids': ['https://openalex.org/I83399316']}, {'raw_affiliation_string': 'Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'institution_ids': ['https://openalex.org/I95674353', 'https://openalex.org/I4210151550']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111486890', 'display_name': 'André Trouet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I95674353', 'display_name': 'UCLouvain', 'ror': 'https://ror.org/02495e989', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I95674353']}, {'id': 'https://openalex.org/I4210151550', 'display_name': 'Physiol (Belgium)', 'ror': 'https://ror.org/05dwehn62', 'country_code': 'BE', 'type': 'company', 'lineage': ['https://openalex.org/I4210151550']}], 'countries': ['BE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Andre´ Trouet', 'raw_affiliation_strings': ['Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'The Rockefeller University, New York, NY 10021, U.S.A.'], 'affiliations': [{'raw_affiliation_string': 'The Rockefeller University, New York, NY 10021, U.S.A.', 'institution_ids': ['https://openalex.org/I83399316']}, {'raw_affiliation_string': 'Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'institution_ids': ['https://openalex.org/I95674353', 'https://openalex.org/I4210151550']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004434922', 'display_name': 'Paul M. Tulkens', 'orcid': 'https://orcid.org/0000-0002-7121-3623'}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I95674353', 'display_name': 'UCLouvain', 'ror': 'https://ror.org/02495e989', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I95674353']}, {'id': 'https://openalex.org/I4210151550', 'display_name': 'Physiol (Belgium)', 'ror': 'https://ror.org/05dwehn62', 'country_code': 'BE', 'type': 'company', 'lineage': ['https://openalex.org/I4210151550']}], 'countries': ['BE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Paul Tulkens', 'raw_affiliation_strings': ['Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'The Rockefeller University, New York, NY 10021, U.S.A.'], 'affiliations': [{'raw_affiliation_string': 'The Rockefeller University, New York, NY 10021, U.S.A.', 'institution_ids': ['https://openalex.org/I83399316']}, {'raw_affiliation_string': 'Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'institution_ids': ['https://openalex.org/I95674353', 'https://openalex.org/I4210151550']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5096973281', 'display_name': 'Fran ̧ois Van Hoof', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151550', 'display_name': 'Physiol (Belgium)', 'ror': 'https://ror.org/05dwehn62', 'country_code': 'BE', 'type': 'company', 'lineage': ['https://openalex.org/I4210151550']}, {'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I95674353', 'display_name': 'UCLouvain', 'ror': 'https://ror.org/02495e989', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I95674353']}], 'countries': ['BE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Fran¸ois Van Hoof', 'raw_affiliation_strings': ['Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'The Rockefeller University, New York, NY 10021, U.S.A.'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Chimie Physiologique, Universite´de Louvain, Belgium', 'institution_ids': ['https://openalex.org/I4210151550', 'https://openalex.org/I95674353']}, {'raw_affiliation_string': 'The Rockefeller University, New York, NY 10021, U.S.A.', 'institution_ids': ['https://openalex.org/I83399316']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3700, 'currency': 'USD', 'value_usd': 3700, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.369, 'has_fulltext': False, 'cited_by_count': 1888, 'citation_normalized_percentile': {'value': 0.977778, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '23', 'issue': '18', 'first_page': '2495', 'last_page': '2531'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11684', 'display_name': 'Vibrio bacteria research studies', 'score': 0.9625, 'subfield': {'id': 'https://openalex.org/subfields/1310', 'display_name': 'Endocrinology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11135', 'display_name': 'Virology and Viral Diseases', 'score': 0.9414, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sindbis-virus', 'display_name': 'Sindbis virus', 'score': 0.80959564}, {'id': 'https://openalex.org/keywords/togaviridae', 'display_name': 'Togaviridae', 'score': 0.6990785}, {'id': 'https://openalex.org/keywords/nitazoxanide', 'display_name': 'Nitazoxanide', 'score': 0.5927532}, {'id': 'https://openalex.org/keywords/alphavirus-infection', 'display_name': 'Alphavirus infection', 'score': 0.54664266}], 'concepts': [{'id': 'https://openalex.org/C2777474056', 'wikidata': 'https://www.wikidata.org/wiki/Q1111605', 'display_name': 'Alphavirus', 'level': 3, 'score': 0.95721185}, {'id': 'https://openalex.org/C2777062976', 'wikidata': 'https://www.wikidata.org/wiki/Q473462', 'display_name': 'Venezuelan equine encephalitis virus', 'level': 4, 'score': 0.92357355}, {'id': 'https://openalex.org/C2777343345', 'wikidata': 'https://www.wikidata.org/wiki/Q2302993', 'display_name': 'Sindbis virus', 'level': 4, 'score': 0.80959564}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.7384144}, {'id': 