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Results for 'Sterol O-acyltransferase'
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Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor
Publication Year: 2020
DOI: https://doi.org/10.1038/s41467-020-16288-4
Abstract:
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Authors:
Chengcheng Guan
Yange Niu
Si‐Cong Chen
Yunlu Kang
Jing-Xiang Wu
Koji Nishi
Catherine C.Y. Chang
Ta‐Yuan Chang
Tuoping Luo
Lei Chen
Sterol-O-acyltransferase-1 has a role in kidney disease associated with diabetes and Alport syndrome
Publication Year: 2020
DOI: https://doi.org/10.1016/j.kint.2020.06.040
Abstract:
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Authors:
Xiaochen Liu
Gloria Michelle Ducasa
Shamroop Kumar Mallela
Jin‐Ju Kim
Judith Molina
Alla Mitrofanova
Sydney S. Wilbon
Mengyuan Ge
Antonio M. Fontanella
Christopher E. Pedigo
Javier Varona Santos
Robert G. Nelson
Yelena Drexler
Gabriel Contreras
Hassan Al‐Ali
Sandra Merscher
Alessia Fornoni
Sterol O-Acyltransferase 2 Contributes to the Yolk Cholesterol Trafficking during Zebrafish Embryogenesis
Publication Year: 2016
DOI: https://doi.org/10.1371/journal.pone.0167644
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Authors:
Nai-Yun Chang
Yen-Ju Chan
Shih‐Torng Ding
Yen-Hua Lee
Wei‐Chun HuangFu
I‐Hsuan Liu
Sterol O-Acyltransferase 1 (SOAT1, ACAT) Is a Novel Target of Steroidogenic Factor-1 (SF-1, NR5A1, Ad4BP) in the Human Adrenal
Publication Year: 2011
DOI: https://doi.org/10.1210/jc.2010-2021
Abstract:
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Authors:
Bruno Ferraz‐de‐Souza
Rebecca E. Hudson‐Davies
Lin Lin
Rahul Parnaik
Michael Hubank
Mehul Dattani
John C. Achermann
A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma
Publication Year: 2020
DOI: https://doi.org/10.1007/s10637-020-00899-1
Abstract:
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Authors:
David C. Smith
Matthias Kroiß
Electron Kebebew
Mouhammed Amir Habra
Rashmi Chugh
Bryan J. Schneider
Martin Faßnacht
Pegah Jafarinasabian
M. Marian Ijzerman
Vivian Lin
Pharis Mohideen
Aung Naing
Acute Sterol O-Acyltransferase 2 (SOAT2) Knockdown Rapidly Mobilizes Hepatic Cholesterol for Fecal Excretion
Publication Year: 2014
DOI: https://doi.org/10.1371/journal.pone.0098953
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Authors:
Stephanie Marshall
Anthony D. Gromovsky
Kathryn L. Kelley
Matthew A. Davis
Martha D. Wilson
Richard Lee
Rosanne M. Crooke
Mark J. Graham
Lawrence L. Rudel
J. Mark Brown
Ryan E. Temel
7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007
Publication Year: 2016
DOI: https://doi.org/10.1038/ja.2016.27
Abstract:
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Authors:
Ryuji Uchida
Kento Nakajyo
Keisuke Kobayashi
Taichi Ohshiro
Takeshi Terahara
Chiaki Imada
Hiroshi Tomoda
Cholesterol Esters (CE) Derived From Hepatic Sterol O-Acyltransferase 2 (SOAT2) Are Associated With More Atherosclerosis Than CE From Intestinal SOAT2
Publication Year: 2014
DOI: https://doi.org/10.1161/circresaha.115.304378
Abstract:
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Authors:
Jun Zhang
Janet K. Sawyer
Stephanie Marshall
Kathryn L. Kelley
Matthew A. Davis
Martha D. Wilson
J. Mark Brown
Lawrence L. Rudel
Mutations in Sterol O-Acyltransferase 1 (Soat1) Result in Hair Interior Defects in AKR/J Mice
Publication Year: 2010
DOI: https://doi.org/10.1038/jid.2010.168
Abstract:
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Authors:
Baojin Wu
Christopher J. Potter
Kathleen A. Silva
Yanhua Liang
Laura G. Reinholdt
Lydia M. Alley
Lucy B. Rowe
Derry C. Roopenian
Alexander Awgulewitsch
John P. Sundberg
Functional Analysis of Sterol O-Acyltransferase Involved in the Biosynthetic Pathway of Pachymic Acid in Wolfiporia cocos
Publication Year: 2021
DOI: https://doi.org/10.3390/molecules27010143
Abstract:
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Authors:
Wenjun Zhu
Ying Liu
Jing Tang
Heping Liu
Naliang Jing
Fengfeng Li
Ran Xu
Shaohua Shu
Biosynthesis of Phytosterol Esters: Identification of a Sterol <i>O</i>-Acyltransferase in Arabidopsis
Publication Year: 2007
DOI: https://doi.org/10.1104/pp.107.106278
Abstract:
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Authors:
Qilin Chen
Lee Steinhauer
Joe K. Hammerlindl
W. A. Keller
Jitao Zou
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer
Publication Year: 2021
DOI: https://doi.org/10.1016/j.prostaglandins.2021.106537
Abstract:
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Authors:
Yuan Liu
Yeqiang Wang
Sida Hao
Yong Qin
Yuye Wu
TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2
Publication Year: 2014
DOI: https://doi.org/10.1194/jlr.m045922
Abstract:
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Authors:
Camilla Pramfalk
Tiffany A. Melhuish
David Wotton
Zhaoyan Jiang
Mats Eriksson
Paolo Parini
Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp.
Publication Year: 2018
DOI: https://doi.org/10.1016/j.bmcl.2018.03.077
Abstract:
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Authors:
Magie M. Kapojos
Delfly B. Abdjul
Hiroyuki Yamazaki
Taichi Ohshiro
Henki Rotinsulu
Defny S. Wewengkang
Deiske A. Sumilat
Hiroshi Tomoda
Michio Namikoshi
Ryuji Uchida
Pseudopyronine B, an inhibitor of sterol O-acyltransferase, produced by Pseudomonas sp. BYK11209
Publication Year: 2016
DOI: https://doi.org/10.1038/ja.2016.46
Abstract:
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Authors:
Aika Suzuki
Takashi Fukuda
Keisuke Kobayashi
Taichi Ohshiro
Hiroshi Tomoda
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