'https://openalex.org/C2779755945', 'wikidata': 'https://www.wikidata.org/wiki/Q1111605', 'display_name': 'Togaviridae', 'level': 3, 'score': 0.6990785}, {'id': 'https://openalex.org/C2777276848', 'wikidata': 'https://www.wikidata.org/wiki/Q2943789', 'display_name': 'Nitazoxanide', 'level': 2, 'score': 0.5927532}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5805462}, {'id': 'https://openalex.org/C2781313946', 'wikidata': 'https://www.wikidata.org/wiki/Q4735280', 'display_name': 'Alphavirus infection', 'level': 4, 'score': 0.54664266}, {'id': 'https://openalex.org/C2781273456', 'wikidata': 'https://www.wikidata.org/wiki/Q243257', 'display_name': 'Chikungunya', 'level': 3, 'score': 0.4540686}, {'id': 'https://openalex.org/C140704245', 'wikidata': 'https://www.wikidata.org/wiki/Q3933202', 'display_name': 'Viral replication', 'level': 3, 'score': 0.42687893}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.412333}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.19881171}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.08776221}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D008247', 'descriptor_name': 'Lysosomes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000906', 'descriptor_name': 'Antibodies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001424', 'descriptor_name': 'Bacterial Infections', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001424', 'descriptor_name': 'Bacterial Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003911', 'descriptor_name': 'Dextrans', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003911', 'descriptor_name': 'Dextrans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004798', 'descriptor_name': 'Enzymes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004798', 'descriptor_name': 'Enzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006863', 'descriptor_name': 'Hydrogen-Ion Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008081', 'descriptor_name': 'Liposomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008081', 'descriptor_name': 'Liposomes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008247', 'descriptor_name': 'Lysosomes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008247', 'descriptor_name': 'Lysosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008247', 'descriptor_name': 'Lysosomes', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D008566', 'descriptor_name': 'Membranes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008566', 'descriptor_name': 'Membranes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008661', 'descriptor_name': 'Metabolism, Inborn Errors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008661', 'descriptor_name': 'Metabolism, Inborn Errors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010272', 'descriptor_name': 'Parasitic Diseases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010272', 'descriptor_name': 'Parasitic Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010539', 'descriptor_name': 'Permeability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004364', 'descriptor_name': 'Pharmaceutical Preparations', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D004364', 'descriptor_name': 'Pharmaceutical Preparations', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011134', 'descriptor_name': 'Polysaccharides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011134', 'descriptor_name': 'Polysaccharides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011205', 'descriptor_name': 'Povidone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011205', 'descriptor_name': 'Povidone', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013307', 'descriptor_name': 'Streptomycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013307', 'descriptor_name': 'Streptomycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013501', 'descriptor_name': 'Surface-Active Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013501', 'descriptor_name': 'Surface-Active Agents', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014343', 'descriptor_name': 'Trypan Blue', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014343', 'descriptor_name': 'Trypan Blue', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014777', 'descriptor_name': 'Virus Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014777', 'descriptor_name': 'Virus Diseases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0006-2952(74)90174-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S185534594', 'display_name': 'Biochemical Pharmacology', 'issn_l': '0006-2952', 'issn': ['0006-2952', '1873-2968'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4606365', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 128, 'referenced_works': ['https://openalex.org/W1205458192', 'https://openalex.org/W124297753', 'https://openalex.org/W1490356990', 'https://openalex.org/W1495164387', 'https://openalex.org/W1551383822', 'https://openalex.org/W1569589672', 'https://openalex.org/W1611366725', 'https://openalex.org/W1613415979', 'https://openalex.org/W1661968451', 'https://openalex.org/W1756308182', 'https://openalex.org/W1822473883', 'https://openalex.org/W1864777644', 'https://openalex.org/W1868696300', 'https://openalex.org/W1910381255', 'https://openalex.org/W1923572031', 'https://openalex.org/W1926994191', 'https://openalex.org/W1952575201', 'https://openalex.org/W1965133734', 'https://openalex.org/W1968333816', 'https://openalex.org/W1969347482', 'https://openalex.org/W1970968408', 'https://openalex.org/W1972106731', 'https://openalex.org/W1972953404', 'https://openalex.org/W1974255674', 'https://openalex.org/W1975829529', 'https://openalex.org/W1977352447', 'https://openalex.org/W1977439828', 'https://openalex.org/W1983130854', 'https://openalex.org/W1986106238', 'https://openalex.org/W1987096302', 'https://openalex.org/W1987880010', 'https://openalex.org/W1989358490', 'https://openalex.org/W1992266908', 'https://openalex.org/W1992362792', 'https://openalex.org/W1992433346', 'https://openalex.org/W1994088967', 'https://openalex.org/W1995277163', 'https://openalex.org/W1996021681', 'https://openalex.org/W1997121155', 'https://openalex.org/W2002119641', 'https://openalex.org/W2002743620', 'https://openalex.org/W2003018571', 'https://openalex.org/W2004779104', 'https://openalex.org/W2005153466', 'https://openalex.org/W2007029017', 'https://openalex.org/W2010284238', 'https://openalex.org/W2013295182', 'https://openalex.org/W2015369991', 'https://openalex.org/W2016109429', 'https://openalex.org/W2018071671', 'https://openalex.org/W2018374240', 'https://openalex.org/W2019146386', 'https://openalex.org/W2020380573', 'https://openalex.org/W2020522647', 'https://openalex.org/W2022032064', 'https://openalex.org/W2022104366', 'https://openalex.org/W2022383628', 'https://openalex.org/W2025562800', 'https://openalex.org/W2026621781', 'https://openalex.org/W2026839089', 'https://openalex.org/W2027027075', 'https://openalex.org/W2029463562', 'https://openalex.org/W2030793020', 'https://openalex.org/W2037076411', 'https://openalex.org/W2039237628', 'https://openalex.org/W2041193908', 'https://openalex.org/W2041894836', 'https://openalex.org/W2044917112', 'https://openalex.org/W2045894352', 'https://openalex.org/W2047779480', 'https://openalex.org/W2049921340', 'https://openalex.org/W2052135614', 'https://openalex.org/W2053336639', 'https://openalex.org/W2053622155', 'https://openalex.org/W2054825323', 'https://openalex.org/W2057241063', 'https://openalex.org/W2063316977', 'https://openalex.org/W2064078720', 'https://openalex.org/W2067405597', 'https://openalex.org/W2068906023', 'https://openalex.org/W2069004374', 'https://openalex.org/W2070254132', 'https://openalex.org/W2070476309', 'https://openalex.org/W2070865761', 'https://openalex.org/W2071633123', 'https://openalex.org/W2072049177', 'https://openalex.org/W2072136636', 'https://openalex.org/W2072216949', 'https://openalex.org/W2073661241', 'https://openalex.org/W2075636385', 'https://openalex.org/W2076230362', 'https://openalex.org/W2077112916', 'https://openalex.org/W2077824916', 'https://openalex.org/W2080210883', 'https://openalex.org/W2080494706', 'https://openalex.org/W2085181720', 'https://openalex.org/W2085582966', 'https://openalex.org/W2086510909', 'https://openalex.org/W2095116276', 'https://openalex.org/W2096597844', 'https://openalex.org/W2098048990', 'https://openalex.org/W2099427783', 'https://openalex.org/W2101944945', 'https://openalex.org/W2111031157', 'https://openalex.org/W2116240330', 'https://openalex.org/W2121650220', 'https://openalex.org/W2129315553', 'https://openalex.org/W2135449023', 'https://openalex.org/W2138948114', 'https://openalex.org/W2147113738', 'https://openalex.org/W2147126892', 'https://openalex.org/W2159922416', 'https://openalex.org/W2166305071', 'https://openalex.org/W2287559080', 'https://openalex.org/W2322154725', 'https://openalex.org/W2323821639', 'https://openalex.org/W2335407441', 'https://openalex.org/W2346801008', 'https://openalex.org/W2606740596', 'https://openalex.org/W2616321620', 'https://openalex.org/W325197058', 'https://openalex.org/W341581394', 'https://openalex.org/W4235740070', 'https://openalex.org/W4236454521', 'https://openalex.org/W4243202999', 'https://openalex.org/W4254166813', 'https://openalex.org/W4299894474', 'https://openalex.org/W621452571'], 'related_works': ['https://openalex.org/W4283016376', 'https://openalex.org/W4205894010', 'https://openalex.org/W257578036', 'https://openalex.org/W2417321042', 'https://openalex.org/W2118814257', 'https://openalex.org/W2043995584', 'https://openalex.org/W2031204702', 'https://openalex.org/W2009750207', 'https://openalex.org/W1643033222', 'https://openalex.org/W1452174070'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W10640494', 'counts_by_year': [{'year': 2024, 'cited_by_count': 35}, {'year': 2023, 'cited_by_count': 30}, {'year': 2022, 'cited_by_count': 30}, {'year': 2021, 'cited_by_count': 31}, {'year': 2020, 'cited_by_count': 44}, {'year': 2019, 'cited_by_count': 35}, {'year': 2018, 'cited_by_count': 29}, {'year': 2017, 'cited_by_count': 33}, {'year': 2016, 'cited_by_count': 43}, {'year': 2015, 'cited_by_count': 40}, {'year': 2014, 'cited_by_count': 42}, {'year': 2013, 'cited_by_count': 43}, {'year': 2012, 'cited_by_count': 39}], 'updated_date': '2025-01-04T20:30:02.677635', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
